Modulators of 14-3‑3 Protein–Protein Interactions
Stevers, Loes M, Sijbesma, Eline, Botta, Maurizio, MacKintosh, Carol, Obsil, Tomas, Landrieu, Isabelle, Cau, Ylenia, Wilson, Andrew J, Karawajczyk, Anna, Eickhoff, Jan, Davis, Jeremy, Hann, Michael, O’Mahony, Gavin, Doveston, Richard G, Brunsveld, Luc, Ottmann, Christian
Published in Journal of medicinal chemistry (10.05.2018)
Published in Journal of medicinal chemistry (10.05.2018)
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Journal Article
Adipose Tissue-Preserved Skin Graft: Applicability and Long-Term Results
Chung, Bryan, O'Mahony, Gavin D, Lam, Gretl, Chiu, David T W
Published in Plastic and reconstructive surgery (1963) (01.09.2017)
Published in Plastic and reconstructive surgery (1963) (01.09.2017)
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Journal Article
Stabilization of protein-protein interactions in drug discovery
Andrei, Sebastian A., Sijbesma, Eline, Hann, Michael, Davis, Jeremy, O'Mahony, Gavin, Perry, Matthew W. D., Karawajczyk, Anna, Eickhoff, Jan, Brunsveld, Luc, Doveston, Richard G., Milroy, Lech-Gustav, Ottmann, Christian
Published in Expert opinion on drug discovery (02.09.2017)
Published in Expert opinion on drug discovery (02.09.2017)
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Journal Article
Importance of thorough tissue and cellular level characterization of targeted drugs in the evaluation of pharmacodynamic effects
Bauknight, Dustin K, Osinski, Victoria, Dasa, Siva Sai Krishna, Nguyen, Anh T, Marshall, Melissa A, Hartman, Julia, Harms, Matthew, O'Mahony, Gavin, Boucher, Jeremie, Klibanov, Alexander L, McNamara, Coleen A, Kelly, Kimberly A
Published in PloS one (14.11.2019)
Published in PloS one (14.11.2019)
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Journal Article
N‑Biphenyl Pyrrolinones and Dibenzofurans as RNA-Binding Protein LIN28 Inhibitors Disrupting the LIN28–Let‑7 Interaction
Borgelt, Lydia, Hohnen, Lisa, Pallesen, Jakob S., Hommen, Pascal, Goebel, Georg L., Bosica, Francesco, Liu, Yang, O’Mahony, Gavin, Wu, Peng
Published in ACS medicinal chemistry letters (14.12.2023)
Published in ACS medicinal chemistry letters (14.12.2023)
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Journal Article
Designing Selective Drug-like Molecular Glues for the Glucocorticoid Receptor/14-3‑3 Protein–Protein Interaction
Pallesen, Jakob S., Munier, Claire C., Bosica, Francesco, Andrei, Sebastian A., Edman, Karl, Gunnarsson, Anders, La Sala, Giuseppina, Putra, Okky Dwichandra, Srdanović, Sonja, Wilson, Andrew J., Wissler, Lisa, Ottmann, Christian, Perry, Matthew W. D., O’Mahony, Gavin
Published in Journal of medicinal chemistry (22.12.2022)
Published in Journal of medicinal chemistry (22.12.2022)
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Journal Article
Correction to “Designing Selective Drug-like Molecular Glues for the Glucocorticoid Receptor/14-3‑3 Protein–Protein Interaction”
Pallesen, Jakob S., Munier, Claire C., Bosica, Francesco, Andrei, Sebastian A., Edman, Karl, Gunnarsson, Anders, La Sala, Giuseppina, Putra, Okky Dwichandra, Srdanović, Sonja, Wilson, Andrew J., Wissler, Lisa, Ottmann, Christian, Perry, Matthew W. D., O’Mahony, Gavin
Published in Journal of medicinal chemistry (09.02.2023)
Published in Journal of medicinal chemistry (09.02.2023)
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Journal Article
PPARγ and PPARα synergize to induce robust browning of white fat in vivo
Kroon, Tobias, Harms, Matthew, Maurer, Stefanie, Bonnet, Laurianne, Alexandersson, Ida, Lindblom, Anna, Ahnmark, Andrea, Nilsson, Daniel, Gennemark, Peter, O'Mahony, Gavin, Osinski, Victoria, McNamara, Coleen, Boucher, Jeremie
Published in Molecular metabolism (Germany) (01.06.2020)
Published in Molecular metabolism (Germany) (01.06.2020)
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Journal Article
Discovery by Virtual Screening of an Inhibitor of CDK5-Mediated PPARγ Phosphorylation
O’Mahony, Gavin, Petersen, Jens, Ek, Margareta, Rae, Rebecca, Johansson, Carina, Jianming, Liu, Prokoph, Nina, Bergström, Fredrik, Bamberg, Krister, Giordanetto, Fabrizio, Zarrouki, Bader, Karlsson, Daniel, Hogner, Anders
Published in ACS medicinal chemistry letters (14.04.2022)
Published in ACS medicinal chemistry letters (14.04.2022)
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Journal Article
Efficacy of Dorsoradial Capsulodesis for Trapeziometacarpal Joint Instability: A Cadaver Study
Chenoweth, Brian A., MD, O'Mahony, Gavin D., MD, Fitzgerald, Casey, BS, Stoner, Julie A., PhD, O'Donoghue, Daniel L., PhD, Rayan, Ghazi M., MD
Published in The Journal of hand surgery (American ed.) (2017)
Published in The Journal of hand surgery (American ed.) (2017)
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Journal Article
Identification of Mineralocorticoid Receptor Modulators with Low Impact on Electrolyte Homeostasis but Maintained Organ Protection
Granberg, Kenneth L, Yuan, Zhong-Qing, Lindmark, Bo, Edman, Karl, Kajanus, Johan, Hogner, Anders, Malmgren, Marcus, O’Mahony, Gavin, Nordqvist, Anneli, Lindberg, Jan, Tångefjord, Stefan, Kossenjans, Michael, Löfberg, Christian, Brånalt, Jonas, Liu, Dongmei, Selmi, Nidhal, Nikitidis, Grigorios, Nordberg, Peter, Hayen, Ahlke, Aagaard, Anna, Hansson, Eva, Hermansson, Majlis, Ivarsson, Ida, Jansson-Löfmark, Rasmus, Karlsson, Ulla, Johansson, Ulrika, William-Olsson, Lena, Hartleib-Geschwindner, Judith, Bamberg, Krister
Published in Journal of medicinal chemistry (14.02.2019)
Published in Journal of medicinal chemistry (14.02.2019)
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A luminescence-based protocol for assessing fructose metabolism via quantification of ketohexokinase enzymatic activity in mouse or human hepatocytes
Park, Se-Hyung, Helsley, Robert N., Noetzli, Leila, Tu, Ho-Chou, Wallenius, Kristina, O’Mahony, Gavin, Boucher, Jeremie, Liu, Jianming, Softic, Samir
Published in STAR protocols (17.09.2021)
Published in STAR protocols (17.09.2021)
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Journal Article
Discovery of 4-hydroxy-1,6-naphthyridine-3-carbonitrile derivatives as novel PDE10A inhibitors
Bauer, Udo, Giordanetto, Fabrizio, Bauer, Martin, O’Mahony, Gavin, Johansson, Kjell E., Knecht, Wolfgang, Hartleib-Geschwindner, Judith, Carlsson, Eva Töppner, Enroth, Cristofer
Published in Bioorganic & medicinal chemistry letters (01.03.2012)
Published in Bioorganic & medicinal chemistry letters (01.03.2012)
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Journal Article
In vivo liposomal delivery of PPARα/γ dual agonist tesaglitazar in a model of obesity enriches macrophage targeting and limits liver and kidney drug effects
Osinski, Victoria, Bauknight, Dustin K, Dasa, Siva Sai Krishna, Harms, Matthew J, Kroon, Tobias, Marshall, Melissa A, Garmey, James C, Nguyen, Anh T, Hartman, Julia, Upadhye, Aditi, Srikakulapu, Prasad, Zhou, Andrea, O'Mahony, Gavin, Klibanov, Alexander L, Kelly, Kimberly A, Boucher, Jeremie, McNamara, Coleen A
Published in Theranostics (2020)
Published in Theranostics (2020)
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Journal Article
Identification and design of a novel series of MGAT2 inhibitors
Barlind, Jonas G., Buckett, Linda K., Crosby, Sharon G., Davidsson, Öjvind, Emtenäs, Hans, Ertan, Anne, Jurva, Ulrik, Lemurell, Malin, Gutierrez, Pablo Morentin, Nilsson, Karolina, O’Mahony, Gavin, Petersson, Annika U., Redzic, Alma, Wågberg, Fredrik, Yuan, Zhong-Qing
Published in Bioorganic & medicinal chemistry letters (01.05.2013)
Published in Bioorganic & medicinal chemistry letters (01.05.2013)
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Journal Article
Chronic treatment with terbutaline increases glucose and oleic acid oxidation and protein synthesis in cultured human myotubes
Skagen, Christine, Nyman, Tuula A., Peng, Xiao-Rong, O'Mahony, Gavin, Kase, Eili Tranheim, Rustan, Arild Chr, Thoresen, G. Hege
Published in Current research in pharmacology and drug discovery (01.01.2021)
Published in Current research in pharmacology and drug discovery (01.01.2021)
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