Inhibition of histone H3K27 demethylases selectively modulates inflammatory phenotypes of natural killer cells
Cribbs, Adam, Hookway, Edward S., Wells, Graham, Lindow, Morten, Obad, Susanna, Oerum, Henrik, Prinjha, Rab K., Athanasou, Nick, Sowman, Aneka, Philpott, Martin, Penn, Henry, Soderstrom, Kalle, Feldmann, Marc, Oppermann, Udo
Published in The Journal of biological chemistry (16.02.2018)
Published in The Journal of biological chemistry (16.02.2018)
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Histone H3K27me3 demethylases regulate human Th17 cell development and effector functions by impacting on metabolism
Cribbs, Adam P., Terlecki-Zaniewicz, Stefan, Philpott, Martin, Baardman, Jeroen, Ahern, David, Lindow, Morten, Obad, Susanna, Oerum, Henrik, Sampey, Brante, Mander, Palwinder K., Penn, Henry, Wordsworth, Paul, Bowness, Paul, de Winther, Menno, Prinjha, Rab K., Feldmann, Marc, Oppermann, Udo
Published in Proceedings of the National Academy of Sciences - PNAS (17.03.2020)
Published in Proceedings of the National Academy of Sciences - PNAS (17.03.2020)
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A cytoplasmic pathway for gapmer antisense oligonucleotide-mediated gene silencing in mammalian cells
Castanotto, Daniela, Lin, Min, Kowolik, Claudia, Wang, LiAnn, Ren, Xiao-Qin, Soifer, Harris S, Koch, Troels, Hansen, Bo Rode, Oerum, Henrik, Armstrong, Brian, Wang, Zhigang, Bauer, Paul, Rossi, John, Stein, C A
Published in Nucleic acids research (30.10.2015)
Published in Nucleic acids research (30.10.2015)
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Dissecting the Role of BET Bromodomain Proteins BRD2 and BRD4 in Human NK Cell Function
Cribbs, Adam P, Filippakopoulos, Panagis, Philpott, Martin, Wells, Graham, Penn, Henry, Oerum, Henrik, Valge-Archer, Viia, Feldmann, Marc, Oppermann, Udo
Published in Frontiers in immunology (26.02.2021)
Published in Frontiers in immunology (26.02.2021)
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Potent and Nontoxic Antisense Oligonucleotides Containing Locked Nucleic Acids
Wahlestedt, Claes, Salmi, Peter, Good, Liam, Kela, Johanna, Johnsson, Thomas, Hokfelt, Tomas, Broberger, Christian, Porreca, Frank, Lai, Josephine, Ren, Kunkun, Ossipov, Michael, Koshkin, Alexei, Jakobsen, Nana, Skouv, Jan, Oerum, Henrik, Jacobsen, Mogens Havsteen, Wengel, Jesper
Published in Proceedings of the National Academy of Sciences - PNAS (09.05.2000)
Published in Proceedings of the National Academy of Sciences - PNAS (09.05.2000)
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Short locked nucleic acid antisense oligonucleotides potently reduce apolipoprotein B mRNA and serum cholesterol in mice and non-human primates
Straarup, Ellen Marie, Fisker, Niels, Hedtjärn, Maj, Lindholm, Marie W, Rosenbohm, Christoph, Aarup, Vibeke, Hansen, Henrik Frydenlund, Ørum, Henrik, Hansen, Jens B. Rode, Koch, Troels
Published in Nucleic acids research (01.11.2010)
Published in Nucleic acids research (01.11.2010)
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Efficient gene silencing by delivery of locked nucleic acid antisense oligonucleotides, unassisted by transfection reagents
Stein, C.A, Hansen, J. Bo, Lai, Johnathan, Wu, SiJian, Voskresenskiy, Anatoliy, Høg, Anja, Worm, Jesper, Hedtjärn, Maj, Souleimanian, Naira, Miller, Paul, Soifer, Harris S, Castanotto, Daniella, Benimetskaya, Luba, Ørum, Henrik, Koch, Troels
Published in Nucleic acids research (01.01.2010)
Published in Nucleic acids research (01.01.2010)
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A locked nucleic acid antisense oligonucleotide (LNA) silences PCSK9 and enhances LDLR expression in vitro and in vivo
Gupta, Nidhi, Fisker, Niels, Asselin, Marie-Claude, Lindholm, Marie, Rosenbohm, Christoph, Ørum, Henrik, Elmén, Joacim, Seidah, Nabil G, Straarup, Ellen Marie
Published in PloS one (17.05.2010)
Published in PloS one (17.05.2010)
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A simple, safe and sensitive method for SARS‐CoV‐2 inactivation and RNA extraction for RT‐qPCR
Kalnina, Lelde, Mateu‐Regué, Àngels, Oerum, Stephanie, Hald, Annemette, Gerstoft, Jan, Oerum, Henrik, Nielsen, Finn Cilius, Iversen, Astrid K. N.
Published in APMIS (01.07.2021)
Published in APMIS (01.07.2021)
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Hepatotoxic Potential of Therapeutic Oligonucleotides Can Be Predicted from Their Sequence and Modification Pattern
Hagedorn, Peter H., Yakimov, Victor, Ottosen, Søren, Kammler, Susanne, Nielsen, Niels F., Høg, Anja M., Hedtjärn, Maj, Meldgaard, Michael, Møller, Marianne R., Ørum, Henrik, Koch, Troels, Lindow, Morten
Published in Nucleic acid therapeutics (01.10.2013)
Published in Nucleic acid therapeutics (01.10.2013)
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Quantum Mechanical Studies of DNA and LNA
Koch, Troels, Shim, Irene, Lindow, Morten, Ørum, Henrik, Bohr, Henrik G.
Published in Nucleic acid therapeutics (01.04.2014)
Published in Nucleic acid therapeutics (01.04.2014)
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Histone Demethylase Inhibition As a Novel Therapeutic Strategy in Myeloma
Pawlyn, Charlotte, Hookway, Edward, Cain, Peter, Pliuskys, Laurynas, Kaiser, Martin F, Bright, Michael, Aronson, Lauren I, Murison, Alexander, Lindow, Morten, Obad, Susanna, Oerum, Henrik, Opperman, Udo, Morgan, Gareth J., Davies, Faith E
Published in Blood (06.12.2014)
Published in Blood (06.12.2014)
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In vivo tumor growth inhibition and biodistribution studies of locked nucleic acid (LNA) antisense oligonucleotides
Fluiter, Kees, ten Asbroek, Anneloor L. M. A., de Wissel, Marit B., Jakobs, Marja E., Wissenbach, Margit, Olsson, Håkan, Olsen, Otto, Oerum, Henrik, Baas, Frank
Published in Nucleic acids research (01.02.2003)
Published in Nucleic acids research (01.02.2003)
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Abstract SY31-02: Locked nucleic acid (LNA)-modified antisense oligonucleotides as anticancer agents: Using high-affinity antisense molecules in the laboratory and in the clinic
Levin, Arthur A., Greenberger, Lee M., Buchbinder, Aby, Hansen, Bo R., Hedtjärn, Maj, Kauppinen, Sakari, Oerum, Henrik, Horak, Ivan D.
Published in Cancer research (Chicago, Ill.) (15.04.2011)
Published in Cancer research (Chicago, Ill.) (15.04.2011)
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On the in vitro and in vivo Properties of Four Locked Nucleic Acid Nucleotides Incorporated into an Anti-H-Ras Antisense Oligonucleotide
Fluiter, Kees, Frieden, Miriam, Vreijling, Jeroen, Rosenbohm, Christoph, De Wissel, Marit B, Christensen, Signe M, Koch, Troels, Ørum, Henrik, Baas, Frank
Published in Chembiochem : a European journal of chemical biology (01.06.2005)
Published in Chembiochem : a European journal of chemical biology (01.06.2005)
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