From Triclosan toward the Clinic: Discovery of Nonbiocidal, Potent FabI Inhibitors for the Treatment of Resistant Bacteria
Gerusz, Vincent, Denis, Alexis, Faivre, Fabien, Bonvin, Yannick, Oxoby, Mayalen, Briet, Sophia, LeFralliec, Géraldine, Oliveira, Chrystelle, Desroy, Nicolas, Raymond, Cédric, Peltier, Laëtitia, Moreau, François, Escaich, Sonia, Vongsouthi, Vanida, Floquet, Stéphanie, Drocourt, Elodie, Walton, Armelle, Prouvensier, Laure, Saccomani, Marc, Durant, Lionel, Genevard, Jean-Marie, Sam-Sambo, Vanessa, Soulama-Mouze, Coralie
Published in Journal of medicinal chemistry (26.11.2012)
Published in Journal of medicinal chemistry (26.11.2012)
Get full text
Journal Article
Discovery of thiadiazoles as a novel structural class of potent and selective PDE7 inhibitors. Part 1: Design, synthesis and structure–activity relationship studies
Vergne, Fabrice, Bernardelli, Patrick, Lorthiois, Edwige, Pham, Nga, Proust, Emmanuelle, Oliveira, Chrystelle, Mafroud, Abdel-Kader, Royer, Frederique, Wrigglesworth, Roger, Schellhaas, Jennifer, Barvian, Mark, Moreau, François, Idrissi, Moulay, Tertre, Anita, Bertin, Bernadette, Coupe, Magali, Berna, Patrick, Soulard, Patricia
Published in Bioorganic & medicinal chemistry letters (20.09.2004)
Published in Bioorganic & medicinal chemistry letters (20.09.2004)
Get full text
Journal Article
Discovery of thiadiazoles as a novel structural class of potent and selective PDE7 inhibitors. Part 2: Metabolism-directed optimization studies towards orally bioavailable derivatives
Vergne, Fabrice, Bernardelli, Patrick, Lorthiois, Edwige, Pham, Nga, Proust, Emmanuelle, Oliveira, Chrystelle, Mafroud, Abdel-Kader, Ducrot, Pierre, Wrigglesworth, Roger, Berlioz-Seux, Françoise, Coleon, Francis, Chevalier, Eric, Moreau, François, Idrissi, Moulay, Tertre, Anita, Descours, Arnaud, Berna, Patrick, Li, Mei
Published in Bioorganic & medicinal chemistry letters (20.09.2004)
Published in Bioorganic & medicinal chemistry letters (20.09.2004)
Get full text
Journal Article
Novel HldE‑K Inhibitors Leading to Attenuated Gram Negative Bacterial Virulence
Desroy, Nicolas, Denis, Alexis, Oliveira, Chrystelle, Atamanyuk, Dmytro, Briet, Sophia, Faivre, Fabien, LeFralliec, Géraldine, Bonvin, Yannick, Oxoby, Mayalen, Escaich, Sonia, Floquet, Stéphanie, Drocourt, Elodie, Vongsouthi, Vanida, Durant, Lionel, Moreau, François, Verhey, Theodore B, Lee, Ting-Wai, Junop, Murray S, Gerusz, Vincent
Published in Journal of medicinal chemistry (28.02.2013)
Published in Journal of medicinal chemistry (28.02.2013)
Get full text
Journal Article
Structural–Functional Studies of Burkholderia cenocepacia d‑Glycero-β‑d‑manno-heptose 7‑Phosphate Kinase (HldA) and Characterization of Inhibitors with Antibiotic Adjuvant and Antivirulence Properties
Lee, Ting-Wai, Verhey, Theodore B, Antiperovitch, Pavel A, Atamanyuk, Dmytro, Desroy, Nicolas, Oliveira, Chrystelle, Denis, Alexis, Gerusz, Vincent, Drocourt, Elodie, Loutet, Slade A, Hamad, Mohamad A, Stanetty, Christian, Andres, Sara N, Sugiman-Marangos, Seiji, Kosma, Paul, Valvano, Miguel A, Moreau, Francois, Junop, Murray S
Published in Journal of medicinal chemistry (28.02.2013)
Published in Journal of medicinal chemistry (28.02.2013)
Get full text
Journal Article
새로운 헤테로사이클릭 화합물 및 이의 세균 감염 치료 또는 예방 용도
CHASSET SOPHIE, BARBION JULIEN, SIMON CHRISTOPHE, WAECKEL LUDOVIC, CHEVREUIL FRANCIS, LE STRAT FREDERIC, MOREAU FRANCOIS, CARAVANO AUDREY, LEDOUSSAL BENOIT, OLIVEIRA CHRYSTELLE, QUERNIN MARIE HELENE
Year of Publication 10.10.2019
Get full text
Year of Publication 10.10.2019
Patent
헤테로사이클릭 화합물 및 이의 박테리아 감염의 예방 또는 치료 용도
LECOINTE NICOLAS, SIMON CHRISTOPHE, CARAVANO AUDREY, VOMSCHEID SOPHIE, BRIAS JULIE, LEBEL REMI, CHASSET SOPHIE, BARBION JULIEN, FARESCOUR LAURENCE, CHEVREUIL FRANCIS, LE STRAT FREDERIC, LE FRALLIEC GERALDINE, LEDOUSSAL BENOIT, OLIVEIRA CHRYSTELLE, RICHARD SEBASTIEN, FAIVRE FABIEN
Year of Publication 11.06.2019
Get full text
Year of Publication 11.06.2019
Patent
Structural-Functional Studies of Burkholderia cenocepaciad-Glycero- beta -d-manno-heptose 7-Phosphate Kinase (HldA) and Characterization of Inhibitors with Antibiotic Adjuvant and Antivirulence Properties
Lee, Ting-Wai, Verhey, Theodore B, Antiperovitch, Pavel A, Atamanyuk, Dmytro, Desroy, Nicolas, Oliveira, Chrystelle, Denis, Alexis, Gerusz, Vincent, Drocourt, Elodie, Loutet, Slade A, Hamad, Mohamad A, Stanetty, Christian, Andres, Sara N, Sugiman-Marangos, Seiji, Kosma, Paul, Valvano, Miguel A, Moreau, Francois, Junop, Murray S
Published in Journal of medicinal chemistry (20.12.2012)
Published in Journal of medicinal chemistry (20.12.2012)
Get full text
Journal Article
헤테로사이클릭 화합물 및 세균성 감염을 예방 또는 치료하는 이의 용도
LECOINTE NICOLAS, SIMON CHRISTOPHE, BRIET SOPHIA, CARAVANO AUDREY, VOMSCHEID SOPHIE, BRIAS JULIE, CHASSET SOPHIE, BARBION JULIEN, CHEVREUIL FRANCIS, LE STRAT FREDERIC, LE FRALLIEC GERALDINE, LEDOUSSAL BENOIT, OLIVEIRA CHRYSTELLE, RICHARD SEBASTIEN, FAIVRE FABIEN
Year of Publication 08.01.2018
Get full text
Year of Publication 08.01.2018
Patent
Spiroquinazolinones as novel, potent, and selective PDE7 inhibitors. Part 1
Lorthiois, Edwige, Bernardelli, Patrick, Vergne, Fabrice, Oliveira, Chrystelle, Mafroud, Abdel-Kader, Proust, Emmanuelle, Heuze, Lamia, Moreau, François, Idrissi, Moulay, Tertre, Anita, Bertin, Bernadette, Coupe, Magali, Wrigglesworth, Roger, Descours, Arnaud, Soulard, Patricia, Berna, Patrick
Published in Bioorganic & medicinal chemistry letters (20.09.2004)
Published in Bioorganic & medicinal chemistry letters (20.09.2004)
Get full text
Journal Article
Spiroquinazolinones as novel, potent, and selective PDE7 inhibitors. Part 2: Optimization of 5,8-disubstituted derivatives
Bernardelli, Patrick, Lorthiois, Edwige, Vergne, Fabrice, Oliveira, Chrystelle, Mafroud, Abdel-Kader, Proust, Emmanuelle, Pham, Nga, Ducrot, Pierre, Moreau, François, Idrissi, Moulay, Tertre, Anita, Bertin, Bernadette, Coupe, Magali, Chevalier, Eric, Descours, Arnaud, Berlioz-Seux, Françoise, Berna, Patrick, Li, Mei
Published in Bioorganic & medicinal chemistry letters (20.09.2004)
Published in Bioorganic & medicinal chemistry letters (20.09.2004)
Get full text
Journal Article
HETEROCYCLIC COMPOUNDS AND THEIR USE IN PREVENTING OR TREATING BACTERIAL INFECTIONS
CHASSET, Sophie, FARESCOUR, Laurence, LE-STRAT, Frederic, BRIAS, Julie, BARBION, Julien, OLIVEIRA, Chrystelle, RICHARD, Sebastien, LE FRALLIEC, Geraldine, CHEVREUIL, Francis, VOMSCHEID, Sophie, CARAVANO, Audrey, SIMON, Christophe, FAIVRE, Fabien, LEBEL, Remi, LEDOUSSAL, Benoît, LECOINTE, Nicolas
Year of Publication 28.01.2023
Get full text
Year of Publication 28.01.2023
Patent
HETEROCYCLIC COMPOUNDS AND THEIR USE IN PREVENTING OR TREATING BACTERIAL INFECTIONS
CHASSET, Sophie, FARESCOUR, Laurence, BRIAS, Julie, BARBION, Julien, OLIVEIRA, Chrystelle, CHEVREUIL, Francis, VOMSCHEID, Sophie, CARAVANO, Audrey, LEBEL, Rémi, LE FRALLIEC, Géraldine, SIMON, Christophe, FAIVRE, Fabien, LEDOUSSAL, Benoît, LE-STRAT, Frédéric, RICHARD, Sébastien, LECOINTE, Nicolas
Year of Publication 09.11.2022
Get full text
Year of Publication 09.11.2022
Patent
HETEROCYCLIC COMPOUNDS AND THEIR USE IN PREVENTING OR TREATING BACTERIAL INFECTIONS
Farescour, Laurence, Caravano, Audrey, Lebel, Rémi, Richard, Sébastien, Brias, Julie, Vomscheid, Sophie, Le-strat, Frédéric, Ledoussal, Benoît, Chevreuil, Francis, Faivre, Fabien, Chasset, Sophie, Lecointe, Nicolas, Simon, Christophe, Oliveira, Chrystelle, Barbion, Julien, Le Fralliec, Géraldine
Year of Publication 30.09.2022
Get full text
Year of Publication 30.09.2022
Patent
HETEROCYCLIC COMPOUNDS AND THEIR USE IN PREVENTING OR TREATING BACTERIAL INFECTIONS
CHASSET, Sophie, FARESCOUR, Laurence, BRIAS, Julie, BARBION, Julien, OLIVEIRA, Chrystelle, CHEVREUIL, Francis, VOMSCHEID, Sophie, CARAVANO, Audrey, LEBEL, Rémi, LE FRALLIEC, Géraldine, SIMON, Christophe, FAIVRE, Fabien, LEDOUSSAL, Benoît, LE-STRAT, Frédéric, RICHARD, Sébastien, LECOINTE, Nicolas
Year of Publication 12.09.2022
Get full text
Year of Publication 12.09.2022
Patent
HETEROCYCLIC COMPOUNDS AND THEIR USE IN PREVENTING OR TREATING BACTERIAL INFECTIONS
FAIVRE, FABIEN, LE-STRAT, FRÉDÉRIC, LECOINTE, NICOLAS, LEDOUSSAL, BENOÎT, CHEVREUIL, FRANCIS, OLIVEIRA, CHRYSTELLE, CHASSET, SOPHIE, LEBEL, RÉMI, FARESCOUR, LAURENCE, CARAVANO, AUDREY, BARBION, JULIEN, RICHARD, SÉBASTIEN, BRIAS, JULIE, LE FRALLIEC, GÉRALDINE, VOMSCHEID, SOPHIE, SIMON, CHRISTOPHE
Year of Publication 31.08.2022
Get full text
Year of Publication 31.08.2022
Patent