Mesothelin-targeting T cell receptor fusion construct cell therapy in refractory solid tumors: phase 1/2 trial interim results
Hassan, Raffit, Butler, Marcus, O'Cearbhaill, Roisin E, Oh, David Y, Johnson, Melissa, Zikaras, Kevin, Smalley, Munisha, Ross, Michael, Tanyi, Janos L, Ghafoor, Azam, Shah, Nirali N, Saboury, Babak, Cao, Liang, Quintás-Cardama, Alfonso, Hong, David
Published in Nature medicine (01.08.2023)
Published in Nature medicine (01.08.2023)
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Neoadjuvant sipuleucel-T induces both Th1 activation and immune regulation in localized prostate cancer
Hagihara, Katsunobu, Chan, Stephen, Zhang, Li, Oh, David Y., Wei, Xiao X., Simko, Jeffry, Fong, Lawrence
Published in Oncoimmunology (01.01.2019)
Published in Oncoimmunology (01.01.2019)
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Single-cell and spatial multi-omics highlight effects of anti-integrin therapy across cellular compartments in ulcerative colitis
Mennillo, Elvira, Kim, Yang Joon, Lee, Gyehyun, Rusu, Iulia, Patel, Ravi K, Dorman, Leah C, Flynn, Emily, Li, Stephanie, Bain, Jared L, Andersen, Christopher, Rao, Arjun, Tamaki, Stanley, Tsui, Jessica, Shen, Alan, Lotstein, Madison L, Rahim, Maha, Naser, Mohammad, Bernard-Vazquez, Faviola, Eckalbar, Walter, Cho, Soo-Jin, Beck, Kendall, El-Nachef, Najwa, Lewin, Sara, Selvig, Daniel R, Terdiman, Jonathan P, Mahadevan, Uma, Oh, David Y, Fragiadakis, Gabriela K, Pisco, Angela, Combes, Alexis J, Kattah, Michael G
Published in Nature communications (19.02.2024)
Published in Nature communications (19.02.2024)
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In Vivo Measurement of Granzyme Proteolysis from Activated Immune Cells with PET
Zhao, Ning, Bardine, Conner, Lourenço, André Luiz, Wang, Yung-hua, Huang, Yangjie, Cleary, Simon J, Wilson, David M, Oh, David Y, Fong, Lawrence, Looney, Mark R, Evans, Michael J, Craik, Charles S
Published in ACS central science (27.10.2021)
Published in ACS central science (27.10.2021)
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TERT promoter mutations and other prognostic factors in patients with advanced urothelial carcinoma treated with an immune checkpoint inhibitor
de Kouchkovsky, Ivan, Zhang, Li, Philip, Errol J, Wright, Francis, Kim, Daniel M, Natesan, Divya, Kwon, Daniel, Ho, Hansen, Ho, Son, Chan, Emily, Porten, Sima P, Wong, Anthony C, Desai, Arpita, Huang, Franklin W, Chou, Jonathan, Oh, David Y, Pruthi, Raj S, Fong, Lawrence, Small, Eric J, Friedlander, Terence W, Koshkin, Vadim S
Published in Journal for immunotherapy of cancer (01.05.2021)
Published in Journal for immunotherapy of cancer (01.05.2021)
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Immune Toxicities Elicted by CTLA-4 Blockade in Cancer Patients Are Associated with Early Diversification of the T-cell Repertoire
Oh, David Y, Cham, Jason, Zhang, Li, Fong, Grant, Kwek, Serena S, Klinger, Mark, Faham, Malek, Fong, Lawrence
Published in Cancer research (Chicago, Ill.) (15.03.2017)
Published in Cancer research (Chicago, Ill.) (15.03.2017)
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Intratumoral CD4+ T Cells Mediate Anti-tumor Cytotoxicity in Human Bladder Cancer
Oh, David Y., Kwek, Serena S., Raju, Siddharth S., Li, Tony, McCarthy, Elizabeth, Chow, Eric, Aran, Dvir, Ilano, Arielle, Pai, Chien-Chun Steven, Rancan, Chiara, Allaire, Kathryn, Burra, Arun, Sun, Yang, Spitzer, Matthew H., Mangul, Serghei, Porten, Sima, Meng, Maxwell V., Friedlander, Terence W., Ye, Chun Jimmie, Fong, Lawrence
Published in Cell (25.06.2020)
Published in Cell (25.06.2020)
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Toward a better understanding of T cells in cancer
Oh, David Y., Fong, Lawrence, Newell, Evan W., Turk, Mary Jo, Chi, Hongbo, Chang, Howard Y., Satpathy, Ansuman T., Fairfax, Benjamin, Silva-Santos, Bruno, Lantz, Olivier
Published in Cancer cell (13.12.2021)
Published in Cancer cell (13.12.2021)
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Mechanisms and clinical manifestations of cardiovascular toxicities associated with immune checkpoint inhibitors
Baik, Alan H, Tsai, Katy K, Oh, David Y, Aras, Mandar A
Published in Clinical science (1979) (12.03.2021)
Published in Clinical science (1979) (12.03.2021)
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Clonal Deletion of Tumor-Specific T Cells by Interferon-γ Confers Therapeutic Resistance to Combination Immune Checkpoint Blockade
Pai, Chien-Chun Steven, Huang, John T., Lu, Xiaoqing, Simons, Donald M., Park, Chanhyuk, Chang, Anthony, Tamaki, Whitney, Liu, Eric, Roybal, Kole T., Seagal, Jane, Chen, Mingyi, Hagihara, Katsunobu, Wei, Xiao X., DuPage, Michel, Kwek, Serena S., Oh, David Y., Daud, Adil, Tsai, Katy K., Wu, Clint, Zhang, Li, Fasso, Marcella, Sachidanandam, Ravi, Jayaprakash, Anitha, Lin, Ingrid, Casbon, Amy-Jo, Kinsbury, Gillian A., Fong, Lawrence
Published in Immunity (Cambridge, Mass.) (19.02.2019)
Published in Immunity (Cambridge, Mass.) (19.02.2019)
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Androgen conspires with the CD8 + T cell exhaustion program and contributes to sex bias in cancer
Kwon, Hyunwoo, Schafer, Johanna M, Song, No-Joon, Kaneko, Satoshi, Li, Anqi, Xiao, Tong, Ma, Anjun, Allen, Carter, Das, Komal, Zhou, Lei, Riesenberg, Brian, Chang, Yuzhou, Weltge, Payton, Velegraki, Maria, Oh, David Y, Fong, Lawrence, Ma, Qin, Sundi, Debasish, Chung, Dongjun, Li, Xue, Li, Zihai
Published in Science immunology (01.07.2022)
Published in Science immunology (01.07.2022)
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Early changes in the circulating T cells are associated with clinical outcomes after PD-L1 blockade by durvalumab in advanced NSCLC patients
Naidus, Elliot, Bouquet, Jerome, Oh, David Y., Looney, Timothy J., Yang, Hai, Fong, Lawrence, Standifer, Nathan E., Zhang, Li
Published in Cancer Immunology, Immunotherapy (01.07.2021)
Published in Cancer Immunology, Immunotherapy (01.07.2021)
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Journal Article
Molecular and Radiological Features of Microsatellite Stable Colorectal Cancer Cases With Dramatic Responses to Immunotherapy
KEENAN, BRIDGET P., VAN LOON, KATHERINE, KHILNANI, ANURADHA D., FIDELMAN, NICHOLAS, BEHR, SPENCER C., ATREYA, CHLOE E., OH, DAVID Y.
Published in Anticancer research (01.06.2021)
Published in Anticancer research (01.06.2021)
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