Convergent Solid-Phase Synthesis of Macromolecular MUC1 Models Truly Mimicking Serum Glycoprotein Biomarkers of Interstitial Lung Diseases
Ohyabu, Naoki, Kakiya, Kiyoshi, Yokoi, Yasuhiro, Hinou, Hiroshi, Nishimura, Shin-Ichiro
Published in Journal of the American Chemical Society (13.07.2016)
Published in Journal of the American Chemical Society (13.07.2016)
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Journal Article
Site-Specific Conformational Alteration Induced by Sialylation of MUC1 Tandem Repeating Glycopeptides at an Epitope Region for the Anti-KL‑6 Monoclonal Antibody
Matsushita, Takahiko, Ohyabu, Naoki, Fujitani, Naoki, Naruchi, Kentaro, Shimizu, Hiroki, Hinou, Hiroshi, Nishimura, Shin-Ichiro
Published in Biochemistry (Easton) (15.01.2013)
Published in Biochemistry (Easton) (15.01.2013)
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Journal Article
An Essential Epitope of Anti-MUC1 Monoclonal Antibody KL-6 Revealed by Focused Glycopeptide Library
Ohyabu, Naoki, Hinou, Hiroshi, Matsushita, Takahiko, Izumi, Ryukou, Shimizu, Hiroki, Kawamoto, Keiko, Numata, Yoshito, Togame, Hiroko, Takemoto, Hiroshi, Kondo, Hirosato, Nishimura, Shin-Ichiro
Published in Journal of the American Chemical Society (02.12.2009)
Published in Journal of the American Chemical Society (02.12.2009)
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Journal Article
An Efficient Approach for the Characterization of Mucin-Type Glycopeptides: The Effect of O-Glycosylation on the Conformation of Synthetic Mucin Peptides
Hashimoto, Ryo, Fujitani, Naoki, Takegawa, Yasuhiro, Kurogochi, Masaki, Matsushita, Takahiko, Naruchi, Kentaro, Ohyabu, Naoki, Hinou, Hiroshi, Gao, Xiao Dong, Manri, Naomi, Satake, Hiroyuki, Kaneko, Akihito, Sakamoto, Takeshi, Nishimura, Shin-Ichiro
Published in Chemistry : a European journal (18.02.2011)
Published in Chemistry : a European journal (18.02.2011)
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Journal Article
Generation of Novel Anti-MUC1 Monoclonal Antibodies with Designed Carbohydrate Specificities Using MUC1 Glycopeptide Library
Naito, Shoichi, Takahashi, Tatsuya, Onoda, Junji, Uemura, Shoko, Ohyabu, Naoki, Takemoto, Hiroshi, Yamane, Shoji, Fujii, Ikuo, Nishimura, Shin-Ichiro, Numata, Yoshito
Published in ACS omega (30.11.2017)
Published in ACS omega (30.11.2017)
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Journal Article
Functional Neoglycopeptides: Synthesis and Characterization of a New Class of MUC1 Glycoprotein Models Having Core 2-Based O-Glycan and Complex-Type N-Glycan Chains
Matsushita, Takahiko, Sadamoto, Reiko, Ohyabu, Naoki, Nakata, Hideki, Fumoto, Masataka, Fujitani, Naoki, Takegawa, Yasuhiro, Sakamoto, Takeshi, Kurogochi, Masaki, Hinou, Hiroshi, Shimizu, Hiroki, Ito, Takaomi, Naruchi, Kentarou, Togame, Hiroko, Takemoto, Hiroshi, Kondo, Hirosato, Nishimura, Shin-Ichiro
Published in Biochemistry (Easton) (24.11.2009)
Published in Biochemistry (Easton) (24.11.2009)
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Journal Article
In-crystal chemical ligation for lead compound generation
Yamane, Junji, Ohyabu, Naoki, Yao, Min, Takemoto, Hiroshi, Tanaka, Isao
Published in Journal of applied crystallography (01.12.2010)
Published in Journal of applied crystallography (01.12.2010)
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Journal Article
WED-216 - TLC-3595, a selective acetyl-CoA carboxylase 2 (ACC2) inhibitor, improves steatosis and fibrosis in murine models of NASH via pleiotropic mechanisms
Vijayakumar, Archana, Murakami, Eisuke, Huss, Ryan, Sroda, Natalie, Shimazaki, Atsuyuki, Morita, Ippei, Kato, Hideaki, Nakai, Manami, Ohyabu, Naoki, Subramanian, Mani, Myers, Robert
Published in Journal of hepatology (01.06.2023)
Published in Journal of hepatology (01.06.2023)
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Journal Article
TLC-3595, a selective acetyl-CoA carboxylase 2 (ACC2) inhibitor, improves steatosis and fibrosis in murine models of NASH via pleiotropic mechanisms
Vijayakumar, Archana, Murakami, Eisuke, Huss, Ryan, Sroda, Natalie, Shimazaki, Atsuyuki, Morita, Ippei, Kato, Hideaki, Nakai, Manami, Ohyabu, Naoki, Subramanian, Mani, Myers, Robert
Published in Journal of hepatology (01.06.2023)
Published in Journal of hepatology (01.06.2023)
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Journal Article
Interaction of Arenastatin A with Porcine Brain Tubulin
MORITA, Koji, KOISO, Yukiko, HASHIMOTO, Yuichi, KOBAYASHI, Motomasa, WANG, Weiqi, OHYABU, Naoki, IWASAKI, Shigeo
Published in Biological & pharmaceutical bulletin (01.02.1997)
Published in Biological & pharmaceutical bulletin (01.02.1997)
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Journal Article
THE ABSOLUTE STEREOSTRUCTURE OF ARENASTATIN A, A POTENT CYTOTOXIC DEPSIPEPTIDE FROM THE OKINAWAN MARINE SPONGE DYSIDEA ARENARIA
KOBAYASHI, Motomasa, KUROSU, Michio, OHYABU, Naoki, WANG, Weiqi, FUJII, Satoshi, KITAGAWA, Isao
Published in Chemical & pharmaceutical bulletin (1994)
Published in Chemical & pharmaceutical bulletin (1994)
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Journal Article
SPIRO HETEROCYCLIC DERIVATIVE HAVING MGAT2-INHIBITING ACTIVITY
OHYABU, Naoki, KATOU, Manabu, TATENO, Yusuke, IWATSU, Masafumi, NISHIURA, Yuji
Year of Publication 27.04.2017
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Year of Publication 27.04.2017
Patent
9원 축합환 유도체
OHYABU NAOKI, MIYAZAKI KEISUKE, SASAKI YOSHIKAZU, WADA TOSHIHIRO, KATOU MANABU, KURAHASHI KANA, NISHIURA YUJI, IWATSU MASAFUMI
Year of Publication 29.11.2017
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Year of Publication 29.11.2017
Patent
Characterization of novel non-peptide thrombopoietin mimetics, their species specificity and the activation mechanism of the thrombopoietin receptor
Yamane, Noriko, Tanaka, Yoshikazu, Ohyabu, Naoki, Yamane, Shoji, Maekawa, Kazuhiko, Ishizaki, Jun, Suzuki, Ryuji, Itoh, Tsunetoshi, Takemoto, Hiroshi
Published in European journal of pharmacology (31.05.2008)
Published in European journal of pharmacology (31.05.2008)
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Journal Article
9-MEMBERED FUSED RING DERIVATIVE
OHYABU, Naoki, SASAKI, Yoshikazu, KATOU, Manabu, MIYAZAKI, Keisuke, IWATSU, Masafumi, KURAHASHI, Kana, NISHIURA, Yuji, WADA, Toshihiro
Year of Publication 06.10.2016
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Year of Publication 06.10.2016
Patent
NOVEL NON-AROMATIC CARBOCYCLIC OR NON-AROMATIC HETEROCYCLIC DERIVATIVE
MASUDA, KOJI, IWATSU, MASAFUMI, OHYABU, NAOKI, SASAKI, YOSHIKAZU, MATSUMURA, AKIRA, ASAHI, KENTARO
Year of Publication 24.04.2014
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Year of Publication 24.04.2014
Patent
AZABENZIMIDAZOLE DERIVATIVE HAVING AMPK-ACTIVATING ACTIVITY
FUJIOKA MASAHIKO, OHYABU NAOKI, KOJIMA EIICHI, TANAKA NOBUYUKI, TONOGAKI KEISUKE, KATOU MANABU, HINATA YU, INO AKIRA, IWATSU MASAFUMI
Year of Publication 03.04.2014
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Year of Publication 03.04.2014
Patent