Constitutive Autophagy and Nucleophagy during Epidermal Differentiation
Akinduro, Olufolake, Sully, Katherine, Patel, Ankit, Robinson, Deborah J., Chikh, Anissa, McPhail, Graham, Braun, Kristin M., Philpott, Michael P., Harwood, Catherine A., Byrne, Carolyn, O'Shaughnessy, Ryan F.L., Bergamaschi, Daniele
Published in Journal of investigative dermatology (01.07.2016)
Published in Journal of investigative dermatology (01.07.2016)
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Journal Article
A mechanistic target of rapamycin complex 1/2 (mTORC1)/V-Akt murine thymoma viral oncogene homolog 1 (AKT1)/cathepsin H axis controls filaggrin expression and processing in skin, a novel mechanism for skin barrier disruption in patients with atopic dermatitis
Naeem, Aishath S., PhD, Tommasi, Cristina, MRes, Cole, Christian, PhD, Brown, Stuart J., PhD, Zhu, Yanan, PhD, Way, Benjamin, MA, BMBCh, MSc, MRCS, Willis Owen, Saffron A.G., DPhil, Moffatt, Miriam, DPhil, Cookson, William O., DPhil, Harper, John I., MBBS, MD, FRCP, FRCPCH, Di, Wei-Li, PhD, Brown, Sara J., MD, FRCPE, Reinheckel, Thomas, PhD, O'Shaughnessy, Ryan F.L., PhD
Published in Journal of allergy and clinical immunology (01.04.2017)
Published in Journal of allergy and clinical immunology (01.04.2017)
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Journal Article
Persistent kallikrein 5 activation induces atopic dermatitis-like skin architecture independent of PAR2 activity
Zhu, Yanan, PhD, Underwood, Joanne, PhD, Macmillan, Derek, PhD, Shariff, Leila, PhD, O'Shaughnessy, Ryan, PhD, Harper, John I., MD, FRCP, FRCPCH, Pickard, Chris, PhD, Friedmann, Peter S., MD, FRCP, FMedSci, Healy, Eugene, MB, PhD, FRCP, FRSB, Di, Wei-Li, MBBS, PhD
Published in Journal of allergy and clinical immunology (01.11.2017)
Published in Journal of allergy and clinical immunology (01.11.2017)
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Journal Article
Insight from the Air–Skin Interface
O'Shaughnessy, Ryan F.L., Brown, Sara J.
Published in Journal of investigative dermatology (01.02.2015)
Published in Journal of investigative dermatology (01.02.2015)
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Journal Article
Cutaneous human papillomaviruses down-regulate AKT1, whereas AKT2 up-regulation and activation associates with tumors
O'SHAUGHNESSY, Ryan F. L, AKGUL, Baki, STOREY, Alan, PFISTER, Herbert, HARWOOD, Catherine A, BYRNE, Carolyn
Published in Cancer research (Chicago, Ill.) (01.09.2007)
Published in Cancer research (Chicago, Ill.) (01.09.2007)
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Journal Article
Identifying a Hyperkeratosis Signature in Autosomal Recessive Congenital Ichthyosis: Mdm2 Inhibition Prevents Hyperkeratosis in a Rat ARCI Model
Youssef, Gehad, Ono, Masahiro, Brown, Stuart J., Kinsler, Veronica A., Sebire, Neil J., Harper, John I., O'Shaughnessy, Ryan F.L.
Published in Journal of investigative dermatology (01.03.2014)
Published in Journal of investigative dermatology (01.03.2014)
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Journal Article
Interleukin-1 alpha blockade prevents hyperkeratosis in an in vitro model of lamellar ichthyosis
O'Shaughnessy, Ryan F.L., Choudhary, Ishaan, Harper, John I.
Published in Human molecular genetics (01.07.2010)
Published in Human molecular genetics (01.07.2010)
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Journal Article
TALE homeodomain proteins regulate site-specific terminal differentiation, LCE genes and epidermal barrier
Jackson, Ben, Brown, Stuart J, Avilion, Ariel A, O'Shaughnessy, Ryan F L, Sully, Katherine, Akinduro, Olufolake, Murphy, Mark, Cleary, Michael L, Byrne, Carolyn
Published in Journal of cell science (15.05.2011)
Published in Journal of cell science (15.05.2011)
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Journal Article
Sonic Hedgehog signaling limits atopic dermatitis via Gli2-driven immune regulation
Papaioannou, Eleftheria, Yánez, Diana C, Ross, Susan, Lau, Ching-In, Solanki, Anisha, Chawda, Mira Manilal, Virasami, Alex, Ranz, Ismael, Ono, Masahiro, O'Shaughnessy, Ryan F L, Crompton, Tessa
Published in The Journal of clinical investigation (01.08.2019)
Published in The Journal of clinical investigation (01.08.2019)
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Journal Article
T-Cell Reconstitution after Thymus Xenotransplantation Induces Hair Depigmentation and Loss
Furmanski, Anna L., O'Shaughnessy, Ryan F.L., Saldana, Jose Ignacio, Blundell, Michael P., Thrasher, Adrian J., Sebire, Neil J., Davies, E. Graham, Crompton, Tessa
Published in Journal of investigative dermatology (01.05.2013)
Published in Journal of investigative dermatology (01.05.2013)
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Journal Article
Akt1-associated actomyosin remodelling is required for nuclear lamina dispersal and nuclear shrinkage in epidermal terminal differentiation
Rogerson, Clare, Wotherspoon, Duncan J., Tommasi, Cristina, Button, Robert W., O’Shaughnessy, Ryan F. L.
Published in Cell death and differentiation (01.06.2021)
Published in Cell death and differentiation (01.06.2021)
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Journal Article
Chronic activation of Toll-like receptor 2 induces an ichthyotic skin phenotype
Tagoe, Hephzi, Hassan, Sakinah, Bliss, Emily, Youssef, Gehad, Heywood, Wendy, Mills, Kevin, Harper, John I, O'Shaughnessy, Ryan F L
Published in British journal of dermatology (1951) (07.07.2023)
Published in British journal of dermatology (1951) (07.07.2023)
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Journal Article
The WNT Signalling Modulator, Wise, is Expressed in an Interaction-Dependent Manner During Hair-Follicle Cycling
O'Shaughnessy, Ryan F.L., Yeo, Weeteck, Gautier, Jean, Jahoda, Colin A.B., Christiano, Angela M.
Published in Journal of investigative dermatology (01.10.2004)
Published in Journal of investigative dermatology (01.10.2004)
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Journal Article
Phosphoinositide 3-Kinase-Dependent Signalling Pathways in Cutaneous Squamous Cell Carcinomas
Janus, Joanna M, O'Shaughnessy, Ryan F L, Harwood, Catherine A, Maffucci, Tania
Published in Cancers (11.07.2017)
Published in Cancers (11.07.2017)
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Journal Article