Tuning the Topological Landscape of DNA–Cyclodextrin Nanocomplexes by Molecular Design
Neva, Tania, Carbajo‐Gordillo, Ana I., Benito, Juan M., Lana, Hugo, Marcelo, Gema, Ortiz Mellet, Carmen, Tros de Ilarduya, Conchita, Mendicuti, Francisco, García Fernández, José M.
Published in Chemistry : a European journal (26.11.2020)
Published in Chemistry : a European journal (26.11.2020)
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Journal Article
Potent Glycosidase Inhibition with Heterovalent Fullerenes: Unveiling the Binding Modes Triggering Multivalent Inhibition
Abellán Flos, Marta, García Moreno, M. Isabel, Ortiz Mellet, Carmen, García Fernández, Jose Manuel, Nierengarten, Jean-Francois, Vincent, Stéphane P.
Published in Chemistry : a European journal (01.08.2016)
Published in Chemistry : a European journal (01.08.2016)
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The Multivalent Effect in Glycosidase Inhibition: Probing the Influence of Architectural Parameters with Cyclodextrin-based Iminosugar Click Clusters
Decroocq, Camille, Rodríguez-Lucena, David, Russo, Virginie, Mena Barragán, Teresa, Ortiz Mellet, Carmen, Compain, Philippe
Published in Chemistry : a European journal (02.12.2011)
Published in Chemistry : a European journal (02.12.2011)
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Journal Article
Pharmacological Chaperones and Coenzyme Q10 Treatment Improves Mutant β-Glucocerebrosidase Activity and Mitochondrial Function in Neuronopathic Forms of Gaucher Disease
de la Mata, Mario, Cotán, David, Oropesa-Ávila, Manuel, Garrido-Maraver, Juan, Cordero, Mario D, Villanueva Paz, Marina, Delgado Pavón, Ana, Alcocer-Gómez, Elizabet, de Lavera, Isabel, Ybot-González, Patricia, Paula Zaderenko, Ana, Ortiz Mellet, Carmen, García Fernández, José M, Sánchez-Alcázar, José A
Published in Scientific reports (05.06.2015)
Published in Scientific reports (05.06.2015)
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Speeding-up the Determination of Protein–Ligand Affinities by STD NMR: The Reduced Data Set STD NMR Approach (rd-STD NMR)
Rocha, Gabriel, Ramírez-Cárdenas, Jonathan, Padilla-Pérez, M. Carmen, Walpole, Samuel, Nepravishta, Ridvan, García-Moreno, M. Isabel, Sánchez-Fernández, Elena M., Ortiz Mellet, Carmen, Angulo, Jesús, Muñoz-García, Juan C.
Published in Analytical chemistry (Washington) (16.01.2024)
Published in Analytical chemistry (Washington) (16.01.2024)
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Cyclodextrin- and calixarene-based polycationic amphiphiles as gene delivery systems: a structure-activity relationship study
Gallego-Yerga, Laura, Lomazzi, Michela, Franceschi, Valentina, Sansone, Francesco, Mellet, Carmen Ortiz, Donofrio, Gaetano, Casnati, Alessandro, Garcia Fernandez, Jose M.
Published in Organic & biomolecular chemistry (14.02.2015)
Published in Organic & biomolecular chemistry (14.02.2015)
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Journal Article
Preorganized, Macromolecular, Gene-Delivery Systems
Ortiz Mellet, Carmen, Benito, Juan M., García Fernández, José M.
Published in Chemistry : a European journal (18.06.2010)
Published in Chemistry : a European journal (18.06.2010)
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Journal Article
Glycoligand-targeted core-shell nanospheres with tunable drug release profiles from calixarene-cyclodextrin heterodimers
Gallego-Yerga, Laura, Lomazzi, Michela, Sansone, Francesco, Ortiz Mellet, Carmen, Casnati, Alessandro, Garcia Fernandez, Jose M.
Published in Chemical communications (Cambridge, England) (18.07.2014)
Published in Chemical communications (Cambridge, England) (18.07.2014)
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Journal Article
Multivalency as an action principle in multimodal lectin recognition and glycosidase inhibition: a paradigm shift driven by carbon-based glyconanomaterials
Ortiz Mellet, Carmen, Nierengarten, Jean-François, García Fernández, José M
Published in Journal of materials chemistry. B, Materials for biology and medicine (2017)
Published in Journal of materials chemistry. B, Materials for biology and medicine (2017)
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Journal Article
Revealing cooperative binding of polycationic cyclodextrins with DNA oligomers by capillary electrophoresis coupled to mass spectrometry
Przybylski, Cédric, Benito, Juan M., Bonnet, Véronique, Mellet, Carmen Ortiz, García Fernández, José M.
Published in Analytica chimica acta (09.03.2018)
Published in Analytica chimica acta (09.03.2018)
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Journal Article
Multivalent glycoligands with lectin/enzyme dual specificity: self-deliverable glycosidase regulators
González-Cuesta, Manuel, Goyard, David, Nanba, Eiji, Higaki, Katsumi, García Fernández, José M, Renaudet, Olivier, Ortiz Mellet, Carmen
Published in Chemical communications (Cambridge, England) (2019)
Published in Chemical communications (Cambridge, England) (2019)
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Journal Article
Reversible Light-Induced Dimerization of Secondary Face Azobenzene-Functionalized β‑Cyclodextrin Derivatives
Rivero-Barbarroja, Gonzalo, Fernández-Clavero, Carlos, García-Iriepa, Cristina, Marcelo, Gema, Padilla-Pérez, M. Carmen, Neva, Tania, Benito, Juan M., Maisonneuve, Stéphane, Ortiz Mellet, Carmen, Xie, Juan, García Fernández, José M., Mendicuti, Francisco
Published in Journal of organic chemistry (07.07.2023)
Published in Journal of organic chemistry (07.07.2023)
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Synthesis, conformational analysis and in vivo assays of an anti-cancer vaccine that features an unnatural antigen based on an sp2-iminosugar fragment
Bermejo, Iris A., Navo, Claudio D., Castro-Lopez, Jorge, Guerreiro, Ana, Jimenez-Moreno, Ester, Fernandez, Elena M. Sanchez, Garcia-Martin, Fayna, Hinou, Hiroshi, Nishimura, Shin-Ichiro, Fernandez, Jose M. Garcia, Mellet, Carmen Ortiz, Avenoza, Alberto, Busto, Jesus H., Bernardes, Goncalo J. L., Hurtado-Guerrero, Ramon, Peregrina, Jesus M., Corzana, Francisco
Published in Chemical science (Cambridge) (27.03.2020)
Published in Chemical science (Cambridge) (27.03.2020)
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Journal Article
sp2-Iminosugar azobenzene O-glycosides: Light-sensitive glycosidase inhibitors with unprecedented tunability and switching factors
Rivero-Barbarroja, Gonzalo, Carmen Padilla-Pérez, M., Maisonneuve, Stéphane, Isabel García-Moreno, M., Tiet, Ben, Vocadlo, David J., Xie, Juan, García Fernández, José M., Ortiz Mellet, Carmen
Published in Bioorganic chemistry (01.09.2024)
Published in Bioorganic chemistry (01.09.2024)
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Journal Article
Giant Glycosidase Inhibitors: First‐ and Second‐Generation Fullerodendrimers with a Dense Iminosugar Shell
Nierengarten, Jean‐François, Schneider, Jérémy P., Trinh, Thi Minh Nguyet, Joosten, Antoine, Holler, Michel, Lepage, Mathieu L., Bodlenner, Anne, García‐Moreno, M. Isabel, Ortiz Mellet, Carmen, Compain, Philippe
Published in Chemistry : a European journal (16.02.2018)
Published in Chemistry : a European journal (16.02.2018)
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Journal Article
Enhanced Gene Delivery Triggered by Dual pH/Redox Responsive Host‐Guest Dimerization of Cyclooligosaccharide Star Polycations
Carbajo‐Gordillo, Ana I., López‐Fernández, José, Benito, Juan M., Jiménez Blanco, José L., Santana‐Armas, María L., Marcelo, Gema, Di Giorgio, Christophe, Przybylski, Cédric, Ortiz Mellet, Carmen, Tros de Ilarduya, Conchita, Mendicuti, Francisco, García Fernández, José M.
Published in Macromolecular rapid communications. (01.06.2022)
Published in Macromolecular rapid communications. (01.06.2022)
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Rational design of cell active C2-modified DGJ analogues for the inhibition of human α-galactosidase A (GALA)
Ashmus, Roger A, Wang, Yang, González-Cuesta, Manuel, King, Dustin T, Tiet, Ben, Gilormini, Pierre-André, García Fernández, José M, Ortiz Mellet, Carmen, Britton, Robert, Vocadlo, David J
Published in Organic & biomolecular chemistry (29.09.2021)
Published in Organic & biomolecular chemistry (29.09.2021)
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Journal Article
sp(2)-Iminosugar glycolipids as inhibitors of lipopolysaccharide-mediated human dendritic cell activation in vitro and of acute inflammation in mice in vivo
Schaeffer, Evelyne, Sanchez-Fernandez, Elena M., Goncalves-Pereira, Rita, Flacher, Vincent, Lamon, Delphine, Duval, Monique, Fauny, Jean-Daniel, Garcia Fernandez, Jose M., Mueller, Christopher G., Mellet, Carmen Ortiz
Published in European journal of medicinal chemistry (01.05.2019)
Published in European journal of medicinal chemistry (01.05.2019)
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Journal Article
A versatile stereocontrolled synthesis of 2-deoxyiminosugar C-glycosides and their evaluation as glycosidase inhibitors
Lumbroso, Alexandre, Berthonneau, Clement, Beaudet, Isabelle, Quintard, Jean-Paul, Planchat, Aurelien, Isabel Garcia-Moreno, M., Ortiz Mellet, Carmen, Le Grognec, Erwan
Published in Organic & biomolecular chemistry (07.02.2021)
Published in Organic & biomolecular chemistry (07.02.2021)
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Journal Article
Trehalose-based Siamese twin amphiphiles with tunable self-assembling, DNA nanocomplexing and gene delivery properties
Carbajo-Gordillo, Ana I, Rodríguez-Lavado, Julio, Jiménez Blanco, José Luis, Benito, Juan M, Di Giorgio, Christophe, Vélaz, Itziar, Tros de Ilarduya, Concepción, Ortiz Mellet, Carmen, García Fernández, José M
Published in Chemical communications (Cambridge, England) (11.07.2019)
Published in Chemical communications (Cambridge, England) (11.07.2019)
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