Antidepressant-like behavior in brain-specific angiogenesis inhibitor 2-deficient mice
Okajima, Daisuke, Kudo, Gen, Yokota, Hiroshi
Published in The journal of physiological sciences (01.01.2011)
Published in The journal of physiological sciences (01.01.2011)
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Journal Article
Datopotamab Deruxtecan, a Novel TROP2-directed Antibody-drug Conjugate, Demonstrates Potent Antitumor Activity by Efficient Drug Delivery to Tumor Cells
Okajima, Daisuke, Yasuda, Satoru, Maejima, Takanori, Karibe, Tsuyoshi, Sakurai, Ken, Aida, Tetsuo, Toki, Tadashi, Yamaguchi, Junko, Kitamura, Michiko, Kamei, Reiko, Fujitani, Tomomichi, Honda, Tomoyo, Shibutani, Tomoko, Muramatsu, Sumie, Nakada, Takashi, Goto, Riki, Takahashi, Shu, Yamaguchi, Miki, Hamada, Hirofumi, Noguchi, Yutaka, Murakami, Masato, Abe, Yuki, Agatsuma, Toshinori
Published in Molecular cancer therapeutics (01.12.2021)
Published in Molecular cancer therapeutics (01.12.2021)
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Journal Article
Abstract A027: Combination of TROP2 and SLFN11 as the sensitivity biomarkers for DS-1062a, a novel TROP2-targeting antibody-drug conjugate with a novel DNA topoisomerase I inhibitor DXd
Yasuda, Satoru, Okajima, Daisuke, Toki, Tadashi, Yamaguchi, Junko, Karibe, Tsuyoshi, Fujitani, Tomomichi, Nakada, Takashi, Noguchi, Yutaka, Murakami, Masato
Published in Molecular cancer therapeutics (01.12.2019)
Published in Molecular cancer therapeutics (01.12.2019)
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Journal Article
Abstract 4893: Evaluation of bystander antitumor effect of Dato-DXd in TROP2 (+) and TROP2 (-) lung cell lines admixed tumor xenograft mouse models
Yasuda, Satoru, Maejima, Takanori, Toki, Tadashi, Karibe, Tsuyoshi, Okajima, Daisuke, Phillips, Penny
Published in Cancer research (Chicago, Ill.) (04.04.2023)
Published in Cancer research (Chicago, Ill.) (04.04.2023)
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Journal Article
Antidepressant-like behavior in brain-specific angiogenesis inhibitor 2-deficient mice
Okajima, Daisuke, Kudo, Gen, Yokota, Hiroshi
Published in The journal of physiological sciences (01.01.2011)
Published in The journal of physiological sciences (01.01.2011)
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Journal Article
ANTI-TROP2 ANTIBODY-DRUG CONJUGATE
HAMADA HIROFUMI, AZUMA TOSHINORI, YAMAGUCHI MIKI, OKAJIMA DAISUKE, TAKAHASHI HIDE, HASEGAWA JUN
Year of Publication 20.06.2023
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Year of Publication 20.06.2023
Patent
TROP2 - ANTI-TROP2 ANTIBODY-DRUG CONJUGATE
HAMADA HIROFUMI, TAKAHASHI SHU, YAMAGUCHI MIKI, OKAJIMA DAISUKE, AGATSUMA TOSHINORI, HASEGAWA JUN
Year of Publication 02.06.2023
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Year of Publication 02.06.2023
Patent
Abstract 2932: Datopotamab deruxtecan (Dato-DXd) enhances antitumor response to PD-1/PD-L1 inhibitors in TROP2-expressing tumors in mice
Okajima, Daisuke, Yasuda, Satoru, Suzuki, Takami, Kitamura, Michiko, Yamaguchi, Junko, Maejima, Takanori, Karibe, Tsuyoshi, Toki, Tadashi, Phillips, Penny, Agatsuma, Toshinori
Published in Cancer research (Chicago, Ill.) (04.04.2023)
Published in Cancer research (Chicago, Ill.) (04.04.2023)
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Journal Article
Abstract C026: DS-1062a, a novel TROP2-targeting antibody-drug conjugate with a novel DNA topoisomerase I inhibitor DXd, demonstrates potent antitumor activity in preclinical models
Okajima, Daisuke, Yamaguchi, Junko, Kitamura, Michiko, Kamei, Reiko, Maejima, Takanori, Shibutani, Tomoko, Yasuda, Satoru, Toki, Tadashi, Karibe, Tsuyoshi, Fujitani, Tomomichi, Nakada, Takashi, Goto, Riki, Noguchi, Yutaka, Abe, Yuki, Agatsuma, Toshinori
Published in Molecular cancer therapeutics (01.12.2019)
Published in Molecular cancer therapeutics (01.12.2019)
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Journal Article
TROP2 - ANTI-TROP2 ANTIBODY-DRUG CONJUGATE
HAMADA HIROFUMI, TAKAHASHI SHU, YAMAGUCHI MIKI, OKAJIMA DAISUKE, AGATSUMA TOSHINORI, HASEGAWA JUN
Year of Publication 07.02.2023
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Year of Publication 07.02.2023
Patent
First-in-human phase 1 study of DS-1062a in patients with advanced solid tumors
Sands, Jacob M., Shimizu, Toshio, Garon, Edward B., Greenberg, Jonathan, Guevara, Ferdinand M., Heist, Rebecca Suk, Kobayashi, Fumiaki, Noguchi, Yutaka, Okajima, Daisuke, Tajima, Naoyuki, Spira, Alexander I., Yamamoto, Noboru, Lisberg, Aaron Elliott
Published in Journal of clinical oncology (20.05.2019)
Published in Journal of clinical oncology (20.05.2019)
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Journal Article
TROP2 - ANTI-TROP2 ANTIBODY-DRUG CONJUGATE
HAMADA HIROFUMI, TAKAHASHI SHU, YAMAGUCHI MIKI, OKAJIMA DAISUKE, AGATSUMA TOSHINORI, HASEGAWA JUN
Year of Publication 29.09.2022
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Year of Publication 29.09.2022
Patent