Orally active lysophosphatidic acid receptor antagonist attenuates pancreatic cancer invasion and metastasis in vivo
Komachi, Mayumi, Sato, Koichi, Tobo, Masayuki, Mogi, Chihiro, Yamada, Takayuki, Ohta, Hideo, Tomura, Hideaki, Kimura, Takao, Im, Dong‐Soon, Yanagida, Keisuke, Ishii, Satoshi, Takeyoshi, Izumi, Okajima, Fumikazu
Published in Cancer science (01.06.2012)
Published in Cancer science (01.06.2012)
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Ki16425, a Subtype-Selective Antagonist for EDG-Family Lysophosphatidic Acid Receptors
Ohta, Hideo, Sato, Koichi, Murata, Naoya, Damirin, Alatangaole, Malchinkhuu, Enkhzol, Kon, Junko, Kimura, Takao, Tobo, Masayuki, Yamazaki, Yuji, Watanabe, Tomoko, Yagi, Mikio, Sato, Motoko, Suzuki, Rika, Murooka, Hideko, Sakai, Teruyuki, Nishitoba, Tsuyoshi, Im, Dong-Soon, Nochi, Hiromi, Tamoto, Koichi, Tomura, Hideaki, Okajima, Fumikazu
Published in Molecular pharmacology (01.10.2003)
Published in Molecular pharmacology (01.10.2003)
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Lysophosphatidic Acid (LPA) in Malignant Ascites Stimulates Motility of Human Pancreatic Cancer Cells through LPA1
Yamada, Takayuki, Sato, Koichi, Komachi, Mayumi, Malchinkhuu, Enkhzol, Tobo, Masayuki, Kimura, Takao, Kuwabara, Atsushi, Yanagita, Yasuhiro, Ikeya, Toshiro, Tanahashi, Yoshifumi, Ogawa, Tetsushi, Ohwada, Susumu, Morishita, Yasuo, Ohta, Hideo, Im, Doon-Soon, Tamoto, Koichi, Tomura, Hideaki, Okajima, Fumikazu
Published in The Journal of biological chemistry (20.02.2004)
Published in The Journal of biological chemistry (20.02.2004)
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Sphingosine 1-phosphate stimulates proliferation and migration of human endothelial cells possibly through the lipid receptors, Edg-1 and Edg-3
Kimura, T, Watanabe, T, Sato, K, Kon, J, Tomura, H, Tamama, K, Kuwabara, A, Kanda, T, Kobayashi, I, Ohta, H, Ui, M, Okajima, F
Published in Biochemical journal (15.05.2000)
Published in Biochemical journal (15.05.2000)
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Role of lipoprotein-associated lysophospholipids in migratory activity of coronary artery smooth muscle cells
Damirin, Alatangaole, Tomura, Hideaki, Komachi, Mayumi, Liu, Jin-Peng, Mogi, Chihiro, Tobo, Masayuki, Wang, Ju-Qiang, Kimura, Takao, Kuwabara, Atsushi, Yamazaki, Yuji, Ohta, Hideo, Im, Doon-Soon, Sato, Koichi, Okajima, Fumikazu
Published in American journal of physiology. Heart and circulatory physiology (01.05.2007)
Published in American journal of physiology. Heart and circulatory physiology (01.05.2007)
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Comparison of Intrinsic Activities of the Putative Sphingosine 1-Phosphate Receptor Subtypes to Regulate Several Signaling Pathways in Their cDNA-transfected Chinese Hamster Ovary Cells
Kon, Junko, Sato, Koichi, Watanabe, Tomoko, Tomura, Hideaki, Kuwabara, Atsushi, Kimura, Takao, Tamama, Ken-ichi, Ishizuka, Tamotsu, Murata, Naoya, Kanda, Tsugiyasu, Kobayashi, Isao, Ohta, Hideo, Ui, Michio, Okajima, Fumikazu
Published in The Journal of biological chemistry (20.08.1999)
Published in The Journal of biological chemistry (20.08.1999)
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p2y5/LPA6 attenuates LPA1-mediated VE-cadherin translocation and cell-cell dissociation through G12/13 protein-Src-Rap1
Kimura, Takao, Mogi, Chihiro, Sato, Koichi, Tomura, Hideaki, Ohta, Hideo, Im, Doon-Soon, Kuwabara, Atsushi, Kurose, Hitoshi, Murakami, Masami, Okajima, Fumikazu
Published in Cardiovascular research (01.10.2011)
Published in Cardiovascular research (01.10.2011)
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Edg-6 as a Putative Sphingosine 1-Phosphate Receptor Coupling to Ca2+ Signaling Pathway
Yamazaki, Yuji, Kon, Junko, Sato, Koichi, Tomura, Hideaki, Sato, Motoko, Yoneya, Takashi, Okazaki, Hiroshi, Okajima, Fumikazu, Ohta, Hideo
Published in Biochemical and biophysical research communications (16.02.2000)
Published in Biochemical and biophysical research communications (16.02.2000)
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Dual mode regulation of migration by lysophosphatidic acid in human gastric cancer cells
Shida, Dai, Kitayama, Joji, Yamaguchi, Hironori, Hama, Kotaro, Aoki, Junken, Arai, Hiroyuki, Yamashita, Hiroharu, Mori, Ken, Sako, Akihiro, Konishi, Tsuyoshi, Watanabe, Toshiaki, Sakai, Teruyuki, Suzuki, Rika, Ohta, Hideo, Takuwa, Yoh, Nagawa, Hirokazu
Published in Experimental cell research (10.12.2004)
Published in Experimental cell research (10.12.2004)
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LPA 1 receptors mediate stimulation, whereas LPA 2 receptors mediate inhibition, of migration of pancreatic cancer cells in response to lysophosphatidic acid and malignant ascites
Komachi, Mayumi, Tomura, Hideaki, Malchinkhuu, Enkhzol, Tobo, Masayuki, Mogi, Chihiro, Yamada, Takayuki, Kimura, Takao, Kuwabara, Atsushi, Ohta, Hideo, Im, Doon-Soon, Kurose, Hitoshi, Takeyoshi, Izumi, Sato, Koichi, Okajima, Fumikazu
Published in Carcinogenesis (New York) (01.03.2009)
Published in Carcinogenesis (New York) (01.03.2009)
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Lysophosphatidic Acid (LPA)-Induced Vascular Endothelial Growth Factor (VEGF) by Mesothelial Cells and Quantification of Host-Derived VEGF in Malignant Ascites
Sako, Akihiro, Kitayama, Joji, Shida, Dai, Suzuki, Rika, Sakai, Teruyuki, Ohta, Hideo, Nagawa, Hirokazu
Published in The Journal of surgical research (2006)
Published in The Journal of surgical research (2006)
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Lysophosphatidic Acid and Autotaxin Stimulate Cell Motility of Neoplastic and Non-neoplastic Cells through LPA1
Hama, Kotaro, Aoki, Junken, Fukaya, Masahiro, Kishi, Yasuhiro, Sakai, Teruyuki, Suzuki, Rika, Ohta, Hideo, Yamori, Takao, Watanabe, Masahiko, Chun, Jerold, Arai, Hiroyuki
Published in The Journal of biological chemistry (23.04.2004)
Published in The Journal of biological chemistry (23.04.2004)
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Downregulation of mRNA Expression of Edg-3, a Putative Sphingosine 1-Phosphate Receptor Coupled to Ca2+Signaling, during Differentiation of HL-60 Leukemia Cells
Sato, Koichi, Murata, Naoya, Kon, Junko, Tomura, Hideaki, Nochi, Hiromi, Tamoto, Koichi, Osada, Mizuho, Ohta, Hideo, Tokumitsu, Yukiko, Ui, Michio, Okajima, Fumikazu
Published in Biochemical and biophysical research communications (18.12.1998)
Published in Biochemical and biophysical research communications (18.12.1998)
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A case of metachronous splenic metastasis from gastric cancer
Sasakawa, Hirokazu, Okada, Kazuyuki, Maruyama, Kentarou, Ohta, Hideo, Ide, Yoshito, Murata, Kouhei, Yokouchi, Hideoki, Kinuta, Masakatsu
Published in Gan to kagaku ryoho (01.11.2008)
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Published in Gan to kagaku ryoho (01.11.2008)
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A case of multiple liver metastases from rectal cancer in poor performance status successfully treated with hepatic arterial infusion chemotherapy plus CPT-11
Ide, Yoshihito, Okada, Kazuyuki, Ohta, Hideo, Maruyama, Kentaro, Yokouchi, Hideoki, Kinuta, Masakatsu, Yasumoto, Taku, Murata, Kohei
Published in Gan to kagaku ryoho (01.11.2007)
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Published in Gan to kagaku ryoho (01.11.2007)
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Sphingosine 1-phosphate stimulates proliferation and migration of human endothelial cells possibly through the lipid receptors, Edg-1 and Edg-3
KIMURA, Takao, WATANABE, Tomoko, SATO, Koichi, KON, Junko, TOMURA, Hideaki, TAMAMA, Ken-ichi, KUWABARA, Atsushi, KANDA, Tsugiyasu, KOBAYASHI, Isao, OHTA, Hideo, UI, Michio, OKAJIMA, Fumikazu
Published in Biochemical journal (15.05.2000)
Published in Biochemical journal (15.05.2000)
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Cardioprotective effects of KRN2391 and nicorandil on ischemic dysfunction in perfused rat heart
Ohta, H, Jinno, Y, Harada, K, Ogawa, N, Fukushima, H, Nishikori, K
Published in European journal of pharmacology (05.11.1991)
Published in European journal of pharmacology (05.11.1991)
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Multiple inflammatory pseudotumors mimicking liver metastasis from colon cancer: report of a case
Ishida, H, Tatsuta, M, Furukawa, H, Ohta, H, Hashimoto, K, Hayashi, N, Morimoto, O, Ikeda, M, Miya, A, Masutani, S, Kawasaki, T, Satomi, T, Yoshioka, H, Hanai, J
Published in Surgery today (Tokyo, Japan) (01.01.2000)
Published in Surgery today (Tokyo, Japan) (01.01.2000)
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Stimulatory Role of Lysophosphatidic Acid in Cyclooxygenase-2 Induction by Synovial Fluid of Patients with Rheumatoid Arthritis in Fibroblast-Like Synovial Cells
Nochi, Hiromi, Tomura, Hideaki, Tobo, Masayuki, Tanaka, Nobuyuki, Sato, Koichi, Shinozaki, Tetsuya, Kobayashi, Tsutomu, Takagishi, Kenji, Ohta, Hideo, Okajima, Fumikazu, Tamoto, Koichi
Published in The Journal of immunology (1950) (01.10.2008)
Published in The Journal of immunology (1950) (01.10.2008)
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Effects of the K+ channel opener KRN4884 on the cardiovascular metabolic syndrome model in rats
Okada, Y, Yoshino, T, Takeuchi, A, Endoh, M, Ohta, H, Jinno, Y, Yokoyama, T, Izawa, T, Kobayshi, E
Published in Journal of cardiovascular pharmacology (01.02.2000)
Published in Journal of cardiovascular pharmacology (01.02.2000)
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