Ubiquitin-specific protease 21 stabilizes BRCA2 to control DNA repair and tumor growth
Liu, Jinping, Kruswick, Alex, Dang, Hien, Tran, Andy D., Kwon, So Mee, Wang, Xin Wei, Oberdoerffer, Philipp
Published in Nature communications (26.07.2017)
Published in Nature communications (26.07.2017)
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Journal Article
RNA: a double-edged sword in genome maintenance
Zong, Dali, Oberdoerffer, Philipp, Batista, Pedro J., Nussenzweig, André
Published in Nature reviews. Genetics (01.11.2020)
Published in Nature reviews. Genetics (01.11.2020)
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Journal Article
A Macrohistone Variant Links Dynamic Chromatin Compaction to BRCA1-Dependent Genome Maintenance
Khurana, Simran, Kruhlak, Michael J., Kim, Jeongkyu, Tran, Andy D., Liu, Jinping, Nyswaner, Katherine, Shi, Lei, Jailwala, Parthav, Sung, Myong-Hee, Hakim, Ofir, Oberdoerffer, Philipp
Published in Cell reports (Cambridge) (21.08.2014)
Published in Cell reports (Cambridge) (21.08.2014)
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Journal Article
Replication Stress Shapes a Protective Chromatin Environment across Fragile Genomic Regions
Kim, Jeongkyu, Sturgill, David, Sebastian, Robin, Khurana, Simran, Tran, Andy D., Edwards, Garrett B., Kruswick, Alex, Burkett, Sandra, Hosogane, Eri K., Hannon, William W., Weyemi, Urbain, Bonner, William M., Luger, Karolin, Oberdoerffer, Philipp
Published in Molecular cell (04.01.2018)
Published in Molecular cell (04.01.2018)
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Journal Article
SIRT1 Redistribution on Chromatin Promotes Genomic Stability but Alters Gene Expression during Aging
Oberdoerffer, Philipp, Michan, Shaday, McVay, Michael, Mostoslavsky, Raul, Vann, James, Park, Sang-Kyu, Hartlerode, Andrea, Stegmuller, Judith, Hafner, Angela, Loerch, Patrick, Wright, Sarah M., Mills, Kevin D., Bonni, Azad, Yankner, Bruce A., Scully, Ralph, Prolla, Tomas A., Alt, Frederick W., Sinclair, David A.
Published in Cell (28.11.2008)
Published in Cell (28.11.2008)
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Journal Article
The SIRT1 deacetylase suppresses intestinal tumorigenesis and colon cancer growth
Firestein, Ron, Blander, Gil, Michan, Shaday, Oberdoerffer, Philipp, Ogino, Shuji, Campbell, Jennifer, Bhimavarapu, Anupama, Luikenhuis, Sandra, de Cabo, Rafael, Fuchs, Charles, Hahn, William C, Guarente, Leonard P, Sinclair, David A
Published in PloS one (16.04.2008)
Published in PloS one (16.04.2008)
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Journal Article
The macroH2A1.2 histone variant links ATRX loss to alternative telomere lengthening
Kim, Jeongkyu, Sun, Chongkui, Tran, Andy D., Chin, Pei-Ju, Ruiz, Penelope D., Wang, Kun, Gibbons, Richard J., Gamble, Matthew J., Liu, Yie, Oberdoerffer, Philipp
Published in Nature structural & molecular biology (01.03.2019)
Published in Nature structural & molecular biology (01.03.2019)
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Journal Article
DNA damage, chromatin, and transcription: the trinity of aging
Burgess, Rebecca C, Misteli, Tom, Oberdoerffer, Philipp
Published in Current opinion in cell biology (01.12.2012)
Published in Current opinion in cell biology (01.12.2012)
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Journal Article
SIRT1 Activation Disrupts Maintenance of Myelodysplastic Syndrome Stem and Progenitor Cells by Restoring TET2 Function
Sun, Jie, He, Xin, Zhu, Yinghui, Ding, Zonghui, Dong, Haojie, Feng, Yimei, Du, Juan, Wang, Hanying, Wu, Xiwei, Zhang, Lei, Yu, Xiaochun, Lin, Allen, McDonald, Tinisha, Zhao, Dandan, Wu, Herman, Hua, Wei-Kai, Zhang, Bin, Feng, Lifeng, Tohyama, Kaoru, Bhatia, Ravi, Oberdoerffer, Philipp, Chung, Yang Jo, Aplan, Peter D., Boultwood, Jacqueline, Pellagatti, Andrea, Khaled, Samer, Kortylewski, Marcin, Pichiorri, Flavia, Kuo, Ya-Huei, Carlesso, Nadia, Marcucci, Guido, Jin, Hongchuan, Li, Ling
Published in Cell stem cell (06.09.2018)
Published in Cell stem cell (06.09.2018)
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Journal Article
Encounters in Three Dimensions: How Nuclear Topology Shapes Genome Integrity
Sebastian, Robin, Aladjem, Mirit I., Oberdoerffer, Philipp
Published in Frontiers in genetics (21.10.2021)
Published in Frontiers in genetics (21.10.2021)
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Journal Article
Sirt1 ablation promotes stress-induced loss of epigenetic and genomic hematopoietic stem and progenitor cell maintenance
Singh, Satyendra K, Williams, Carrie A, Klarmann, Kimberly, Burkett, Sandra S, Keller, Jonathan R, Oberdoerffer, Philipp
Published in The Journal of experimental medicine (06.05.2013)
Published in The Journal of experimental medicine (06.05.2013)
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Journal Article
CTCF-promoted RNA polymerase II pausing links DNA methylation to splicing
SHUKLA, Sanjeev, KAVAK, Ersen, GREGORY, Melissa, IMASHIMIZU, Masahiko, SHUTINOSKI, Bojan, KASHLEV, Mikhail, OBERDOERFFER, Philipp, SANDBERG, Rickard, OBERDOERFFER, Shalini
Published in Nature (London) (03.11.2011)
Published in Nature (London) (03.11.2011)
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Journal Article
The histone variant macroH2A1 is a splicing-modulated caretaker of genome integrity and tumor growth
Kim, Jeongkyu, Oberdoerffer, Philipp, Khurana, Simran
Published in Molecular & cellular oncology (04.05.2018)
Published in Molecular & cellular oncology (04.05.2018)
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Journal Article
AKTing on R Loops Makes for an ATRactive Target in Ovarian Cancer Therapy
Ramanarayanan, Vijayalalitha, Oberdoerffer, Philipp
Published in Cancer research (Chicago, Ill.) (15.03.2024)
Published in Cancer research (Chicago, Ill.) (15.03.2024)
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Journal Article
Efficiency of RNA Interference in the Mouse Hematopoietic System Varies between Cell Types and Developmental Stages
Oberdoerffer, Philipp, Kanellopoulou, Chryssa, Heissmeyer, Vigo, Paeper, Corinna, Borowski, Christine, Aifantis, Iannis, Rao, Anjana, Rajewsky, Klaus
Published in Molecular and Cellular Biology (01.05.2005)
Published in Molecular and Cellular Biology (01.05.2005)
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Journal Article
Histone H2A variants: Diversifying chromatin to ensure genome integrity
Oberdoerffer, Philipp, Miller, Kyle M.
Published in Seminars in cell & developmental biology (15.02.2023)
Published in Seminars in cell & developmental biology (15.02.2023)
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