Selection of high-affinity Centyrin FN3 domains from a simple library diversified at a combination of strand and loop positions
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Published in Protein engineering, design and selection (01.10.2014)
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Protein Engineering Strategies for Sustained Glucagon-Like Peptide-1 Receptor–Dependent Control of Glucose Homeostasis
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Protein Design: A Hierarchic Approach
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Evaluation of a Centyrin-Based Near-Infrared Probe for Fluorescence-Guided Surgery of Epidermal Growth Factor Receptor Positive Tumors
Mahalingam, Sakkarapalayam M, Dudkin, Vadim Y, Goldberg, Shalom, Klein, Donna, Yi, Fang, Singhal, Sunil, O’Neil, Karyn T, Low, Philip S
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Fusion to a highly stable consensus albumin binding domain allows for tunable pharmacokinetics
Jacobs, Steven A., Gibbs, Alan C., Conk, Michelle, Yi, Fang, Maguire, Diane, Kane, Colleen, O'Neil, Karyn T.
Published in Protein engineering, design and selection (01.10.2015)
Published in Protein engineering, design and selection (01.10.2015)
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Engineering a targeted delivery platform using Centyrins
Goldberg, Shalom D, Cardoso, Rosa M F, Lin, Tricia, Spinka-Doms, Tracy, Klein, Donna, Jacobs, Steven A, Dudkin, Vadim, Gilliland, Gary, O'Neil, Karyn T
Published in Protein engineering, design and selection (01.12.2016)
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Mechanisms of self-association of a human monoclonal antibody CNTO607
Bethea, Deidra, Wu, Sheng-Jiun, Luo, Jinquan, Hyun, Linus, Lacy, Eilyn R., Teplyakov, Alexey, Jacobs, Steven A., O'Neil, Karyn T., Gilliland, Gary L., Feng, Yiqing
Published in Protein engineering, design and selection (01.10.2012)
Published in Protein engineering, design and selection (01.10.2012)
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Conformational flexibility of an anti-IL-13 DARPin
Teplyakov, Alexey, Malia, Thomas J, Obmolova, Galina, Jacobs, Steven A, O'Neil, Karyn T, Gilliland, Gary L
Published in Protein engineering, design and selection (01.01.2017)
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Structure-based engineering of a monoclonal antibody for improved solubility
Wu, Sheng-Jiun, Luo, Jinquan, O'Neil, Karyn T., Kang, James, Lacy, Eilyn R., Canziani, Gabriela, Baker, Audrey, Huang, Maggie, Tang, Qing Mike, Raju, T.Shantha, Jacobs, Steven A., Teplyakov, Alexey, Gilliland, Gary L., Feng, Yiqing
Published in Protein engineering, design and selection (01.08.2010)
Published in Protein engineering, design and selection (01.08.2010)
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Design of novel FN3 domains with high stability by a consensus sequence approach
Jacobs, Steven A., Diem, Michael D., Luo, Jinquan, Teplyakov, Alexey, Obmolova, Galina, Malia, Thomas, Gilliland, Gary L., O'Neil, Karyn T.
Published in Protein engineering, design and selection (01.03.2012)
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Induced conformational change in human IL-4 upon binding of a signal-neutralizing DARPin
Obmolova, Galina, Teplyakov, Alexey, Malia, Thomas J., Keough, Edward, Luo, Jinquan, Sweet, Raymond, Jacobs, Steven A., Yi, Fang, Hippensteel, Randi, O'Neil, Karyn T., Gilliland, Gary L.
Published in Proteins, structure, function, and bioinformatics (01.06.2015)
Published in Proteins, structure, function, and bioinformatics (01.06.2015)
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C-terminal β-strand swapping in a consensus-derived fibronectin Type III scaffold
Teplyakov, Alexey, Obmolova, Galina, Malia, Thomas J., Luo, Jinquan, Jacobs, Steven A., Chan, Winnie, Domingo, Derrick, Baker, Audrey, O'Neil, Karyn T., Gilliland, Gary L.
Published in Proteins, structure, function, and bioinformatics (01.07.2014)
Published in Proteins, structure, function, and bioinformatics (01.07.2014)
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N-terminal β-strand swapping in a consensus-derived alternative scaffold driven by stabilizing hydrophobic interactions
Luo, Jinquan, Teplyakov, Alexey, Obmolova, Galina, Malia, Thomas J., Chan, Winnie, Jacobs, Steven A., O'Neil, Karyn T., Gilliland, Gary L.
Published in Proteins, structure, function, and bioinformatics (01.07.2014)
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DNA-induced increase in the .alpha.-helical content of C/EBP and GCN4
O'Neil, Karyn T, Shuman, Jon D, Ampe, Christophe, DeGrado, William F
Published in Biochemistry (Easton) (17.09.1991)
Published in Biochemistry (Easton) (17.09.1991)
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NADLER STEVEN G, ADDIS RUSSEL C, XIN YAO, DRUZINA ZHANNA, O'NEIL KARYN T, KOLAKOWSKI ROBERT V
Year of Publication 13.03.2024
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FN3 도메인-시르나 접합체 및 이의 용도
KULKARNI SWAPNIL, NADLER STEVEN G, XIN YAO, ANDERSON STEPHEN J, ADDIS RUSSELL C, DRUZINA ZHANNA, O'NEIL KARYN T, KOLAKOWSKI ROBERT V
Year of Publication 08.03.2024
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Aspartyl β-Hydroxylase (Asph) and an Evolutionarily Conserved Isoform of Asph Missing the Catalytic Domain Share Exons with Junctin
Dinchuk, Joseph E., Henderson, Nancy L., Burn, Timothy C., Huber, Reid, Ho, Siew Peng, Link, John, O'Neil, Karyn T, Focht, Richard J., Scully, Michael S., Hollis, Jeannine M., Hollis, Gregory F., Friedman, Paul A.
Published in The Journal of biological chemistry (15.12.2000)
Published in The Journal of biological chemistry (15.12.2000)
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