A phase 1 trial of vadastuximab talirine as monotherapy in patients with CD33-positive acute myeloid leukemia
Stein, Eytan M., Walter, Roland B., Erba, Harry P., Fathi, Amir T., Advani, Anjali S., Lancet, Jeffrey E., Ravandi, Farhad, Kovacsovics, Tibor, DeAngelo, Daniel J., Bixby, Dale, Faderl, Stefan, Jillella, Anand P., Ho, Phoenix A., O'Meara, Megan M., Zhao, Baiteng, Biddle-Snead, Charles, Stein, Anthony S.
Published in Blood (25.01.2018)
Published in Blood (25.01.2018)
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Brentuximab vedotin combined with ABVD or AVD for patients with newly diagnosed Hodgkin's lymphoma: a phase 1, open-label, dose-escalation study
Younes, Anas, Dr, Connors, Joseph M, Prof, Park, Steven I, MD, Fanale, Michelle, MD, O'Meara, Megan M, MD, Hunder, Naomi N, MD, Huebner, Dirk, MD, Ansell, Stephen M, Prof
Published in The lancet oncology (01.12.2013)
Published in The lancet oncology (01.12.2013)
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A phase 1 trial of vadastuximab talirine combined with hypomethylating agents in patients with CD33-positive AML
Fathi, Amir T., Erba, Harry P., Lancet, Jeffrey E., Stein, Eytan M., Ravandi, Farhad, Faderl, Stefan, Walter, Roland B., Advani, Anjali S., DeAngelo, Daniel J., Kovacsovics, Tibor J., Jillella, Anand, Bixby, Dale, Levy, Moshe Y., O'Meara, Megan M., Ho, Phoenix A., Voellinger, Jenna, Stein, Anthony S.
Published in Blood (13.09.2018)
Published in Blood (13.09.2018)
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Immunization against HIF-1α Inhibits the Growth of Basal Mammary Tumors and Targets Mammary Stem Cells In Vivo
Cecil, Denise L, Slota, Meredith, O'Meara, Megan M, Curtis, Benjamin C, Gad, Ekram, Dang, Yushe, Herendeen, Daniel, Rastetter, Lauren, Disis, Mary L
Published in Clinical cancer research (01.07.2017)
Published in Clinical cancer research (01.07.2017)
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Brentuximab vedotin in patients aged 60 years or older with relapsed or refractory CD30-positive lymphomas: a retrospective evaluation of safety and efficacy
Gopal, Ajay K., Bartlett, Nancy L., Forero-Torres, Andres, Younes, Anas, Chen, Robert, Friedberg, Jonathan W., Matous, Jeffrey V., Shustov, Andrei R., Smith, Scott E., Zain, Jasmine, O'Meara, Megan M., Fanale, Michelle A.
Published in Leukemia & lymphoma (01.10.2014)
Published in Leukemia & lymphoma (01.10.2014)
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A Multiantigen Vaccine Targeting Neu, IGFBP-2, and IGF-IR Prevents Tumor Progression in Mice with Preinvasive Breast Disease
DISIS, Mary L, GAD, Ekram, HERENDEEN, Daniel R, PHAN-LAI, Vy, KYONG HWA PARK, CECIL, Denise L, O'MEARA, Megan M, TREUTING, Piper M, LUBET, Ronald A
Published in Cancer prevention research (Philadelphia, Pa.) (01.12.2013)
Published in Cancer prevention research (Philadelphia, Pa.) (01.12.2013)
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Interim Analysis of a Phase 1 Trial of SGN-CD33A in Patients with CD33-Positive Acute Myeloid Leukemia (AML)
Stein, Eytan M., Stein, Anthony, Walter, Roland B., Fathi, Amir T., Lancet, Jeffrey E., Kovacsovics, Tibor J., Advani, Anjali S., DeAngelo, Daniel J, O’Meara, Megan M., Zhao, Baiteng, Kennedy, Dana A., Erba, Harry P.
Published in Blood (06.12.2014)
Published in Blood (06.12.2014)
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Limiting the Daily Total Nucleated Cell Dose of Cryopreserved Peripheral Blood Stem Cell Products for Autologous Transplantation Improves Infusion-Related Safety with No Adverse Impact on Hematopoietic Engraftment
Khera, Nandita, Jinneman, Jack, Storer, Barry E, Heimfeld, Shelly, O’Meara, Megan M, Chauncey, Thomas R, Lee, Stephanie J, Linenberger, Michael
Published in Biology of blood and marrow transplantation (01.02.2012)
Published in Biology of blood and marrow transplantation (01.02.2012)
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Aberrant methylation of the maspin promoter is an early event in human breast cancer
Futscher, Bernard W, O'Meara, Megan M, Kim, Christina J, Rennels, Margaret A, Lu, Di, Gruman, Lynn M, Seftor, Richard E B, Hendrix, Mary J C, Domann, Frederick E
Published in Neoplasia (New York, N.Y.) (01.07.2004)
Published in Neoplasia (New York, N.Y.) (01.07.2004)
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Journal Article
SGN-CD33A in Combination with Cytarabine or Hypomethylating Agents Demonstrates Enhanced Anti-Leukemic Activity in Preclinical Models of AML
Sutherland, May S.K., Yu, Changpu, Anderson, Martha, Emmerton, Kim, Zeng, Weiping, O’Meara, Megan M., Kennedy, Dana A., Ryan, Maureen C., Benjamin, Dennis R.
Published in Blood (06.12.2014)
Published in Blood (06.12.2014)
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A Phase 1 Study of Two Investigational Agents, ACTR087, an Autologous T Cell Product Expressing an Antibody-Coupled T Cell Receptor, in Combination with SEA-BCMA, a Novel Non-Fucosylated Monoclonal Antibody, in Subjects with Relapsed or Refractory Multiple Myeloma
Benson, Don M., Holmes, Houston, Hari, Parameswaran, Sachs, Jessica, Exter, Ben, Ranger, Ann, Cheema, Tooba, Sienczylo, Iga, O'Meara, Megan M., Sussman, Django, Akard, Luke P.
Published in Blood (29.11.2018)
Published in Blood (29.11.2018)
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Abstract 4642: Model-based alternative clinical trial designs and evaluations for SGN-CD19A, a novel antibody-drug conjugate
Zhao, Baiteng, Albertson, Tina M., Law, Che-Leung, O'Meara, Megan M., Kostic, Ana, Han, Tae H.
Published in Cancer research (Chicago, Ill.) (01.10.2014)
Published in Cancer research (Chicago, Ill.) (01.10.2014)
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Abstract 5551: SGN-2FF: A small-molecule inhibitor of fucosylation modulates immune cell activity in preclinical models and demonstrates pharmacodynamic activity in early phase 1 analysis
Okeley, Nicole M., Heiser, Ryan A., Zeng, Weiping, Hengel, Shawna Mae, Wall, Jason, Haughney, Peter C., Yap, Timothy Anthony, Robert, Francisco, Sanborn, Rachel E., Burris, Howard, Chow, Laura Q., Do, Khanh T., Gutierrez, Martin, Reckamp, Karen, Weise, Amy, Camidge, D Ross, Strickler, John, Steuer, Conor, Wang, Zejing, O'Meara, Megan M., Alley, Stephen C., Gardai, Shyra J.
Published in Cancer research (Chicago, Ill.) (01.07.2018)
Published in Cancer research (Chicago, Ill.) (01.07.2018)
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Journal Article
A Phase 1 Trial of SGN-CD33A As Monotherapy in Patients with CD33-Positive Acute Myeloid Leukemia (AML)
Stein, Anthony S., Walter, Roland B., Erba, Harry P, Fathi, Amir T., Advani, Anjali S., Lancet, Jeffrey E, Ravandi, Farhad, Kovacsovics, Tibor J., DeAngelo, Daniel J., Bixby, Dale, Faderl, Stefan, Jillella, Anand P, O'Meara, Megan M., Zhao, Baiteng, Stein, Eytan M
Published in Blood (03.12.2015)
Published in Blood (03.12.2015)
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Journal Article
SGN-CD33A in Combination with Hypomethylating Agents Is Highly Efficacious in Preclinical Models of AML
Sutherland, May S.K., Yu, Changpu, O'Day, Christine, Alley, Steve, Anderson, Martha, Emmerton, Kim, Zeng, Weipeng, O'Meara, Megan M., Feldman, Eric J., Kennedy, Dana A., Ryan, Maureen C., Benjamin, Dennis
Published in Blood (03.12.2015)
Published in Blood (03.12.2015)
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Journal Article
Vadastuximab Talirine Monotherapy in Older Patients with Treatment Naive CD33-Positive Acute Myeloid Leukemia (AML)
Bixby, Dale L., Stein, Anthony S., Fathi, Amir T., Kovacsovics, Tibor J., Levy, Moshe Y, Erba, Harry P., Lancet, Jeffrey E., Jillella, Anand P, Ravandi, Farhad, Walter, Roland B., Stein, Eytan M., Faderl, Stefan, DeAngelo, Daniel J., Ho, Phoenix, O'Meara, Megan M., Voellinger, Jenna L, Advani, Anjali
Published in Blood (02.12.2016)
Published in Blood (02.12.2016)
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Vadastuximab Talirine Plus Hypomethylating Agents: A Well-Tolerated Regimen with High Remission Rate in Frontline Older Patients with Acute Myeloid Leukemia (AML)
Fathi, Amir T., Erba, Harry P., Lancet, Jeffrey E., Stein, Eytan M., Ravandi, Farhad, Faderl, Stefan, Walter, Roland B., Advani, Anjali, DeAngelo, Daniel J., Kovacsovics, Tibor J., Jillella, Anand P, Bixby, Dale L., Levy, Moshe Y, O'Meara, Megan M., Ho, Phoenix, Stein, Anthony S.
Published in Blood (02.12.2016)
Published in Blood (02.12.2016)
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Journal Article
A Phase 2 Study Of Single-Agent Brentuximab Vedotin For Front-Line Therapy Of Hodgkin Lymphoma In Patients Age 60 Years and Above: Interim Results
Yasenchak, Christopher A., Chen, Robert, Sharman, Jeff P., Boccia, Ralph V., Holkova, Beata, Rosen, Peter J., Friedberg, Jonathan W., O'Meara, Megan M., Forero-Torres, Andres
Published in Blood (15.11.2013)
Published in Blood (15.11.2013)
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