The Rationale for the Dual-Targeting Therapy for RSK2 and AKT in Multiple Myeloma
Isa, Reiko, Horinaka, Mano, Tsukamoto, Taku, Mizuhara, Kentaro, Fujibayashi, Yuto, Taminishi-Katsuragawa, Yoko, Okamoto, Haruya, Yasuda, Shusuke, Kawaji-Kanayama, Yuka, Matsumura-Kimoto, Yayoi, Mizutani, Shinsuke, Shimura, Yuji, Taniwaki, Masafumi, Sakai, Toshiyuki, Kuroda, Junya
Published in International journal of molecular sciences (08.03.2022)
Published in International journal of molecular sciences (08.03.2022)
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Journal Article
Durable Remission of Chemotherapy-Refractory Myeloid Sarcoma by Azacitidine
Okamoto, Haruya, Kamitsuji, Yuri, Komori, Yukiko, Sasaki, Nana, Tsutsumi, Yasuhiko, Miyashita, Akihiro, Tsukamoto, Taku, Mizutani, Shinsuke, Shimura, Yuji, Kobayashi, Tsutomu, Uoshima, Nobuhiko, Kuroda, Junya
Published in The Tohoku Journal of Experimental Medicine (2021)
Published in The Tohoku Journal of Experimental Medicine (2021)
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Journal Article
Good's Syndrome With Pure Red Cell Aplasia and Subclinical Myasthenia Gravis: A Case Report and Review of Literature
Hashiro, Wakana, Miyashita, Akihiro, Kawaji-Kanayama, Yuka, Okamoto, Haruya, Fujino, Takahiro, Tsukamoto, Taku, Mizutani, Shinsuke, Shimura, Yuji, Kuroda, Junya
Published in Curēus (Palo Alto, CA) (04.05.2024)
Published in Curēus (Palo Alto, CA) (04.05.2024)
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Journal Article
Paroxysmal nocturnal hemoglobinuria complicated with essential thrombocythemia harboring concomitant PIGA, CALR, and ASXL1 mutations
Okamoto, Haruya, Uoshima, Nobuhiko, Kamitsuji, Yuri, Kawata, Eri, Komori, Yukiko, Sasaki, Nana, Tsutsumi, Yasuhiko, Tsukamoto, Taku, Mizutani, Shinsuke, Nannya, Yasuhito, Kuroda, Junya
Published in Annals of hematology (01.08.2021)
Published in Annals of hematology (01.08.2021)
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Journal Article
Small cell pattern of ALK‐negative anaplastic large cell lymphoma with double‐hit rearrangements of DUSP22 and TP63
Niiyama‐Uchibori, Yui, Mizutani, Shinsuke, Tsukamoto, Taku, Okamoto, Haruya, Ide, Daisuke, Onishi, Akio, Kato, Daishi, Fujino, Takahiro, Shimira, Yuji, Miyagawa‐Hayashino, Aya, Konishi, Eiichi, Karube, Kennosuke, Nannya, Yasuhito, Kuroda, Junya
Published in EJHaem (01.08.2024)
Published in EJHaem (01.08.2024)
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Journal Article
Combination of Bone Marrow Biopsy and Flow Cytometric Analysis: The Prognostically Relevant Central Approach for Detecting Bone Marrow Invasion in Diffuse Large B-Cell Lymphoma
Okamoto, Haruya, Uoshima, Nobuhiko, Muramatsu, Ayako, Isa, Reiko, Fujino, Takahiro, Matsumura-Kimoto, Yayoi, Tsukamoto, Taku, Mizutani, Shinsuke, Shimura, Yuji, Kobayashi, Tsutomu, Kawata, Eri, Uchiyama, Hitoji, Kuroda, Junya
Published in Diagnostics (Basel) (20.09.2021)
Published in Diagnostics (Basel) (20.09.2021)
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Journal Article
Mir-106a-5p and Mir-146a-5p Delivered By Tumor-Derived Exosomes Promote the Induction of Myeloid-Derived Suppressor Cells from Normal Peripheral Blood Mononuclear Cells in Multiple Myeloma
Mizuhara, Kentaro, Shimura, Yuji, Tsukamoto, Taku, Kanai, Akinori, Kuwahara-Ota, Saeko, Yamaguchi, Junko, Muramatsu, Ayako, Okamoto, Haruya, Katsuragawa-Taminishi, Yoko, Kawaji-Kanayama, Yuka, Isa, Reiko, Mizutani, Shinsuke, Inaba, Toshiya, Kuroda, Junya
Published in Blood (15.11.2022)
Published in Blood (15.11.2022)
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Journal Article
Robust anti-myeloma effect of TAS0612, an RSK/AKT/S6K inhibitor, with venetoclax regardless of cytogenetic abnormalities
Okamoto, Haruya, Mizutani, Shinsuke, Tsukamoto, Taku, Katsuragawa-Taminishi, Yoko, Kawaji-Kanayama, Yuka, Mizuhara, Kentaro, Muramatsu, Ayako, Isa, Reiko, Fujino, Takahiro, Shimura, Yuji, Ichikawa, Koji, Kuroda, Junya
Published in Leukemia (22.10.2024)
Published in Leukemia (22.10.2024)
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Journal Article
TAS0612, a Triple Inhibitor for RSK, AKT, and S6K, Is a Promising Anti-Myeloma Agent Regardless of Types of Cytogenetic/Genetic Abnormality
Okamoto, Haruya, Mizutani, Shinsuke, Tsukamoto, Taku, Katsuragawa-Taminishi, Yoko, Isa, Reiko, Mizuhara, Kentaro, Muramatsu, Ayako, Kawaji-Kanayama, Yuka, Fujino, Takahiro, Shimura, Yuji, Kuroda, Junya
Published in Blood (02.11.2023)
Published in Blood (02.11.2023)
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Journal Article
Interim Serum Soluble Interleukin-2 Receptor Levels Are Strongly Associated with Prognosis in Newly Diagnosis DLBCL Patients
Okamoto, Haruya, Miyashita, Akihiro, Nagata, Hiroaki, Tsutsumi, Yasuhiko, Kamitsuji, Yuri, Kobayashi, Yutaka, Uoshima, Nobuhiko
Published in Blood (13.11.2019)
Published in Blood (13.11.2019)
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Journal Article
The Universal Antitumor Activity of TAS0612, a Triple Inhibitor for RSK, AKT, and S6K, in B-Cell Lymphomas Regardless of Disease Subtype
Katsuragawa-Taminishi, Yoko, Mizutani, Shinsuke, Kawaji-Kanayama, Yuka, Onishi, Akio, Okamoto, Haruya, Isa, Reiko, Mizuhara, Kentaro, Muramatsu, Ayako, Fujino, Takahiro, Tsukamoto, Taku, Shimura, Yuji, Taniwaki, Masafumi, Miyagawa-Hayashino, Aya, Konishi, Eiichi, Kuroda, Junya
Published in Blood (02.11.2023)
Published in Blood (02.11.2023)
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Journal Article
The Activation Status of RSK2, but Not PDPK1 and AKT, Associates with the Prognosis of Diffuse Large B Cell Lymphoma
Onishi, Akio, Miyagawa-Hayashino, Aya, Mizuhara, Kentaro, Muramatsu, Ayako, Okamoto, Haruya, Kawaji-Kanayama, Yuka, Katsuragawa-Taminishi, Yoko, Fujino, Takahiro, Tsukamoto, Taku, Mizutani, Shinsuke, Shimura, Yuji, Konishi, Eiichi, Kuroda, Junya
Published in Blood (02.11.2023)
Published in Blood (02.11.2023)
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Journal Article
A case of neuroleukemiosis: The usefulness of nerve ultrasound as a diagnostic tool
Kitaoji, Takamasa, Noto, Yu‐ichi, Kasai, Takashi, Mizuhara, Kentaro, Okamoto, Haruya, Tsukamoto, Taku, Kuroda, Junya, Mizuno, Toshiki
Published in Muscle & nerve (01.05.2022)
Published in Muscle & nerve (01.05.2022)
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Journal Article
Nutritional and Cytogenetic Assessment Predicts Favorable Response to Azacitidine Monotherapy for Myelodysplastic Syndromes
Okamoto, Haruya, Inoue, Yu, Miyashita, Akihiro, Kawaji-Kanayama, Yuka, Chinen, Shotaro, Fujino, Takahiro, Tsukamoto, Taku, Shimura, Yuji, Mizutani, Shinsuke, Kaneko, Hiroto, Kuwahara, Saeko, Fuchida, Shin-ichi, Nishiyama, Daichi, Hirakawa, Koichi, Kuroda, Junya
Published in Blood (15.11.2022)
Published in Blood (15.11.2022)
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Journal Article
Tumour‐derived exosomes promote the induction of monocytic myeloid‐derived suppressor cells from peripheral blood mononuclear cells by delivering miR ‐106a‐5p and miR ‐146a‐5p in multiple myeloma
Mizuhara, Kentaro, Shimura, Yuji, Tsukamoto, Taku, Kanai, Akinori, Kuwahara‐Ota, Saeko, Yamaguchi, Junko, Muramatsu, Ayako, Okamoto, Haruya, Taminishi‐Katsuragawa, Yoko, Kawaji‐Kanayama, Yuka, Isa, Reiko, Mizutani, Shinsuke, Inaba, Toshiya, Kuroda, Junya
Published in British journal of haematology (01.11.2023)
Published in British journal of haematology (01.11.2023)
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Journal Article
Triple targeting of RSK, AKT, and S6K as pivotal downstream effectors of PDPK1 by TAS0612 in B‐cell lymphomas
Katsuragawa‐Taminishi, Yoko, Mizutani, Shinsuke, Kawaji‐Kanayama, Yuka, Onishi, Akio, Okamoto, Haruya, Isa, Reiko, Mizuhara, Kentaro, Muramatsu, Ayako, Fujino, Takahiro, Tsukamoto, Taku, Shimura, Yuji, Taniwaki, Masafumi, Miyagawa‐Hayashino, Aya, Konishi, Eiichi, Kuroda, Junya
Published in Cancer science (01.12.2023)
Published in Cancer science (01.12.2023)
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Journal Article
Skeletal muscle index impacts the treatment outcome of elderly patients with diffuse large B cell lymphoma
Niiyama‐Uchibori, Yui, Okamoto, Haruya, Miyashita, Akihiro, Mizuhara, Kentaro, Kanayama‐Kawaji, Yuka, Fujino, Takahiro, Tsukamoto, Taku, Mizutani, Shinsuke, Shimura, Yuji, Teramukai, Satoshi, Kuroda, Junya
Published in Hematological oncology (01.01.2024)
Published in Hematological oncology (01.01.2024)
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Journal Article
Real-world practice-based prognostic model for higher-risk myelodysplastic syndromes treated with azacitidine monotherapy: The Kyoto prognostic scoring system
Okamoto, Haruya, Inoue, Yu, Miyashita, Akihiro, Kawaji-Kanayama, Yuka, Chinen, Shotaro, Fujino, Takahiro, Tsukamoto, Taku, Shimura, Yuji, Mizutani, Shinsuke, Kaneko, Hiroto, Kuwahara-Ota, Saeko, Fuchida, Shin-ichi, Nishiyama, Daichi, Hirakawa, Koichi, Uchiyama, Hitoji, Uoshima, Nobuhiko, Kawata, Eri, Kuroda, Junya
Published in International journal of hematology (01.09.2023)
Published in International journal of hematology (01.09.2023)
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Journal Article
Clinical impacts of severe thrombocytopenia in the first cycle of azacitidine monotherapy and cytogenetics in patients with myelodysplastic syndrome: The Kyoto Conditional Survival Scoring System
Inoue, Yu, Okamoto, Haruya, Miyashita, Akihiro, Kawaji-Kanayama, Yuka, Chinen, Shotaro, Fujino, Takahiro, Tsukamoto, Taku, Shimura, Yuji, Mizutani, Shinsuke, Kaneko, Hiroto, Kuwahara-Ota, Saeko, Fuchida, Shin-Ichi, Nishiyama, Daichi, Hirakawa, Koichi, Uchiyama, Hitoji, Uoshima, Nobuhiko, Kawata, Eri, Kuroda, Junya
Published in Oncology letters (01.02.2024)
Published in Oncology letters (01.02.2024)
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Journal Article
Clinical Implication of the Effect of the Production of Neutralizing Antibodies Against SARS-Cov-2 for Chronic Immune Thrombocytopenia Flare-Up Associated with COVID-19 Infection: A Case Report and the Review of Literature
Maekura, Chika, Muramatsu, Ayako, Nagata, Hiroaki, Okamoto, Haruya, Onishi, Akio, Kato, Daishi, Isa, Reiko, Fujino, Takahiro, Tsukamoto, Taku, Mizutani, Shinsuke, Shimura, Yuji, Kobayashi, Tsutomu, Okumura, Keita, Inaba, Tohru, Nukui, Yoko, Kuroda, Junya
Published in Infection and drug resistance (31.05.2022)
Published in Infection and drug resistance (31.05.2022)
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Journal Article