CRTH2 Antagonist MK-7246: A Synthetic Evolution from Discovery through Development
Molinaro, Carmela, Bulger, Paul G, Lee, Ernest E, Kosjek, Birgit, Lau, Stephen, Gauvreau, Danny, Howard, Melissa E, Wallace, Debra J, O’Shea, Paul D
Published in Journal of organic chemistry (02.03.2012)
Published in Journal of organic chemistry (02.03.2012)
Get full text
Journal Article
Enantioselective Hydrogenation of N−H Imines
Hou, Guohua, Gosselin, Francis, Li, Wei, McWilliams, J. Christopher, Sun, Yongkui, Weisel, Mark, O’Shea, Paul D, Chen, Cheng-yi, Davies, Ian W, Zhang, Xumu
Published in Journal of the American Chemical Society (29.07.2009)
Published in Journal of the American Chemical Society (29.07.2009)
Get full text
Journal Article
Phosphoramidates as Steering Elements for Highly Selective Access to Complementary Imidazo[1,2‑a]pyrimidine Isomers
White, Nicholas A, Clagg, Kyle, Sirois, Lauren E, Mack, Kyle A, Al-Sayah, Mohammad A, Nack, William A, O’Shea, Paul D, Zhang, Haiming, Gosselin, Francis
Published in Organic letters (06.12.2019)
Published in Organic letters (06.12.2019)
Get full text
Journal Article
Modeling a Crowdsourced Definition of Molecular Complexity
Sheridan, Robert P, Zorn, Nicolas, Sherer, Edward C, Campeau, Louis-Charles, Chang, Charlie (Zhenyu), Cumming, Jared, Maddess, Matthew L, Nantermet, Philippe G, Sinz, Christopher J, O’Shea, Paul D
Published in Journal of chemical information and modeling (23.06.2014)
Published in Journal of chemical information and modeling (23.06.2014)
Get full text
Journal Article
A Practical Enantioselective Synthesis of Odanacatib, a Potent Cathepsin K Inhibitor, via Triflate Displacement of an α-Trifluoromethylbenzyl Triflate
O’Shea, Paul D, Chen, Cheng-yi, Gauvreau, Danny, Gosselin, Francis, Hughes, Greg, Nadeau, Christian, Volante, Ralph P
Published in Journal of organic chemistry (20.02.2009)
Published in Journal of organic chemistry (20.02.2009)
Get full text
Journal Article
Scalable Synthesis of a Prostaglandin EP4 Receptor Antagonist
Gauvreau, Danny, Dolman, Sarah J, Hughes, Greg, O’Shea, Paul D, Davies, Ian W
Published in Journal of organic chemistry (18.06.2010)
Published in Journal of organic chemistry (18.06.2010)
Get full text
Journal Article
A Practical Synthesis of m-Prostaglandin E Synthase-1 Inhibitor MK-7285
Gosselin, Francis, Lau, Stephen, Nadeau, Christian, Trinh, Thao, O’Shea, Paul D, Davies, Ian W
Published in Journal of organic chemistry (16.10.2009)
Published in Journal of organic chemistry (16.10.2009)
Get full text
Journal Article
A Practical Synthesis of Renin Inhibitor MK-1597 (ACT-178882) via Catalytic Enantioselective Hydrogenation and Epimerization of Piperidine Intermediate
Molinaro, Carmela, Shultz, Scott, Roy, Amélie, Lau, Stephen, Trinh, Thao, Angelaud, Rémy, O’Shea, Paul D, Abele, Stefan, Cameron, Mark, Corley, Ed, Funel, Jacques-Alexis, Steinhuebel, Dietrich, Weisel, Mark, Krska, Shane
Published in Journal of organic chemistry (18.02.2011)
Published in Journal of organic chemistry (18.02.2011)
Get full text
Journal Article
Practical Synthesis of a Potent Bradykinin B1 Antagonist via Enantioselective Hydrogenation of a Pyridyl N-Acyl Enamide
O’Shea, Paul D, Gauvreau, Danny, Gosselin, Francis, Hughes, Greg, Nadeau, Christian, Roy, Amélie, Shultz, C. Scott
Published in Journal of organic chemistry (19.06.2009)
Published in Journal of organic chemistry (19.06.2009)
Get full text
Journal Article
Unprecedented Catalytic Asymmetric Reduction of N−H Imines
Gosselin, Francis, O'Shea, Paul D, Roy, Stéphanie, Reamer, Robert A, Chen, Cheng-yi, Volante, Ralph P
Published in Organic letters (20.01.2005)
Published in Organic letters (20.01.2005)
Get full text
Journal Article
Convergent, Fit-For-Purpose, Kilogram-Scale Synthesis of a 5-Lipoxygenase Inhibitor
Ouellet, Stéphane G, Gauvreau, Danny, Cameron, Mark, Dolman, Sarah, Campeau, Louis-Charles, Hughes, Gregory, O’Shea, Paul D, Davies, Ian W
Published in Organic process research & development (17.02.2012)
Published in Organic process research & development (17.02.2012)
Get full text
Journal Article
Development of a Practical Synthesis of Stearoyl-CoA Desaturase (SCD1) Inhibitor MK-8245
Girardin, Mélina, Dolman, Sarah J, Lauzon, Sophie, Ouellet, Stéphane G, Hughes, Greg, Fernandez, Paul, Zhou, George, O’Shea, Paul D
Published in Organic process research & development (16.09.2011)
Published in Organic process research & development (16.09.2011)
Get full text
Journal Article
Convergent Kilo-Scale Synthesis of a Potent Renin Inhibitor for the Treatment of Hypertension
Campeau, Louis-Charles, Dolman, Sarah J, Gauvreau, Danny, Corley, Ed, Liu, Jinchu, Guidry, Erin N, Ouellet, Stéphane G, Steinhuebel, Dietrich, Weisel, Mark, O’Shea, Paul D
Published in Organic process research & development (16.09.2011)
Published in Organic process research & development (16.09.2011)
Get full text
Journal Article
Diastereoselective Reductive Amination of Aryl Trifluoromethyl Ketones and α-Amino Esters
Hughes, Greg, Devine, Paul N., Naber, John R., O'Shea, Paul D., Foster, Bruce S., McKay, Daniel J., Volante, R. P.
Published in Angewandte Chemie International Edition (01.01.2007)
Published in Angewandte Chemie International Edition (01.01.2007)
Get full text
Journal Article
Remote Electronic Control in the Regioselective Reduction of Succinimides: A Practical, Scalable Synthesis of EP4 Antagonist MF-310
Molinaro, Carmela, Gauvreau, Danny, Hughes, Gregory, Lau, Stephen, Lauzon, Sophie, Angelaud, Rémy, O’Shea, Paul D, Janey, Jacob, Palucki, Michael, Hoerrner, Scott R, Raab, Conrad E, Sidler, Rick R, Belley, Michel, Han, Yongxin
Published in Journal of organic chemistry (04.09.2009)
Published in Journal of organic chemistry (04.09.2009)
Get full text
Journal Article
A Practical Synthesis of Renin Inhibitor MK-1597 (ACT-178882) via Catalytic Enantioselective Hydrogenation and Epimerization of Piperidine Intermediate
Molinaro, Carmela, Shultz, Scott, Roy, Amelie, Lau, Stephen, Trinh, Thao, Angelaud, Remy, O’Shea, Paul D, Abele, Stefan, Cameron, Mark, Corley, Ed, Funel, Jacques-Alexis, Steinhuebel, Dietrich, Weisel, Mark, Krska, Shane
Published in Journal of organic chemistry (06.01.2012)
Published in Journal of organic chemistry (06.01.2012)
Get full text
Journal Article
Practical Synthesis of a Renin Inhibitor via a Diastereoselective Dieckmann Cyclization
Gauvreau, Danny, Hughes, Greg J, Lau, Stephen Y. W, McKay, Daniel J, O’Shea, Paul D, Sidler, Rick R, Yu, Bing, Davies, Ian W
Published in Organic letters (19.11.2010)
Published in Organic letters (19.11.2010)
Get full text
Journal Article
Preparative Scale Synthesis of the Biaryl Core of Anacetrapib via a Ruthenium-Catalyzed Direct Arylation Reaction: Unexpected Effect of Solvent Impurity on the Arylation Reaction
Ouellet, Stéphane G, Roy, Amélie, Molinaro, Carmela, Angelaud, Rémy, Marcoux, Jean-François, O’Shea, Paul D, Davies, Ian W
Published in Journal of organic chemistry (04.03.2011)
Published in Journal of organic chemistry (04.03.2011)
Get full text
Journal Article
Correction to Convergent Kilo-Scale Synthesis of a Potent Renin Inhibitor for the Treatment of Hypertension
Campeau, Louis-Charles, Dolman, Sarah J, Gauvreau, Danny, Corley, Ed, Liu, Jinchu, Guidry, Erin N, Ouellet, Stéphane G, Steinhuebel, Dietrich, Weisel, Mark, O’Shea, Paul D
Published in Organic process research & development (15.06.2012)
Published in Organic process research & development (15.06.2012)
Get full text
Journal Article