Effect of Combined Immune Checkpoint Inhibition vs Best Supportive Care Alone in Patients With Advanced Colorectal Cancer: The Canadian Cancer Trials Group CO.26 Study
Chen, Eric X, Jonker, Derek J, Loree, Jonathan M, Kennecke, Hagen F, Berry, Scott R, Couture, Felix, Ahmad, Chaudhary E, Goffin, John R, Kavan, Petr, Harb, Mohammed, Colwell, Bruce, Samimi, Setareh, Samson, Benoit, Abbas, Tahir, Aucoin, Nathalie, Aubin, Francine, Koski, Sheryl L, Wei, Alice C, Magoski, Nadine M, Tu, Dongsheng, O'Callaghan, Chris J
Published in JAMA oncology (01.06.2020)
Published in JAMA oncology (01.06.2020)
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Association of KRAS p.G13D Mutation With Outcome in Patients With Chemotherapy-Refractory Metastatic Colorectal Cancer Treated With Cetuximab
De Roock, Wendy, Jonker, Derek J, Di Nicolantonio, Federica, Sartore-Bianchi, Andrea, Tu, Dongsheng, Siena, Salvatore, Lamba, Simona, Arena, Sabrina, Frattini, Milo, Piessevaux, Hubert, Van Cutsem, Eric, O’Callaghan, Chris J, Khambata-Ford, Shirin, Zalcberg, John R, Simes, John, Karapetis, Christos S, Bardelli, Alberto, Tejpar, Sabine
Published in JAMA : the journal of the American Medical Association (27.10.2010)
Published in JAMA : the journal of the American Medical Association (27.10.2010)
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Cetuximab for the Treatment of Colorectal Cancer
Jonker, Derek J, O'Callaghan, Chris J, Karapetis, Christos S, Zalcberg, John R, Tu, Dongsheng, Au, Heather-Jane, Berry, Scott R, Krahn, Marianne, Price, Timothy, Simes, R. John, Tebbutt, Niall C, van Hazel, Guy, Wierzbicki, Rafal, Langer, Christiane, Moore, Malcolm J
Published in The New England journal of medicine (15.11.2007)
Published in The New England journal of medicine (15.11.2007)
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Plasma versus tissue tumor mutational burden as biomarkers of durvalumab plus tremelimumab response in patients with metastatic colorectal cancer in the CO.26 trial
Loree, Jonathan M, Titmuss, Emma, Topham, James T, Kennecke, Hagen F, Feilotter, Harriet, Virk, Shakeel, Lee, Young S, Banks, Kimberly, Quinn, Katie, Karsan, Aly, Renouf, Daniel J, Jonker, Derek J, Tu, Dongsheng, O'Callaghan, Chris J, Chen, Eric X
Published in Clinical cancer research (01.08.2024)
Published in Clinical cancer research (01.08.2024)
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Transverse Colon Primary Tumor Location as a Biomarker in Metastatic Colorectal Cancer: A Pooled Analysis of CCTG/AGITG CO.17 and CO.20 Randomized Clinical Trials
Solar Vasconcelos, Joao Paulo, Chen, Nan, Titmuss, Emma, Tu, Dongsheng, Brule, Stephanie Y, Goodwin, Rachel, Jonker, Derek J, Price, Timothy, Zalcberg, John R, Moore, Malcolm J, Karapetis, Christos S, Siu, Lillian, Shapiro, Jeremy, Simes, John, Gill, Sharlene, O'Callaghan, Chris J, Loree, Jonathan M
Published in Clinical cancer research (15.03.2024)
Published in Clinical cancer research (15.03.2024)
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Expanded Low Allele Frequency RAS and BRAF V600E Testing in Metastatic Colorectal Cancer as Predictive Biomarkers for Cetuximab in the Randomized CO.17 Trial
Loree, Jonathan M, Dowers, Anthony, Tu, Dongsheng, Jonker, Derek J, Edelstein, Daniel L, Quinn, Hannah, Holtrup, Frank, Price, Timothy, Zalcberg, John R, Moore, Malcolm J, Karapetis, Christos S, O'Callaghan, Chris J, Waring, Paul, Kennecke, Hagen F, Hamilton, Stanley R, Kopetz, Scott
Published in Clinical cancer research (01.01.2021)
Published in Clinical cancer research (01.01.2021)
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Marizomib for patients with newly diagnosed glioblastoma: A randomized phase 3 trial
Roth, Patrick, Gorlia, Thierry, Reijneveld, Jaap C, de Vos, Filip, Idbaih, Ahmed, Frenel, Jean-Sébastien, Le Rhun, Emilie, Sepulveda, Juan Manuel, Perry, James, Masucci, G Laura, Freres, Pierre, Hirte, Hal, Seidel, Clemens, Walenkamp, Annemiek, Lukacova, Slavka, Meijnders, Paul, Blais, Andre, Ducray, Francois, Verschaeve, Vincent, Nicholas, Garth, Balana, Carmen, Bota, Daniela A, Preusser, Matthias, Nuyens, Sarah, Dhermain, Fréderic, van den Bent, Martin, O’Callaghan, Chris J, Vanlancker, Maureen, Mason, Warren, Weller, Michael
Published in Neuro-oncology (Charlottesville, Va.) (05.09.2024)
Published in Neuro-oncology (Charlottesville, Va.) (05.09.2024)
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Phase III Randomized, Placebo-Controlled Study of Cetuximab Plus Brivanib Alaninate Versus Cetuximab Plus Placebo in Patients With Metastatic, Chemotherapy-Refractory, Wild-Type K-RAS Colorectal Carcinoma: The NCIC Clinical Trials Group and AGITG CO.20 Trial
SIU, Lillian L, SHAPIRO, Jeremy D, NOTT, Louise M, CHARPENTIER, Danielle, LIAUW, Winston, SAWYER, Michael B, JEFFORD, Michael, MAGOSKI, Nadine M, HAYDON, Andrew, WALTERS, Ian, RINGASH, Jolie, DONGSHENG TU, JONKER, Derek J, O'CALLAGHAN, Chris J, KARAPETIS, Chris S, ZALCBERG, John R, SIMES, John, COUTURE, Felix, MOORE, Malcolm J, PRICE, Timothy J, SIDDIQUI, Jehan
Published in Journal of clinical oncology (01.07.2013)
Published in Journal of clinical oncology (01.07.2013)
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Optimizing the number of variants tracked to follow disease burden with circulating tumor DNA assays in metastatic colorectal cancer
Boutin, Mélina, Topham, James T., Feilotter, Harriet, Kennecke, Hagen F., Couture, Félix, Harb, Mohammed, Kavan, Peter, Berry, Scott, Lim, Howard J., Goffin, John R., Ahmad, Chaudhary, Lott, Anthony, Renouf, Daniel J., Jonker, Derek J., Tu, Dongsheng, O’Callaghan, Chris J., Chen, Eric X., Loree, Jonathan M.
Published in Therapeutic advances in medical oncology (01.01.2023)
Published in Therapeutic advances in medical oncology (01.01.2023)
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Liver Metastases and Immune Checkpoint Inhibitor Efficacy in Patients With Refractory Metastatic Colorectal Cancer: A Secondary Analysis of a Randomized Clinical Trial
Chen, Eric X, Loree, Jonathan M, Titmuss, Emma, Jonker, Derek J, Kennecke, Hagen F, Berry, Scott, Couture, Felix, Ahmad, Chaudharry E, Goffin, John R, Kavan, Petr, Harb, Mohammed, Colwell, Bruce, Samimi, Setareh, Samson, Benoit, Abbas, Tahir, Aucoin, Nathalie, Aubin, Francine, Koski, Sheryl, Wei, Alice C, Tu, Dongsheng, O'Callaghan, Chris J
Published in JAMA network open (01.12.2023)
Published in JAMA network open (01.12.2023)
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Clustering on longitudinal quality‐of‐life measurements using growth mixture models for clinical prognosis: Implementation on CCTG/AGITG CO.20 trial
Zhang, Jiahui, Kong, Weili, Hu, Pingzhao, Jonker, Derek, Moore, Malcolm, Ringash, Jolie, Shapiro, Jeremy, Zalcberg, John, Simes, John, Tu, Dongsheng, O'Callaghan, Chris J., Liu, Geoffrey, Xu, Wei
Published in Cancer medicine (Malden, MA) (01.03.2023)
Published in Cancer medicine (Malden, MA) (01.03.2023)
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Clinical and metabolomic characterization of Brivanib‐Induced hypertension in metastatic colorectal cancer
Rattner, Jodi I., Kopciuk, Karen A., Vogel, Hans J., Tang, Patricia A., Shapiro, Jeremy D., Tu, Dongsheng, Jonker, Derek J., Siu, Lillian L., O'Callaghan, Chris J., Bathe, Oliver F.
Published in Cancer medicine (Malden, MA) (01.08.2023)
Published in Cancer medicine (Malden, MA) (01.08.2023)
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Health-Related Quality of Life in Patients With Advanced Colorectal Cancer Treated With Cetuximab: Overall and KRAS-Specific Results of the NCIC CTG and AGITG CO.17 Trial
Au, Heather-Jane, Karapetis, Christos S., O'Callaghan, Chris J., Tu, Dongsheng, Moore, Malcolm J., Zalcberg, John R., Kennecke, Hagen, Shapiro, Jeremy D., Koski, Sheryl, Pavlakis, Nick, Charpentier, Danielle, Wyld, David, Jefford, Michael, Knight, Gregory J., Magoski, Nadine M., Brundage, Michael D., Jonker, Derek J.
Published in Journal of clinical oncology (10.04.2009)
Published in Journal of clinical oncology (10.04.2009)
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Impact of lymphopenia on survival for elderly patients with glioblastoma: A secondary analysis of the CCTG CE.6 (EORTC 26062-22061, TROG03.01) randomized clinical trial
Song, Andrew J, Ding, Keyue, Alnahhas, Iyad, Laperriere, Normand J, Perry, James, Mason, Warren P, Winch, Chad, O'Callaghan, Chris J, Menten, Johan J, Brandes, Alba A, Phillips, Claire, Fay, Michael F, Nishikawa, Ryo, Osoba, David, Cairncross, J Gregory, Roa, Wilson, Wick, Wolfgang, Shi, Wenyin
Published in Neuro-oncology advances (01.01.2021)
Published in Neuro-oncology advances (01.01.2021)
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Outcomes of Older Patients (≥ 70 Years) Treated With Targeted Therapy in Metastatic Chemorefractory Colorectal Cancer: Retrospective Analysis of NCIC CTG CO.17 and CO.20
Wells, J. Connor, Tu, Dongsheng, Siu, Lillian L., Shapiro, Jeremy D., Jonker, Derek J., Karapetis, Christos, Simes, John, Liu, Geoffrey, Price, Timothy J., Tebbutt, Niall C., O’Callaghan, Chris J.
Published in Clinical colorectal cancer (01.03.2019)
Published in Clinical colorectal cancer (01.03.2019)
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The relationship between rash, tumour KRAS mutation status and clinical and quality of life outcomes in patients with advanced colorectal cancer treated with cetuximab in the NCIC CTG/AGITG CO.17
Sommeijer, Dirkje W., Karapetis, Christos S., Zalcberg, John R., Tu, Dongsheng, Jonker, Derek J., Simes, John, Tebbutt, Niall, Yip, Desmond, Price, Timothy J., O'Callaghan, Chris J.
Published in Acta oncologica (01.07.2014)
Published in Acta oncologica (01.07.2014)
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The CCTG PA.7 phase II trial of gemcitabine and nab-paclitaxel with or without durvalumab and tremelimumab as initial therapy in metastatic pancreatic ductal adenocarcinoma
Renouf, Daniel J, Loree, Jonathan M, Knox, Jennifer J, Topham, James T, Kavan, Petr, Jonker, Derek, Welch, Stephen, Couture, Felix, Lemay, Frederic, Tehfe, Mustapha, Harb, Mohammed, Aucoin, Nathalie, Ko, Yoo-Joung, Tang, Patricia A, Ramjeesingh, Ravi, Meyers, Brandon M, Kim, Christina A, Du, Pan, Jia, Shidong, Schaeffer, David F, Gill, Sharlene, Tu, Dongsheng, O'Callaghan, Chris J
Published in Nature communications (26.08.2022)
Published in Nature communications (26.08.2022)
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Circulating Tumor DNA Identifies Diverse Landscape of Acquired Resistance to Anti-Epidermal Growth Factor Receptor Therapy in Metastatic Colorectal Cancer
Topham, James T, O'Callaghan, Chris J, Feilotter, Harriet, Kennecke, Hagen F, Lee, Young S, Li, Weimin, Banks, Kimberly C, Quinn, Katie, Renouf, Daniel J, Jonker, Derek J, Tu, Dongsheng, Chen, Eric X, Loree, Jonathan M
Published in Journal of clinical oncology (20.01.2023)
Published in Journal of clinical oncology (20.01.2023)
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Journal Article
K-ras Mutations and Benefit from Cetuximab in Advanced Colorectal Cancer
Karapetis, Christos S, Khambata-Ford, Shirin, Jonker, Derek J, O'Callaghan, Chris J, Tu, Dongsheng, Tebbutt, Niall C, Simes, R. John, Chalchal, Haji, Shapiro, Jeremy D, Robitaille, Sonia, Price, Timothy J, Shepherd, Lois, Au, Heather-Jane, Langer, Christiane, Moore, Malcolm J, Zalcberg, John R
Published in The New England journal of medicine (23.10.2008)
Published in The New England journal of medicine (23.10.2008)
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