Genome-wide analysis of DNA methylation dynamics during early human development
Okae, Hiroaki, Chiba, Hatsune, Hiura, Hitoshi, Hamada, Hirotaka, Sato, Akiko, Utsunomiya, Takafumi, Kikuchi, Hiroyuki, Yoshida, Hiroaki, Tanaka, Atsushi, Suyama, Mikita, Arima, Takahiro
Published in PLoS genetics (01.12.2014)
Published in PLoS genetics (01.12.2014)
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Trophoblast stem cell-based organoid models of the human placental barrier
Hori, Takeshi, Okae, Hiroaki, Shibata, Shun, Kobayashi, Norio, Kobayashi, Eri H., Oike, Akira, Sekiya, Asato, Arima, Takahiro, Kaji, Hirokazu
Published in Nature communications (08.02.2024)
Published in Nature communications (08.02.2024)
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The multifaceted role of GCM1 during trophoblast differentiation in the human placenta
Jeyarajah, Mariyan J, Jaju Bhattad, Gargi, Kelly, Rachel D, Baines, Kelly J, Jaremek, Adam, Yang, Fei-Hung P, Okae, Hiroaki, Arima, Takahiro, Dumeaux, Vanessa, Renaud, Stephen J
Published in Proceedings of the National Academy of Sciences - PNAS (06.12.2022)
Published in Proceedings of the National Academy of Sciences - PNAS (06.12.2022)
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Induction of Human Trophoblast Stem Cells from Somatic Cells and Pluripotent Stem Cells
Castel, Gaël, Meistermann, Dimitri, Bretin, Betty, Firmin, Julie, Blin, Justine, Loubersac, Sophie, Bruneau, Alexandre, Chevolleau, Simon, Kilens, Stéphanie, Chariau, Caroline, Gaignerie, Anne, Francheteau, Quentin, Kagawa, Harunobu, Charpentier, Eric, Flippe, Léa, François--Campion, Valentin, Haider, Sandra, Dietrich, Bianca, Knöfler, Martin, Arima, Takahiro, Bourdon, Jérémie, Rivron, Nicolas, Masson, Damien, Fournier, Thierry, Okae, Hiroaki, Fréour, Thomas, David, Laurent
Published in Cell reports (Cambridge) (24.11.2020)
Published in Cell reports (Cambridge) (24.11.2020)
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Regulation of human trophoblast gene expression by endogenous retroviruses
Frost, Jennifer M., Amante, Samuele M., Okae, Hiroaki, Jones, Eleri M., Ashley, Brogan, Lewis, Rohan M., Cleal, Jane K., Caley, Matthew P., Arima, Takahiro, Maffucci, Tania, Branco, Miguel R.
Published in Nature structural & molecular biology (01.04.2023)
Published in Nature structural & molecular biology (01.04.2023)
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Allele-Specific Methylome and Transcriptome Analysis Reveals Widespread Imprinting in the Human Placenta
Hamada, Hirotaka, Okae, Hiroaki, Toh, Hidehiro, Chiba, Hatsune, Hiura, Hitoshi, Shirane, Kenjiro, Sato, Tetsuya, Suyama, Mikita, Yaegashi, Nobuo, Sasaki, Hiroyuki, Arima, Takahiro
Published in American journal of human genetics (03.11.2016)
Published in American journal of human genetics (03.11.2016)
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Epigenetic dynamics of partially methylated domains in human placenta and trophoblast stem cells
Toh, Hidehiro, Okae, Hiroaki, Shirane, Kenjiro, Sato, Tetsuya, Hamada, Hirotaka, Kikutake, Chie, Saito, Daisuke, Arima, Takahiro, Sasaki, Hiroyuki, Suyama, Mikita
Published in BMC genomics (06.11.2024)
Published in BMC genomics (06.11.2024)
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The microRNA cluster C19MC confers differentiation potential into trophoblast lineages upon human pluripotent stem cells
Kobayashi, Norio, Okae, Hiroaki, Hiura, Hitoshi, Kubota, Naoto, Kobayashi, Eri H., Shibata, Shun, Oike, Akira, Hori, Takeshi, Kikutake, Chie, Hamada, Hirotaka, Kaji, Hirokazu, Suyama, Mikita, Bortolin-Cavaillé, Marie-Line, Cavaillé, Jérôme, Arima, Takahiro
Published in Nature communications (02.06.2022)
Published in Nature communications (02.06.2022)
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Abnormal cleavage is involved in the self-correction of bovine preimplantation embryos
Nagai, Hiroki, Okada, Mai, Nagai, Yoko, Sakuraba, Yoshiyuki, Okae, Hiroaki, Suzuki, Ryosuke, Sugimura, Satoshi
Published in Biochemical and biophysical research communications (12.07.2021)
Published in Biochemical and biophysical research communications (12.07.2021)
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Association of four imprinting disorders and ART
Hattori, Hiromitsu, Hiura, Hitoshi, Kitamura, Akane, Miyauchi, Naoko, Kobayashi, Norio, Takahashi, Souta, Okae, Hiroaki, Kyono, Koichi, Kagami, Masayo, Ogata, Tsutomu, Arima, Takahiro
Published in Clinical epigenetics (07.02.2019)
Published in Clinical epigenetics (07.02.2019)
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Histone deacetylase 1 and 2 drive differentiation and fusion of progenitor cells in human placental trophoblasts
Jaju Bhattad, Gargi, Jeyarajah, Mariyan J., McGill, Megan G., Dumeaux, Vanessa, Okae, Hiroaki, Arima, Takahiro, Lajoie, Patrick, Bérubé, Nathalie G., Renaud, Stephen J.
Published in Cell death & disease (04.05.2020)
Published in Cell death & disease (04.05.2020)
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ASCL2 reciprocally controls key trophoblast lineage decisions during hemochorial placenta development
Varberg, Kaela M., Iqbal, Khursheed, Muto, Masanaga, Simon, Mikaela E., Scott, Regan L., Kozai, Keisuke, Choudhury, Ruhul H., Aplin, John D., Biswell, Rebecca, Gibson, Margaret, Okae, Hiroaki, Arima, Takahiro, Vivian, Jay L., Grundberg, Elin, Soares, Michael J.
Published in Proceedings of the National Academy of Sciences - PNAS (09.03.2021)
Published in Proceedings of the National Academy of Sciences - PNAS (09.03.2021)
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CITED2 is a conserved regulator of the uterine-placental interface
Kuna, Marija, Dhakal, Pramod, Iqbal, Khursheed, Dominguez, Esteban M, Kent, Lindsey N, Muto, Masanaga, Moreno-Irusta, Ayelen, Kozai, Keisuke, Varberg, Kaela M, Okae, Hiroaki, Arima, Takahiro, Sucov, Henry M, Soares, Michael J
Published in Proceedings of the National Academy of Sciences - PNAS (17.01.2023)
Published in Proceedings of the National Academy of Sciences - PNAS (17.01.2023)
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Lactate dehydrogenase C is required for the protein expression of a sperm-specific isoform of lactate dehydrogenase A
Dodo, Mina, Kitamura, Hiroshi, Shima, Hiroki, Saigusa, Daisuke, Wati, Sisca Meida, Ota, Nao, Katsuoka, Fumiki, Chiba, Hatsune, Okae, Hiroaki, Arima, Takahiro, Igarashi, Kazuhiko, Koseki, Takeyoshi, Sekine, Hiroki, Motohashi, Hozumi
Published in Journal of biochemistry (Tokyo) (01.04.2019)
Published in Journal of biochemistry (Tokyo) (01.04.2019)
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Highly rigid H3.1/H3.2-H3K9me3 domains set a barrier for cell fate reprogramming in trophoblast stem cells
Hada, Masashi, Miura, Hisashi, Tanigawa, Akie, Matoba, Shogo, Inoue, Kimiko, Ogonuki, Narumi, Hirose, Michiko, Watanabe, Naomi, Nakato, Ryuichiro, Fujiki, Katsunori, Hasegawa, Ayumi, Sakashita, Akihiko, Okae, Hiroaki, Miura, Kento, Shikata, Daiki, Arima, Takahiro, Shirahige, Katsuhiko, Hiratani, Ichiro, Ogura, Atsuo
Published in Genes & development (01.01.2022)
Published in Genes & development (01.01.2022)
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Extravillous trophoblast cell lineage development is associated with active remodeling of the chromatin landscape
Varberg, Kaela M., Dominguez, Esteban M., Koseva, Boryana, Varberg, Joseph M., McNally, Ross P., Moreno-Irusta, Ayelen, Wesley, Emily R., Iqbal, Khursheed, Cheung, Warren A., Schwendinger-Schreck, Carl, Smail, Craig, Okae, Hiroaki, Arima, Takahiro, Lydic, Michael, Holoch, Kristin, Marsh, Courtney, Soares, Michael J., Grundberg, Elin
Published in Nature communications (10.08.2023)
Published in Nature communications (10.08.2023)
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G protein subunit β1 is an important mediator of the late stage of endochondral ossification
Ruengsinpinya, Lerdluck, Murakami, Tomohiko, Nakamura, Eriko, Takahata, Yoshifumi, Hata, Kenji, Nakaminami, Yuri, Okae, Hiroaki, Nishimura, Riko
Published in Biochemical and biophysical research communications (26.11.2020)
Published in Biochemical and biophysical research communications (26.11.2020)
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Atypical protein kinase C iota (PKCλ/ι) ensures mammalian development by establishing the maternal–fetal exchange interface
Bhattacharya, Bhaswati, Home, Pratik, Ganguly, Avishek, Ray, Soma, Ghosh, Ananya, Islam, Md. Rashedul, French, Valerie, Marsh, Courtney, Gunewardena, Sumedha, Okae, Hiroaki, Arima, Takahiro, Paul, Soumen
Published in Proceedings of the National Academy of Sciences - PNAS (23.06.2020)
Published in Proceedings of the National Academy of Sciences - PNAS (23.06.2020)
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Intersection of regulatory pathways controlling hemostasis and hemochorial placentation
Muto, Masanaga, Chakraborty, Damayanti, Varberg, Kaela M., Moreno-Irusta, Ayelen, Iqbal, Khursheed, Scott, Regan L., McNally, Ross P., Choudhury, Ruhul H., Aplin, John D., Okae, Hiroaki, Arima, Takahiro, Matsumoto, Shoma, Ema, Masatsugu, Mast, Alan E., Grundberg, Elin, Soares, Michael J.
Published in Proceedings of the National Academy of Sciences - PNAS (14.12.2021)
Published in Proceedings of the National Academy of Sciences - PNAS (14.12.2021)
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