Janus kinase-targeting therapies in rheumatology: a mechanisms-based approach
Tanaka, Yoshiya, Luo, Yiming, O'Shea, John J, Nakayamada, Shingo
Published in Nature reviews. Rheumatology (01.03.2022)
Published in Nature reviews. Rheumatology (01.03.2022)
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Mechanisms Underlying Lineage Commitment and Plasticity of Helper CD4⁺ T Cells
O'Shea, John J., Paul, William E.
Published in Science (American Association for the Advancement of Science) (26.02.2010)
Published in Science (American Association for the Advancement of Science) (26.02.2010)
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Type I/II cytokines, JAKs, and new strategies for treating autoimmune diseases
Schwartz, Daniella M, Bonelli, Michael, Gadina, Massimo, O'Shea, John J
Published in Nature reviews. Rheumatology (01.01.2016)
Published in Nature reviews. Rheumatology (01.01.2016)
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Journal Article
Mechanisms of Jak/STAT signaling in immunity and disease
Villarino, Alejandro V, Kanno, Yuka, Ferdinand, John R, O'Shea, John J
Published in The Journal of immunology (1950) (01.01.2015)
Published in The Journal of immunology (1950) (01.01.2015)
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Journal Article
JAK inhibition as a therapeutic strategy for immune and inflammatory diseases
Schwartz, Daniella M, Kanno, Yuka, Villarino, Alejandro, Ward, Michael, Gadina, Massimo, O'Shea, John J
Published in Nature reviews. Drug discovery (01.01.2018)
Published in Nature reviews. Drug discovery (01.01.2018)
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Journal Article
Interleukin-2 Signaling via STAT5 Constrains T Helper 17 Cell Generation
Laurence, Arian, Tato, Cristina M., Davidson, Todd S., Kanno, Yuka, Chen, Zhi, Yao, Zhengju, Blank, Rebecca B., Meylan, Françoise, Siegel, Richard, Hennighausen, Lothar, Shevach, Ethan M., O'Shea, John J.
Published in Immunity (Cambridge, Mass.) (01.03.2007)
Published in Immunity (Cambridge, Mass.) (01.03.2007)
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Journal Article
Janus kinase inhibitors in autoimmune diseases
O'Shea, John J, Kontzias, Apostolos, Yamaoka, Kunihiro, Tanaka, Yoshiya, Laurence, Arian
Published in Annals of the rheumatic diseases (01.04.2013)
Published in Annals of the rheumatic diseases (01.04.2013)
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Journal Article
The JAK-STAT Pathway: Impact on Human Disease and Therapeutic Intervention
O'Shea, John J, Schwartz, Daniella M, Villarino, Alejandro V, Gadina, Massimo, McInnes, Iain B, Laurence, Arian
Published in Annual review of medicine (01.01.2015)
Published in Annual review of medicine (01.01.2015)
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Journal Article
Developmental Acquisition of Regulomes Underlies Innate Lymphoid Cell Functionality
Shih, Han-Yu, Sciumè, Giuseppe, Mikami, Yohei, Guo, Liying, Sun, Hong-Wei, Brooks, Stephen R., Urban, Joseph F., Davis, Fred P., Kanno, Yuka, O’Shea, John J.
Published in Cell (19.05.2016)
Published in Cell (19.05.2016)
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Journal Article
JAKs and STATs in Immunity, Immunodeficiency, and Cancer
O'Shea, John J, Holland, Steven M, Staudt, Louis M
Published in The New England journal of medicine (10.01.2013)
Published in The New England journal of medicine (10.01.2013)
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Journal Article
JAK inhibition as a therapeutic strategy for immune and inflammatory diseases
Schwartz, Daniella M, Kanno, Yuka, Villarino, Alejandro, Ward, Michael, Gadina, Massimo, O'Shea, John J
Published in Nature reviews. Drug discovery (01.12.2017)
Published in Nature reviews. Drug discovery (01.12.2017)
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Journal Article
SnapShot: Jak-STAT Signaling II
Villarino, Alejandro V., Gadina, Massimo, O’Shea, John J., Kanno, Yuka
Published in Cell (25.06.2020)
Published in Cell (25.06.2020)
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Journal Article
Neuropeptide CGRP Limits Group 2 Innate Lymphoid Cell Responses and Constrains Type 2 Inflammation
Nagashima, Hiroyuki, Mahlakõiv, Tanel, Shih, Han-Yu, Davis, Fred P., Meylan, Francoise, Huang, Yuefeng, Harrison, Oliver J., Yao, Chen, Mikami, Yohei, Urban, Joseph F., Caron, Kathleen M., Belkaid, Yasmine, Kanno, Yuka, Artis, David, O’Shea, John J.
Published in Immunity (Cambridge, Mass.) (15.10.2019)
Published in Immunity (Cambridge, Mass.) (15.10.2019)
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Journal Article
STAT3 Transcription Factor Promotes Instability of nTreg Cells and Limits Generation of iTreg Cells during Acute Murine Graft-versus-Host Disease
Laurence, Arian, Amarnath, Shoba, Mariotti, Jacopo, Kim, Yong Chan, Foley, Jason, Eckhaus, Michael, O'Shea, John J., Fowler, Daniel H.
Published in Immunity (Cambridge, Mass.) (24.08.2012)
Published in Immunity (Cambridge, Mass.) (24.08.2012)
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