Tau prions from Alzheimer’s disease and chronic traumatic encephalopathy patients propagate in cultured cells
Woerman, Amanda L., Aoyagi, Atsushi, Patel, Smita, Kazmi, Sabeen A., Lobach, Iryna, Grinberg, Lea T., McKee, Ann C., Seeley, William W., Olson, Steven H., Prusiner, Stanley B.
Published in Proceedings of the National Academy of Sciences - PNAS (13.12.2016)
Published in Proceedings of the National Academy of Sciences - PNAS (13.12.2016)
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Multiple system atrophy prions retain strain specificity after serial propagation in two different Tg(SNCAA53T) mouse lines
Woerman, Amanda L., Oehler, Abby, Kazmi, Sabeen A., Lee, Jisoo, Halliday, Glenda M., Middleton, Lefkos T., Gentleman, Steve M., Mordes, Daniel A., Spina, Salvatore, Grinberg, Lea T., Olson, Steven H., Prusiner, Stanley B.
Published in Acta neuropathologica (01.03.2019)
Published in Acta neuropathologica (01.03.2019)
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The MDM2 Inhibitor AMG 232 Demonstrates Robust Antitumor Efficacy and Potentiates the Activity of p53-Inducing Cytotoxic Agents
Canon, Jude, Osgood, Tao, Olson, Steven H, Saiki, Anne Y, Robertson, Rebecca, Yu, Dongyin, Eksterowicz, John, Ye, Qiuping, Jin, Lixia, Chen, Ada, Zhou, Jing, Cordover, David, Kaufman, Stephen, Kendall, Richard, Oliner, Jonathan D, Coxon, Angela, Radinsky, Robert
Published in Molecular cancer therapeutics (01.03.2015)
Published in Molecular cancer therapeutics (01.03.2015)
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Selectivity in the Addition of Electron‐Deficient Radicals to the C2 Position of Indoles
Li, Yi, Vaz, Roy J., Olson, Steven H., Munson, Mark, Paras, Nick A., Conrad, Jay
Published in European journal of organic chemistry (30.09.2020)
Published in European journal of organic chemistry (30.09.2020)
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The E46K mutation modulates α-synuclein prion replication in transgenic mice
Holec, Sara A M, Lee, Jisoo, Oehler, Abby, Batia, Lyn, Wiggins-Gamble, Aryanna, Lau, Jeffrey, Ooi, Felicia K, Merz, Gregory E, Wang, Man, Mordes, Daniel A, Olson, Steven H, Woerman, Amanda L
Published in PLoS pathogens (01.12.2022)
Published in PLoS pathogens (01.12.2022)
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Familial Parkinson’s point mutation abolishes multiple system atrophy prion replication
Woerman, Amanda L., Kazmi, Sabeen A., Patel, Smita, Aoyagi, Atsushi, Oehler, Abby, Widjaja, Kartika, Mordes, Daniel A., Olson, Steven H., Prusiner, Stanley B.
Published in Proceedings of the National Academy of Sciences - PNAS (09.01.2018)
Published in Proceedings of the National Academy of Sciences - PNAS (09.01.2018)
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Water-Soluble Iridium Photoredox Catalyst for the Trifluoromethylation of Biomolecule Substrates in Phosphate Buffered Saline Solvent
Nguyen, Terrence-Thang H., O'Brien, Connor J., Tran, Minh L. N., Olson, Steven H., Settineri, Nicholas S., Prusiner, Stanley B., Paras, Nick A., Conrad, Jay
Published in Organic letters (21.05.2021)
Published in Organic letters (21.05.2021)
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A Selective Prostaglandin E2 Receptor Subtype 2 (EP2) Antagonist Increases the Macrophage-Mediated Clearance of Amyloid-Beta Plaques
Fox, Brian M, Beck, Hilary P, Roveto, Philip M, Kayser, Frank, Cheng, Qingwen, Dou, Hannah, Williamson, Toni, Treanor, James, Liu, Hantao, Jin, Lixia, Xu, Guifen, Ma, Ji, Wang, Songli, Olson, Steven H
Published in Journal of medicinal chemistry (09.07.2015)
Published in Journal of medicinal chemistry (09.07.2015)
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Structure-Based Design of Novel Inhibitors of the MDM2–p53 Interaction
Rew, Yosup, Sun, Daqing, Gonzalez-Lopez De Turiso, Felix, Bartberger, Michael D, Beck, Hilary P, Canon, Jude, Chen, Ada, Chow, David, Deignan, Jeffrey, Fox, Brian M, Gustin, Darin, Huang, Xin, Jiang, Min, Jiao, Xianyun, Jin, Lixia, Kayser, Frank, Kopecky, David J, Li, Yihong, Lo, Mei-Chu, Long, Alexander M, Michelsen, Klaus, Oliner, Jonathan D, Osgood, Tao, Ragains, Mark, Saiki, Anne Y, Schneider, Steve, Toteva, Maria, Yakowec, Peter, Yan, Xuelei, Ye, Qiuping, Yu, Dongyin, Zhao, Xiaoning, Zhou, Jing, Medina, Julio C, Olson, Steven H
Published in Journal of medicinal chemistry (14.06.2012)
Published in Journal of medicinal chemistry (14.06.2012)
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Inhibition of coronavirus HCoV-OC43 by targeting the eIF4F complex
Feng, Yongmei, Grotegut, Stefan, Jovanovic, Predrag, Gandin, Valentina, Olson, Steven H, Murad, Rabi, Beall, Anne, Colayco, Sharon, De-Jesus, Paul, Chanda, Sumit, English, Brian P, Singer, Robert H, Jackson, Michael, Topisirovic, Ivan, Ronai, Ze'ev A
Published in Frontiers in pharmacology (01.12.2022)
Published in Frontiers in pharmacology (01.12.2022)
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Developing Therapeutics for PrP Prion Diseases
Giles, Kurt, Olson, Steven H, Prusiner, Stanley B
Published in Cold Spring Harbor perspectives in medicine (01.04.2017)
Published in Cold Spring Harbor perspectives in medicine (01.04.2017)
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MSA prions exhibit remarkable stability and resistance to inactivation
Woerman, Amanda L., Kazmi, Sabeen A., Patel, Smita, Freyman, Yevgeniy, Oehler, Abby, Aoyagi, Atsushi, Mordes, Daniel A., Halliday, Glenda M., Middleton, Lefkos T., Gentleman, Steve M., Olson, Steven H., Prusiner, Stanley B.
Published in Acta neuropathologica (01.01.2018)
Published in Acta neuropathologica (01.01.2018)
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NRF2 mediates melanoma addiction to GCDH by modulating apoptotic signalling
Verma, Sachin, Crawford, David, Khateb, Ali, Feng, Yongmei, Sergienko, Eduard, Pathria, Gaurav, Ma, Chen-Ting, Olson, Steven H., Scott, David, Murad, Rabi, Ruppin, Eytan, Jackson, Michael, Ronai, Ze’ev A.
Published in Nature cell biology (01.09.2022)
Published in Nature cell biology (01.09.2022)
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Photoredox Cyanomethylation of Indoles: Catalyst Modification and Mechanism
O’Brien, Connor J, Droege, Daniel G, Jiu, Alexander Y, Gandhi, Shivaani S, Paras, Nick A, Olson, Steven H, Conrad, Jay
Published in Journal of organic chemistry (17.08.2018)
Published in Journal of organic chemistry (17.08.2018)
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Kinetics of Human Mutant Tau Prion Formation in the Brains of 2 Transgenic Mouse Lines
Woerman, Amanda L, Patel, Smita, Kazmi, Sabeen A, Oehler, Abby, Freyman, Yevgeniy, Espiritu, Lloyd, Cotter, Robert, Castaneda, Julian A, Olson, Steven H, Prusiner, Stanley B
Published in JAMA neurology (01.12.2017)
Published in JAMA neurology (01.12.2017)
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Discovery of AMG 232, a Potent, Selective, and Orally Bioavailable MDM2–p53 Inhibitor in Clinical Development
Sun, Daqing, Li, Zhihong, Rew, Yosup, Gribble, Michael, Bartberger, Michael D, Beck, Hilary P, Canon, Jude, Chen, Ada, Chen, Xiaoqi, Chow, David, Deignan, Jeffrey, Duquette, Jason, Eksterowicz, John, Fisher, Benjamin, Fox, Brian M, Fu, Jiasheng, Gonzalez, Ana Z, Gonzalez-Lopez De Turiso, Felix, Houze, Jonathan B, Huang, Xin, Jiang, Min, Jin, Lixia, Kayser, Frank, Liu, Jiwen (Jim), Lo, Mei-Chu, Long, Alexander M, Lucas, Brian, McGee, Lawrence R, McIntosh, Joel, Mihalic, Jeff, Oliner, Jonathan D, Osgood, Tao, Peterson, Matthew L, Roveto, Philip, Saiki, Anne Y, Shaffer, Paul, Toteva, Maria, Wang, Yingcai, Wang, Yu Chung, Wortman, Sarah, Yakowec, Peter, Yan, Xuelei, Ye, Qiuping, Yu, Dongyin, Yu, Ming, Zhao, Xiaoning, Zhou, Jing, Zhu, Jiang, Olson, Steven H, Medina, Julio C
Published in Journal of medicinal chemistry (27.02.2014)
Published in Journal of medicinal chemistry (27.02.2014)
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Multiple system atrophy prions transmit neurological disease to mice expressing wild-type human α-synuclein
Holec, Sara A. M., Lee, Jisoo, Oehler, Abby, Ooi, Felicia K., Mordes, Daniel A., Olson, Steven H., Prusiner, Stanley B., Woerman, Amanda L.
Published in Acta neuropathologica (01.10.2022)
Published in Acta neuropathologica (01.10.2022)
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Journal Article
Selectivity in the Addition of Electron Deficient Radicals to the C 2 Position of Indoles
Li, Yi, Vaz, Roy J, Olson, Steven H, Munson, Mark, Paras, Nick A, Conrad, Jay
Published in European journal of organic chemistry (30.09.2020)
Published in European journal of organic chemistry (30.09.2020)
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