G-Protein-coupled receptor oligomerization and its potential for drug discovery
George, Susan R, O'Dowd, Brian F, Lee, Samuel P
Published in Nature reviews. Drug discovery (01.10.2002)
Published in Nature reviews. Drug discovery (01.10.2002)
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Calcium signaling cascade links dopamine D1-D2 receptor heteromer to striatal BDNF production and neuronal growth
Hasbi, Ahmed, Fan, Theresa, Alijaniaram, Mohammad, Nguyen, Tuan, Perreault, Melissa L, O'Dowd, Brian F, George, Susan R
Published in Proceedings of the National Academy of Sciences - PNAS (15.12.2009)
Published in Proceedings of the National Academy of Sciences - PNAS (15.12.2009)
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D1-D2 dopamine receptor heterooligomers with unique pharmacology are coupled to rapid activation of Gq/11 in the striatum
Rashid, Asim J, So, Christopher H, Kong, Michael M.C, Furtak, Teresa, El-Ghundi, Mufida, Cheng, Regina, O'Dowd, Brian F, George, Susan R
Published in Proceedings of the National Academy of Sciences - PNAS (09.01.2007)
Published in Proceedings of the National Academy of Sciences - PNAS (09.01.2007)
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Dopamine D1-D2 receptor heteromer in dual phenotype GABA/glutamate-coexpressing striatal medium spiny neurons: regulation of BDNF, GAD67 and VGLUT1/2
Perreault, Melissa L, Fan, Theresa, Alijaniaram, Mohammed, O'Dowd, Brian F, George, Susan R
Published in PloS one (12.03.2012)
Published in PloS one (12.03.2012)
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Activation of Dopamine D1-D2 Receptor Complex Attenuates Cocaine Reward and Reinstatement of Cocaine-Seeking through Inhibition of DARPP-32, ERK, and ΔFosB
Hasbi, Ahmed, Perreault, Melissa L, Shen, Maurice Y F, Fan, Theresa, Nguyen, Tuan, Alijaniaram, Mohammed, Banasikowski, Tomek J, Grace, Anthony A, O'Dowd, Brian F, Fletcher, Paul J, George, Susan R
Published in Frontiers in pharmacology (04.01.2018)
Published in Frontiers in pharmacology (04.01.2018)
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Dopamine D1 and D2 Receptor Co-activation Generates a Novel Phospholipase C-mediated Calcium Signal
Lee, Samuel P, So, Christopher H, Rashid, Asim J, Varghese, George, Cheng, Regina, Lança, A José, O'Dowd, Brian F, George, Susan R
Published in The Journal of biological chemistry (20.08.2004)
Published in The Journal of biological chemistry (20.08.2004)
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Calcium Signaling by Dopamine D5 Receptor and D5-D2 Receptor Hetero-Oligomers Occurs by a Mechanism Distinct from That for Dopamine D1-D2 Receptor Hetero-Oligomers
So, Christopher H, Verma, Vaneeta, Alijaniaram, Mohammad, Cheng, Regina, Rashid, Asim J, O'Dowd, Brian F, George, Susan R
Published in Molecular pharmacology (01.04.2009)
Published in Molecular pharmacology (01.04.2009)
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Dopamine Receptor Homooligomers and Heterooligomers in Schizophrenia
Perreault, Melissa L., O’Dowd, Brian F., George, Susan R.
Published in CNS neuroscience & therapeutics (01.02.2011)
Published in CNS neuroscience & therapeutics (01.02.2011)
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Journal Article
Regulation of D1 Dopamine Receptor Trafficking and Signaling by Caveolin-1
Kong, Michael M. C., Hasbi, Ahmed, Mattocks, Michael, Fan, Theresa, O'Dowd, Brian F., George, Susan R.
Published in Molecular pharmacology (01.11.2007)
Published in Molecular pharmacology (01.11.2007)
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D2 Dopamine Receptor Homodimerization Is Mediated by Multiple Sites of Interaction, Including an Intermolecular Interaction Involving Transmembrane Domain 4
Lee, Samuel P, O'Dowd, Brian F, Rajaram, Ryan D, Nguyen, Tuan, George, Susan R
Published in Biochemistry (Easton) (23.09.2003)
Published in Biochemistry (Easton) (23.09.2003)
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Characterization of a Family of Endogenous Neuropeptide Ligands for the G Protein-Coupled Receptors GPR7 and GPR8
Tanaka, Hirokazu, Yoshida, Tetsuo, Miyamoto, Norimasa, Motoike, Toshiyuki, Kurosu, Hiroshi, Shibata, Kenji, Yamanaka, Akihiro, Williams, S. Clay, Richardson, James A., Tsujino, Natsuko, Garry, Mary G., Lerner, Michael R., King, David S., O'Dowd, Brian F., Sakurai, Takeshi, Yanagisawa, Masashi
Published in Proceedings of the National Academy of Sciences - PNAS (13.05.2003)
Published in Proceedings of the National Academy of Sciences - PNAS (13.05.2003)
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Journal Article
D1 and D2 Dopamine Receptors Form Heterooligomers and Cointernalize after Selective Activation of Either Receptor
So, Christopher H, Varghese, George, Curley, Kevin J, Kong, Michael M C, Alijaniaram, Mohammed, Ji, Xiaodong, Nguyen, Tuan, O'dowd, Brian F, George, Susan R
Published in Molecular pharmacology (01.09.2005)
Published in Molecular pharmacology (01.09.2005)
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Discovery of a receptor related to the galanin receptors
Lee, Dennis K, Nguyen, Tuan, O'Neill, Gary P, Cheng, Regina, Liu, Yang, Howard, Andrew D, Coulombe, Nathalie, Tan, Carina P, Tang-Nguyen, Anh-Thi, George, Susan R, O'Dowd, Brian F
Published in FEBS letters (05.03.1999)
Published in FEBS letters (05.03.1999)
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Identification of a Molecular Target of Psychosine and Its Role in Globoid Cell Formation
Im, Dong-Soon, Heise, Christopher E., Nguyen, Tuan, O'Dowd, Brian F., Lynch, Kevin R.
Published in The Journal of cell biology (16.04.2001)
Published in The Journal of cell biology (16.04.2001)
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Journal Article
Dopamine Receptor Oligomerization Visualized in Living Cells
O'Dowd, Brian F., Ji, Xiaodong, Alijaniaram, Mohammad, Rajaram, Ryan D., Kong, Michael M.C., Rashid, Asim, Nguyen, Tuan, George, Susan R.
Published in The Journal of biological chemistry (04.11.2005)
Published in The Journal of biological chemistry (04.11.2005)
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