Pharmacokinetic, Biodistribution, and Biophysical Profiles of TNF Nanobodies Conjugated to Linear or Branched Poly(ethylene glycol)
Vugmeyster, Yulia, Entrican, Clifford A, Joyce, Alison P, Lawrence-Henderson, Rosemary F, Leary, Beth A, Mahoney, Christopher S, Patel, Himakshi K, Raso, Stephen W, Olland, Stephane H, Hegen, Martin, Xu, Xin
Published in Bioconjugate chemistry (18.07.2012)
Published in Bioconjugate chemistry (18.07.2012)
Get full text
Journal Article
Improving the pharmacokinetic properties of biologics by fusion to an anti-HSA shark VNAR domain
Müller, Mischa R., Saunders, Kenneth, Grace, Christopher, Jin, Macy, Piche-Nicholas, Nicole, Steven, John, O'Dwyer, Ronan, Wu, Leeying, Khetemenee, Lam, Vugmeyster, Yulia, Hickling, Timothy P., Tchistiakova, Lioudmila, Olland, Stephane, Gill, Davinder, Jensen, Allan, Barelle, Caroline J.
Published in mAbs (01.11.2012)
Published in mAbs (01.11.2012)
Get full text
Journal Article
Crystal structures of the two major aggrecan degrading enzymes, ADAMTS4 and ADAMTS5
Mosyak, Lidia, Georgiadis, Katy, Shane, Tania, Svenson, Kristine, Hebert, Tracy, McDonagh, Thomas, Mackie, Stewart, Olland, Stephane, Lin, Laura, Zhong, Xiaotian, Kriz, Ronald, Reifenberg, Erica L., Collins‐Racie, Lisa A., Corcoran, Christopher, Freeman, Bethany, Zollner, Richard, Marvell, Tod, Vera, Matthew, Sum, Phaik‐Eng, Lavallie, Edward R., Stahl, Mark, Somers, William
Published in Protein science (01.01.2008)
Published in Protein science (01.01.2008)
Get full text
Journal Article
Interleukin-13 Neutralization by Two Distinct Receptor Blocking Mechanisms Reduces Immunoglobulin E Responses and Lung Inflammation in Cynomolgus Monkeys
Kasaian, Marion T, Tan, Xiang-Yang, Jin, Macy, Fitz, Lori, Marquette, Kimberly, Wood, Nancy, Cook, Timothy A, Lee, Julie, Widom, Angela, Agostinelli, Rita, Bree, Andrea, Schlerman, Franklin J, Olland, Stephane, Wadanoli, Michael, Sypek, Joseph, Gill, Davinder, Goldman, Samuel J, Tchistiakova, Lioudmila
Published in The Journal of pharmacology and experimental therapeutics (01.06.2008)
Published in The Journal of pharmacology and experimental therapeutics (01.06.2008)
Get full text
Journal Article
Oligomerization is required for the activity of recombinant soluble LOX-1
Cao, Wei, Calabro, Valerie, Root, Adam, Yan, Grace, Lam, Khetemenee, Olland, Stephane, Sanford, Jocelyn, Robak, Angela, Zollner, Richard, Lu, Zhijian, Ait-Zahra, Mostafa, Agostinelli, Rita, Tchistiakova, Lioudmila, Gill, Davinder, Harnish, Douglas, Paulsen, Janet, Shih, Heather H
Published in The FEBS journal (01.09.2009)
Published in The FEBS journal (01.09.2009)
Get full text
Journal Article
Two N-Terminal Domains of Kv4 K + Channels Regulate Binding to and Modulation by KChIP1
Scannevin, Robert H, Wang, KeWei, Jow, Flora, Megules, Jennifer, Kopsco, David C, Edris, Wade, Carroll, Karen C, Lü, Qiang, Xu, Weixin, Xu, Zhangbao, Katz, Alan H, Olland, Stephane, Lin, Laura, Taylor, Meggin, Stahl, Mark, Malakian, Karl, Somers, Will, Mosyak, Lydia, Bowlby, Mark R, Chanda, Pranab, Rhodes, Kenneth J
Published in Neuron (Cambridge, Mass.) (19.02.2004)
Published in Neuron (Cambridge, Mass.) (19.02.2004)
Get full text
Journal Article
Elongation of Synthetic RNA Templates by Hepatitis C Virus NS5B Polymerase
Liu, Cuihua, Chopra, Rajiv, Swanberg, Stephen, Olland, Stephane, O’Connell, John, Herrmann, Steve
Published in The Journal of biological chemistry (12.03.2004)
Published in The Journal of biological chemistry (12.03.2004)
Get full text
Journal Article
Development of PF-06671008, a Highly Potent Anti-P-cadherin/Anti-CD3 Bispecific DART Molecule with Extended Half-Life for the Treatment of Cancer
Root, Adam, Cao, Wei, Li, Bilian, LaPan, Peter, Meade, Caryl, Sanford, Jocelyn, Jin, Macy, O’Sullivan, Cliona, Cummins, Emma, Lambert, Matthew, Sheehan, Alfredo, Ma, Weijun, Gatto, Scott, Kerns, Kelvin, Lam, Khetemenee, D’Antona, Aaron, Zhu, Lily, Brady, William, Benard, Susan, King, Amy, He, Tao, Racie, Lisa, Arai, Maya, Barrett, Dianah, Stochaj, Wayne, LaVallie, Edward, Apgar, James, Svenson, Kristine, Mosyak, Lidia, Yang, Yinhua, Chichili, Gurunadh, Liu, Liqin, Li, Hua, Burke, Steve, Johnson, Syd, Alderson, Ralph, Finlay, William, Lin, Laura, Olland, Stéphane, Somers, William, Bonvini, Ezio, Gerber, Hans-Peter, May, Chad, Moore, Paul, Tchistiakova, Lioudmila, Bloom, Laird
Published in Antibodies (Basel) (04.03.2016)
Published in Antibodies (Basel) (04.03.2016)
Get full text
Journal Article
Catalytic Domain Crystal Structure of Protein Kinase C-θ (PKCθ)
Xu, Zhang-Bao, Chaudhary, Divya, Olland, Stephane, Wolfrom, Scott, Czerwinski, Robert, Malakian, Karl, Lin, Laura, Stahl, Mark L., Joseph-McCarthy, Diane, Benander, Christina, Fitz, Lori, Greco, Rita, Somers, William S., Mosyak, Lidia
Published in The Journal of biological chemistry (26.11.2004)
Published in The Journal of biological chemistry (26.11.2004)
Get full text
Journal Article
Primary sequence determination of a monoclonal antibody against α-synuclein using a novel mass spectrometry-based approach
Sousa, Eric, Olland, Stephane, Shih, Heather H., Marquette, Kim, Martone, Robert, Lu, Zhijian, Paulsen, Janet, Gill, Davinder, He, Tao
Published in International journal of mass spectrometry (15.02.2012)
Published in International journal of mass spectrometry (15.02.2012)
Get full text
Journal Article
CDR-restricted engineering of native human scFvs creates highly stable and soluble bifunctional antibodies for subcutaneous delivery
Fennell, Brian J, McDonnell, Barry, Tam, Amy Sze Pui, Chang, Lijun, Steven, John, Broadbent, Ian D, Gao, Huilan, Kieras, Elizabeth, Alley, Jennifer, Luxenberg, Deborah, Edmonds, Jason, Fitz, Lori J, Miao, Wenyan, Whitters, Matthew J, Medley, Quintus G, Guo, Yongjing J, Darmanin-Sheehan, Alfredo, Autin, Bénédicte, Shúilleabháin, Deirdre Ní, Cummins, Emma, King, Amy, Krebs, Mark RH, Grace, Christopher, Hickling, Timothy P, Boisvert, Angela, Zhong, Xiaotian, McKenna, Matthew, Francis, Christopher, Olland, Stephane, Bloom, Laird, Paulsen, Janet, Somers, Will, Jensen, Allan, Lin, Laura, Finlay, William JJ, Cunningham, Orla
Published in mAbs (01.11.2013)
Published in mAbs (01.11.2013)
Get full text
Journal Article
Distinct in vitro binding properties of the anti-CD20 small modular immunopharmaceutical 2LM20-4 result in profound and sustained in vivo potency in cynomolgus monkeys
NICKERSON-NUTTER, Cheryl, TCHISTIAKOVA, Lioudmila, WAHL, Alan, HERBER, Deborah, VUGMEYSTER, Yulia, WENSEL, David, WOLFMAN, Neil M, GILL, Davinder, COLLINS, Mary, DUNUSSI-JOANNOPOULOS, Kyri, SETH, Nilufer P, KASAIAN, Marion, SIBLEY, Barbara, OLLAND, Stephane, ZOLLNER, Richard, BRADY, William A, MOHLER, Kendall M, BAUM, Peter
Published in Rheumatology (Oxford, England) (01.06.2011)
Published in Rheumatology (Oxford, England) (01.06.2011)
Get full text
Journal Article
Characterization of Protein Kinase C θ Activation Loop Autophosphorylation and the Kinase Domain Catalytic Mechanism
Czerwinski, Robert, Aulabaugh, Ann, Greco, Rita M, Olland, Stephane, Malakian, Karl, Wolfrom, Scott, Lin, Laura, Kriz, Ron, Stahl, Mark, Huang, Ying, Liu, Lin, Chaudhary, Divya
Published in Biochemistry (Easton) (19.07.2005)
Published in Biochemistry (Easton) (19.07.2005)
Get full text
Journal Article
T.124. Mutation P331S in the Fc Domain of an Anti-CD20 SMIP™ Protein Confers Impaired in vivo B Cell Depletion Activity in Lymphoid Tissues of Cynomolgus Monkeys
Seth, Nilufer, Nickerson-Nutter, Cheryl, Medley, Quintus, Tchistiakova, Lioudmila, Olland, Stephane, Zollner, Richard, Brady, William, Mohler, Kendall, Baum, Peter, Wahl, Alan, Gill, Davinder, Collins, Mary
Published in Clinical immunology (Orlando, Fla.) (2009)
Published in Clinical immunology (Orlando, Fla.) (2009)
Get full text
Journal Article