Comparison of Claudin 18.2 expression in primary tumors and lymph node metastases in Japanese patients with gastric adenocarcinoma
Rohde, Christoph, Yamaguchi, Rin, Mukhina, Svetlana, Sahin, Ugur, Itoh, Kyogo, Türeci, Özlem
Published in Japanese journal of clinical oncology (01.09.2019)
Published in Japanese journal of clinical oncology (01.09.2019)
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Patient-reported outcomes from the phase II FAST trial of zolbetuximab plus EOX compared to EOX alone as first-line treatment of patients with metastatic CLDN18.2+ gastroesophageal adenocarcinoma
Lordick, Florian, Al-Batran, Salah-Eddin, Ganguli, Arijit, Morlock, Robert, Sahin, Ugur, Türeci, Özlem
Published in Gastric cancer : official journal of the International Gastric Cancer Association and the Japanese Gastric Cancer Association (01.05.2021)
Published in Gastric cancer : official journal of the International Gastric Cancer Association and the Japanese Gastric Cancer Association (01.05.2021)
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1181 GEN1042-mIgG2a, an Fc-inert mouse-human chimeric variant of GEN1042 (DuoBody®-CD40x4–1BB), exhibits in vivo antitumor activity and peripheral immune modulation
Pilones, Karsten, Sette, Angelica, Nuermberger, Kristina, Luijten, Monique, Köhne, Maren, Wolthoorn, Jasja, Muik, Alexander, Fellermeier-Kopf, Sina, Ahmadi, Tahamtan, Tuereci, Oezlem, Sahin, Ugur, Jure-Kunkel, Maria, Adams, Homer
Published in Journal for immunotherapy of cancer (01.11.2023)
Published in Journal for immunotherapy of cancer (01.11.2023)
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813 Combination of HexaBody-CD27 with PD-(L)1 blockade potentiates single-agent activity leading to enhanced human T-cell effector functions in vitro
Imle, Andrea, Altintas, Isil, Nuermberger, Kristina, Blum, Jordan, Krause, Anna-Lena, Toker, Aras, Daszkiewicz, Lidia, Muik, Alexander, Gieseke, Friederike, Ahmadi, Tahamtan, Fellermeier-Kopf, Sina, Kemper, Kristel, Tuereci, Oezlem, Breij, Esther, Sahin, Ugur
Published in Journal for immunotherapy of cancer (01.11.2023)
Published in Journal for immunotherapy of cancer (01.11.2023)
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597 Preliminary results from LuCa-MERIT-1, a first-in-human Phase I trial evaluating the fixed antigen RNA vaccine BNT116 in patients with advanced non-small cell lung cancer
Deme, Dániel, Öven, Bala, Göker, Erdem, Lang, Istvan, Brück, Patrick, Wenger, Michael, Munshi, Neru, Schell, Thomas, Ünsal-Kaçmaz, Kezi, Markman, Janet, Rietschel, Petra, Yang, Huyuan, Tuereci, Oezlem, Sahin, Ugur, Atmaca, Akin, Forde, Patrick
Published in Journal for immunotherapy of cancer (01.11.2023)
Published in Journal for immunotherapy of cancer (01.11.2023)
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Generation of tissue-specific and promiscuous HLA ligand databases using DNA microarrays and virtual HLA class II matrices
Hammer, Juergen, Sturniolo, Tiziana, Bono, Elisa, Ding, Jiayi, Raddrizzani, Laura, Tuereci, Oezlem, Sahin, Ugur, Braxenthaler, Michael, Gallazzi, Fabio, Protti, Maria Pia, Sinigaglia, Francesco
Published in Nature biotechnology (01.06.1999)
Published in Nature biotechnology (01.06.1999)
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958 BNT211: a phase I/II trial to evaluate safety and efficacy of CLDN6 CAR-T cells and vaccine-mediated in vivo expansion in patients with CLDN6-positive advanced solid tumors
Mackensen, Andreas, Koenecke, Christian, Haanen, John, Alsdorf, Winfried, Desuki, Alexander, Wagner-Drouet, Eva, Heudobler, Daniel, Borchmann, Peter, Wiegert, Erol, Schulz, Catrine, Rengstl, Benjamin, Preussner, Liane, Tuereci, Oezlem, Sahin, Ugur
Published in Journal for immunotherapy of cancer (01.11.2021)
Published in Journal for immunotherapy of cancer (01.11.2021)
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525 Preliminary safety, PK/PD and efficacy results from a first-in-human phase I/IIa clinical trial of BNT411, a systemic Toll-like receptor 7 agonist in patients with solid tumors
Symeonides, Stefan, Mahalingam, Devalingam, Chae, Young Kwang, Calvo, Emiliano, Miguel, Maria, Arkenau, Hendrik-Tobias, Garralda, Elena, Galvao, Vladimir, Mita, Alain, Hassan, Hariz, Baumhauer, Annette, Völker, Timo, Kühnle, Marie-Cristine, Rösemann, Roman, Strobl, Stefan, Tuereci, Oezlem, Sahin, Ugur
Published in Journal for immunotherapy of cancer (01.11.2021)
Published in Journal for immunotherapy of cancer (01.11.2021)
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Journal Article
mRNA-based therapeutics — developing a new class of drugs
Sahin, Ugur, Karikó, Katalin, Türeci, Özlem
Published in Nature reviews. Drug discovery (01.10.2014)
Published in Nature reviews. Drug discovery (01.10.2014)
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Identification of neoantigens for individualized therapeutic cancer vaccines
Lang, Franziska, Schrörs, Barbara, Löwer, Martin, Türeci, Özlem, Sahin, Ugur
Published in Nature reviews. Drug discovery (01.04.2022)
Published in Nature reviews. Drug discovery (01.04.2022)
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Targeting the Heterogeneity of Cancer with Individualized Neoepitope Vaccines
Türeci, Özlem, Vormehr, Mathias, Diken, Mustafa, Kreiter, Sebastian, Huber, Christoph, Sahin, Ugur
Published in Clinical cancer research (15.04.2016)
Published in Clinical cancer research (15.04.2016)
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Neutralization of SARS-CoV-2 lineage B.1.1.7 pseudovirus by BNT162b2 vaccine-elicited human sera
Muik, Alexander, Wallisch, Ann-Kathrin, Sänger, Bianca, Swanson, Kena A, Mühl, Julia, Chen, Wei, Cai, Hui, Maurus, Daniel, Sarkar, Ritu, Türeci, Özlem, Dormitzer, Philip R, Şahin, Uğur
Published in Science (12.03.2021)
Published in Science (12.03.2021)
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An RNA vaccine drives immunity in checkpoint-inhibitor-treated melanoma
Sahin, Ugur, Oehm, Petra, Derhovanessian, Evelyna, Jabulowsky, Robert A., Vormehr, Mathias, Gold, Maike, Maurus, Daniel, Schwarck-Kokarakis, Doreen, Kuhn, Andreas N., Omokoko, Tana, Kranz, Lena M., Diken, Mustafa, Kreiter, Sebastian, Haas, Heinrich, Attig, Sebastian, Rae, Richard, Cuk, Katarina, Kemmer-Brück, Alexandra, Breitkreuz, Andrea, Tolliver, Claudia, Caspar, Janina, Quinkhardt, Juliane, Hebich, Lisa, Stein, Malte, Hohberger, Alexander, Vogler, Isabel, Liebig, Inga, Renken, Stephanie, Sikorski, Julian, Leierer, Melanie, Müller, Verena, Mitzel-Rink, Heidrun, Miederer, Matthias, Huber, Christoph, Grabbe, Stephan, Utikal, Jochen, Pinter, Andreas, Kaufmann, Roland, Hassel, Jessica C., Loquai, Carmen, Türeci, Özlem
Published in Nature (London) (03.09.2020)
Published in Nature (London) (03.09.2020)
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Mutant MHC class II epitopes drive therapeutic immune responses to cancer
Kreiter, Sebastian, Vormehr, Mathias, van de Roemer, Niels, Diken, Mustafa, Löwer, Martin, Diekmann, Jan, Boegel, Sebastian, Schrörs, Barbara, Vascotto, Fulvia, Castle, John C., Tadmor, Arbel D., Schoenberger, Stephen P., Huber, Christoph, Türeci, Özlem, Sahin, Ugur
Published in Nature (London) (30.04.2015)
Published in Nature (London) (30.04.2015)
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Systemic RNA delivery to dendritic cells exploits antiviral defence for cancer immunotherapy
Kranz, Lena M., Diken, Mustafa, Haas, Heinrich, Kreiter, Sebastian, Loquai, Carmen, Reuter, Kerstin C., Meng, Martin, Fritz, Daniel, Vascotto, Fulvia, Hefesha, Hossam, Grunwitz, Christian, Vormehr, Mathias, Hüsemann, Yves, Selmi, Abderraouf, Kuhn, Andreas N., Buck, Janina, Derhovanessian, Evelyna, Rae, Richard, Attig, Sebastian, Diekmann, Jan, Jabulowsky, Robert A., Heesch, Sandra, Hassel, Jessica, Langguth, Peter, Grabbe, Stephan, Huber, Christoph, Türeci, Özlem, Sahin, Ugur
Published in Nature (London) (16.06.2016)
Published in Nature (London) (16.06.2016)
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Journal Article
COVID-19 vaccine BNT162b1 elicits human antibody and TH1 T cell responses
Sahin, Ugur, Muik, Alexander, Derhovanessian, Evelyna, Vogler, Isabel, Kranz, Lena M., Vormehr, Mathias, Baum, Alina, Pascal, Kristen, Quandt, Jasmin, Maurus, Daniel, Brachtendorf, Sebastian, Lörks, Verena, Sikorski, Julian, Hilker, Rolf, Becker, Dirk, Eller, Ann-Kathrin, Grützner, Jan, Boesler, Carsten, Rosenbaum, Corinna, Kühnle, Marie-Cristine, Luxemburger, Ulrich, Kemmer-Brück, Alexandra, Langer, David, Bexon, Martin, Bolte, Stefanie, Karikó, Katalin, Palanche, Tania, Fischer, Boris, Schultz, Armin, Shi, Pei-Yong, Fontes-Garfias, Camila, Perez, John L., Swanson, Kena A., Loschko, Jakob, Scully, Ingrid L., Cutler, Mark, Kalina, Warren, Kyratsous, Christos A., Cooper, David, Dormitzer, Philip R., Jansen, Kathrin U., Türeci, Özlem
Published in Nature (London) (22.10.2020)
Published in Nature (London) (22.10.2020)
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Neutralization of SARS-CoV-2 Omicron by BNT162b2 mRNA vaccine-elicited human sera
Muik, Alexander, Lui, Bonny Gaby, Wallisch, Ann-Kathrin, Bacher, Maren, Mühl, Julia, Reinholz, Jonas, Ozhelvaci, Orkun, Beckmann, Nina, Güimil Garcia, Ramón de la Caridad, Poran, Asaf, Shpyro, Svetlana, Finlayson, Andrew, Cai, Hui, Yang, Qi, Swanson, Kena A, Türeci, Özlem, Şahin, Uğur
Published in Science (American Association for the Advancement of Science) (11.02.2022)
Published in Science (American Association for the Advancement of Science) (11.02.2022)
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Phase I/II study of COVID-19 RNA vaccine BNT162b1 in adults
Mulligan, Mark J., Lyke, Kirsten E., Kitchin, Nicholas, Absalon, Judith, Gurtman, Alejandra, Lockhart, Stephen, Neuzil, Kathleen, Raabe, Vanessa, Bailey, Ruth, Swanson, Kena A., Li, Ping, Koury, Kenneth, Kalina, Warren, Cooper, David, Fontes-Garfias, Camila, Shi, Pei-Yong, Türeci, Özlem, Tompkins, Kristin R., Walsh, Edward E., Frenck, Robert, Falsey, Ann R., Dormitzer, Philip R., Gruber, William C., Şahin, Uğur, Jansen, Kathrin U.
Published in Nature (London) (22.10.2020)
Published in Nature (London) (22.10.2020)
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Personalized RNA neoantigen vaccines stimulate T cells in pancreatic cancer
Rojas, Luis A., Sethna, Zachary, Soares, Kevin C., Olcese, Cristina, Pang, Nan, Patterson, Erin, Lihm, Jayon, Ceglia, Nicholas, Guasp, Pablo, Chu, Alexander, Yu, Rebecca, Chandra, Adrienne Kaya, Waters, Theresa, Ruan, Jennifer, Amisaki, Masataka, Zebboudj, Abderezak, Odgerel, Zagaa, Payne, George, Derhovanessian, Evelyna, Müller, Felicitas, Rhee, Ina, Yadav, Mahesh, Dobrin, Anton, Sadelain, Michel, Łuksza, Marta, Cohen, Noah, Tang, Laura, Basturk, Olca, Gönen, Mithat, Katz, Seth, Do, Richard Kinh, Epstein, Andrew S., Momtaz, Parisa, Park, Wungki, Sugarman, Ryan, Varghese, Anna M., Won, Elizabeth, Desai, Avni, Wei, Alice C., D’Angelica, Michael I., Kingham, T. Peter, Mellman, Ira, Merghoub, Taha, Wolchok, Jedd D., Sahin, Ugur, Türeci, Özlem, Greenbaum, Benjamin D., Jarnagin, William R., Drebin, Jeffrey, O’Reilly, Eileen M., Balachandran, Vinod P.
Published in Nature (London) (01.06.2023)
Published in Nature (London) (01.06.2023)
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