A general approach for haplotype phasing across the full spectrum of relatedness
O'Connell, Jared, Gurdasani, Deepti, Delaneau, Olivier, Pirastu, Nicola, Ulivi, Sheila, Cocca, Massimiliano, Traglia, Michela, Huang, Jie, Huffman, Jennifer E, Rudan, Igor, McQuillan, Ruth, Fraser, Ross M, Campbell, Harry, Polasek, Ozren, Asiki, Gershim, Ekoru, Kenneth, Hayward, Caroline, Wright, Alan F, Vitart, Veronique, Navarro, Pau, Zagury, Jean-Francois, Wilson, James F, Toniolo, Daniela, Gasparini, Paolo, Soranzo, Nicole, Sandhu, Manjinder S, Marchini, Jonathan
Published in PLoS genetics (01.04.2014)
Published in PLoS genetics (01.04.2014)
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Novel insights into the genetics of smoking behaviour, lung function, and chronic obstructive pulmonary disease (UK BiLEVE): a genetic association study in UK Biobank
Wain, Louise V, Shrine, Nick, Miller, Suzanne, Jackson, Victoria E, Ntalla, Ioanna, Soler Artigas, María, Billington, Charlotte K, Kheirallah, Abdul Kader, Allen, Richard, Cook, James P, Probert, Kelly, Obeidat, Ma'en, Bossé, Yohan, Hao, Ke, Postma, Dirkje S, Paré, Peter D, Ramasamy, Adaikalavan, Mägi, Reedik, Mihailov, Evelin, Reinmaa, Eva, Melén, Erik, O'Connell, Jared, Frangou, Eleni, Delaneau, Olivier, Freeman, Colin, Petkova, Desislava, McCarthy, Mark, Sayers, Ian, Deloukas, Panos, Hubbard, Richard, Pavord, Ian, Hansell, Anna L, Thomson, Neil C, Zeggini, Eleftheria, Morris, Andrew P, Marchini, Jonathan, Strachan, David P, Tobin, Martin D, Hall, Ian P
Published in The lancet respiratory medicine (01.10.2015)
Published in The lancet respiratory medicine (01.10.2015)
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Journal Article
Influence of autozygosity on common disease risk across the phenotypic spectrum
Malawsky, Daniel S., van Walree, Eva, Jacobs, Benjamin M., Heng, Teng Hiang, Huang, Qin Qin, Sabir, Ataf H., Rahman, Saadia, Sharif, Saghira Malik, Khan, Ahsan, Mirkov, Maša Umićević, Kuwahara, Hiroyuki, Gao, Xin, Alkuraya, Fowzan S., Posthuma, Danielle, Newman, William G., Griffiths, Christopher J., Mathur, Rohini, van Heel, David A., Finer, Sarah, O’Connell, Jared, Martin, Hilary C.
Published in Cell (12.10.2023)
Published in Cell (12.10.2023)
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Journal Article
Prevalence of Alpha-1 Antitrypsin Deficiency, Self-Reported Behavior Change, and Health Care Engagement Among Direct-to-Consumer Recipients of a Personalized Genetic Risk Report
Ashenhurst, James R., Nhan, Hoang, Shelton, Janie F., Wu, Shirley, Tung, Joyce Y., Elson, Sarah L., Stoller, James K., Agee, Michelle, Aslibekyan, Stella, Auton, Adam, Babalola, Elizabeth, Bell, Robert K., Bielenberg, Jessica, Bryc, Katarzyna, Bullis, Emily, Cameron, Briana, Coker, Daniella, Partida, Gabriel Cuellar, Dhamija, Devika, Das, Sayantan, Elson, Sarah L., Filshtein, Teresa, Fletez-Brant, Kipper, Fontanillas, Pierre, Freyman, Will, Gandhi, Pooja M., Heilbron, Karl, Hicks, Barry, Hinds, David A., Huber, Karen E., Jewett, Ethan M., Jiang, Yunxuan, Kleinman, Aaron, Kukar, Katelyn, Lane, Vanessa A., Lin, Keng-Han, Lowe, Maya, Luff, Marie K., McCreight, Jennifer C., McIntyre, Matthew H., McManus, Kimberly F., Micheletti, Steven J., Moreno, Meghan E., Mountain, Joanna L., Mozaffari, Sahar V., Nandakumar, Priyanka, Noblin, Elizabeth S., O’Connell, Jared, Petrakovitz, Aaron A., Poznik, G. David, Schumacher, Morgan, Shastri, Anjali J., Shelton, Janie F., Shi, Jingchunzi, Shringarpure, Suyash, Tian, Chao, Tran, Vinh, Tung, Joyce Y., Wang, Xin, Wang, Wei, Weldon, Catherine H., Wilton, Peter
Published in Chest (01.02.2022)
Published in Chest (01.02.2022)
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Journal Article
Multicohort analysis of the maternal age effect on recombination
Martin, Hilary C., Christ, Ryan, Hussin, Julie G., O’Connell, Jared, Gordon, Scott, Mbarek, Hamdi, Hottenga, Jouke-Jan, McAloney, Kerrie, Willemsen, Gonnecke, Gasparini, Paolo, Pirastu, Nicola, Montgomery, Grant W., Navarro, Pau, Soranzo, Nicole, Toniolo, Daniela, Vitart, Veronique, Wilson, James F., Marchini, Jonathan, Boomsma, Dorret I., Martin, Nicholas G., Donnelly, Peter
Published in Nature communications (05.08.2015)
Published in Nature communications (05.08.2015)
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Journal Article
Tracking human population structure through time from whole genome sequences
Wang, Ke, Mathieson, Iain, O'Connell, Jared, Schiffels, Stephan
Published in PLoS genetics (09.03.2020)
Published in PLoS genetics (09.03.2020)
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Journal Article
MUSSEL: Enhanced Bayesian polygenic risk prediction leveraging information across multiple ancestry groups
Jin, Jin, Zhan, Jianan, Zhang, Jingning, Zhao, Ruzhang, O’Connell, Jared, Jiang, Yunxuan, Aslibekyan, Stella, Auton, Adam, Babalola, Elizabeth, Bell, Robert K., Bielenberg, Jessica, Bryc, Katarzyna, Bullis, Emily, Coker, Daniella, Cuellar Partida, Gabriel, Dhamija, Devika, Das, Sayantan, Elson, Sarah L., Eriksson, Nicholas, Filshtein, Teresa, Fitch, Alison, Fletez-Brant, Kipper, Fontanillas, Pierre, Freyman, Will, Granka, Julie M., Heilbron, Karl, Hernandez, Alejandro, Hicks, Barry, Hinds, David A., Jewett, Ethan M., Jiang, Yunxuan, Kukar, Katelyn, Kwong, Alan, Lin, Keng-Han, Llamas, Bianca A., Lowe, Maya, McCreight, Jey C., McIntyre, Matthew H., Micheletti, Steven J., Moreno, Meghan E., Nandakumar, Priyanka, Nguyen, Dominique T., Noblin, Elizabeth S., O’Connell, Jared, Petrakovitz, Aaron A., Poznik, G. David, Reynoso, Alexandra, Schumacher, Morgan, Shastri, Anjali J., Shelton, Janie F., Shi, Jingchunzi, Shringarpure, Suyash, Su, Qiaojuan Jane, Tat, Susana A., Tchakouté, Christophe Toukam, Tran, Vinh, Tung, Joyce Y., Wang, Xin, Wang, Wei, Weldon, Catherine H., Wilton, Peter, Wong, Corinna D., Buyske, Steven, Gignoux, Christopher, Haiman, Christopher, Kenny, Eimear E., Kooperberg, Charles, North, Kari, Koelsch, Bertram L., Wojcik, Genevieve, Zhang, Haoyu, Chatterjee, Nilanjan
Published in Cell genomics (10.04.2024)
Published in Cell genomics (10.04.2024)
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Journal Article
The UK Biobank resource with deep phenotyping and genomic data
Bycroft, Clare, Freeman, Colin, Petkova, Desislava, Band, Gavin, Elliott, Lloyd T., Sharp, Kevin, Motyer, Allan, Vukcevic, Damjan, Delaneau, Olivier, O’Connell, Jared, Cortes, Adrian, Welsh, Samantha, Young, Alan, Effingham, Mark, McVean, Gil, Leslie, Stephen, Allen, Naomi, Donnelly, Peter, Marchini, Jonathan
Published in Nature (London) (01.10.2018)
Published in Nature (London) (01.10.2018)
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Journal Article
NxTrim: optimized trimming of Illumina mate pair reads
O'Connell, Jared, Schulz-Trieglaff, Ole, Carlson, Emma, Hims, Matthew M, Gormley, Niall A, Cox, Anthony J
Published in Bioinformatics (Oxford, England) (15.06.2015)
Published in Bioinformatics (Oxford, England) (15.06.2015)
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Journal Article
An ensemble penalized regression method for multi-ancestry polygenic risk prediction
Zhang, Jingning, Zhan, Jianan, Jin, Jin, Ma, Cheng, Zhao, Ruzhang, O’Connell, Jared, Jiang, Yunxuan, Koelsch, Bertram L., Zhang, Haoyu, Chatterjee, Nilanjan
Published in Nature communications (15.04.2024)
Published in Nature communications (15.04.2024)
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Journal Article
AKT: ancestry and kinship toolkit
Arthur, Rudy, Schulz-Trieglaff, Ole, Cox, Anthony J, O'Connell, Jared
Published in Bioinformatics (Oxford, England) (01.01.2017)
Published in Bioinformatics (Oxford, England) (01.01.2017)
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Journal Article
Nuclear genome-wide associations with mitochondrial heteroplasmy
Nandakumar, Priyanka, Tian, Chao, O'Connell, Jared, Hinds, David, Paterson, Andrew D, Sondheimer, Neal
Published in Science advances (01.03.2021)
Published in Science advances (01.03.2021)
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Journal Article
Haplotype estimation for biobank-scale data sets
O'Connell, Jared, Sharp, Kevin, Shrine, Nick, Wain, Louise, Hall, Ian, Tobin, Martin, Zagury, Jean-Francois, Delaneau, Olivier, Marchini, Jonathan
Published in Nature genetics (01.07.2016)
Published in Nature genetics (01.07.2016)
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Journal Article
NxRepair: error correction in de novo sequence assembly using Nextera mate pairs
Murphy, Rebecca R, O'Connell, Jared, Cox, Anthony J, Schulz-Trieglaff, Ole
Published in PeerJ (San Francisco, CA) (02.06.2015)
Published in PeerJ (San Francisco, CA) (02.06.2015)
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Journal Article
Multitrait genetic association analysis identifies 50 new risk loci for gastro-oesophageal reflux, seven new loci for Barrett’s oesophagus and provides insights into clinical heterogeneity in reflux diagnosis
Ong, Jue-Sheng, An, Jiyuan, Han, Xikun, Law, Matthew H, Nandakumar, Priyanka, Schumacher, Johannes, Gockel, Ines, Bohmer, Anne, Jankowski, Janusz, Palles, Claire, Olsen, Catherine M, Neale, Rachel E, Fitzgerald, Rebecca, Thrift, Aaron P, Vaughan, Thomas L, Buas, Matthew F, Hinds, David A, Gharahkhani, Puya, Kendall, Bradley J, MacGregor, Stuart, Fitzgerald, Rebecca, Buas, Matt, Gammon, Marilie D, Corley, Douglas A, Shaheen, Nicholas J, Hardie, Laura J, Bird, Nigel C, Reid, Brian J, Chow, Wong-Ho, Risch, Harvey A, Ye, Weimin, Liu, Geoffrey, Romero, Yvonne, Bernstein, Leslie, Wu, Anna H, Schumacher, Johannes, Gockel, Ines, Bohmer, Anne, Jankowski, Janusz, Palles, Claire, Whiteman, David C, Agee, Michelle, Aslibekyan, Stella, Auton, Adam, Bell, Robert K, Bryc, Katarzyna, Clark, Sarah K, Elson, Sarah L, Fletez-Brant, Kipper, Fontanillas, Pierre, Furlotte, Nicholas A, Gandhi, Pooja M, Heilbron, Karl, Hicks, Barry, Hinds, David A, Huber, Karen E, Jewett, Ethan M, Jiang, Yunxuan, Kleinman, Aaron, Lin, Keng-Han, Litterman, Nadia K, Luff, Marie K, McCreight, Jennifer C, McIntyre, Matthew H, McManus, Kimberly F, Mountain, Joanna L, Mozaffari, Sahar V, Nandakumar, Priyanka, Noblin, Elizabeth S, Northover, Carrie AM, O'Connell, Jared, Petrakovitz, Aaron A, Pitts, Steven J, David Poznik, G., Fah Sathirapongsasuti, J, Shastri, Anjali J, Shelton, Janie F, Shringarpure, Suyash, Tian, Chao, Tung, Joyce Y, Tunney, Robert J, Vacic, Vladimir, Wang, Xin, Zare, Amir S
Published in Gut (01.06.2022)
Published in Gut (01.06.2022)
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Journal Article
A population-specific reference panel for improved genotype imputation in African Americans
O’Connell, Jared, Yun, Taedong, Moreno, Meghan, Li, Helen, Litterman, Nadia, Kolesnikov, Alexey, Noblin, Elizabeth, Chang, Pi-Chuan, Shastri, Anjali, Dorfman, Elizabeth H., Shringarpure, Suyash, Auton, Adam, Carroll, Andrew, McLean, Cory Y.
Published in Communications biology (05.11.2021)
Published in Communications biology (05.11.2021)
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Journal Article
A new method for multiancestry polygenic prediction improves performance across diverse populations
Zhang, Haoyu, Zhan, Jianan, Jin, Jin, Zhang, Jingning, Lu, Wenxuan, Zhao, Ruzhang, Ahearn, Thomas U., Yu, Zhi, O’Connell, Jared, Jiang, Yunxuan, Chen, Tony, Okuhara, Dayne, Garcia-Closas, Montserrat, Lin, Xihong, Koelsch, Bertram L., Chatterjee, Nilanjan
Published in Nature genetics (01.10.2023)
Published in Nature genetics (01.10.2023)
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