Chronic Glucocorticoid Exposure Induced an S1PR2-RORγ Axis to Enhance Hepatic Gluconeogenesis in Male Mice
Lee, Rebecca A, Chang, Maggie, Tsay, Ariel, Lee, Yeong Rim, Li, Danielle, Yiv, Nicholas, Tian, Sharon, Zhao, Michelle, O'Brien, Richard M, Wang, Jen-Chywan
Published in Diabetes (New York, N.Y.) (01.11.2023)
Published in Diabetes (New York, N.Y.) (01.11.2023)
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G6PC1 and G6PC2 influence G6P flux but not HSD11B1 activity
Hawes, Emily M, Boortz, Kayla A, Oeser, James K, O'Rourke, Margaret L, O'Brien, Richard M
Published in Journal of molecular endocrinology (01.11.2023)
Published in Journal of molecular endocrinology (01.11.2023)
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Deletion of the mouse Slc30a8 gene encoding zinc transporter-8 results in impaired insulin secretion
Pound, Lynley D, Sarkar, Suparna A, Benninger, Richard K P, Wang, Yingda, Suwanichkul, Adisak, Shadoan, Melanie K, Printz, Richard L, Oeser, James K, Lee, Catherine E, Piston, David W, McGuinness, Owen P, Hutton, John C, Powell, David R, O'Brien, Richard M
Published in Biochemical journal (15.07.2009)
Published in Biochemical journal (15.07.2009)
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Nonsynonymous single-nucleotide polymorphisms in the G6PC2 gene affect protein expression, enzyme activity, and fasting blood glucose
Overway, Emily M., Bosma, Karin J., Claxton, Derek P., Oeser, James K., Singh, Kritika, Breidenbach, Lindsay B., Mchaourab, Hassane S., Davis, Lea K., O'Brien, Richard M.
Published in The Journal of biological chemistry (01.02.2022)
Published in The Journal of biological chemistry (01.02.2022)
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An Enhancer Within Abcb11 Regulates G6pc2 in C57BL/6 Mouse Pancreatic Islets
Keller, Mark P, Hawes, Emily M, Schueler, Kathryn L, Stapleton, Donnie S, Mitok, Kelly A, Simonett, Shane P, Oeser, James K, Sampson, Leesa L, Attie, Alan D, Magnuson, Mark A, O'Brien, Richard M
Published in Diabetes (New York, N.Y.) (01.11.2023)
Published in Diabetes (New York, N.Y.) (01.11.2023)
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The Diabetes Susceptibility Gene SLC30A8 that Encodes the Zinc Transporter ZnT8 is a Pseudogene in Guinea Pigs Potentially Contributing to Low Guinea Pig Islet Zinc Content
Syring, Kristen E., Bosma, Karin J., Oeser, James K., Shiota, Masakazu, O’Brien, Richard M.
Published in Journal of molecular evolution (01.12.2018)
Published in Journal of molecular evolution (01.12.2018)
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Crystal structures reveal a new and novel FoxO1 binding site within the human glucose-6-phosphatase catalytic subunit 1 gene promoter
Singh, Puja, Han, Eun Hee, Endrizzi, James A., O'Brien, Richard M., Chi, Young-In
Published in Journal of structural biology (01.04.2017)
Published in Journal of structural biology (01.04.2017)
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Functional Analysis of Mouse G6pc1 Mutations Using a Novel In Situ Assay for Glucose-6-Phosphatase Activity and the Effect of Mutations in Conserved Human G6PC1/G6PC2 Amino Acids on G6PC2 Protein Expression
Boortz, Kayla A, Syring, Kristen E, Pound, Lynley D, Wang, Yingda, Oeser, James K, O'Brien, Richard M
Published in PloS one (09.09.2016)
Published in PloS one (09.09.2016)
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Combined Deletion of Slc30a7 and Slc30a8 Unmasks a Critical Role for ZnT8 in Glucose-Stimulated Insulin Secretion
Syring, Kristen E, Boortz, Kayla A, Oeser, James K, Ustione, Alessandro, Platt, Kenneth A, Shadoan, Melanie K, McGuinness, Owen P, Piston, David W, Powell, David R, O'Brien, Richard M
Published in Endocrinology (Philadelphia) (01.12.2016)
Published in Endocrinology (Philadelphia) (01.12.2016)
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Evidence that Evolution of the Diabetes Susceptibility Gene SLC30A8 that Encodes the Zinc Transporter ZnT8 Drives Variations in Pancreatic Islet Zinc Content in Multiple Species
Bosma, Karin J., Syring, Kristen E., Oeser, James K., Lee, Jason D., Benninger, Richard K. P., Pamenter, Matthew E., O’Brien, Richard M.
Published in Journal of molecular evolution (01.07.2019)
Published in Journal of molecular evolution (01.07.2019)
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Insulin's direct hepatic effect explains the inhibition of glucose production caused by insulin secretion
Edgerton, Dale S, Kraft, Guillaume, Smith, Marta, Farmer, Ben, Williams, Phillip E, Coate, Katie C, Printz, Richard L, O'Brien, Richard M, Cherrington, Alan D
Published in JCI insight (23.03.2017)
Published in JCI insight (23.03.2017)
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G6PC2 Modulates the Effects of Dexamethasone on Fasting Blood Glucose and Glucose Tolerance
Boortz, Kayla A, Syring, Kristen E, Lee, Rebecca A, Dai, Chunhua, Oeser, James K, McGuinness, Owen P, Wang, Jen-Chywan, O'Brien, Richard M
Published in Endocrinology (Philadelphia) (01.11.2016)
Published in Endocrinology (Philadelphia) (01.11.2016)
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Zinc transporter 8 haploinsufficiency protects against beta cell dysfunction in type 1 diabetes by increasing mitochondrial respiration
Kim, Yong Kyung, Walters, Jay A., Moss, Nicole D., Wells, Kristen L., Sheridan, Ryan, Miranda, Jose G., Benninger, Richard K.P., Pyle, Laura L., O'Brien, Richard M., Sussel, Lori, Davidson, Howard W.
Published in Molecular metabolism (Germany) (01.12.2022)
Published in Molecular metabolism (Germany) (01.12.2022)
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The pancreatic islet β-cell-enriched transcription factor Pdx-1 regulates Slc30a8 gene transcription through an intronic enhancer
Pound, Lynley D, Hang, Yan, Sarkar, Suparna A, Wang, Yingda, Milam, Laurel A, Oeser, James K, Printz, Richard L, Lee, Catherine E, Stein, Roland, Hutton, John C, O'Brien, Richard M
Published in Biochemical journal (01.01.2011)
Published in Biochemical journal (01.01.2011)
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