Discovery of Molidustat (BAY 85‐3934): A Small‐Molecule Oral HIF‐Prolyl Hydroxylase (HIF‐PH) Inhibitor for the Treatment of Renal Anemia
Beck, Hartmut, Jeske, Mario, Thede, Kai, Stoll, Friederike, Flamme, Ingo, Akbaba, Metin, Ergüden, Jens‐Kerim, Karig, Gunter, Keldenich, Jörg, Oehme, Felix, Militzer, Hans‐Christian, Hartung, Ingo V., Thuss, Uwe
Published in ChemMedChem (23.05.2018)
Published in ChemMedChem (23.05.2018)
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Journal Article
BAY 87‐2243, a highly potent and selective inhibitor of hypoxia‐induced gene activation has antitumor activities by inhibition of mitochondrial complex I
Ellinghaus, Peter, Heisler, Iring, Unterschemmann, Kerstin, Haerter, Michael, Beck, Hartmut, Greschat, Susanne, Ehrmann, Alexander, Summer, Holger, Flamme, Ingo, Oehme, Felix, Thierauch, Karlheinz, Michels, Martin, Hess‐Stumpp, Holger, Ziegelbauer, Karl
Published in Cancer medicine (Malden, MA) (01.10.2013)
Published in Cancer medicine (Malden, MA) (01.10.2013)
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Design, Synthesis, Enzyme-Inhibitory Activity, and Effect on Human Cancer Cells of a Novel Series of Jumonji Domain-Containing Protein 2 Histone Demethylase Inhibitors
Hamada, Shohei, Suzuki, Takayoshi, Mino, Koshiki, Koseki, Koichi, Oehme, Felix, Flamme, Ingo, Ozasa, Hiroki, Itoh, Yukihiro, Ogasawara, Daisuke, Komaarashi, Haruka, Kato, Aiko, Tsumoto, Hiroki, Nakagawa, Hidehiko, Hasegawa, Makoto, Sasaki, Ryuzo, Mizukami, Tamio, Miyata, Naoki
Published in Journal of medicinal chemistry (12.08.2010)
Published in Journal of medicinal chemistry (12.08.2010)
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Thermographic Stall Detection by Model-Inspired Evaluation of the Dynamic Temperature Behaviour
Oehme, Felix, Suhr, Janick, Balaresque, Nicholas, Gleichauf, Daniel, Sorg, Michael, Fischer, Andreas
Published in Applied sciences (01.09.2021)
Published in Applied sciences (01.09.2021)
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Journal Article
Copper-dependent activation of hypoxia-inducible factor (HIF)-1: implications for ceruloplasmin regulation
Martin, Falk, Linden, Tobias, Katschinski, Dörthe M., Oehme, Felix, Flamme, Ingo, Mukhopadhyay, Chinmay K., Eckhardt, Katrin, Tröger, Juliane, Barth, Sandra, Camenisch, Gieri, Wenger, Roland H.
Published in Blood (15.06.2005)
Published in Blood (15.06.2005)
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Nuclear Oxygen Sensing: Induction of Endogenous Prolyl-hydroxylase 2 Activity by Hypoxia and Nitric Oxide
Berchner-Pfannschmidt, Utta, Tug, Suzan, Trinidad, Buena, Oehme, Felix, Yamac, Hatice, Wotzlaw, Christoph, Flamme, Ingo, Fandrey, Joachim
Published in The Journal of biological chemistry (14.11.2008)
Published in The Journal of biological chemistry (14.11.2008)
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Journal Article
Thermographic detection of turbulent flow separation on rotor blades of wind turbines in operation
Oehme, Felix, Gleichauf, Daniel, Suhr, Janick, Balaresque, Nicholas, Sorg, Michael, Fischer, Andreas
Published in Journal of wind engineering and industrial aerodynamics (01.07.2022)
Published in Journal of wind engineering and industrial aerodynamics (01.07.2022)
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Journal Article
Side‐by‐side comparability of batch and continuous downstream for the production of monoclonal antibodies
David, Laura, Schwan, Peter, Lobedann, Martin, Borchert, Sven‐Oliver, Budde, Bastian, Temming, Maike, Kuerschner, Mike, Alberti Aguilo, Francisca Maria, Baumarth, Kerstin, Thüte, Tobias, Maiser, Benjamin, Blank, Andreas, Kistler, Viktorija, Weber, Nils, Brandt, Heiko, Poggel, Martin, Kaiser, Klaus, Geisen, Karl, Oehme, Felix, Schembecker, Gerhard
Published in Biotechnology and bioengineering (01.04.2020)
Published in Biotechnology and bioengineering (01.04.2020)
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Journal Article
Pivotal Role for α1-Antichymotrypsin in Skin Repair
Hoffmann, Daniel C., Textoris, Christine, Oehme, Felix, Klaassen, Tobias, Goppelt, Andreas, Römer, Axel, Fugmann, Burkhard, Davidson, Jeffrey M., Werner, Sabine, Krieg, Thomas, Eming, Sabine A.
Published in The Journal of biological chemistry (19.08.2011)
Published in The Journal of biological chemistry (19.08.2011)
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Journal Article
Front Cover: Discovery of Molidustat (BAY 85‐3934): A Small‐Molecule Oral HIF‐Prolyl Hydroxylase (HIF‐PH) Inhibitor for the Treatment of Renal Anemia (ChemMedChem 10/2018)
Beck, Hartmut, Jeske, Mario, Thede, Kai, Stoll, Friederike, Flamme, Ingo, Akbaba, Metin, Ergüden, Jens‐Kerim, Karig, Gunter, Keldenich, Jörg, Oehme, Felix, Militzer, Hans‐Christian, Hartung, Ingo V., Thuss, Uwe
Published in ChemMedChem (23.05.2018)
Published in ChemMedChem (23.05.2018)
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Journal Article
Overexpression of PH-4, a novel putative proline 4-hydroxylase, modulates activity of hypoxia-inducible transcription factors
Oehme, Felix, Ellinghaus, Peter, Kolkhof, Peter, Smith, Timothy J, Ramakrishnan, Shyam, Hütter, Joachim, Schramm, Matthias, Flamme, Ingo
Published in Biochemical and biophysical research communications (16.08.2002)
Published in Biochemical and biophysical research communications (16.08.2002)
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Journal Article
The impact of N-nitrosomelatonin as nitric oxide donor in cell culture experiments
Berchner-Pfannschmidt, Utta, Tug, Suzan, Trinidad, Buena, Becker, Maria, Oehme, Felix, Flamme, Ingo, Fandrey, Joachim, Kirsch, Michael
Published in Journal of pineal research (01.11.2008)
Published in Journal of pineal research (01.11.2008)
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