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Telomeres: protecting chromosomes against genome instability
O'Sullivan, Roderick J., Karlseder, Jan
Published in Nature reviews. Molecular cell biology (01.03.2010)
Published in Nature reviews. Molecular cell biology (01.03.2010)
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Journal Article
Mechanisms of Alternative Lengthening of Telomeres
O'Sullivan, Roderick J., Greenberg, Roger A.
Published in Cold Spring Harbor perspectives in biology (01.01.2025)
Published in Cold Spring Harbor perspectives in biology (01.01.2025)
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Journal Article
Genome rearrangements associated with aberrant telomere maintenance
Bhargava, Ragini, Fischer, Matthias, O’Sullivan, Roderick J
Published in Current opinion in genetics & development (01.02.2020)
Published in Current opinion in genetics & development (01.02.2020)
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Journal Article
Modular antibodies reveal DNA damage-induced mono-ADP-ribosylation as a second wave of PARP1 signaling
Longarini, Edoardo José, Dauben, Helen, Locatelli, Carolina, Wondisford, Anne R., Smith, Rebecca, Muench, Charlotte, Kolvenbach, Andreas, Lynskey, Michelle Lee, Pope, Alexis, Bonfiglio, Juan José, Jurado, Eva Pinto, Fajka-Boja, Roberta, Colby, Thomas, Schuller, Marion, Ahel, Ivan, Timinszky, Gyula, O’Sullivan, Roderick J., Huet, Sébastien, Matic, Ivan
Published in Molecular cell (18.05.2023)
Published in Molecular cell (18.05.2023)
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Journal Article
New twists to the ALTernative endings at telomeres
Bhargava, Ragini, Lynskey, Michelle Lee, O’Sullivan, Roderick J.
Published in DNA repair (01.07.2022)
Published in DNA repair (01.07.2022)
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Journal Article
Oligoadenylate-Synthetase-Family Protein OASL Inhibits Activity of the DNA Sensor cGAS during DNA Virus Infection to Limit Interferon Production
Ghosh, Arundhati, Shao, Lulu, Sampath, Padmavathi, Zhao, Baoyu, Patel, Nidhi V., Zhu, Jianzhong, Behl, Bharat, Parise, Robert A., Beumer, Jan H., O’Sullivan, Roderick J., DeLuca, Neal A., Thorne, Stephen H., Rathinam, Vijay A.K., Li, Pingwei, Sarkar, Saumendra N.
Published in Immunity (Cambridge, Mass.) (15.01.2019)
Published in Immunity (Cambridge, Mass.) (15.01.2019)
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Journal Article
TERRA-LSD1 phase separation promotes R-loop formation for telomere maintenance in ALT cancer cells
Xu, Meng, Senanayaka, Dulmi, Zhao, Rongwei, Chigumira, Tafadzwa, Tripathi, Astha, Tones, Jason, Lackner, Rachel M., Wondisford, Anne R., Moneysmith, Laurel N., Hirschi, Alexander, Craig, Sara, Alishiri, Sahar, O’Sullivan, Roderick J., Chenoweth, David M., Reiter, Nicholas J., Zhang, Huaiying
Published in Nature communications (09.03.2024)
Published in Nature communications (09.03.2024)
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Journal Article
Rapid induction of alternative lengthening of telomeres by depletion of the histone chaperone ASF1
O'Sullivan, Roderick J, Arnoult, Nausica, Lackner, Daniel H, Oganesian, Liana, Haggblom, Candy, Corpet, Armelle, Almouzni, Genevieve, Karlseder, Jan
Published in Nature structural & molecular biology (01.02.2014)
Published in Nature structural & molecular biology (01.02.2014)
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Journal Article
Suv39h-Dependent H3K9me3 Marks Intact Retrotransposons and Silences LINE Elements in Mouse Embryonic Stem Cells
Bulut-Karslioglu, Aydan, De La Rosa-Velázquez, Inti A., Ramirez, Fidel, Barenboim, Maxim, Onishi-Seebacher, Megumi, Arand, Julia, Galán, Carmen, Winter, Georg E., Engist, Bettina, Gerle, Borbala, O’Sullivan, Roderick J., Martens, Joost H.A., Walter, Jörn, Manke, Thomas, Lachner, Monika, Jenuwein, Thomas
Published in Molecular cell (17.07.2014)
Published in Molecular cell (17.07.2014)
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Journal Article
Unrestrained poly-ADP-ribosylation provides insights into chromatin regulation and human disease
Prokhorova, Evgeniia, Agnew, Thomas, Wondisford, Anne R., Tellier, Michael, Kaminski, Nicole, Beijer, Danique, Holder, James, Groslambert, Josephine, Suskiewicz, Marcin J., Zhu, Kang, Reber, Julia M., Krassnig, Sarah C., Palazzo, Luca, Murphy, Shona, Nielsen, Michael L., Mangerich, Aswin, Ahel, Dragana, Baets, Jonathan, O’Sullivan, Roderick J., Ahel, Ivan
Published in Molecular cell (17.06.2021)
Published in Molecular cell (17.06.2021)
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Journal Article
Proteomic Profiling Reveals a Specific Role for Translesion DNA Polymerase η in the Alternative Lengthening of Telomeres
Garcia-Exposito, Laura, Bournique, Elodie, Bergoglio, Valérie, Bose, Arindam, Barroso-Gonzalez, Jonathan, Zhang, Sufang, Roncaioli, Justin L., Lee, Marietta, Wallace, Callen T., Watkins, Simon C., Opresko, Patricia L., Hoffmann, Jean-Sébastien, O’Sullivan, Roderick J.
Published in Cell reports (Cambridge) (08.11.2016)
Published in Cell reports (Cambridge) (08.11.2016)
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Journal Article
Regulation of ALT-associated homology-directed repair by polyADP-ribosylation
Hoang, Song My, Kaminski, Nicole, Bhargava, Ragini, Barroso-González, Jonathan, Lynskey, Michelle L., García-Expósito, Laura, Roncaioli, Justin L., Wondisford, Anne R., Wallace, Callen T., Watkins, Simon C., James, Dominic I., Waddell, Ian D., Ogilvie, Donald, Smith, Kate M., da Veiga Leprevost, Felipe, Mellacharevu, Dattatreya, Nesvizhskii, Alexey I., Li, Jianfeng, Ray-Gallet, Dominique, Sobol, Robert W., Almouzni, Genevieve, O’Sullivan, Roderick J.
Published in Nature structural & molecular biology (01.12.2020)
Published in Nature structural & molecular biology (01.12.2020)
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Journal Article
TERRA and hnRNPA1 orchestrate an RPA-to-POT1 switch on telomeric single-stranded DNA
Flynn, Rachel Litman, Centore, Richard C., O’Sullivan, Roderick J., Rai, Rekha, Tse, Alice, Songyang, Zhou, Chang, Sandy, Karlseder, Jan, Zou, Lee
Published in Nature (London) (24.03.2011)
Published in Nature (London) (24.03.2011)
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Journal Article
A mechanistic classification of clinical phenotypes in neuroblastoma
Ackermann, Sandra, Cartolano, Maria, Hero, Barbara, Welte, Anne, Kahlert, Yvonne, Roderwieser, Andrea, Bartenhagen, Christoph, Walter, Esther, Gecht, Judith, Kerschke, Laura, Volland, Ruth, Menon, Roopika, Heuckmann, Johannes M., Gartlgruber, Moritz, Hartlieb, Sabine, Henrich, Kai-Oliver, Okonechnikov, Konstantin, Altmüller, Janine, Nürnberg, Peter, Lefever, Steve, de Wilde, Bram, Sand, Frederik, Ikram, Fakhera, Rosswog, Carolina, Fischer, Janina, Theissen, Jessica, Hertwig, Falk, Singhi, Aatur D., Simon, Thorsten, Vogel, Wenzel, Perner, Sven, Krug, Barbara, Schmidt, Matthias, Rahmann, Sven, Achter, Viktor, Lang, Ulrich, Vokuhl, Christian, Ortmann, Monika, Büttner, Reinhard, Eggert, Angelika, Speleman, Frank, O’Sullivan, Roderick J., Thomas, Roman K., Berthold, Frank, Vandesompele, Jo, Schramm, Alexander, Westermann, Frank, Schulte, Johannes H., Peifer, Martin, Fischer, Matthias
Published in Science (American Association for the Advancement of Science) (07.12.2018)
Published in Science (American Association for the Advancement of Science) (07.12.2018)
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Journal Article
The great unravelling: chromatin as a modulator of the aging process
O'Sullivan, Roderick J., Karlseder, Jan
Published in Trends in biochemical sciences (Amsterdam. Regular ed.) (01.11.2012)
Published in Trends in biochemical sciences (Amsterdam. Regular ed.) (01.11.2012)
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Journal Article
Telomerase activation by genomic rearrangements in high-risk neuroblastoma
Peifer, Martin, Hertwig, Falk, Roels, Frederik, Dreidax, Daniel, Gartlgruber, Moritz, Menon, Roopika, Krämer, Andrea, Roncaioli, Justin L., Sand, Frederik, Heuckmann, Johannes M., Ikram, Fakhera, Schmidt, Rene, Ackermann, Sandra, Engesser, Anne, Kahlert, Yvonne, Vogel, Wenzel, Altmüller, Janine, Nürnberg, Peter, Thierry-Mieg, Jean, Thierry-Mieg, Danielle, Mariappan, Aruljothi, Heynck, Stefanie, Mariotti, Erika, Henrich, Kai-Oliver, Gloeckner, Christian, Bosco, Graziella, Leuschner, Ivo, Schweiger, Michal R., Savelyeva, Larissa, Watkins, Simon C., Shao, Chunxuan, Bell, Emma, Höfer, Thomas, Achter, Viktor, Lang, Ulrich, Theissen, Jessica, Volland, Ruth, Saadati, Maral, Eggert, Angelika, de Wilde, Bram, Berthold, Frank, Peng, Zhiyu, Zhao, Chen, Shi, Leming, Ortmann, Monika, Büttner, Reinhard, Perner, Sven, Hero, Barbara, Schramm, Alexander, Schulte, Johannes H., Herrmann, Carl, O’Sullivan, Roderick J., Westermann, Frank, Thomas, Roman K., Fischer, Matthias
Published in Nature (London) (29.10.2015)
Published in Nature (London) (29.10.2015)
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Journal Article
Deregulated DNA ADP-ribosylation impairs telomere replication
Wondisford, Anne R., Lee, Junyeop, Lu, Robert, Schuller, Marion, Groslambert, Josephine, Bhargava, Ragini, Schamus-Haynes, Sandra, Cespedes, Leyneir C., Opresko, Patricia L., Pickett, Hilda A., Min, Jaewon, Ahel, Ivan, O’Sullivan, Roderick J.
Published in Nature structural & molecular biology (01.05.2024)
Published in Nature structural & molecular biology (01.05.2024)
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Journal Article
Extrachromosomal telomere DNA derived from excessive strand displacements
Lee, Junyeop, Lee, Jina, Sohn, Eric J., Taglialatela, Angelo, O’Sullivan, Roderick J., Ciccia, Alberto, Min, Jaewon
Published in Proceedings of the National Academy of Sciences - PNAS (07.05.2024)
Published in Proceedings of the National Academy of Sciences - PNAS (07.05.2024)
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Journal Article
Alternative Lengthening of Telomeres and Loss of DAXX/ATRX Expression Predicts Metastatic Disease and Poor Survival in Patients with Pancreatic Neuroendocrine Tumors
Singhi, Aatur D., Liu, Ta-Chiang, Roncaioli, Justin L., Cao, Dengfeng, Zeh, Herbert J., Zureikat, Amer H., Tsung, Allan, Marsh, J. Wallis, Lee, Kenneth K., Hogg, Melissa E., Bahary, Nathan, Brand, Randall E., McGrath, Kevin M., Slivka, Adam, Cressman, Kristi L., Fuhrer, Kimberly, O'Sullivan, Roderick J.
Published in Clinical cancer research (15.01.2017)
Published in Clinical cancer research (15.01.2017)
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