Development and SAR of functionally selective allosteric modulators of GABAA receptors
Alhambra, Cristobal, Becker, Chris, Blake, Timothy, Chang, Amy (Hui-Fang), Damewood, James R., Jr, Daniels, Thalia, Dembofsky, Bruce T, Gurley, David A, Hall, James E, Herzog, Keith J, Horchler, Carey L, Ohnmacht, Cyrus J, Schmiesing, Richard Jon, Dudley, Adam, Ribadeneira, Maria D, Knappenberger, Katherine S, Maciag, Carla, Stein, Mark M, Chopra, Maninder, Liu, Xiaodong F, Christian, Edward P, Arriza, Jeffrey L, Chapdelaine, Marc J
Published in Bioorganic & medicinal chemistry (01.05.2011)
Published in Bioorganic & medicinal chemistry (01.05.2011)
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Design, Synthesis, and SAR of Tachykinin Antagonists: Modulation of Balance in NK1/NK2 Receptor Antagonist Activity
Albert, Jeffrey S, Aharony, David, Andisik, Donald, Barthlow, Herbert, Bernstein, Peter R, Bialecki, Russell A, Dedinas, Robert, Dembofsky, Bruce T, Hill, Daniel, Kirkland, Karin, Koether, Gerard M, Kosmider, Benedict J, Ohnmacht, Cyrus, Palmer, William, Potts, William, Rumsey, William, Shen, Lihong, Shenvi, Ashok, Sherwood, Scott, Warwick, Paul J, Russell, Keith
Published in Journal of medicinal chemistry (29.08.2002)
Published in Journal of medicinal chemistry (29.08.2002)
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Naphtho[2,1-b][1,5] and [1,2-f][1,4]oxazocines as selective NK1 antagonists
OHNMACHT, Cyrus J, ALBERT, Jeffrey S, BERNSTEIN, Peter R, RUMSEY, William L, MASEK, Brian B, DEMBOFSKY, Bruce T, KOETHER, Gerard M, ANDISIK, Donald W, AHARONY, David
Published in Bioorganic & medicinal chemistry (15.05.2004)
Published in Bioorganic & medicinal chemistry (15.05.2004)
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Structural Analysis and Optimization of NK1 Receptor Antagonists through Modulation of Atropisomer Interconversion Properties
Albert, Jeffrey S, Ohnmacht, Cyrus, Bernstein, Peter R, Rumsey, William L, Aharony, David, Alelyunas, Yun, Russell, Daniel J, Potts, William, Sherwood, Scott A, Shen, Lihong, Dedinas, Robert F, Palmer, William E, Russell, Keith
Published in Journal of medicinal chemistry (29.01.2004)
Published in Journal of medicinal chemistry (29.01.2004)
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Synthesis of single-enantiomer 6-hydroxy-7-phenyl-1,4-oxazepan-5-ones
Becker, CW, Dembofsky, BT, Hall, JE, Jacobs, RT, Pivonka, DE, Ohnmacht, CJ
Published in Synthesis (Stuttgart) (04.10.2005)
Published in Synthesis (Stuttgart) (04.10.2005)
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Journal Article
Behavioral Approach to Nondyskinetic Dopamine Antagonists: Identification of Seroquel
Warawa, Edward J, Migler, Bernard M, Ohnmacht, Cyrus J, Needles, Ann L, Gatos, George C, McLaren, Frances M, Nelson, Cynthia L, Kirkland, Karen M
Published in Journal of medicinal chemistry (01.02.2001)
Published in Journal of medicinal chemistry (01.02.2001)
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Pharmacological Characterization of ZD6021: A Novel, Orally Active Antagonist of the Tachykinin Receptors
Rumsey, W L, Aharony, D, Bialecki, R A, Abbott, B M, Barthlow, H G, Caccese, R, Ghanekar, S, Lengel, D, McCarthy, M, Wenrich, B, Undem, B, Ohnmacht, C, Shenvi, A, Albert, J S, Brown, F, Bernstein, P R, Russell, K
Published in The Journal of pharmacology and experimental therapeutics (01.07.2001)
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Published in The Journal of pharmacology and experimental therapeutics (01.07.2001)
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Discovery of novel, orally active dual NK1/NK2 antagonists
BERNSTEIN, Peter R, AHARONY, David, KOSMIDER, Benedict J, KIRKLAND, Karin, OHNMACHT, Cyrus J, POTTS, William, RUMSEY, William L, LIHONG SHEN, SHENVI, Ashok, SHERWOOD, Scott, STOLLMAN, David, RUSSELL, Keith, ALBERT, Jeffrey S, ANDISIK, Donald, BARTHLOW, Herbert G, BIALECKI, Russell, DAVENPORT, Timothy, DEDINAS, Robert F, DEMBOFSKY, Bruce T, KOETHER, Gerard
Published in Bioorganic & medicinal chemistry letters (22.10.2001)
Published in Bioorganic & medicinal chemistry letters (22.10.2001)
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Journal Article
Development and SAR of functionally selective allosteric modulators of GABA A receptors
Alhambra, Cristobal, Becker, Chris, Blake, Timothy, Chang, Amy (Hui-Fang), Damewood, James R., Daniels, Thalia, Dembofsky, Bruce T., Gurley, David A., Hall, James E., Herzog, Keith J., Horchler, Carey L., Ohnmacht, Cyrus J., Schmiesing, Richard Jon, Dudley, Adam, Ribadeneira, Maria D., Knappenberger, Katherine S., Maciag, Carla, Stein, Mark M., Chopra, Maninder, Liu, Xiaodong F., Christian, Edward P., Arriza, Jeffrey L., Chapdelaine, Marc J.
Published in Bioorganic & medicinal chemistry (01.05.2011)
Published in Bioorganic & medicinal chemistry (01.05.2011)
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Journal Article
N-Aryl-3,3,3-trifluoro-2-hydroxy-2-methylpropanamides: KATP Potassium Channel Openers. Modifications on the Western Region
Ohnmacht, Cyrus J, Russell, Keith, Empfield, James R, Frank, Cathy A, Gibson, Keith H, Mayhugh, Daniel R, McLaren, Frances M, Shapiro, Howard S, Brown, Frederick J, Trainor, Diane A, Ceccarelli, Christopher, Lin, Margaret M, Masek, Brian B, Forst, Janet M, Harris, Robert J, Hulsizer, James M, Lewis, Joseph J, Silverman, Stuart M, Smith, Reed W, Warwick, Paul J, Kau, Sen T, Chun, Alexa L, Grant, Thomas L, Howe, Burton B, Li, Jack H, Trivedi, Shephali, Halterman, Tracy J, Yochim, Christopher, Dyroff, Martin C, Neilson, Kathleen L
Published in Journal of medicinal chemistry (14.03.1997)
Published in Journal of medicinal chemistry (14.03.1997)
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Journal Article
N-Aryl-3,3,3-trifluoro-2-hydroxy-2-methylpropanamides: KATP Potassium Channel Openers. Modifications on the Western Region
Ohnmacht, Cyrus J, Russell, Keith, Empfield, James R, Frank, Cathy A, Gibson, Keith H, Mayhugh, Daniel R, McLaren, Frances M, Shapiro, Howard S, Brown, Frederick J, Trainor, Diane A, Ceccarelli, Christopher, Lin, Margaret M, Masek, Brian B, Forst, Janet M, Harris, Robert J, Hulsizer, James M, Lewis, Joseph J, Silverman, Stuart M, Smith, Reed W, Warwick, Paul J, Kau, Sen T, Chun, Alexa L, Grant, Thomas L, Howe, Burton B, Li, Jack H, Trivedi, Shephali, Halterman, Tracy J, Yochim, Christopher, Dyroff, Martin C, Kirkland, M, Neilson, Kathleen L
Published in Journal of medicinal chemistry (08.11.1996)
Published in Journal of medicinal chemistry (08.11.1996)
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Journal Article
Development and SAR of functionally selective allosteric modulators of GABA sub(A receptors)
Alhambra, Cristobal, Becker, Chris, Blake, Timothy, Chang, Amy, Damewood, James R, Daniels, Thalia, Dembofsky, Bruce T, Gurley, David A, Hall, James E, Herzog, Keith J, Horchler, Carey L, Ohnmacht, Cyrus J, Schmiesing, Richard Jon, Dudley, Adam, Ribadeneira, Maria D, Knappenberger, Katherine S, Maciag, Carla, Stein, Mark M, Chopra, Maninder, Liu, Xiaodong F, Christian, Edward P, Arriza, Jeffrey L, Chapdelaine, Marc J
Published in Bioorganic & medicinal chemistry (01.05.2011)
Published in Bioorganic & medicinal chemistry (01.05.2011)
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Journal Article
Design and optimization of cyclized NK1 antagonists with controlled atropisomeric properties
Albert, JS, Ohnmacht, C, Bernstein, PR, Rumsey, WL, Aharony, D, Masek, BB, Dembofsky, BT, Koether, GM, Potts, W, Evenden, JL
Published in Tetrahedron (10.05.2004)
Published in Tetrahedron (10.05.2004)
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Journal Article
Design and optimization of cyclized NK 1 antagonists with controlled atropisomeric properties
Albert, Jeffrey S, Ohnmacht, Cyrus, Bernstein, Peter R, Rumsey, William L, Aharony, David, Masek, Brian B, Dembofsky, Bruce T, Koether, Gerard M, Potts, William, Evenden, John L
Published in Tetrahedron (2004)
Published in Tetrahedron (2004)
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Journal Article
Naphtho[2,1- b][1,5] and [1,2- f][1,4]oxazocines as selective NK 1 antagonists
Ohnmacht, Cyrus J., Albert, Jeffrey S., Bernstein, Peter R., Rumsey, William L., Masek, Brian B., Dembofsky, Bruce T., Koether, Gerard M., Andisik, Donald W., Aharony, David
Published in Bioorganic & medicinal chemistry (2004)
Published in Bioorganic & medicinal chemistry (2004)
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Journal Article
Structural analysis and optimization of NK(1) receptor antagonists through modulation of atropisomer interconversion properties
Albert, Jeffrey S, Ohnmacht, Cyrus, Bernstein, Peter R, Rumsey, William L, Aharony, David, Alelyunas, Yun, Russell, Daniel J, Potts, William, Sherwood, Scott A, Shen, Lihong, Dedinas, Robert F, Palmer, William E, Russell, Keith
Published in Journal of medicinal chemistry (29.01.2004)
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Published in Journal of medicinal chemistry (29.01.2004)
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