Discovery of Small-Molecule Selective mTORC1 Inhibitors via Direct Inhibition of Glucose Transporters
Kang, Seong A, O'Neill, David J, Machl, Andreas W, Lumpkin, Casey J, Galda, Stephanie N, Sengupta, Shomit, Mahoney, Sarah J, Howell, Jessica J, Molz, Lisa, Hahm, Seung, Vlasuk, George P, Saiah, Eddine
Published in Cell chemical biology (19.09.2019)
Published in Cell chemical biology (19.09.2019)
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Discovery of Novel Selective Norepinephrine Inhibitors: 1-(2-Morpholin-2-ylethyl)-3-aryl-1,3-dihydro-2,1,3-benzothiadiazole 2,2-Dioxides (WYE-114152)
O’Neill, David J, Adedoyin, Adedayo, Bray, Jenifer A, Deecher, Darlene C, Fensome, Andrew, Goldberg, Joel A, Harrison, Jim, Leventhal, Liza, Mann, Charles, Mark, Lilly, Nogle, Lisa, Sullivan, Nicole R, Spangler, Taylor B, Terefenko, Eugene A, Trybulski, Eugene J, Uveges, Albert J, Vu, An, Whiteside, Garth T, Zhang, Puwen
Published in Journal of medicinal chemistry (13.10.2011)
Published in Journal of medicinal chemistry (13.10.2011)
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Discovery of Novel Selective Norepinephrine Reuptake Inhibitors: 4-[3-Aryl-2,2-dioxido-2,1,3-benzothiadiazol-1(3H)-yl]-1-(methylamino)butan-2-ols (WYE-103231)
O’Neill, David J, Adedoyin, Adedayo, Alfinito, Peter D, Bray, Jenifer A, Cosmi, Scott, Deecher, Darlene C, Fensome, Andrew, Harrison, Jim, Leventhal, Liza, Mann, Charles, McComas, Casey C, Sullivan, Nicole R, Spangler, Taylor B, Uveges, Albert J, Trybulski, Eugene J, Whiteside, Garth T, Zhang, Puwen
Published in Journal of medicinal chemistry (10.06.2010)
Published in Journal of medicinal chemistry (10.06.2010)
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Synthesis and Discovery of Macrocyclic Polyoxygenated Bis-7-azaindolylmaleimides as a Novel Series of Potent and Highly Selective Glycogen Synthase Kinase-3β Inhibitors
Kuo, Gee-Hong, Prouty, Catherine, DeAngelis, Alan, Shen, Lan, O'Neill, David J, Shah, Chandra, Connolly, Peter J, Murray, William V, Conway, Bruce R, Cheung, Peter, Westover, Lori, Xu, Jun Z, Look, Richard A, Demarest, Keith T, Emanuel, Stuart, Middleton, Steven A, Jolliffe, Linda, Beavers, Mary Pat, Chen, Xin
Published in Journal of medicinal chemistry (11.09.2003)
Published in Journal of medicinal chemistry (11.09.2003)
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Design, synthesis, and biological evaluation of novel 7-azaindolyl-heteroaryl-maleimides as potent and selective glycogen synthase kinase-3β (GSK-3β) inhibitors
O'Neill, David J., Shen, Lan, Prouty, Catherine, Conway, Bruce R., Westover, Lori, Xu, Jun Z., Zhang, Han-Cheng, Maryanoff, Bruce E., Murray, William V., Demarest, Keith T., Kuo, Gee-Hong
Published in Bioorganic & medicinal chemistry (15.06.2004)
Published in Bioorganic & medicinal chemistry (15.06.2004)
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Journal Article
Design, synthesis, and biological evaluation of novel 7-azaindolyl-heteroaryl-maleimides as potent and selective glycogen synthase kinase-3beta (GSK-3beta) inhibitors
O'Neill, David J, Shen, Lan, Prouty, Catherine, Conway, Bruce R, Westover, Lori, Xu, Jun Z, Zhang, Han-Cheng, Maryanoff, Bruce E, Murray, William V, Demarest, Keith T, Kuo, Gee-Hong
Published in Bioorganic & medicinal chemistry (15.06.2004)
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Published in Bioorganic & medicinal chemistry (15.06.2004)
Journal Article
Design, synthesis, and biological evaluation of novel 7-azaindolyl-heteroaryl-maleimides as potent and selective glycogen synthase kinase-3β (GSK-3β) inhibitors
O'NEILL, David J, LAN SHEN, KUO, Gee-Hong, PROUTY, Catherine, CONWAY, Bruce R, WESTOVER, Lori, XU, Jun Z, ZHANG, Han-Cheng, MARYANOFF, Bruce E, MURRAY, William V, DEMAREST, Keith T
Published in Bioorganic & medicinal chemistry (01.06.2004)
Published in Bioorganic & medicinal chemistry (01.06.2004)
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Synthesis and discovery of macrocyclic polyoxygenated bis-7-azaindolylmaleimides as a novel series of potent and highly selective glycogen synthase kinase-3beta inhibitors
Kuo, Gee-Hong, Prouty, Catherine, DeAngelis, Alan, Shen, Lan, O'Neill, David J, Shah, Chandra, Connolly, Peter J, Murray, William V, Conway, Bruce R, Cheung, Peter, Westover, Lori, Xu, Jun Z, Look, Richard A, Demarest, Keith T, Emanuel, Stuart, Middleton, Steven A, Jolliffe, Linda, Beavers, Mary Pat, Chen, Xin
Published in Journal of medicinal chemistry (11.09.2003)
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Published in Journal of medicinal chemistry (11.09.2003)
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