502 Pembrolizumab (MK-3475) for patients (pts) with advanced colorectal carcinoma (CRC): Preliminary results from KEYNOTE-028
O'Neil, B.H, Wallmark, J, Lorente, D, Elez, E, Raimbourg, J, Gomez-Roca, C, Ejadi, S, Piha-Paul, S.A, Moss, R.A, Siu, L.L, Dotti, K, Santoro, A, Gould, M, Yuan, S.S, Koshiji, M, Han, S.W
Published in European journal of cancer (1990) (01.09.2015)
Published in European journal of cancer (1990) (01.09.2015)
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37P Phase II results of the porcupine (PORCN) inhibitor zamaporvint (RXC004) in genetically selected microsatellite stable colorectal cancer patients
Cook, N., Bridgewater, J.A., Saunders, M.P., Kopetz, S., Garcia-Carbonero, R., Beom, S-H., O'Neil, B.H., Wilson, R.H., Graham, J., Maurel, J., Kim, T.W., Chau, I., Saleha, S., Goodwin, L., Wilson, D., Robertson, J., Timmis, H., Asken, E., Woodcock, S.A., Morris, V.
Published in Annals of oncology (01.06.2024)
Published in Annals of oncology (01.06.2024)
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Long-Term Survival and Local Control Outcomes in Oligometastatic Colorectal Cancer Treated with Liver Stereotactic Body Radiation Therapy Long-Term Survival and Local Control Outcomes in Oligometastatic Colorectal Cancer
Hinton, J., Galle, J.O., Long, D., Deig, C., Kong, F.M., Maluccio, M., Shahda, S., O'Neil, B.H., Ellsworth, S.G.
Published in International journal of radiation oncology, biology, physics (01.11.2018)
Published in International journal of radiation oncology, biology, physics (01.11.2018)
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Kinetics and Dosimetric Predictors of Acute Radiation-Induced Lymphopenia in Pancreatic Cancer
Ellsworth, S.G., Mereniuk, T., Zhang, H., Grossman, S., O'Neil, B.H., Hobbs, R.F., Shahda, S., Mohan, R., Kong, F.M., Jin, J.Y.
Published in International journal of radiation oncology, biology, physics (01.11.2018)
Published in International journal of radiation oncology, biology, physics (01.11.2018)
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Long-Term Survival and Local Control Outcomes in Oligometastatic Colorectal Cancer Treated with Liver Stereotactic Body Radiation Therapy
Hinton, J., Agrawal, N., Rhome, R.M., Long, D., Galle, J.O., Burney, H., O'Neil, B.H., Zang, Y., Maluccio, M., Shahda, S., Ellsworth, S.G.
Published in International journal of radiation oncology, biology, physics (01.09.2019)
Published in International journal of radiation oncology, biology, physics (01.09.2019)
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A phase II/III randomized study to compare the efficacy and safety of rigosertib plus gemcitabine versus gemcitabine alone in patients with previously untreated metastatic pancreatic cancer
O'Neil, B H, Scott, A J, Ma, W W, Cohen, S J, Aisner, D L, Menter, A R, Tejani, M A, Cho, J K, Granfortuna, J, Coveler, L, Olowokure, O O, Baranda, J C, Cusnir, M, Phillip, P, Boles, J, Nazemzadeh, R, Rarick, M, Cohen, D J, Radford, J, Fehrenbacher, L, Bajaj, R, Bathini, V, Fanta, P, Berlin, J, McRee, A J, Maguire, R, Wilhelm, F, Maniar, M, Jimeno, A, Gomes, C L, Messersmith, W A
Published in Annals of oncology (01.09.2015)
Published in Annals of oncology (01.09.2015)
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Phase 1b/2 Study of Neoadjuvant Chemoradiation Therapy With CRLX101 and Capecitabine for Locally Advanced Rectal Cancer
Moon, D.H., McRee, A.J., Blackstock, A.W., O'Neil, B.H., Moore, D.T., Calvo, B.F., Lee, M.S., Murphy, C., Caliri, K., Tynan, M.T., Senderowicz, A.M., Tepper, J.E., Sanoff, H.K., Wang, A.Z.
Published in International journal of radiation oncology, biology, physics (01.10.2017)
Published in International journal of radiation oncology, biology, physics (01.10.2017)
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Relationship of PD-L1 and a T-cell inflamed gene expression profile (GEP) to clinical response in a multicohort trial of solid tumors (KEYNOTE [KN]028)
Ott, P.A., Bang, Y-J., Razak, A.R.A., Bennouna, J., Soria, J-C., Rugo, H.S., Cohen, R.B., O'Neil, B.H., Mehnert, J.M., Lopez, J., Doi, T., van Brummelen, E., Levitan, D., Zhao, G., Emancipator, K., Stein, K., Joe, A., Ayers, M., Lunceford, J., Piha-Paul, S.A.
Published in Annals of oncology (01.09.2017)
Published in Annals of oncology (01.09.2017)
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Pembrolizumab for patients with PD-L1–positive advanced carcinoid or pancreatic neuroendocrine tumors: Results from the KEYNOTE-028 study
Mehnert, J.M., Rugo, H.S., O'Neil, B.H., Santoro, A., Schellens, J.H.M., Cohen, R.B., Doi, T., Ott, P.A., Pishvaian, M.J., Puzanov, I., Aung, K.L., Hsu, C., Le Tourneau, C., Soria, J-C., Elez, E., Tamura, K., Gould, M., Zhao, G., Stein, K., Piha-Paul, S.A.
Published in Annals of oncology (01.09.2017)
Published in Annals of oncology (01.09.2017)
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Journal Article
A phase II/III randomized study to compare the efficacy and safety of rigosertib plus gemcitabine versus gemcitabine alone in patients with previously untreated metastatic pancreatic cancer
O'Neil, B.H., Scott, A.J., Ma, W.W., Cohen, S.J., Aisner, D.L., Menter, A.R., Tejani, M.A., Cho, J.K., Granfortuna, J., Coveler, A.L., Olowokure, O.O., Baranda, J.C., Cusnir, M., Phillip, P., Boles, J., Nazemzadeh, R., Rarick, M., Cohen, D.J., Radford, J., Fehrenbacher, L., Bajaj, R., Bathini, V., Fanta, P., Berlin, J., McRee, A.J., Maguire, R., Wilhelm, F., Maniar, M., Jimeno, A., Gomes, C.L., Messersmith, W.A.
Published in Annals of oncology (01.06.2016)
Published in Annals of oncology (01.06.2016)
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501OCALGB/SWOG 80405: PHASE III TRIAL OF IRINOTECAN/5-FU/LEUCOVORIN (FOLFIRI) OR OXALIPLATIN/5-FU/LEUCOVORIN (MFOLFOX6) WITH BEVACIZUMAB (BV) OR CETUXIMAB (CET) FOR PATIENTS (PTS) WITH EXPANDED RAS ANALYSES UNTREATED METASTATIC ADENOCARCINOMA OF THE COLON OR RECTUM (MCRC)
Lenz, H., Niedzwiecki, D., Innocenti, F., Blanke, C., Mahony, M.R., O'Neil, B.H., Shaw, J.E., Polite, B., Hochster, H., Atkins, J., Goldberg, R., Mayer, R., Schilsky, R.L., Bertagnolli, M., Venook, A.
Published in Annals of oncology (01.09.2014)
Published in Annals of oncology (01.09.2014)
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Calgb/Swog 80405: Phase III Trial of Irinotecan/5-Fu/Leucovorin (Folfiri) or Oxaliplatin/5-Fu/Leucovorin (Mfolfox6) with Bevacizumab (Bv) or Cetuximab (Cet) for Patients (Pts) with Expanded Ras Analyses Untreated Metastatic Adenocarcinoma of the Colon Or Rectum (Mcrc)
Lenz, H., Niedzwiecki, D., Innocenti, F., Blanke, C., Mahony, M.R., O'Neil, B.H., Shaw, J.E., Polite, B., Hochster, H., Atkins, J., Goldberg, R., Mayer, R., Schilsky, R.L., Bertagnolli, M., Venook, A.
Published in Annals of oncology (01.09.2014)
Published in Annals of oncology (01.09.2014)
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A phase II/III randomized study to compare the efficacy and safety of rigosertib plus gemcitabine versus gemcitabine alone in patients with previously untreated metastatic pancreatic cancer††This work was previously presented as an abstract at the 2015 Gastrointestinal Cancer Symposium, San Francisco, CA, USA, on 16 January 2015
O'Neil, B.H., Scott, A.J., Ma, W.W., Cohen, S.J., Aisner, D.L., Menter, A.R., Tejani, M.A., Cho, J.K., Granfortuna, J., Coveler, L., Olowokure, O.O., Baranda, J.C., Cusnir, M., Phillip, P., Boles, J., Nazemzadeh, R., Rarick, M., Cohen, D.J., Radford, J., Fehrenbacher, L., Bajaj, R., Bathini, V., Fanta, P., Berlin, J., McRee, A.J., Maguire, R., Wilhelm, F., Maniar, M., Jimeno, A., Gomes, C.L., Messersmith, W.A.
Published in Annals of oncology (01.09.2015)
Published in Annals of oncology (01.09.2015)
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Journal Article
A phase II/III randomized study to compare the efficacy and safety of rigosertib plus gemcitabine versus gemcitabine alone in patients with previously untreated metastatic pancreatic cancer
O'Neil, B.H., Scott, A.J., Ma, W.W., Cohen, S.J., Leichman, L., Aisner, D.L., Menter, A.R., Tejani, M.A., Cho, J.K., Granfortuna, J., Coveler, L., Olowokure, O.O., Baranda, J.C., Cusnir, M., Phillip, P., Boles, J., Nazemzadeh, R., Rarick, M., Cohen, D.J., Radford, J., Fehrenbacher, L., Bajaj, R., Bathini, V., Fanta, P., Berlin, J., McRee, A.J., Maguire, R., Wilhelm, F., Maniar, M., Jimeno, A., Gomes, C.L., Messersmith, W.A.
Published in Annals of oncology (01.12.2015)
Published in Annals of oncology (01.12.2015)
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614MO Type II RAF inhibitor tovorafenib in recurrent/refractory (R/R) melanoma or other solid tumors with RAF fusions and/or RAF1 amplification
Vieito, M., Garralda, E., Mehmi, I., Gaudy Marqueste, C., O’Neil, B.H., Medina, T.M., Body, A., Arance, A.M., Kummar, S., Najjar, Y.G., Bedard, P.L., Chu, C., McKenna, C., Hume, S., Kopp, L.M., Lee, J.
Published in Annals of oncology (01.09.2024)
Published in Annals of oncology (01.09.2024)
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CN13 Impact of AI clinical trial program on screening, matching, and enrollment of patients over 6 months
Shepard, D., Mallahan, S., Osterman, C., Skelly, D., Patnaude, E., Weiss, M., O’Neil, B.H., Rao, A., Abdulla, N.E., Zarzour, A., Sankhala, K. Kumar, Goldstein, M.G., Parsons, B., La Porte, P., Franzen, A.G., Cohen, E., Cooney, M.
Published in Annals of oncology (01.09.2024)
Published in Annals of oncology (01.09.2024)
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604O Phase I dose escalation and initial dose expansion results of AMG 193: A MTA-cooperative PRMT5 inhibitor, in patients (pts) with MTAP-deleted solid tumors
Sacher, A.G., Villalona-Calero, M., O’Neil, B.H., Rodon, J., Doi, T., Postel-Vinay, S., Ghiringhelli, F., Yamamoto, N., Wahlroos, S., Villaruz, L., El-Helali, A., Fujiwara, Y., Addeo, A., Lin, C-C., Fontana, E., Chuang, C-H., Liu, C., Eggert, T., Penel, N., Prenen, H.
Published in Annals of oncology (01.09.2024)
Published in Annals of oncology (01.09.2024)
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First-in-human study of AMG 193, an MTA-cooperative PRMT5 inhibitor, in patients with MTAP-deleted solid tumors: results from phase I dose exploration
Rodon, J., Prenen, H., Sacher, A., Villalona-Calero, M., Penel, N., El Helali, A., Rottey, S., Yamamoto, N., Ghiringhelli, F., Goebeler, M.E., Doi, T., Postel-Vinay, S., Lin, C.-C., Liu, C., Chuang, C.-H., Keyvanjah, K., Eggert, T., O’Neil, B.H.
Published in Annals of oncology (16.09.2024)
Published in Annals of oncology (16.09.2024)
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Phase 1b/II study of cancer stemness inhibitor napabucasin in combination with FOLFIRI +/− bevacizumab (bev) in metastatic colorectal cancer (mCRC) patients (pts)
Bendell, J., Hubbard, J., O’Neil, B.H., Jonker, D., Starodub, A., Peyton, J., Pitot, H., Halfdanarson, T., Nadeau, B., Zubkus, J., Adesunloye, B., Edenfield, J., Li, Y.Z., Li, W., Grothey, A., Borodyansky, L., Li, C.J.
Published in Annals of oncology (01.06.2017)
Published in Annals of oncology (01.06.2017)
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