Carbohydrate supramolecular chemistry: beyond the multivalent effect
González-Cuesta, Manuel, Ortiz Mellet, Carmen, García Fernández, José M
Published in Chemical communications (Cambridge, England) (14.05.2020)
Published in Chemical communications (Cambridge, England) (14.05.2020)
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Journal Article
Glycomimetic-based pharmacological chaperones for lysosomal storage disorders: lessons from Gaucher, GM1-gangliosidosis and Fabry diseases
Sánchez-Fernández, Elena M, García Fernández, José M, Mellet, Carmen Ortiz
Published in Chemical communications (Cambridge, England) (25.04.2016)
Published in Chemical communications (Cambridge, England) (25.04.2016)
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pH-Responsive Pharmacological Chaperones for Rescuing Mutant Glycosidases
Mena-Barragán, Teresa, Narita, Aya, Matias, Dino, Tiscornia, Gustavo, Nanba, Eiji, Ohno, Kousaku, Suzuki, Yoshiyuki, Higaki, Katsumi, Garcia Fernández, José Manuel, Ortiz Mellet, Carmen
Published in Angewandte Chemie (International ed.) (28.09.2015)
Published in Angewandte Chemie (International ed.) (28.09.2015)
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Journal Article
High‐Mannose Oligosaccharide Hemimimetics that Recapitulate the Conformation and Binding Mode to Concanavalin A, DC‐SIGN and Langerin
Herrera‐González, Irene, González‐Cuesta, Manuel, Thépaut, Michel, Laigre, Eugénie, Goyard, David, Rojo, Javier, García Fernández, José M., Fieschi, Franck, Renaudet, Olivier, Nieto, Pedro M., Ortiz Mellet, Carmen
Published in Chemistry : a European journal (08.01.2024)
Published in Chemistry : a European journal (08.01.2024)
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Journal Article
Glycosidase Inhibition with Fullerene Iminosugar Balls: A Dramatic Multivalent Effect
Compain, Philippe, Decroocq, Camille, Iehl, Julien, Holler, Michel, Hazelard, Damien, Mena Barragán, Teresa, Ortiz Mellet, Carmen, Nierengarten, Jean-François
Published in Angewandte Chemie (International ed.) (02.08.2010)
Published in Angewandte Chemie (International ed.) (02.08.2010)
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Journal Article
Modulation of microglia polarization dynamics during diabetic retinopathy in db/db mice
Arroba, Ana I., Alcalde-Estevez, Elena, García-Ramírez, Marta, Cazzoni, Daniele, de la Villa, Pedro, Sánchez-Fernández, Elena M., Mellet, Carmen Ortiz, García Fernández, José M., Hernández, Cristina, Simó, Rafael, Valverde, Ángela M.
Published in Biochimica et biophysica acta (01.09.2016)
Published in Biochimica et biophysica acta (01.09.2016)
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Journal Article
Potent and Selective Cell‐Active Iminosugar Inhibitors of Human α‐N‐Acetylgalactosaminidase (α‐NAGAL)
Ashmus, Roger A., Wang, Yang, González‐Cuesta, Manuel, King, Dustin T., Tiet, Ben, Chen, Xi, Zhu, Yanping, Kirk, Bryce, García Fernandez, José M., Ortiz Mellet, Carmen, Britton, Robert, Vocadlo, David J.
Published in Chemistry : a European journal (04.08.2023)
Published in Chemistry : a European journal (04.08.2023)
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Journal Article
Bicyclic Picomolar OGA Inhibitors Enable Chemoproteomic Mapping of Its Endogenous Post-translational Modifications
González-Cuesta, Manuel, Sidhu, Peter, Ashmus, Roger A, Males, Alexandra, Proceviat, Cameron, Madden, Zarina, Rogalski, Jason C, Busmann, Jil A, Foster, Leonard J, García Fernández, José M, Davies, Gideon J, Ortiz Mellet, Carmen, Vocadlo, David J
Published in Journal of the American Chemical Society (19.01.2022)
Published in Journal of the American Chemical Society (19.01.2022)
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Journal Article
Trifaceted Mickey Mouse Amphiphiles for Programmable Self‐Assembly, DNA Complexation and Organ‐Selective Gene Delivery
Carbajo‐Gordillo, Ana I., González‐Cuesta, Manuel, Jiménez Blanco, José L., Benito, Juan M., Santana‐Armas, María L., Carmona, Thais, Di Giorgio, Christophe, Przybylski, Cédric, Ortiz Mellet, Carmen, Tros de Ilarduya, Conchita, Mendicuti, Francisco, García Fernández, José M.
Published in Chemistry : a European journal (25.06.2021)
Published in Chemistry : a European journal (25.06.2021)
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Journal Article
Mannobioside biomimetics that trigger DC-SIGN binding selectivity
Herrera-González, Irene, Thépaut, Michel, Sánchez-Fernández, Elena M, di Maio, Antonio, Vivès, Corinne, Rojo, Javier, García Fernández, José M, Fieschi, Franck, Nieto, Pedro M, Ortiz Mellet, Carmen
Published in Chemical communications (Cambridge, England) (27.10.2022)
Published in Chemical communications (Cambridge, England) (27.10.2022)
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Journal Article
The Impact of Heteromultivalency in Lectin Recognition and Glycosidase Inhibition: An Integrated Mechanistic Study
García‐Moreno, M. Isabel, Ortega‐Caballero, Fernando, Rísquez‐Cuadro, Rocío, Ortiz Mellet, Carmen, García Fernández, José M.
Published in Chemistry : a European journal (05.05.2017)
Published in Chemistry : a European journal (05.05.2017)
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Journal Article
Cyclodextrin-Based Nanostructure Efficiently Delivers siRNA to Glioblastoma Cells Preferentially via Macropinocytosis
Manzanares, Darío, Pérez-Carrión, María Dolores, Jiménez Blanco, José Luis, Ortiz Mellet, Carmen, García Fernández, José Manuel, Ceña, Valentín
Published in International journal of molecular sciences (06.12.2020)
Published in International journal of molecular sciences (06.12.2020)
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Journal Article
Pharmacological chaperone therapy for Gaucher disease: a patent review
Benito, Juan M, García Fernández, José M, Ortiz Mellet, Carmen
Published in Expert opinion on therapeutic patents (01.06.2011)
Published in Expert opinion on therapeutic patents (01.06.2011)
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Journal Article
Plasmid‐Templated Control of DNA–Cyclodextrin Nanoparticle Morphology through Molecular Vector Design for Effective Gene Delivery
Gallego‐Yerga, Laura, Benito, Juan M., Blanco‐Fernández, Laura, Martínez‐Negro, María, Vélaz, Itziar, Aicart, Emilio, Junquera, Elena, Ortiz Mellet, Carmen, Tros de Ilarduya, Conchita, García Fernández, Jose M.
Published in Chemistry : a European journal (12.03.2018)
Published in Chemistry : a European journal (12.03.2018)
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Journal Article
Mannosyl-coated nanocomplexes from amphiphilic cyclodextrins and pDNA for site-specific gene delivery
Díaz-Moscoso, Alejandro, Guilloteau, Nicolas, Bienvenu, Céline, Méndez-Ardoy, Alejandro, Jiménez Blanco, José L, Benito, Juan M, Le Gourriérec, Loïc, Di Giorgio, Christophe, Vierling, Pierre, Defaye, Jacques, Ortiz Mellet, Carmen, García Fernández, José M
Published in Biomaterials (01.10.2011)
Published in Biomaterials (01.10.2011)
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Journal Article
Polycationic Amphiphilic Cyclodextrins for Gene Delivery: Synthesis and Effect of Structural Modifications on Plasmid DNA Complex Stability, Cytotoxicity, and Gene Expression
Díaz-Moscoso, Alejandro, Le Gourriérec, Löic, Gómez-García, Marta, Benito, Juan M., Balbuena, Patricia, Ortega-Caballero, Fernando, Guilloteau, Nicolas, Di Giorgio, Christophe, Vierling, Pierre, Defaye, Jacques, Ortiz Mellet, Carmen, García Fernández, José M.
Published in Chemistry : a European journal (23.11.2009)
Published in Chemistry : a European journal (23.11.2009)
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Journal Article
Docetaxel-Loaded Nanoparticles Assembled from β-Cyclodextrin/Calixarene Giant Surfactants: Physicochemical Properties and Cytotoxic Effect in Prostate Cancer and Glioblastoma Cells
Gallego-Yerga, Laura, Posadas, Inmaculada, de la Torre, Cristina, Ruiz-Almansa, Jesús, Sansone, Francesco, Ortiz Mellet, Carmen, Casnati, Alessandro, García Fernández, José M, Ceña, Valentín
Published in Frontiers in pharmacology (08.05.2017)
Published in Frontiers in pharmacology (08.05.2017)
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Journal Article
Cyclodextrin-Based Functional Glyconanomaterials
Rivero-Barbarroja, Gonzalo, Benito, Juan Manuel, Ortiz Mellet, Carmen, García Fernández, José Manuel
Published in Nanomaterials (Basel, Switzerland) (15.12.2020)
Published in Nanomaterials (Basel, Switzerland) (15.12.2020)
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Journal Article
Synthesis of High-Mannose Oligosaccharide Analogues through Click Chemistry: True Functional Mimics of Their Natural Counterparts Against Lectins?
François-Heude, Marc, Méndez-Ardoy, Alejandro, Cendret, Virginie, Lafite, Pierre, Daniellou, Richard, Ortiz Mellet, Carmen, García Fernández, José M., Moreau, Vincent, Djedaïni-Pilard, Florence
Published in Chemistry : a European journal (26.01.2015)
Published in Chemistry : a European journal (26.01.2015)
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