Impact of a baseline polymorphism on the emergence of resistance to the hepatitis C virus nonstructural protein 5a replication complex inhibitor, BMS-790052
Sun, Jin-Hua, O'Boyle II, Donald R., Zhang, Yan, Wang, Chunfu, Nower, Peter, Valera, Lourdes, Roberts, Susan, Nettles, Richard E., Fridell, Robert A., Gao, Min
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Hepatitis C Virus RNA Elimination and Development of Resistance in Replicon Cells Treated with BMS-790052
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Chemical genetics strategy identifies an HCV NS5A inhibitor with a potent clinical effect
Meanwell, Nicholas A, Gao, Min, Nettles, Richard E, Belema, Makonen, Snyder, Lawrence B, Nguyen, Van N, Fridell, Robert A, Serrano-Wu, Michael H, Langley, David R, Sun, Jin-Hua, O’Boyle II, Donald R, Lemm, Julie A, Wang, Chunfu, Knipe, Jay O, Chien, Caly, Colonno, Richard J, Grasela, Dennis M, Hamann, Lawrence G
Published in Nature (London) (06.05.2010)
Published in Nature (London) (06.05.2010)
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Characterizations of HCV NS5A replication complex inhibitors
O'Boyle II, Donald R, Sun, Jin-Hua, Nower, Peter T, Lemm, Julie A, Fridell, Robert A, Wang, Chunfu, Romine, Jeffrey L, Belema, Makonen, Nguyen, Van N, Laurent, Denis R. St, Serrano-Wu, Michael, Snyder, Lawrence B, Meanwell, Nicholas A, Langley, David R, Gao, Min
Published in Virology (New York, N.Y.) (01.09.2013)
Published in Virology (New York, N.Y.) (01.09.2013)
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Specific Inhibition of Bovine Viral Diarrhea Virus Replicase
Sun, Jin-Hua, Lemm, Julie A, O'Boyle, 2nd, Donald R, Racela, Jason, Colonno, Richard, Gao, Min
Published in Journal of Virology (01.06.2003)
Published in Journal of Virology (01.06.2003)
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Persistence of Resistant Variants in Hepatitis C Virus-Infected Patients Treated with the NS5A Replication Complex Inhibitor Daclatasvir
CHUNFU WANG, SUN, Jin-Hua, O'BOYLE, Donald R, NOWER, Peter, VALERA, Lourdes, ROBERTS, Susan, FRIDELL, Robert A, MIN GAO
Published in Antimicrobial Agents and Chemotherapy (01.05.2013)
Published in Antimicrobial Agents and Chemotherapy (01.05.2013)
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In Vitro Activity of BMS-790052 on Hepatitis C Virus Genotype 4 NS5A
Wang, Chunfu, Jia, Lingling, Huang, Haichang, Qiu, Dike, Valera, Lourdes, Huang, Xin, Sun, Jin-Hua, Nower, Peter T, O'Boyle, 2nd, Donald R, Gao, Min, Fridell, Robert A
Published in Antimicrobial Agents and Chemotherapy (01.03.2012)
Published in Antimicrobial Agents and Chemotherapy (01.03.2012)
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Discovery of Potent Hepatitis C Virus NS5A Inhibitors with Dimeric Structures
Lemm, Julie A, Leet, John E, O'Boyle, 2nd, Donald R, Romine, Jeffrey L, Huang, Xiaohua Stella, Schroeder, Daniel R, Alberts, Jeffrey, Cantone, Joseph L, Sun, Jin-Hua, Nower, Peter T, Martin, Scott W, Serrano-Wu, Michael H, Meanwell, Nicholas A, Snyder, Lawrence B, Gao, Min
Published in Antimicrobial Agents and Chemotherapy (01.08.2011)
Published in Antimicrobial Agents and Chemotherapy (01.08.2011)
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Resensitizing daclatasvir-resistant hepatitis C variants by allosteric modulation of NS5A
Sun, Jin-Hua, O’Boyle II, Donald R., Fridell, Robert A., Langley, David R., Wang, Chunfu, Roberts, Susan B., Nower, Peter, Johnson, Benjamin M., Moulin, Frederic, Nophsker, Michelle J., Wang, Ying-Kai, Liu, Mengping, Rigat, Karen, Tu, Yong, Hewawasam, Piyasena, Kadow, John, Meanwell, Nicholas A., Cockett, Mark, Lemm, Julie A., Kramer, Melissa, Belema, Makonen, Gao, Min
Published in Nature (London) (12.11.2015)
Published in Nature (London) (12.11.2015)
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Development of a Cell-Based High-Throughput Specificity Screen Using a Hepatitis C Virus-Bovine Viral Diarrhea Virus Dual Replicon Assay
O'BOYLE, Donald R, NOWER, Peter T, LEMM, Julie A, VALERA, Lourdes, SUN, Jin-Hua, RIGAT, Karen, COLONNO, Richard, MIN GAO
Published in Antimicrobial Agents and Chemotherapy (01.04.2005)
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Replication-Competent Chimeric Hepatitis C Virus Subgenomic Replicons
Lemm, Julie A., Liu, Mengping, Rose, Ronald E., Fridell, Robert, O’Boyle II, Donald R., Colonno, Richard, Gao, Min
Published in Intervirology (01.01.2005)
Published in Intervirology (01.01.2005)
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effects of NS5A inhibitors on NS5A phosphorylation, polyprotein processing and localization
Qiu, Dike, Lemm, Julie A, O’Boyle, Donald R., II, Sun, Jin-Hua, Nower, Peter T, Nguyen, Van, Hamann, Lawrence G, Snyder, Lawrence B, Deon, Daniel H, Ruediger, Edward, Meanwell, Nicholas A, Belema, Makonen, Gao, Min, Fridell, Robert A
Published in Journal of general virology (01.11.2011)
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HCV NS5A replication complex inhibitors. Part 3: discovery of potent analogs with distinct core topologies
Lopez, Omar D, Nguyen, Van N, St. Laurent, Denis R, Belema, Makonen, Serrano-Wu, Michael H, Goodrich, Jason T, Yang, Fukang, Qiu, Yuping, Ripka, Amy S, Nower, Peter T, Valera, Lourdes, Liu, Mengping, O’Boyle, Donald R., II, Sun, Jin-Hua, Fridell, Robert A, Lemm, Julie A, Gao, Min, Good, Andrew C, Meanwell, Nicholas A, Snyder, Lawrence B
Published in Bioorganic & medicinal chemistry letters (01.02.2013)
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A 96-well based analysis of replicon elimination with the HCV NS5A replication complex inhibitor daclatasvir
O’Boyle, Donald R., Nower, Peter T., Sun, Jin-Hua, Fridell, Robert, Wang, Chunfu, Valera, Lourdes, Gao, Min
Published in Journal of virological methods (01.10.2013)
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Stimulation of the Herpes Simplex Virus Type I Protease by Antichaeotrophic Salts (∗)
Yamanaka, Gregory, DiIanni, Carolyn L., O'Boyle, Donald R., Stevens, John, Weinheimer, Steven P., Deckman, Ingrid C., Matusick-Kumar, Linda, Colonno, Richard J.
Published in The Journal of biological chemistry (15.12.1995)
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INHIBITORS OF HCV REPLICATION
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inibidores de vírus da hepatite c
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Year of Publication 05.07.2016
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