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Inhibition mechanism of SARS-CoV-2 main protease by ebselen and its derivatives
Amporndanai, Kangsa, Meng, Xiaoli, Shang, Weijuan, Jin, Zhenmig, Rogers, Michael, Zhao, Yao, Rao, Zihe, Liu, Zhi-Jie, Yang, Haitao, Zhang, Leike, O’Neill, Paul M., Samar Hasnain, S.
Published in Nature communications (24.05.2021)
Published in Nature communications (24.05.2021)
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Synthesis, insecticidal activity, resistance, photodegradation and toxicity of pyrethroids (A review)
Zhu, Qiuyan, Yang, Yang, Zhong, Yingying, Lao, Zhiting, O’Neill, Paul, Hong, David, Zhang, Kun, Zhao, Suqing
Published in Chemosphere (Oxford) (01.09.2020)
Published in Chemosphere (Oxford) (01.09.2020)
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Artemisinin activity-based probes identify multiple molecular targets within the asexual stage of the malaria parasites Plasmodium falciparum 3D7
Ismail, Hanafy M., Barton, Victoria, Phanchana, Matthew, Charoensutthivarakul, Sitthivut, Wong, Michael H. L., Hemingway, Janet, Biagini, Giancarlo A., O’Neill, Paul M., Ward, Stephen A.
Published in Proceedings of the National Academy of Sciences - PNAS (23.02.2016)
Published in Proceedings of the National Academy of Sciences - PNAS (23.02.2016)
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Antimalarial activity of primaquine operates via a two-step biochemical relay
Camarda, Grazia, Jirawatcharadech, Piyaporn, Priestley, Richard S., Saif, Ahmed, March, Sandra, Wong, Michael H. L., Leung, Suet, Miller, Alex B., Baker, David A., Alano, Pietro, Paine, Mark J. I., Bhatia, Sangeeta N., O’Neill, Paul M., Ward, Stephen A., Biagini, Giancarlo A.
Published in Nature communications (19.07.2019)
Published in Nature communications (19.07.2019)
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The cysteine-reactive small molecule ebselen facilitates effective SOD1 maturation
Capper, Michael J., Wright, Gareth S. A., Barbieri, Letizia, Luchinat, Enrico, Mercatelli, Eleonora, McAlary, Luke, Yerbury, Justin J., O’Neill, Paul M., Antonyuk, Svetlana V., Banci, Lucia, Hasnain, S. Samar
Published in Nature communications (27.04.2018)
Published in Nature communications (27.04.2018)
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Ebselen analogues delay disease onset and its course in fALS by on-target SOD-1 engagement
Watanabe, Seiji, Amporndanai, Kangsa, Awais, Raheela, Latham, Caroline, Awais, Muhammad, O’Neill, Paul M., Yamanaka, Koji, Hasnain, S. Samar
Published in Scientific reports (27.05.2024)
Published in Scientific reports (27.05.2024)
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Optimised protocol for monitoring SARS-CoV-2 in wastewater using reverse complement PCR-based whole-genome sequencing
Child, Harry T., O’Neill, Paul A., Moore, Karen, Rowe, William, Denise, Hubert, Bass, David, Wade, Matthew J., Loose, Matt, Paterson, Steve, van Aerle, Ronny, Jeffries, Aaron R.
Published in PloS one (14.04.2023)
Published in PloS one (14.04.2023)
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Prioritization of Anti‐SARS‐Cov‐2 Drug Repurposing Opportunities Based on Plasma and Target Site Concentrations Derived from their Established Human Pharmacokinetics
Arshad, Usman, Pertinez, Henry, Box, Helen, Tatham, Lee, Rajoli, Rajith K. R., Curley, Paul, Neary, Megan, Sharp, Joanne, Liptrott, Neill J., Valentijn, Anthony, David, Christopher, Rannard, Steve P., O’Neill, Paul M., Aljayyoussi, Ghaith, Pennington, Shaun H., Ward, Stephen A., Hill, Andrew, Back, David J., Khoo, Saye H., Bray, Patrick G., Biagini, Giancarlo A., Owen, Andrew
Published in Clinical pharmacology and therapeutics (01.10.2020)
Published in Clinical pharmacology and therapeutics (01.10.2020)
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Phosphinic acids: current status and potential for drug discovery
Abdou, Moaz M., O’Neill, Paul M., Amigues, Eric, Matziari, Magdalini
Published in Drug discovery today (01.03.2019)
Published in Drug discovery today (01.03.2019)
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Anti-Wolbachia drugs for filariasis
Johnston, Kelly L., Hong, W. David, Turner, Joseph D., O’Neill, Paul M., Ward, Stephen A., Taylor, Mark J.
Published in Trends in parasitology (01.12.2021)
Published in Trends in parasitology (01.12.2021)
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Revisiting the Structure and Chemistry of 3(5)-Substituted Pyrazoles
Secrieru, Alina, O’Neill, Paul Michael, Cristiano, Maria Lurdes Santos
Published in Molecules (Basel, Switzerland) (20.12.2019)
Published in Molecules (Basel, Switzerland) (20.12.2019)
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Seeing the same thing differently: Mechanisms that contribute to assessor differences in directly-observed performance assessments
Yeates, Peter, O’Neill, Paul, Mann, Karen, Eva, Kevin
Published in Advances in health sciences education : theory and practice (01.08.2013)
Published in Advances in health sciences education : theory and practice (01.08.2013)
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Synthesis of Non-symmetrical Dispiro-1,2,4,5-Tetraoxanes and Dispiro-1,2,4-Trioxanes Catalyzed by Silica Sulfuric Acid
Amado, Patrícia S. M, Frija, Luís M. T, Coelho, Jaime A. S, O’Neill, Paul M, Cristiano, Maria L. S
Published in Journal of organic chemistry (06.08.2021)
Published in Journal of organic chemistry (06.08.2021)
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