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3,3-Difluoro-pyrrolidin-1-yl)-[(2S,4S)-(4-(4-pyrimidin-2-yl-piperazin-1-yl)-pyrrolidin-2-yl]-methanone: a potent, selective, orally active dipeptidyl peptidase IV inhibitor
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Published in Bioorganic & medicinal chemistry letters (01.04.2009)
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(3R,4S)-4-(2,4,5-Trifluorophenyl)-pyrrolidin-3-ylamine inhibitors of dipeptidyl peptidase IV: Synthesis, in vitro, in vivo, and X-ray crystallographic characterization
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Published in Bioorganic & medicinal chemistry letters (15.10.2007)
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3,3-Difluoro-pyrrolidin-1-yl)-[(2S,4S)-(4-(4-pyrimidin-2-yl-piperazin-1-yl)-pyrrolidin-2-yl]-methanone: A potent, selective, orally active dipeptidyl peptidase IV inhibitor
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Published in Bioorganic & medicinal chemistry letters (01.04.2009)
Published in Bioorganic & medicinal chemistry letters (01.04.2009)
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Severe diabetes, age-dependent loss of adipose tissue, and mild growth deficiency in mice lacking Akt2/PKB beta
Garofalo, R S, Orena, S J, Rafidi, K, Torchia, A J, Stock, J L, Hildebrandt, AL, Coskran, T, Black, S C, Brees, D J, Wicks, J R, McNeish, J D, Coleman, K G
Published in The Journal of clinical investigation (01.07.2003)
Published in The Journal of clinical investigation (01.07.2003)
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(3,3-Difluoro-pyrrolidin-1-yl)-[(2S,4S)-4-(4-pyrimidin-2-yl-piperazin-1-yl)-pyrrolidin-2-yl]-methanone : A potent, selective, orally active dipeptidyl peptidase IV inhibitor
AMMIRATI, Mark J, ANDREWS, Kim M, PARKER, Janice C, POLIVKOVA, Jana, XIAYANG QIU, SOGLIA, Carolyn B, TREADWAY, Judith L, VANVOLKENBURG, Maria A, WILDER, Donald C, PIOTROWSKI, David W, BOYER, David D, BRODEUR, Anne M, DANLEY, Dennis E, DORAN, Shawn D, HULIN, Bernard, SHENPING LIU, KIRK MCPHERSON, R, ORENA, Stephen J
Published in Bioorganic & medicinal chemistry letters (2009)
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Published in Bioorganic & medicinal chemistry letters (2009)
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LiCl Stimulates Glycogen Synthase and Glucose Transport via Distinct Mechanisms in 3T3-L1 Adipocytes
GAROFALO, ROBERT S, ORENA, STEPHEN J, TORCHIA, ANTHONY J
Published in Diabetes (New York, N.Y.) (01.05.1999)
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Published in Diabetes (New York, N.Y.) (01.05.1999)
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Binding and uptake of copper from ceruloplasmin
Orena, Stephen J., Goode, Christina A., Linder, Maria C.
Published in Biochemical and biophysical research communications (14.09.1986)
Published in Biochemical and biophysical research communications (14.09.1986)
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