Systems genetics in diversity outbred mice inform BMD GWAS and identify determinants of bone strength
Al-Barghouthi, Basel M., Mesner, Larry D., Calabrese, Gina M., Brooks, Daniel, Tommasini, Steven M., Bouxsein, Mary L., Horowitz, Mark C., Rosen, Clifford J., Nguyen, Kevin, Haddox, Samuel, Farber, Emily A., Onengut-Gumuscu, Suna, Pomp, Daniel, Farber, Charles R.
Published in Nature communications (07.06.2021)
Published in Nature communications (07.06.2021)
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Journal Article
Heterogeneous long‐term trajectories of glycaemic control in type 1 diabetes
Miller, Rachel G., Orchard, Trevor J., Onengut‐Gumuscu, Suna, Chen, Wei‐Min, Rich, Stephen S., Costacou, Tina
Published in Diabetic medicine (01.08.2021)
Published in Diabetic medicine (01.08.2021)
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Journal Article
ELMO1 signaling is a promoter of osteoclast function and bone loss
Arandjelovic, Sanja, Perry, Justin S. A., Zhou, Ming, Ceroi, Adam, Smirnov, Igor, Walk, Scott F., Shankman, Laura S., Cambré, Isabelle, Onengut-Gumuscu, Suna, Elewaut, Dirk, Conrads, Thomas P., Ravichandran, Kodi S.
Published in Nature communications (17.08.2021)
Published in Nature communications (17.08.2021)
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Journal Article
Genetic variants in the complement system and their potential link in the aetiology of type 1 diabetes
Onengut‐Gumuscu, Suna, Webb‐Robertson, Bobbie‐Jo M., Sarkar, Soumyadeep, Manichaikul, Ani, Hu, Xiaowei, Frazer‐Abel, Ashley, Holers, V. Michael, Rewers, Marian J., Rich, Stephen S.
Published in Diabetes/metabolism research and reviews (01.01.2024)
Published in Diabetes/metabolism research and reviews (01.01.2024)
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Journal Article
Single-Cell Transcriptomics of Bone Marrow Stromal Cells in Diversity Outbred Mice: A Model for Population-Level scRNA-Seq Studies
Dillard, Luke J, Rosenow, Will T, Calabrese, Gina M, Mesner, Larry D, Al-Barghouthi, Basel M, Abood, Abdullah, Farber, Emily A, Onengut-Gumuscu, Suna, Tommasini, Steven M, Horowitz, Mark A, Rosen, Clifford J, Yao, Lutian, Qin, Ling, Farber, Charles R
Published in Journal of bone and mineral research (01.09.2023)
Published in Journal of bone and mineral research (01.09.2023)
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Journal Article
A Method for Gene-Based Pathway Analysis Using Genomewide Association Study Summary Statistics Reveals Nine New Type 1 Diabetes Associations
Evangelou, Marina, Smyth, Deborah J., Fortune, Mary D., Burren, Oliver S., Walker, Neil M., Guo, Hui, Onengut-Gumuscu, Suna, Chen, Wei-Min, Concannon, Patrick, Rich, Stephen S., Todd, John A., Wallace, Chris
Published in Genetic epidemiology (01.12.2014)
Published in Genetic epidemiology (01.12.2014)
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Journal Article
Imputing amino acid polymorphisms in human leukocyte antigens
Jia, Xiaoming, Han, Buhm, Onengut-Gumuscu, Suna, Chen, Wei-Min, Concannon, Patrick J, Rich, Stephen S, Raychaudhuri, Soumya, de Bakker, Paul I W
Published in PloS one (06.06.2013)
Published in PloS one (06.06.2013)
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Journal Article
Macrophages redirect phagocytosis by non-professional phagocytes and influence inflammation
Han, Claudia Z., Juncadella, Ignacio J., Kinchen, Jason M., Buckley, Monica W., Klibanov, Alexander L., Dryden, Kelly, Onengut-Gumuscu, Suna, Erdbrügger, Uta, Turner, Stephen D., Shim, Yun M., Tung, Kenneth S., Ravichandran, Kodi S.
Published in Nature (London) (24.11.2016)
Published in Nature (London) (24.11.2016)
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Journal Article
Additive and interaction effects at three amino acid positions in HLA-DQ and HLA-DR molecules drive type 1 diabetes risk
Hu, Xinli, Deutsch, Aaron J, Lenz, Tobias L, Onengut-Gumuscu, Suna, Han, Buhm, Chen, Wei-Min, Howson, Joanna M M, Todd, John A, de Bakker, Paul I W, Rich, Stephen S, Raychaudhuri, Soumya
Published in Nature genetics (01.08.2015)
Published in Nature genetics (01.08.2015)
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Journal Article
The active contribution of OPCs to neuroinflammation is mediated by LRP1
Fernández-Castañeda, Anthony, Chappell, Megan S., Rosen, Dorian A, Seki, Scott M., Beiter, Rebecca M., Johanson, David M., Liskey, Delaney, Farber, Emily, Onengut-Gumuscu, Suna, Overall, Christopher C., Dupree, Jeffrey L., Gaultier, Alban
Published in Acta neuropathologica (01.02.2020)
Published in Acta neuropathologica (01.02.2020)
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Journal Article
Cytomegalovirus infection enhances the immune response to influenza
Furman, David, Jojic, Vladimir, Sharma, Shalini, Shen-Orr, Shai S, Angel, Cesar J L, Onengut-Gumuscu, Suna, Kidd, Brian A, Maecker, Holden T, Concannon, Patrick, Dekker, Cornelia L, Thomas, Paul G, Davis, Mark M
Published in Science translational medicine (01.04.2015)
Published in Science translational medicine (01.04.2015)
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Journal Article
Interpreting an apoptotic corpse as anti-inflammatory involves a chloride sensing pathway
Perry, Justin S. A., Morioka, Sho, Medina, Christopher B., Iker Etchegaray, J., Barron, Brady, Raymond, Michael H., Lucas, Christopher D., Onengut-Gumuscu, Suna, Delpire, Eric, Ravichandran, Kodi S.
Published in Nature cell biology (01.12.2019)
Published in Nature cell biology (01.12.2019)
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Journal Article
Neuromedin B Expression Defines the Mouse Retrotrapezoid Nucleus
Shi, Yingtang, Stornetta, Ruth L, Stornetta, Daniel S, Onengut-Gumuscu, Suna, Farber, Emily A, Turner, Stephen D, Guyenet, Patrice G, Bayliss, Douglas A
Published in The Journal of neuroscience (29.11.2017)
Published in The Journal of neuroscience (29.11.2017)
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Journal Article
Fine-mapping and functional studies highlight potential causal variants for rheumatoid arthritis and type 1 diabetes
Westra, Harm-Jan, Martínez-Bonet, Marta, Onengut-Gumuscu, Suna, Lee, Annette, Luo, Yang, Teslovich, Nikola, Worthington, Jane, Martin, Javier, Huizinga, Tom, Klareskog, Lars, Rantapaa-Dahlqvist, Solbritt, Chen, Wei-Min, Quinlan, Aaron, Todd, John A., Eyre, Steve, Nigrovic, Peter A., Gregersen, Peter K., Rich, Stephen S., Raychaudhuri, Soumya
Published in Nature genetics (01.10.2018)
Published in Nature genetics (01.10.2018)
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Journal Article
Role of Type 1 Diabetes-Associated SNPs on Risk of Autoantibody Positivity in the TEDDY Study
Törn, Carina, Hadley, David, Lee, Hye-Seung, Hagopian, William, Lernmark, Åke, Simell, Olli, Rewers, Marian, Ziegler, Anette, Schatz, Desmond, Akolkar, Beena, Onengut-Gumuscu, Suna, Chen, Wei-Min, Toppari, Jorma, Mykkänen, Juha, Ilonen, Jorma, Rich, Stephen S, She, Jin-Xiong, Steck, Andrea K, Krischer, Jeffrey
Published in Diabetes (New York, N.Y.) (01.05.2015)
Published in Diabetes (New York, N.Y.) (01.05.2015)
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Journal Article
Widespread non-additive and interaction effects within HLA loci modulate the risk of autoimmune diseases
Lenz, Tobias L, Deutsch, Aaron J, Han, Buhm, Hu, Xinli, Okada, Yukinori, Eyre, Stephen, Knapp, Michael, Zhernakova, Alexandra, Huizinga, Tom W J, Abecasis, Gonçalo, Becker, Jessica, Boeckxstaens, Guy E, Chen, Wei-Min, Franke, Andre, Gladman, Dafna D, Gockel, Ines, Gutierrez-Achury, Javier, Martin, Javier, Nair, Rajan P, Nöthen, Markus M, Onengut-Gumuscu, Suna, Rahman, Proton, Rantapää-Dahlqvist, Solbritt, Stuart, Philip E, Tsoi, Lam C, van Heel, David A, Worthington, Jane, Wouters, Mira M, Klareskog, Lars, Elder, James T, Gregersen, Peter K, Schumacher, Johannes, Rich, Stephen S, Wijmenga, Cisca, Sunyaev, Shamil R, de Bakker, Paul I W, Raychaudhuri, Soumya
Published in Nature genetics (01.09.2015)
Published in Nature genetics (01.09.2015)
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Journal Article
Functional IL6R 358Ala allele impairs classical IL-6 receptor signaling and influences risk of diverse inflammatory diseases
Ferreira, Ricardo C, Freitag, Daniel F, Cutler, Antony J, Howson, Joanna M M, Rainbow, Daniel B, Smyth, Deborah J, Kaptoge, Stephen, Clarke, Pamela, Boreham, Charlotte, Coulson, Richard M, Pekalski, Marcin L, Chen, Wei-Min, Onengut-Gumuscu, Suna, Rich, Stephen S, Butterworth, Adam S, Malarstig, Anders, Danesh, John, Todd, John A
Published in PLoS genetics (01.04.2013)
Published in PLoS genetics (01.04.2013)
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Journal Article
Meta-analysis of Immunochip data of four autoimmune diseases reveals novel single-disease and cross-phenotype associations
Márquez, Ana, Kerick, Martin, Zhernakova, Alexandra, Gutierrez-Achury, Javier, Chen, Wei-Min, Onengut-Gumuscu, Suna, González-Álvaro, Isidoro, Rodriguez-Rodriguez, Luis, Rios-Fernández, Raquel, González-Gay, Miguel A, Mayes, Maureen D, Raychaudhuri, Soumya, Rich, Stephen S, Wijmenga, Cisca, Martín, Javier
Published in Genome medicine (20.12.2018)
Published in Genome medicine (20.12.2018)
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Journal Article
Leveraging type 1 diabetes human genetic and genomic data in the T1D knowledge portal
Kudtarkar, Parul, Costanzo, Maria C, Sun, Ying, Jang, Dongkeun, Koesterer, Ryan, Mychaleckyj, Josyf C, Nayak, Uma, Onengut-Gumuscu, Suna, Rich, Stephen S, Flannick, Jason A, Gaulton, Kyle J, Burtt, Noël P
Published in PLoS biology (10.08.2023)
Published in PLoS biology (10.08.2023)
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Journal Article
In situ 10-cell RNA sequencing in tissue and tumor biopsy samples
Singh, Shambhavi, Wang, Lixin, Schaff, Dylan L., Sutcliffe, Matthew D., Koeppel, Alex F., Kim, Jungeun, Onengut-Gumuscu, Suna, Park, Kwon-Sik, Zong, Hui, Janes, Kevin A.
Published in Scientific reports (20.03.2019)
Published in Scientific reports (20.03.2019)
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