TAK1 is a pivotal therapeutic target for tumor progression and bone destruction in myeloma
Teramachi, Jumpei, Tenshin, Hirofumi, Hiasa, Masahiro, Oda, Asuka, Bat-Erdene, Ariunzaya, Harada, Takeshi, Nakamura, Shingen, Ashtar, Mohannad, Shimizu, So, Iwasa, Masami, Sogabe, Kimiko, Oura, Masahiro, Fujii, Shiro, Kagawa, Kumiko, Miki, Hirokazu, Endo, Itsuro, Haneji, Tatsuji, Matsumoto, Toshio, Abe, Masahiro
Published in Haematologica (Roma) (01.05.2021)
Published in Haematologica (Roma) (01.05.2021)
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Tgf-Beta inhibition restores terminal osteoblast differentiation to suppress myeloma growth
Takeuchi, Kyoko, Abe, Masahiro, Hiasa, Masahiro, Oda, Asuka, Amou, Hiroe, Kido, Shinsuke, Harada, Takeshi, Tanaka, Osamu, Miki, Hirokazu, Nakamura, Shingen, Nakano, Ayako, Kagawa, Kumiko, Yata, Kenichiro, Ozaki, Shuji, Matsumoto, Toshio
Published in PloS one (25.03.2010)
Published in PloS one (25.03.2010)
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Mechanical unloading aggravates bone destruction and tumor expansion in myeloma
Tanimoto, Kotaro, Hiasa, Masahiro, Tenshin, Hirofumi, Teramachi, Jumpei, Oda, Asuka, Harada, Takeshi, Higa, Yoshiki, Sogabe, Kimiko, Oura, Masahiro, Sumitani, Ryohei, Hara, Tomoyo, Endo, Itsuro, Matsumoto, Toshio, Tanaka, Eiji, Abe, Masahiro
Published in Haematologica (Roma) (18.11.2021)
Published in Haematologica (Roma) (18.11.2021)
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Glycolysis inhibition inactivates ABC transporters to restore drug sensitivity in malignant cells
Nakano, Ayako, Tsuji, Daisuke, Miki, Hirokazu, Cui, Qu, El Sayed, Salah Mohamed, Ikegame, Akishige, Oda, Asuka, Amou, Hiroe, Nakamura, Shingen, Harada, Takeshi, Fujii, Shiro, Kagawa, Kumiko, Takeuchi, Kyoko, Sakai, Akira, Ozaki, Shuji, Okano, Kazuma, Nakamura, Takahiro, Itoh, Kohji, Matsumoto, Toshio, Abe, Masahiro
Published in PloS one (02.11.2011)
Published in PloS one (02.11.2011)
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Journal Article
Pim‐2 is a critical target for treatment of osteoclastogenesis enhanced in myeloma
Teramachi, Jumpei, Hiasa, Masahiro, Oda, Asuka, Harada, Takeshi, Nakamura, Shingen, Amachi, Ryota, Tenshin, Hirofumi, Iwasa, Masami, Fujii, Shiro, Kagawa, Kumiko, Miki, Hirokazu, Kurahashi, Kiyoe, Yoshida, Sumiko, Endo, Itsuro, Haneji, Tatsuji, Matsumoto, Toshio, Abe, Masahiro
Published in British journal of haematology (01.02.2018)
Published in British journal of haematology (01.02.2018)
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The Roles of ROS Generation in RANKL-Induced Osteoclastogenesis: Suppressive Effects of Febuxostat
Ashtar, Mohannad, Tenshin, Hirofumi, Teramachi, Jumpei, Bat-Erdene, Ariunzaya, Hiasa, Masahiro, Oda, Asuka, Tanimoto, Kotaro, Shimizu, So, Higa, Yoshiki, Harada, Takeshi, Oura, Masahiro, Sogabe, Kimiko, Nakamura, Shingen, Fujii, Shiro, Sumitani, Ryohei, Miki, Hirokazu, Udaka, Kengo, Takahashi, Mamiko, Kagawa, Kumiko, Endo, Itsuro, Tanaka, Eiji, Matsumoto, Toshio, Abe, Masahiro
Published in Cancers (09.04.2020)
Published in Cancers (09.04.2020)
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Journal Article
Myeloma Cell-Osteoclast Interaction Enhances Angiogenesis Together with Bone Resorption: A Role for Vascular Endothelial Cell Growth Factor and Osteopontin
TANAKA, Yoichi, ABE, Masahiro, MORIYAMA, Keiji, HASHIMOTO, Toshihiro, OZAKI, Shuji, MATSUMOTO, Toshio, HIASA, Masahiro, ODA, Asuka, AMOU, Hiroe, NAKANO, Ayako, TAKEUCHI, Kyoko, KITAZOE, Kenichi, KIDO, Shinsuke, INOUE, Daisuke
Published in Clinical cancer research (01.02.2007)
Published in Clinical cancer research (01.02.2007)
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Journal Article
The Xanthine Oxidase Inhibitor Febuxostat Suppresses Adipogenesis and Activates Nrf2
Higa, Yoshiki, Hiasa, Masahiro, Tenshin, Hirofumi, Nakaue, Emiko, Tanaka, Mariko, Kim, Sooha, Nakagawa, Motosumi, Shimizu, So, Tanimoto, Kotaro, Teramachi, Jumpei, Harada, Takeshi, Oda, Asuka, Oura, Masahiro, Sogabe, Kimiko, Hara, Tomoyo, Sumitani, Ryohei, Maruhashi, Tomoko, Yamagami, Hiroki, Endo, Itsuro, Matsumoto, Toshio, Tanaka, Eiji, Abe, Masahiro
Published in Antioxidants (05.01.2023)
Published in Antioxidants (05.01.2023)
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Journal Article
TGF‐β‐activated kinase‐1 inhibitor LL‐Z1640‐2 reduces joint inflammation and bone destruction in mouse models of rheumatoid arthritis by inhibiting NLRP3 inflammasome, TACE, TNF‐α and RANKL expression
Tenshin, Hirofumi, Teramachi, Jumpei, Ashtar, Mohannad, Hiasa, Masahiro, Inoue, Yusuke, Oda, Asuka, Tanimoto, Kotaro, Shimizu, So, Higa, Yoshiki, Harada, Takeshi, Oura, Masahiro, Sogabe, Kimiko, Hara, Tomoyo, Sumitani, Ryohei, Maruhashi, Tomoko, Sebe, Mayu, Tsutsumi, Rie, Sakaue, Hiroshi, Endo, Itsuro, Matsumoto, Toshio, Tanaka, Eiji, Abe, Masahiro
Published in Clinical & translational immunology (2022)
Published in Clinical & translational immunology (2022)
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Journal Article
Association of Th1 and Th2 cytokines with transient inflammatory reaction during lenalidomide plus dexamethasone therapy in multiple myeloma
Harada, Takeshi, Ozaki, Shuji, Oda, Asuka, Fujii, Shiro, Nakamura, Shingen, Miki, Hirokazu, Kagawa, Kumiko, Takeuchi, Kyoko, Matsumoto, Toshio, Abe, Masahiro
Published in International journal of hematology (01.06.2013)
Published in International journal of hematology (01.06.2013)
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Journal Article
Therapeutic efficacy of the resorcylic acid lactone LL‐Z1640‐2 for adult T‐cell leukaemia/lymphoma
Oura, Masahiro, Harada, Takeshi, Oda, Asuka, Teramachi, Jumpei, Nakayama, Atsushi, Sumitani, Ryohei, Inoue, Yusuke, Maeda, Yusaku, Sogabe, Kimiko, Maruhashi, Tomoko, Takahashi, Mamiko, Fujii, Shiro, Nakamura, Shingen, Miki, Hirokazu, Nakamura, Masafumi, Hara, Tomoyo, Yamagami, Hiroki, Kurahashi, Kiyoe, Endo, Itsuro, Hasegawa, Hiroo, Fujiwara, Hiroshi, Abe, Masahiro
Published in EJHaem (01.08.2023)
Published in EJHaem (01.08.2023)
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Journal Article
Combination with a defucosylated anti-HM1.24 monoclonal antibody plus lenalidomide induces marked ADCC against myeloma cells and their progenitors
Harada, Takeshi, Ozaki, Shuji, Oda, Asuka, Tsuji, Daisuke, Ikegame, Akishige, Iwasa, Masami, Udaka, Kengo, Fujii, Shiro, Nakamura, Shingen, Miki, Hirokazu, Kagawa, Kumiko, Kuroda, Yoshiaki, Kawai, Shigeto, Itoh, Kohji, Yamada-Okabe, Hisafumi, Matsumoto, Toshio, Abe, Masahiro
Published in PloS one (26.12.2013)
Published in PloS one (26.12.2013)
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Journal Article
A vicious cycle between acid sensing and survival signaling in myeloma cells: acid-induced epigenetic alteration
Amachi, Ryota, Hiasa, Masahiro, Teramachi, Jumpei, Harada, Takeshi, Oda, Asuka, Nakamura, Shingen, Hanson, Derek, Watanabe, Keiichiro, Fujii, Shiro, Miki, Hirokazu, Kagawa, Kumiko, Iwasa, Masami, Endo, Itsuro, Kondo, Takeshi, Yoshida, Sumiko, Aihara, Ken-Ichi, Kurahashi, Kiyoe, Kuroda, Yoshiaki, Horikawa, Hideaki, Tanaka, Eiji, Matsumoto, Toshio, Abe, Masahiro
Published in Oncotarget (25.10.2016)
Published in Oncotarget (25.10.2016)
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Journal Article
TAK1 inhibition effectively suppresses NLRP3 inflammasome-mediated inflammation and osteoclastic bone resorption in rheumatoid arthritis
Tenshin, Hirofumi, Teramachi, Jumpei, Hiasa, Masahiro, Oda, Asuka, Harada, Takeshi, Oura, Masahiro, Sogabe, Kimiko, Ashtar, Mohannad, Tanimoto, Kotaro, Shimizu, So, Higa, Yoshiki, Tanaka, Eiji, Matsumoto, Toshio, Abe, Masahiro
Published in Bone Reports (01.10.2020)
Published in Bone Reports (01.10.2020)
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Journal Article
Mechanical unloading enhances bone destruction and tumor expansion in multiple myeloma: Critical roles of osteocytic RANKL induction
Tanimoto, Kotaro, Hiasa, Masahiro, Tenshin, Hirofumi, Teramachi, Jumpei, Oda, Asuka, Harada, Takeshi, Ashter, Mohannad, Sogabe, Kimiko, Oura, Masahiro, Endo, Itsuro, Matsumoto, Toshio, Tanaka, Eiji, Abe, Masahiro
Published in Bone Reports (01.10.2020)
Published in Bone Reports (01.10.2020)
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Journal Article
The anti-SLAMF7 elotuzumab enhances ADCC activity with Th1-like γδT cells towards osteoclasts and myeloma cells
Tenshin, Hirofumi, Harada, Takeshi, Inoue, Yusuke, Teramachi, Jumpei, Hiasa, Masahiro, Oda, Asuka, Tanimoto, Kotaro, Shimizu, So, Higa, Yoshiki, Oura, Masahiro, Sogabe, Kimiko, Hara, Tomoyo, Maruhashi, Tomoko, Endo, Itsuro, Matsumoto, Toshio, Tanaka, Eiji, Abe, Masahiro
Published in Bone Reports (01.04.2021)
Published in Bone Reports (01.04.2021)
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Journal Article
Inhibition of TACE activity enhances the susceptibility of myeloma cells to TRAIL
Kagawa, Kumiko, Nakano, Ayako, Miki, Hirokazu, Oda, Asuka, Amou, Hiroe, Takeuchi, Kyoko, Nakamura, Shingen, Harada, Takeshi, Fujii, Shiro, Yata, Kenichiro, Ozaki, Shuji, Matsumoto, Toshio, Abe, Masahiro
Published in PloS one (28.02.2012)
Published in PloS one (28.02.2012)
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Journal Article
Reveromycin A, a novel acid-seeking agent, ameliorates bone destruction and tumor growth in multiple myeloma
Watanabe, Keiichiro, Bat-Erdene, Ariunzaya, Tenshin, Hirofumi, Cui, Qu, Teramachi, Jumpei, Hiasa, Masahiro, Oda, Asuka, Harada, Takeshi, Miki, Hirokazu, Sogabe, Kimiko, Oura, Masahiro, Sumitani, Ryohei, Mitsui, Yukari, Endo, Itsuro, Tanaka, Eiji, Kawatani, Makoto, Osada, Hiroyuki, Matsumoto, Toshio, Abe, Masahiro
Published in Haematologica (Roma) (01.04.2021)
Published in Haematologica (Roma) (01.04.2021)
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Journal Article
Activating transcription factor 4, an ER stress mediator, is required for, but excessive ER stress suppresses osteoblastogenesis by bortezomib
Nakamura, Shingen, Miki, Hirokazu, Kido, Shinsuke, Nakano, Ayako, Hiasa, Masahiro, Oda, Asuka, Amou, Hiroe, Watanabe, Keiichiro, Harada, Takeshi, Fujii, Shiro, Takeuchi, Kyoko, Kagawa, Kumiko, Ozaki, Shuji, Matsumoto, Toshio, Abe, Masahiro
Published in International journal of hematology (01.07.2013)
Published in International journal of hematology (01.07.2013)
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