Soluble PD-L1 changes in advanced non-small cell lung cancer patients treated with PD-1 inhibitors: an individual patient data meta-analysis
Shimizu, Takashi, Inoue, Eisuke, Ohkuma, Ryotaro, Kobayashi, Shinichi, Tsunoda, Takuya, Wada, Satoshi
Published in Frontiers in immunology (23.11.2023)
Published in Frontiers in immunology (23.11.2023)
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Corrigendum: Soluble PD-L1 changes in advanced non-small cell lung cancer patients treated with PD-1 inhibitors: an individual patient data meta-analysis
Shimizu, Takashi, Inoue, Eisuke, Ohkuma, Ryotaro, Kobayashi, Shinichi, Tsunoda, Takuya, Wada, Satoshi
Published in Frontiers in immunology (05.12.2023)
Published in Frontiers in immunology (05.12.2023)
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A high number of PD-L1+ CD14+ monocytes in peripheral blood is correlated with shorter survival in patients receiving immune checkpoint inhibitors
Ando, Kiyohiro, Hamada, Kazuyuki, Shida, Midori, Ohkuma, Ryotaro, Kubota, Yutaro, Horiike, Atsushi, Matsui, Hiroto, Ishiguro, Tomoyuki, Hirasawa, Yuya, Ariizumi, Hirotsugu, Watanabe, Makoto, Onoue, Rie, Tsurutani, Junji, Yoshimura, Kiyoshi, Tsunoda, Takuya, Kobayashi, Shinichi, Wada, Satoshi
Published in Cancer Immunology, Immunotherapy (01.02.2021)
Published in Cancer Immunology, Immunotherapy (01.02.2021)
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Minimal contribution of the hepatic uptake transporter OATP1B1 to the inter-individual variability in SN-38 pharmacokinetics in cancer patients without severe renal failure
Tsuboya, Ayako, Kubota, Yutaro, Ishida, Hiroo, Ohkuma, Ryotaro, Ishiguro, Tomoyuki, Hirasawa, Yuya, Ariizumi, Hirotsugu, Tsunoda, Takuya, Sasaki, Yasutsuna, Matsumoto, Natsumi, Kondo, Yusuke, Tomoda, Yukana, Kusuhara, Hiroyuki, Fujita, Ken-ichi
Published in Cancer chemotherapy and pharmacology (01.09.2021)
Published in Cancer chemotherapy and pharmacology (01.09.2021)
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Lack of correlation between the costs of anticancer drugs and clinical benefits in Japan
Satoh, Etsuko, Sasaki, Yasutsuna, Ohkuma, Ryotaro, Takahashi, Takehiro, Kubota, Yutaro, Ishida, Hiroo, Hamada, Kazuyuki, Kiuchi, Yuji, Tsunoda, Takuya
Published in Cancer science (01.12.2018)
Published in Cancer science (01.12.2018)
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Antibiotic Usage Reduced Overall Survival by over 70% in Non-small Cell Lung Cancer Patients on Anti-PD-1 Immunotherapy
HAMADA, KAZUYUKI, YOSHIMURA, KIYOSHI, HIRASAWA, YUYA, HOSONUMA, MASAHIRO, MURAYAMA, MASAKAZU, NARIKAWA, YOICHIRO, ARIIZUMI, HIROTSUGU, OHKUMA, RYOTARO, SHIDA, MIDORI, KUBOTA, YUTARO, MATSUKUMA, SATOSHI, ISHIGURO, TOMOYUKI, SAMBE, TAKEHIKO, HORIIKE, ATSUSHI, KURAMASU, ATSUO, WADA, SATOSHI, TSURUTANI, JUNJI, INOUE, EISUKE, UCHIDA, NAOKI, KIUCHI, YUJI, KOBAYASHI, SHINICHI, HOFFMAN, ROBERT M., TSUNODA, TAKUYA
Published in Anticancer research (01.10.2021)
Published in Anticancer research (01.10.2021)
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The Prognostic Impact of Eosinophils and the Eosinophil-to-Lymphocyte Ratio on Survival Outcomes in Stage II Resectable Pancreatic Cancer
Ohkuma, Ryotaro, Kubota, Yutaro, Horiike, Atsushi, Ishiguro, Tomoyuki, Hirasawa, Yuya, Ariizumi, Hirotsugu, Watanabe, Makoto, Onoue, Rie, Ando, Kiyohiro, Tsurutani, Junji, Yoshimura, Kiyoshi, Aoki, Takeshi, Murakami, Masahiko, Kobayashi, Shinichi, Tsunoda, Takuya, Wada, Satoshi
Published in Pancreas (01.02.2021)
Published in Pancreas (01.02.2021)
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Turicibacter and Acidaminococcus predict immune-related adverse events and efficacy of immune checkpoint inhibitor
Hamada, Kazuyuki, Isobe, Junya, Hattori, Kouya, Hosonuma, Masahiro, Baba, Yuta, Murayama, Masakazu, Narikawa, Yoichiro, Toyoda, Hitoshi, Funayama, Eiji, Tajima, Kohei, Shida, Midori, Hirasawa, Yuya, Tsurui, Toshiaki, Ariizumi, Hirotsugu, Ishiguro, Tomoyuki, Suzuki, Risako, Ohkuma, Ryotaro, Kubota, Yutaro, Sambe, Takehiko, Tsuji, Mayumi, Wada, Satoshi, Kiuchi, Yuji, Kobayashi, Shinichi, Kuramasu, Atsuo, Horiike, Atsushi, Kim, Yun-Gi, Tsunoda, Takuya, Yoshimura, Kiyoshi
Published in Frontiers in immunology (03.05.2023)
Published in Frontiers in immunology (03.05.2023)
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Isobutyric acid enhances the anti-tumour effect of anti-PD-1 antibody
Murayama, Masakazu, Hosonuma, Masahiro, Kuramasu, Atsuo, Kobayashi, Sei, Sasaki, Akiko, Baba, Yuta, Narikawa, Yoichiro, Toyoda, Hitoshi, Isobe, Junya, Funayama, Eiji, Tajima, Kohei, Sasaki, Aya, Maruyama, Yuki, Yamazaki, Yoshitaka, Shida, Midori, Hamada, Kazuyuki, Hirasawa, Yuya, Tsurui, Toshiaki, Ariizumi, Hirotsugu, Ishiguro, Tomoyuki, Suzuki, Risako, Ohkuma, Ryotaro, Kubota, Yutaro, Horiike, Atsushi, Sambe, Takehiko, Tsuji, Mayumi, Wada, Satoshi, Kobayashi, Shinichi, Shimane, Toshikazu, Tsunoda, Takuya, Kobayashi, Hitome, Kiuchi, Yuji, Yoshimura, Kiyoshi
Published in Scientific reports (17.05.2024)
Published in Scientific reports (17.05.2024)
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A case report on severe nivolumab-induced adverse events similar to primary sclerosing cholangitis refractory to immunosuppressive therapy
Hirasawa, Yuya, Yoshimura, Kiyoshi, Matsui, Hiroto, Kubota, Yutaro, Ishida, Hiroo, Arai, Jun, Sakaki, Masashi, Oguro, Nao, Shida, Midori, Taniguchi, Makoto, Hamada, Kazuyuki, Ariizumi, Hirotsugu, Ishiguro, Tomoyuki, Ohkuma, Ryotaro, Sambe, Takehiko, Horiike, Atsushi, Imamura, Chiyo K, Shiozawa, Eisuke, Wada, Satoshi, Tsurutani, Junji, Iwamoto, Sanju, Uchida, Naoki, Kiuchi, Yuji, Tate, Genshu, Kobayashi, Shinichi, Tsunoda, Takuya
Published in Medicine (Baltimore) (11.06.2021)
Published in Medicine (Baltimore) (11.06.2021)
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High expression of olfactomedin-4 is correlated with chemoresistance and poor prognosis in pancreatic cancer
Ohkuma, Ryotaro, Yada, Erica, Ishikawa, Shumpei, Komura, Daisuke, Ishizaki, Hidenobu, Tamada, Koji, Kubota, Yutaro, Hamada, Kazuyuki, Ishida, Hiroo, Hirasawa, Yuya, Ariizumi, Hirotsugu, Satoh, Etsuko, Shida, Midori, Watanabe, Makoto, Onoue, Rie, Ando, Kiyohiro, Tsurutani, Junji, Yoshimura, Kiyoshi, Yokobori, Takehiko, Sasada, Tetsuro, Aoki, Takeshi, Murakami, Masahiko, Norose, Tomoko, Ohike, Nobuyuki, Takimoto, Masafumi, Izumizaki, Masahiko, Kobayashi, Shinichi, Tsunoda, Takuya, Wada, Satoshi
Published in PloS one (01.01.2020)
Published in PloS one (01.01.2020)
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Chemotherapy combined with immune checkpoint inhibitors may overcome the detrimental effect of high neutrophil-to-lymphocyte ratio prior to treatment in esophageal cancer patients
Hirasawa, Yuya, Kubota, Yutaro, Mura, Emiko, Suzuki, Risako, Tsurui, Toshiaki, Iriguchi, Nana, Ishiguro, Tomoyuki, Ohkuma, Ryotaro, Shimokawa, Masahiro, Ariizumi, Hirotsugu, Horiike, Atsushi, Wada, Satoshi, Yamashita, Takeshi, Ariyoshi, Tomotake, Goto, Satoru, Otsuka, Koji, Murakami, Masahiko, Kiuchi, Yuji, Yoshimura, Kiyoshi, Tsunoda, Takuya
Published in Frontiers in oncology (11.10.2024)
Published in Frontiers in oncology (11.10.2024)
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Case Report: Combined pembrolizumab, 5-fluorouracil, and cisplatin therapy were remarkably effective in p16-positive squamous cell carcinoma of unknown primary
Suzuki, Risako, Hamada, Kazuyuki, Ohkuma, Ryotaro, Homma, Mayumi, Tsurui, Toshiaki, Iriguchi, Nana, Ishiguro, Tomoyuki, Hirasawa, Yuya, Ariizumi, Hirotsugu, Kubota, Yutaro, Horiike, Atsushi, Yoshimura, Kiyoshi, Wada, Satoshi, Yamochi, Toshiko, Tsunoda, Takuya
Published in Frontiers in oncology (10.07.2023)
Published in Frontiers in oncology (10.07.2023)
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Increased Plasma Soluble PD-1 Concentration Correlates with Disease Progression in Patients with Cancer Treated with Anti-PD-1 Antibodies
Ohkuma, Ryotaro, Ieguchi, Katsuaki, Watanabe, Makoto, Takayanagi, Daisuke, Goshima, Tsubasa, Onoue, Rie, Hamada, Kazuyuki, Kubota, Yutaro, Horiike, Atsushi, Ishiguro, Tomoyuki, Hirasawa, Yuya, Ariizumi, Hirotsugu, Tsurutani, Junji, Yoshimura, Kiyoshi, Tsuji, Mayumi, Kiuchi, Yuji, Kobayashi, Shinichi, Tsunoda, Takuya, Wada, Satoshi
Published in Biomedicines (16.12.2021)
Published in Biomedicines (16.12.2021)
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Variants of carboxylesterase 1 have no impact on capecitabine pharmacokinetics and toxicity in capecitabine plus oxaliplatin treated-colorectal cancer patients
Matsumoto, Natsumi, Kubota, Yutaro, Ishida, Hiroo, Sekido, Masae, Ohkuma, Ryotaro, Ishiguro, Tomoyuki, Hirasawa, Yuya, Ariizumi, Hirotsugu, Tsunoda, Takuya, Ikusue, Toshikazu, Kobayashi, Kouji, Hisamatsu, Atsushi, Toshima, Hirokazu, Shimada, Ken, Fujita, Ken-ichi
Published in Cancer chemotherapy and pharmacology (01.06.2020)
Published in Cancer chemotherapy and pharmacology (01.06.2020)
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Novel quantitative immunohistochemical analysis for evaluating PD-L1 expression with phosphor-integrated dots for predicting the efficacy of patients with cancer treated with immune checkpoint inhibitors
Ohkuma, Ryotaro, Miura, Sakiko, Muto, Satoshi, Toyomasu, Yoshitaka, Fujimoto, Yuki, Ieguchi, Katsuaki, Onishi, Nobuyuki, Shimizu, Takashi, Watanabe, Makoto, Takayanagi, Daisuke, Goshima, Tsubasa, Horiike, Atsushi, Hamada, Kazuyuki, Ariizumi, Hirotsugu, Shimokawa, Masahiro, Hirasawa, Yuya, Ishiguro, Tomoyuki, Suzuki, Risako, Iriguchi, Nana, Tsurui, Toshiaki, Mura, Emiko, Takenoshita, Sachiko, Numajiri, Kazuki, Okabe, Naoyuki, Yoshimura, Kiyoshi, Tsuji, Mayumi, Kiuchi, Yuji, Yajima, Toshiki, Ishida, Hideyuki, Suzuki, Hiroyuki, Yamochi, Toshiko, Kobayashi, Shinichi, Tsunoda, Takuya, Wada, Satoshi
Published in Frontiers in immunology (18.09.2023)
Published in Frontiers in immunology (18.09.2023)
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Plasma Levels of Soluble PD-L1 Correlate With Tumor Regression in Patients With Lung and Gastric Cancer Treated With Immune Checkpoint Inhibitors
Ando, Kiyohiro, Hamada, Kazuyuki, Watanabe, Makoto, Ohkuma, Ryotaro, Shida, Midori, Onoue, Rie, Kubota, Yutaro, Matsui, Hiroto, Ishiguro, Tomoyuki, Hirasawa, Yuya, Ariizumi, Hirotsugu, Tsurutani, Junji, Yoshimura, Kiyoshi, Tsunoda, Takuya, Kobayashi, Shinichi, Wada, Satoshi
Published in Anticancer research (01.09.2019)
Published in Anticancer research (01.09.2019)
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O16-5 Nivolumab for cancer of unknown primary (CUP): Initial results from an expanded access program (NivoCUP2, WJOG14620M)
Tanizaki, Junko, Yonemori, Kan, Takiguchi, Yuichi, Akiyoshi, Kohei, Komine, Keigo, Onozawa, Yusuke, Sato, Mariko, Hirata, Kenro, Onoe, Takuma, Ohkuma, Ryotaro, Horita, Yosuke, Minami, Hironobu, Honda, Kazunori, Suyama, Koichi, Ito, Akihiko, Chiba, Yasutaka, Nishio, Kazuto, Hayashi, Hidetoshi
Published in Annals of oncology (01.11.2023)
Published in Annals of oncology (01.11.2023)
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A case of bronchial asthma as an immune-related adverse event of pembrolizumab treatment for bladder cancer: A case report
Hamada, Kazuyuki, Yoshimura, Kiyoshi, Oshinomi, Kazuhiko, Hirasawa, Yuya, Ariizumi, Hirotsugu, Ohkuma, Ryotaro, Shida, Midori, Kubota, Yutaro, Matsui, Hiroto, Ishiguro, Tomoyuki, Sambe, Takehiko, Ishida, Hiroo, Horiike, Atsushi, Wada, Satoshi, Iwamoto, Sanju, Uchida, Naoki, Ogawa, Yoshio, Kobayashi, Shinichi, Tsunoda, Takuya
Published in Medicine (Baltimore) (14.01.2022)
Published in Medicine (Baltimore) (14.01.2022)
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Immune Environment and Immunotherapy in Endometrial Carcinoma and Cervical Tumors
Lainé, Alexandra, Gonzalez-Lopez, Andrea M, Hasan, Uzma, Ohkuma, Ryotaro, Ray-Coquard, Isabelle
Published in Cancers (29.03.2023)
Published in Cancers (29.03.2023)
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