Extending chemical perturbations of the ubiquitin fitness landscape in a classroom setting reveals new constraints on sequence tolerance
Mavor, David, Barlow, Kyle A, Asarnow, Daniel, Birman, Yuliya, Britain, Derek, Chen, Weilin, Green, Evan M, Kenner, Lillian R, Mensa, Bruk, Morinishi, Leanna S, Nelson, Charlotte A, Poss, Erin M, Suresh, Pooja, Tian, Ruilin, Arhar, Taylor, Ary, Beatrice E, Bauer, David P, Bergman, Ian D, Brunetti, Rachel M, Chio, Cynthia M, Dai, Shizhong A, Dickinson, Miles S, Elledge, Susanna K, Helsell, Cole V M, Hendel, Nathan L, Kang, Emily, Kern, Nadja, Khoroshkin, Matvei S, Kirkemo, Lisa L, Lewis, Greyson R, Lou, Kevin, Marin, Wesley M, Maxwell, Alison M, McTigue, Peter F, Myers-Turnbull, Douglas, Nagy, Tamas L, Natale, Andrew M, Oltion, Keely, Pourmal, Sergei, Reder, Gabriel K, Rettko, Nicholas J, Rohweder, Peter J, Schwarz, Daniel M C, Tan, Sophia K, Thomas, Paul V, Tibble, Ryan W, Town, Jason P, Tsai, Mary K, Ugur, Fatima S, Wassarman, Douglas R, Wolff, Alexander M, Wu, Taia S, Bogdanoff, Derek, Li, Jennifer, Thorn, Kurt S, O'Conchúir, Shane, Swaney, Danielle L, Chow, Eric D, Madhani, Hiten D, Redding, Sy, Bolon, Daniel N, Kortemme, Tanja, DeRisi, Joseph L, Kampmann, Martin, Fraser, James S
Published in Biology open (15.07.2018)
Published in Biology open (15.07.2018)
Get full text
Journal Article
An E3 ligase network engages GCN1 to promote the degradation of translation factors on stalled ribosomes
Oltion, Keely, Carelli, Jordan D., Yang, Tangpo, See, Stephanie K., Wang, Hao-Yuan, Kampmann, Martin, Taunton, Jack
Published in Cell (19.01.2023)
Published in Cell (19.01.2023)
Get full text
Journal Article
Differential scanning fluorimetry (DSF) screen to identify inhibitors of Hsp60 protein-protein interactions
Shao, Hao, Oltion, Keely, Wu, Taia, Gestwicki, Jason E
Published in Organic & biomolecular chemistry (10.06.2020)
Published in Organic & biomolecular chemistry (10.06.2020)
Get full text
Journal Article
The eRF1 degrader SRI-41315 acts as a molecular glue at the ribosomal decoding center
Coelho, João P. L., Yip, Matthew C. J., Oltion, Keely, Taunton, Jack, Shao, Sichen
Published in Nature chemical biology (01.07.2024)
Published in Nature chemical biology (01.07.2024)
Get full text
Journal Article
Synthesis and single-molecule imaging reveal stereospecific enhancement of binding kinetics by the antitumour eEF1A antagonist SR-A3
Wang, Hao-Yuan, Yang, Haojun, Holm, Mikael, Tom, Harrison, Oltion, Keely, Al-Khdhairawi, Amjad Ayad Qatran, Weber, Jean-Frédéric F., Blanchard, Scott C., Ruggero, Davide, Taunton, Jack
Published in Nature chemistry (01.12.2022)
Published in Nature chemistry (01.12.2022)
Get full text
Journal Article
ELONGATION FACTOR 1-ALPHA INHIBITORS AND USES THEREOF
OLTION, Keely, YANG, Haojun, TAUNTON, John, WANG, Haoyuan, RUGGERO, Davide
Year of Publication 29.05.2024
Get full text
Year of Publication 29.05.2024
Patent
ELONGATION FACTOR 1-ALPHA INHIBITORS AND USES THEREOF
Wang, Haoyuan, Yang, Haojun, Taunton, John, Ruggero, Davide, Oltion, Keely
Year of Publication 04.05.2023
Get full text
Year of Publication 04.05.2023
Patent
ELONGATION FACTOR 1-ALPHA INHIBITORS AND USES THEREOF
OLTION, Keely, YANG, Haojun, TAUNTON, John, WANG, Haoyuan, RUGGERO, Davide
Year of Publication 14.12.2022
Get full text
Year of Publication 14.12.2022
Patent
Elongation Factor 1-alpha inhibitors and uses thereof
OLTION, Keely, YANG, Haojun, TAUNTON, John, WANG, Haoyuan, RUGGERO, Davide
Year of Publication 25.08.2022
Get full text
Year of Publication 25.08.2022
Patent
ELONGATION FACTOR 1-ALPHA INHIBITORS AND USES THEREOF
OLTION, Keely, YANG, Haojun, TAUNTON, John, WANG, Haoyuan, RUGGERO, Davide
Year of Publication 12.08.2021
Get full text
Year of Publication 12.08.2021
Patent
ELONGATION FACTOR 1-ALPHA INHIBITORS AND USES THEREOF
WANG, HAOYUAN, TAUNTON, JOHN, OLTION, KEELY, RUGGERO, DAVIDE, YANG, HAOJUN
Year of Publication 12.08.2021
Get full text
Year of Publication 12.08.2021
Patent
Synthesis and single-molecule imaging reveal stereospecific enhancement of binding kinetics by the antitumor eEF1A antagonist SR-A3
Wang, Haoyuan, Yang, Haojun, Holm, Mikael, Oltion, Keely, Harrison, Tom, Amjad Ayad Qatran Al-Khdhairawi, Weber, Jean-Frederic F, Blanchard, Scott, Ruggero, Davide, Taunton, Jack
Published in bioRxiv (03.02.2022)
Published in bioRxiv (03.02.2022)
Get full text
Paper
Extending Chemical Perturbations Of The Ubiquitin Fitness Landscape In A Classroom Setting
Mavor, David, Barlow, Kyle, Asarnow, Daniel, Birman, Yuliya, Britain, Derek, Chen, Weilin, Green, Evan M, Kenner, Lillian R, Bruk Mensa, Morinishi, Leanna S, Nelson, Charlotte A, Poss, Erin M, Suresh, Pooja, Tian, Ruilin, Taylor Arhar, Ary, Beatrice E, Bauer, David P, Bergman, Ian D, Brunetti, Rachel M, Chio, Cynthia M, Dai, Shizhong A, Dickinson, Miles S, Elledge, Susanna, Hendel, Nathan L, Helsell, Cole V M, Kang, Emily, Kern, Nadja, Khoroshkin, Matvei S, Kirkemo, Lisa L, Lewis, Greyson R, Lou, Kevin, Marin, Wesley M, Maxwell, Alison M, Mctigue, Peter F, Meyers-Turnbull, Douglas, Nagy, Tamas L, Natale, Andrew M, Oltion, Keely, Pourmal, Sergei, Reder, Gabriel K, Rettko, Nicholas J, Rohweder, Peter J, Schwarz, Daniel M C, Tan, Sophia K, Thomas, Paul V, Tibble, Ryan W, Tsai, Mary K, Town, Jason P, Ugur, Fatima S, Wassarman, Douglas R, Wolff, Alexander M, Wu, Taia S, Bogdanoff, Derek, Li, Jennifer, Thorn, Kurt S, Shane Thomas O'conch ir, Swaney, Danielle L, Chow, Eric D, Madhani, Hiten D, Redding, Sy, Bolon, Daniel N A, Kortemme, Tanja, Derisi, Joseph L, Kampmann, Martin, Fraser, James S
Published in bioRxiv (17.05.2017)
Published in bioRxiv (17.05.2017)
Get full text
Paper