Synthesis of sp2-Iminosugar Selenoglycolipids as Multitarget Drug Candidates with Antiproliferative, Leishmanicidal and Anti-Inflammatory Properties
Sánchez-Fernández, Elena M., García-Hernández, Raquel, Gamarro, Francisco, Arroba, Ana I., Aguilar-Diosdado, Manuel, Padrón, José M., García Fernández, José M., Ortiz Mellet, Carmen
Published in Molecules (Basel, Switzerland) (11.12.2021)
Published in Molecules (Basel, Switzerland) (11.12.2021)
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Stereoselective Synthesis of Iminosugar 2‑Deoxy(thio)glycosides from Bicyclic Iminoglycal Carbamates Promoted by Cerium(IV) Ammonium Nitrate and Cooperative Brønsted Acid-Type Organocatalysis
Herrera-González, Irene, Sánchez-Fernández, Elena M, Sau, Abhijit, Nativi, Cristina, García Fernández, José M, Galán, M. Carmen, Ortiz Mellet, Carmen
Published in Journal of organic chemistry (03.04.2020)
Published in Journal of organic chemistry (03.04.2020)
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Host-Guest-Mediated DNA Templation of Polycationic Supramolecules for Hierarchical Nanocondensation and the Delivery of Gene Material
Gallego-Yerga, Laura, Blanco-Fernández, Laura, Urbiola, Koldo, Carmona, Thais, Marcelo, Gema, Benito, Juan M., Mendicuti, Francisco, Tros de Ilarduya, Conchita, Ortiz Mellet, Carmen, García Fernández, José M.
Published in Chemistry : a European journal (17.08.2015)
Published in Chemistry : a European journal (17.08.2015)
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A Bicyclic 1-Deoxygalactonojirimycin Derivative as a Novel Pharmacological Chaperone for GM1 Gangliosidosis
Takai, Tomoko, Higaki, Katsumi, Aguilar-Moncayo, Matilde, Mena-Barragán, Teresa, Hirano, Yuki, Yura, Kei, Yu, Liang, Ninomiya, Haruaki, García-Moreno, M. Isabel, Sakakibara, Yasubumi, Ohno, Kousaku, Nanba, Eiji, Ortiz Mellet, Carmen, García Fernández, José M., Suzuki, Yoshiyuki
Published in Molecular therapy (01.03.2013)
Published in Molecular therapy (01.03.2013)
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Unravelling the Inflammatory Processes in the Early Stages of Diabetic Nephropathy and the Potential Effect of (Ss)-DS-ONJ
Gómez-Jaramillo, Laura, Cano-Cano, Fátima, Sánchez-Fernández, Elena M., Ortiz Mellet, Carmen, García-Fernández, José M., Alcalá, Martín, Álvarez-Gallego, Fabiola, Iturregui, Marta, González-Montelongo, María del Carmen, Campos-Caro, Antonio, Arroba, Ana I., Aguilar-Diosdado, Manuel
Published in International journal of molecular sciences (01.08.2022)
Published in International journal of molecular sciences (01.08.2022)
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Tn Antigen Mimics Based on sp(2)-Iminosugars with Affinity for an anti-MUC1 Antibody
Sanchez Fernandez, Elena M., Navo, Claudio D., Martinez-Saez, Nuria, Goncalves-Pereira, Rita, Somovilla, Victor J., Avenoza, Alberto, Busto, Jesus H., Bernardes, Goncalo J. L., Jimenez-Oses, Gonzalo, Corzana, Francisco, Garcia Fernandez, Jose M., Ortiz Mellet, Carmen, Peregrina, Jesus M.
Published in Organic letters (05.08.2016)
Published in Organic letters (05.08.2016)
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Understanding multivalent effects in glycosidase inhibition using C-glycoside click clusters as molecular probes
Stauffert, Fabien, Bodlenner, Anne, Thi Minh Nguyet Trinh, Isabel Garcia-Moreno, M., Ortiz Mellet, Carmen, Nierengarten, Jean-Francois, Compain, Philippe
Published in New journal of chemistry (01.01.2016)
Published in New journal of chemistry (01.01.2016)
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sp2-Iminosugars targeting human lysosomal β-hexosaminidase as pharmacological chaperone candidates for late-onset Tay-Sachs disease
González-Cuesta, Manuel, Herrera-González, Irene, García-Moreno, M. Isabel, Ashmus, Roger A., Vocadlo, David J., García Fernández, José M., Nanba, Eiji, Higaki, Katsumi, Ortiz Mellet, Carmen
Published in Journal of enzyme inhibition and medicinal chemistry (01.12.2022)
Published in Journal of enzyme inhibition and medicinal chemistry (01.12.2022)
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Probing Carbohydrate-Lectin Recognition in Heterogeneous Environments with Monodisperse Cyclodextrin-Based Glycoclusters
Gómez-García, Marta, Benito, Juan M, Butera, Anna P, Mellet, Carmen Ortiz, Fernández, José M. García, Blanco, José L. Jiménez
Published in Journal of organic chemistry (03.02.2012)
Published in Journal of organic chemistry (03.02.2012)
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Molecular determinants for cyclo-oligosaccharide-based nanoparticle-mediated effective siRNA transfection
Manzanares, Darío, Araya-Durán, Ingrid, Gallego-Yerga, Laura, Játiva, Pablo, Márquez-Miranda, Valeria, Canan, Jonathan, Jiménez Blanco, José Luis, Mellet, Carmen Ortiz, González-Nilo, Fernando Danilo, García Fernández, José Manuel, Ceña, Valentín
Published in Nanomedicine (London, England) (01.07.2017)
Published in Nanomedicine (London, England) (01.07.2017)
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Toward a suitable structural analysis of gene delivery carrier based on polycationic carbohydrates by electron transfer dissociation tandem mass spectrometry
Przybylski, Cédric, Benito, Juan M., Bonnet, Véronique, Mellet, Carmen Ortiz, García Fernández, José M.
Published in Analytica chimica acta (15.12.2016)
Published in Analytica chimica acta (15.12.2016)
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Carbon Dioxide as a Traceless Caramelization Promotor: Preparation of Prebiotic Difructose Dianhydrides (DFAs)-Enriched Caramels from d‑Fructose
Audemar, Maïté, Atencio-Genes, Loyda, Ortiz Mellet, Carmen, Jérôme, François, Garcia Fernandez, José Manuel, De Oliveira Vigier, Karine
Published in Journal of agricultural and food chemistry (02.08.2017)
Published in Journal of agricultural and food chemistry (02.08.2017)
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New castanospermine glycoside analogues inhibit breast cancer cell proliferation and induce apoptosis without affecting normal cells
Allan, Ghada, Ouadid-Ahidouch, Halima, Sanchez-Fernandez, Elena M, Risquez-Cuadro, Rocío, Fernandez, José M Garcia, Ortiz-Mellet, Carmen, Ahidouch, Ahmed
Published in PloS one (04.10.2013)
Published in PloS one (04.10.2013)
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Molecular Basis of 1‑Deoxygalactonojirimycin Arylthiourea Binding to Human α‑Galactosidase A: Pharmacological Chaperoning Efficacy on Fabry Disease Mutants
Yu, Yi, Mena-Barragán, Teresa, Higaki, Katsumi, Johnson, Jennifer L, Drury, Jason E, Lieberman, Raquel L, Nakasone, Naoe, Ninomiya, Haruaki, Tsukimura, Takahiro, Sakuraba, Hitoshi, Suzuki, Yoshiyuki, Nanba, Eiji, Mellet, Carmen Ortiz, García Fernández, José M, Ohno, Kousaku
Published in ACS chemical biology (18.07.2014)
Published in ACS chemical biology (18.07.2014)
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Synthesis of N-, S-, and C-glycoside castanospermine analogues with selective neutral alpha-glucosidase inhibitory activity as antitumour agents
Sanchez-Fernandez, Elena M., Risquez-Cuadro, Rocio, Chasseraud, Maud, Ahidouch, Ahmed, Ortiz Mellet, Carmen, Ouadid-Ahidouch, Halima, Garcia Fernandez, Jose M.
Published in Chemical communications (Cambridge, England) (01.01.2010)
Published in Chemical communications (Cambridge, England) (01.01.2010)
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Generalized Anomeric Effect in Action: Synthesis and Evaluation of Stable Reducing Indolizidine Glycomimetics as Glycosidase Inhibitors
Díaz Pérez, Víctor M, García Moreno, M. Isabel, Ortiz Mellet, Carmen, Fuentes, José, Díaz Arribas, Juan C, Cañada, F. Javier, García Fernández, José M
Published in Journal of organic chemistry (14.01.2000)
Published in Journal of organic chemistry (14.01.2000)
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Journal Article
sp 2 -Iminosugar α-glucosidase inhibitor 1-C-octyl-2-oxa-3-oxocastanospermine specifically affected breast cancer cell migration through Stim1, β1-integrin, and FAK signaling pathways
Gueder, Nahla, Allan, Ghada, Telliez, Marie-Sophie, Hague, Frédéric, Fernandez, José M, Sanchez-Fernandez, Elena M, Ortiz-Mellet, Carmen, Ahidouch, Ahmed, Ouadid-Ahidouch, Halima
Published in Journal of cellular physiology (01.12.2017)
Published in Journal of cellular physiology (01.12.2017)
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Journal Article
sp2‐Iminosugar α‐glucosidase inhibitor 1‐C‐octyl‐2‐oxa‐3‐oxocastanospermine specifically affected breast cancer cell migration through Stim1, β1‐integrin, and FAK signaling pathways
Gueder, Nahla, Allan, Ghada, Telliez, Marie‐Sophie, Hague, Frédéric, Fernandez, José M., Sanchez‐Fernandez, Elena M., Ortiz‐Mellet, Carmen, Ahidouch, Ahmed, Ouadid‐Ahidouch, Halima
Published in Journal of cellular physiology (01.12.2017)
Published in Journal of cellular physiology (01.12.2017)
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Conformationally-Locked N-Glycosides with Selective β-Glucosidase Inhibitory Activity: Identification of a New Non-Iminosugar-Type Pharmacological Chaperone for Gaucher Disease
Castilla, Javier, Rísquez, Rocío, Cruz, Deysi, Higaki, Katsumi, Nanba, Eiji, Ohno, Kousaku, Suzuki, Yoshiyuki, Díaz, Yolanda, Ortiz Mellet, Carmen, García Fernández, José M, Castillón, Sergio
Published in Journal of medicinal chemistry (09.08.2012)
Published in Journal of medicinal chemistry (09.08.2012)
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