Beneficial effects of the novel cholecystokinin agonist (pGlu-Gln)-CCK-8 in mouse models of obesity/diabetes
Irwin, N., Frizelle, P., Montgomery, I. A., Moffett, R. C., O’Harte, F. P. M., Flatt, P. R.
Published in Diabetologia (01.10.2012)
Published in Diabetologia (01.10.2012)
Get full text
Journal Article
Early administration of the glucose-dependent insulinotropic polypeptide receptor antagonist (Pro³)GIP prevents the development of diabetes and related metabolic abnormalities associated with genetically inherited obesity in ob/ob mice
Irwin, N, McClean, P. L, O'Harte, F. P. M, Gault, V. A, Harriott, P, Flatt, P. R
Published in Diabetologia (01.07.2007)
Published in Diabetologia (01.07.2007)
Get full text
Journal Article
Inhibition of dipeptidyl peptidase IV activity by oral metformin in Type 2 diabetes
Lindsay, J. R., Duffy, N. A., McKillop, A. M., Ardill, J., O'Harte, F. P. M., Flatt, P. R., Bell, P. M.
Published in Diabetic medicine (01.05.2005)
Published in Diabetic medicine (01.05.2005)
Get full text
Journal Article
Glucagon receptor antagonist and GIP agonist combination for diet-induced obese mice
McShane, L M, Irwin, N, O’Flynn, D, Franklin, Z J, Hewage, C M, O’Harte, F P M
Published in Journal of endocrinology (01.06.2016)
Published in Journal of endocrinology (01.06.2016)
Get full text
Journal Article
Macroalgal protein hydrolysates from Palmaria palmata influence the ‘incretin effect’ in vitro via DPP-4 inhibition and upregulation of insulin, GLP-1 and GIP secretion
McLaughlin, C. M., Harnedy-Rothwell, P. A., Lafferty, R. A., Sharkey, S., Parthsarathy, V., Allsopp, P. J., McSorley, E. M., FitzGerald, R. J., O’Harte, F. P. M.
Published in European journal of nutrition (01.12.2021)
Published in European journal of nutrition (01.12.2021)
Get full text
Journal Article
Effects of sub-chronic exposure to naturally occurring N-terminally truncated metabolites of glucose-dependent insulinotrophic polypeptide (GIP) and glucagon-like peptide-1 (GLP-1), GIP(3–42) and GLP-1(9–36)amide, on insulin secretion and glucose homeostasis in ob/ob mice
Parker, J C, Lavery, K S, Irwin, N, Green, B D, Greer, B, Harriott, P, O’Harte, F P M, Gault, V A, Flatt, P R
Published in Journal of endocrinology (01.10.2006)
Published in Journal of endocrinology (01.10.2006)
Get full text
Journal Article
Investigation of the effect of oral metformin on dipeptidylpeptidase-4 (DPP-4) activity in Type 2 diabetes
Cuthbertson, J., Patterson, S., O'Harte, F. P. M., Bell, P. M.
Published in Diabetic medicine (01.06.2009)
Published in Diabetic medicine (01.06.2009)
Get full text
Journal Article
Comparison of the independent and combined metabolic effects of subchronic modulation of CCK and GIP receptor action in obesity-related diabetes
Irwin, N, Montgomery, I A, O'Harte, F P M, Frizelle, P, Flatt, P R
Published in International Journal of Obesity (01.08.2013)
Published in International Journal of Obesity (01.08.2013)
Get full text
Journal Article
Chronic treatment with exendin(9–39)amide indicates a minor role for endogenous glucagon-like peptide-1 in metabolic abnormalities of obesity-related diabetes in ob/ob mice
Green, B D, Irwin, N, Gault, V A, Bailey, C J, O’Harte, F P M, Flatt, P R
Published in Journal of endocrinology (01.05.2005)
Published in Journal of endocrinology (01.05.2005)
Get full text
Journal Article
Effects of the novel (Pro3)GIP antagonist and exendin(9-39)amide on GIP- and GLP-1-induced cyclic AMP generation, insulin secretion and postprandial insulin release in obese diabetic (ob/ob) mice: evidence that GIP is the major physiological incretin
GAULT, V. A, O'HARTE, F. P. M, HARRIOTT, P, MOONEY, M. H, GREEN, B. D, FLATT, P. R
Published in Diabetologia (01.02.2003)
Published in Diabetologia (01.02.2003)
Get full text
Journal Article
Apelin-13 analogues show potent in vitro and in vivo insulinotropic and glucose lowering actions
O’Harte, F.P.M., Parthsarathy, V., Hogg, C., Flatt, P.R.
Published in Peptides (New York, N.Y. : 1980) (01.02.2018)
Published in Peptides (New York, N.Y. : 1980) (01.02.2018)
Get full text
Journal Article
Novel dual agonist peptide analogues derived from dogfish glucagon show promising in vitro insulin releasing actions and antihyperglycaemic activity in mice
O'Harte, F.P.M., Ng, M.T., Lynch, A.M., Conlon, J.M., Flatt, P.R.
Published in Molecular and cellular endocrinology (15.08.2016)
Published in Molecular and cellular endocrinology (15.08.2016)
Get full text
Journal Article
Characterization of insulin glycation in insulin-secreting cells maintained in tissue culture
Y H A Abdel-Wahab, F P M O'Harte, C R Barnett, P R Flatt
Published in Journal of endocrinology (01.01.1997)
Published in Journal of endocrinology (01.01.1997)
Get full text
Journal Article