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Orally active inhibitors of human leukocyte elastase. I. Disposition of L-683,845 in rats and rhesus monkeys
Vincent, S H, Painter, S K, Krieter, P A, Colletti, A E, Lyszack, E, Rosegay, A, Dean, D, Luffer-Atlas, D, Miller, R R, Cioffe, C, Chiu, S H
Published in Drug metabolism and disposition (01.12.1996)
Published in Drug metabolism and disposition (01.12.1996)
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Biochemical and pharmacological characterization of YM-60828, a newly synthesized and orally active inhibitor of human factor Xa
Taniuchi, Y, Sakai, Y, Hisamichi, N, Kayama, M, Mano, Y, Sato, K, Hirayama, F, Koshio, H, Matsumoto, Y, Kawasaki, T
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Published in Thrombosis and haemostasis (01.03.1998)
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Effects of SCH 34826, an orally active inhibitor of atrial natriuretic peptide degradation, in healthy volunteers
Burnier, M, Ganslmayer, M, Perret, F, Porchet, M, Kosoglou, T, Gould, A, Nussberger, J, Waeber, B, Brunner, H R
Published in Clinical pharmacology and therapeutics (01.08.1991)
Published in Clinical pharmacology and therapeutics (01.08.1991)
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Design, Optimization, and Pre-Clinical Evaluation of Direct, Mechanism-Based STAT3 Inhibitors for Treating Myeloid Disorders
Heaton, William L., Eiring, Anna M., Vellore, Nadeem A., Resetca, Diana, Haftchenary, Sina, Rosa, David, Ali, Ahmed M., Senina, Anna V., Pomicter, Anthony D., Page, Brent D.G., Kraft, Ira L., Reynolds, Kimberly R., Wilson, Derek J., Baron, Riccardo, O’Hare, Thomas, Gunning, Patrick T., Deininger, Michael W.
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Published in Blood (06.12.2014)
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Pharmacokinetics and pharmacodynamics of dapagliflozin, a novel selective inhibitor of sodium-glucose co-transporter type 2, in Japanese subjects without and with type 2 diabetes mellitus
Kasichayanula, S, Chang, M, Hasegawa, M, Liu, X, Yamahira, N, LaCreta, F.P, Imai, Y, Boulton, D.W
Published in Diabetes, obesity & metabolism (01.04.2011)
Published in Diabetes, obesity & metabolism (01.04.2011)
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Effect of ketoconazole and diltiazem on the pharmacokinetics of apixaban, an oral direct factor Xa inhibitor
Frost, Charles E., Byon, Wonkyung, Song, Yan, Wang, Jessie, Schuster, Alan E., Boyd, Rebecca A., Zhang, Donglu, Yu, Zhigang, Dias, Clapton, Shenker, Andrew, LaCreta, Frank
Published in British journal of clinical pharmacology (01.05.2015)
Published in British journal of clinical pharmacology (01.05.2015)
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METABOLISM AND EXCRETION OF ERLOTINIB, A SMALL MOLECULE INHIBITOR OF EPIDERMAL GROWTH FACTOR RECEPTOR TYROSINE KINASE, IN HEALTHY MALE VOLUNTEERS
Ling, Jie, Johnson, Kim A., Miao, Zhuang, Rakhit, Ashok, Pantze, Michael P., Hamilton, Marta, Lum, Bert L., Prakash, Chandra
Published in Drug metabolism and disposition (01.03.2006)
Published in Drug metabolism and disposition (01.03.2006)
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Population pharmacokinetics and pharmacodynamics of edoxaban in pediatric patients
Zou, Peng, Atluri, Akhilesh, Chang, Peter, Goedecke, Michael, Leil, Tarek A.
Published in CPT: pharmacometrics and systems pharmacology (01.01.2025)
Published in CPT: pharmacometrics and systems pharmacology (01.01.2025)
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Safety and Efficacy of an Oral Inhibitor of the Purinergic Receptor P2X7 in Adult Patients with Moderately to Severely Active Crohnʼs Disease: A Randomized Placebo-controlled, Double-blind, Phase IIa Study
Eser, Alexander, Colombel, Jean-Frederic, Rutgeerts, Paul, Vermeire, Severine, Vogelsang, Harald, Braddock, Martin, Persson, Tore, Reinisch, Walter
Published in Inflammatory bowel diseases (01.10.2015)
Published in Inflammatory bowel diseases (01.10.2015)
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The Absolute Oral Bioavailability and??Population-Based Pharmacokinetic Modelling of a Novel Dipeptidylpeptidase-IV Inhibitor, Vildagliptin, in Healthy Volunteers
He, Yan-Ling, Sadler, Brian M, Sabo, Ron, Balez, Sebastien, Wang, Yibin, Campestrini, Joelle, Laurent, Aziz, Ligueros-Saylan, Monica, Howard, Dan
Published in Clinical pharmacokinetics (01.01.2007)
Published in Clinical pharmacokinetics (01.01.2007)
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Inhibition of Dipeptidyl Peptidase IV Improves Metabolic Control Over a 4-Week Study Period in Type 2 Diabetes
Ahrén, Bo, Simonsson, Erik, Larsson, Hillevi, Landin-Olsson, Mona, Torgeirsson, Hlin, Jansson, Per-Anders, Sandqvist, Madeléne, Båvenholm, Peter, Efendic, Suad, Eriksson, Jan W., Dickinson, Sheila, Holmes, David
Published in Diabetes care (01.05.2002)
Published in Diabetes care (01.05.2002)
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Relative bioavailability and safety profile of gefitinib administered as a tablet or as a dispersion preparation via drink or nasogastric tube: results of a randomized, open-label, three-period crossover study in healthy volunteers
Cantarini, Mireille V., McFarquhar, Teresa, Smith, Robert P., Bailey, Chris, Marshall, Anna L.
Published in Clinical therapeutics (01.10.2004)
Published in Clinical therapeutics (01.10.2004)
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Phase II open label study of the oral vascular endothelial growth factor-receptor inhibitor PTK787/ZK222584 (vatalanib) in adult patients with refractory or relapsed diffuse large B-cell lymphoma
Brander, Danielle, Rizzieri, David, Gockerman, Jon, Diehl, Louis, Shea, Thomas Charles, Decastro, Carlos, Moore, Joseph O., Beaven, Anne
Published in Leukemia & lymphoma (01.12.2013)
Published in Leukemia & lymphoma (01.12.2013)
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Abstract P1-18-17: Phase I study of cfi-402257, an oral ttk inhibitor, in patients with advanced solid tumors with breast cancer expansion cohorts
Hilton, John, Renouf, Daniel J, Cescon, David W, Hansen, Aaron R, Razak, Albiruni RA, Stayner, Lee-Anne, Denny, Trisha, Fletcher, Graham, Mak, Tak W, Bray, Mark, Bedard, Philippe L
Published in Cancer research (Chicago, Ill.) (15.02.2022)
Published in Cancer research (Chicago, Ill.) (15.02.2022)
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Pharmacokinetics of captopril in healthy subjects and in patients with cardiovascular diseases
Duchin, K L, McKinstry, D N, Cohen, A I, Migdalof, B H
Published in Clinical pharmacokinetics (01.04.1988)
Published in Clinical pharmacokinetics (01.04.1988)
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