Bottlenecks and selective sweeps during domestication have increased deleterious genetic variation in dogs
Marsden, Clare D., Vecchyo, Diego Ortega-Del, O’Brien, Dennis P., Taylor, Jeremy F., Ramirez, Oscar, Vilà, Carles, Marques-Bonet, Tomas, Schnabel, Robert D., Wayne, Robert K., Lohmueller, Kirk E.
Published in Proceedings of the National Academy of Sciences - PNAS (05.01.2016)
Published in Proceedings of the National Academy of Sciences - PNAS (05.01.2016)
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Journal Article
International veterinary canine dyskinesia task force ECVN consensus statement: Terminology and classification
Cerda‐Gonzalez, Sofia, Packer, Rebecca A., Garosi, Laurent, Lowrie, Mark, Mandigers, Paul J. J., O'Brien, Dennis P., Volk, Holger A.
Published in Journal of veterinary internal medicine (01.05.2021)
Published in Journal of veterinary internal medicine (01.05.2021)
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Journal Article
Neuronal Ceroid Lipofuscinosis in a Domestic Cat Associated with a DNA Sequence Variant That Creates a Premature Stop Codon in CLN6
Katz, Martin L, Buckley, Reuben M, Biegen, Vanessa, O'Brien, Dennis P, Johnson, Gayle C, Warren, Wesley C, Lyons, Leslie A
Published in G3 : genes - genomes - genetics (01.08.2020)
Published in G3 : genes - genomes - genetics (01.08.2020)
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Journal Article
A mixed breed dog with neuronal ceroid lipofuscinosis is homozygous for a CLN5 nonsense mutation previously identified in Border Collies and Australian Cattle Dogs
Villani, Natalie A., Bullock, Garrett, Michaels, Jennifer R., Yamato, Osamu, O'Brien, Dennis P., Mhlanga-Mutangadura, Tendai, Johnson, Gary S., Katz, Martin L.
Published in Molecular genetics and metabolism (01.05.2019)
Published in Molecular genetics and metabolism (01.05.2019)
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Journal Article
Novel Homozygous ADAMTS2 Variants and Associated Disease Phenotypes in Dogs with Dermatosparactic Ehlers-Danlos Syndrome
Jaffey, Jared A, Bullock, Garrett, Guo, Juyuan, Mhlanga-Mutangadura, Tendai, O'Brien, Dennis P, Coates, Joan R, Morrissey, Rochelle, Hutchison, Robert, Donnelly, Kevin S, Cohn, Leah A, Katz, Martin L, Johnson, Gary S
Published in Genes (19.11.2022)
Published in Genes (19.11.2022)
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Journal Article
Smart grid coordination of a chemical processing plant
Feng, Jianyuan, Brown, Avery, O’Brien, Dennis, Chmielewski, Donald J.
Published in Chemical engineering science (02.11.2015)
Published in Chemical engineering science (02.11.2015)
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A Feasibility Pilot Study of Online Modules of Hydroxyurea and Sickle Cell Disease Care for Adolescents and Young Adults for Family Medicine Residents
Dawson, Amy, Mullen, Kelly, Janson, Isaac A, Henriksen, Brian, Duncan, Natalie, O'Brien, Dennis, Meier, Emily R
Published in Journal of pediatric hematology/oncology (01.03.2022)
Published in Journal of pediatric hematology/oncology (01.03.2022)
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Journal Article
An Inversion Disrupting FAM134B Is Associated with Sensory Neuropathy in the Border Collie Dog Breed
Forman, Oliver P, Hitti, Rebekkah J, Pettitt, Louise, Jenkins, Christopher A, O'Brien, Dennis P, Shelton, G Diane, De Risio, Luisa, Quintana, Rodrigo Gutierrez, Beltran, Elsa, Mellersh, Cathryn
Published in G3 : genes - genomes - genetics (01.09.2016)
Published in G3 : genes - genomes - genetics (01.09.2016)
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Journal Article
A homozygous PIGN missense mutation in Soft-Coated Wheaten Terriers with a canine paroxysmal dyskinesia
Kolicheski, Ana L., Johnson, Gary S., Mhlanga-Mutangadura, Tendai, Taylor, Jeremy F., Schnabel, Robert D., Kinoshita, Taroh, Murakami, Yoshiko, O’Brien, Dennis P.
Published in Neurogenetics (01.01.2017)
Published in Neurogenetics (01.01.2017)
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Journal Article
A truncating mutation in ATP13A2 is responsible for adult-onset neuronal ceroid lipofuscinosis in Tibetan terriers
Farias, Fabiana H.G, Zeng, Rong, Johnson, Gary S, Wininger, Fred A, Taylor, Jeremy F, Schnabel, Robert D, McKay, Stephanie D, Sanders, Douglas N, Lohi, Hannes, Seppälä, Eija H, Wade, Claire M, Lindblad-Toh, Kerstin, O'Brien, Dennis P, Katz, Martin L
Published in Neurobiology of disease (01.06.2011)
Published in Neurobiology of disease (01.06.2011)
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Journal Article
Dermatologic adverse events associated with afatinib: an oral ErbB family blocker
Lacouture, Mario E, Schadendorf, Dirk, Chu, Chia-Yu, Uttenreuther-Fischer, Martina, Stammberger, Uz, O'Brien, Dennis, Hauschild, Axel
Published in Expert review of anticancer therapy (01.06.2013)
Published in Expert review of anticancer therapy (01.06.2013)
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Journal Article
A mutation in canine PPT1 causes early onset neuronal ceroid lipofuscinosis in a Dachshund
Sanders, Douglas N., Farias, Fabiana H., Johnson, Gary S., Chiang, Vivian, Cook, James R., O’Brien, Dennis P., Hofmann, Sandra L., Lu, Jui-Yun, Katz, Martin L.
Published in Molecular genetics and metabolism (01.08.2010)
Published in Molecular genetics and metabolism (01.08.2010)
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Journal Article
A novel mutation in CLCN1 associated with feline myotonia congenita
Gandolfi, Barbara, Daniel, Rob J, O'Brien, Dennis P, Guo, Ling T, Youngs, Melanie D, Leach, Stacey B, Jones, Boyd R, Shelton, G Diane, Lyons, Leslie A
Published in PloS one (30.10.2014)
Published in PloS one (30.10.2014)
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Journal Article
A KCNJ10 mutation previously identified in the Russell group of terriers also occurs in Smooth-Haired Fox Terriers with hereditary ataxia and in related breeds
Rohdin, Cecilia, Gilliam, Douglas, O'Leary, Caroline A, O'Brien, Dennis P, Coates, Joan R, Johnson, Gary S, Jäderlund, Karin Hultin
Published in Acta veterinaria scandinavica (23.05.2015)
Published in Acta veterinaria scandinavica (23.05.2015)
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Journal Article
Diarrhea associated with afatinib: an oral ErbB family blocker
Yang, James Chih-Hsin, Reguart, Noemi, Barinoff, Jana, Köhler, Jens, Uttenreuther-Fischer, Martina, Stammberger, Uz, O'Brien, Dennis, Wolf, Jürgen, Cohen, Ezra EW
Published in Expert review of anticancer therapy (01.06.2013)
Published in Expert review of anticancer therapy (01.06.2013)
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Journal Article
A rare homozygous MFSD8 single-base-pair deletion and frameshift in the whole genome sequence of a Chinese Crested dog with neuronal ceroid lipofuscinosis
Guo, Juyuan, O'Brien, Dennis P, Mhlanga-Mutangadura, Tendai, Olby, Natasha J, Taylor, Jeremy F, Schnabel, Robert D, Katz, Martin L, Johnson, Gary S
Published in BMC veterinary research (03.01.2015)
Published in BMC veterinary research (03.01.2015)
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Journal Article
A mutation in the Warburg syndrome gene, RAB3GAP1 , causes a similar syndrome with polyneuropathy and neuronal vacuolation in Black Russian Terrier dogs
Mhlanga-Mutangadura, Tendai, Johnson, Gary S, Schnabel, Robert D, Taylor, Jeremy F, Johnson, Gayle C, Katz, Martin L, Shelton, G. Diane, Lever, Teresa E, Giuliano, Elizabeth, Granger, Nicolas, Shomper, Jeremy, O'Brien, Dennis P
Published in Neurobiology of disease (01.02.2016)
Published in Neurobiology of disease (01.02.2016)
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Journal Article
Canine hereditary ataxia in old english sheepdogs and gordon setters is associated with a defect in the autophagy gene encoding RAB24
Agler, Caryline, Nielsen, Dahlia M, Urkasemsin, Ganokon, Singleton, Andrew, Tonomura, Noriko, Sigurdsson, Snaevar, Tang, Ruqi, Linder, Keith, Arepalli, Sampath, Hernandez, Dena, Lindblad-Toh, Kerstin, van de Leemput, Joyce, Motsinger-Reif, Alison, O'Brien, Dennis P, Bell, Jerold, Harris, Tonya, Steinberg, Steven, Olby, Natasha J
Published in PLoS genetics (01.02.2014)
Published in PLoS genetics (01.02.2014)
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Journal Article
A CLN8 nonsense mutation in the whole genome sequence of a mixed breed dog with neuronal ceroid lipofuscinosis and Australian Shepherd ancestry
Guo, Juyuan, Johnson, Gary S., Brown, Holly A., Provencher, Michele L., da Costa, Ronaldo C., Mhlanga-Mutangadura, Tendai, Taylor, Jeremy F., Schnabel, Robert D., O'Brien, Dennis P., Katz, Martin L.
Published in Molecular genetics and metabolism (01.08.2014)
Published in Molecular genetics and metabolism (01.08.2014)
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