Mechanism of Activation of Protein Kinase JAK2 by the Growth Hormone Receptor
Brooks, Andrew J., Dai, Wei, O'Mara, Megan L., Abankwa, Daniel, Chhabra, Yash, Pelekanos, Rebecca A., Gardon, Olivier, Tunny, Kathryn A., Blucher, Kristopher M., Morton, Craig J., Parker, Michael W., Sierecki, Emma, Gambin, Yann, Gomez, Guillermo A., Alexandrov, Kirill, Wilson, Ian A., Doxastakis, Manolis, Mark, Alan E., Waters, Michael J.
Published in Science (American Association for the Advancement of Science) (16.05.2014)
Published in Science (American Association for the Advancement of Science) (16.05.2014)
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Journal Article
The ryanodine receptor store-sensing gate controls Ca2+ waves and Ca2+-triggered arrhythmias
Chen, Wenqian, Wang, Ruiwu, Chen, Biyi, Zhong, Xiaowei, Kong, Huihui, Bai, Yunlong, Zhou, Qiang, Xie, Cuihong, Zhang, Jingqun, Guo, Ang, Tian, Xixi, Jones, Peter P, O'Mara, Megan L, Liu, Yingjie, Mi, Tao, Zhang, Lin, Bolstad, Jeff, Semeniuk, Lisa, Cheng, Hongqiang, Zhang, Jianlin, Chen, Ju, Tieleman, D Peter, Gillis, Anne M, Duff, Henry J, Fill, Michael, Song, Long-Sheng, Chen, S R Wayne
Published in Nature medicine (01.02.2014)
Published in Nature medicine (01.02.2014)
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Journal Article
High resolution crystal structure of a KRAS promoter G-quadruplex reveals a dimer with extensive poly-A π-stacking interactions for small-molecule recognition
Ou, Arnold, Schmidberger, Jason W, Wilson, Katie A, Evans, Cameron W, Hargreaves, Jessica A, Grigg, Melanie, O'Mara, Megan L, Iyer, K Swaminathan, Bond, Charles S, Smith, Nicole M
Published in Nucleic acids research (04.06.2020)
Published in Nucleic acids research (04.06.2020)
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Journal Article
Synthetically controlling dendrimer flexibility improves delivery of large plasmid DNA
Kretzmann, Jessica A, Ho, Diwei, Evans, Cameron W, Plani-Lam, Janice H C, Garcia-Bloj, Benjamin, Mohamed, A Elaaf, O'Mara, Megan L, Ford, Ethan, Tan, Dennis E K, Lister, Ryan, Blancafort, Pilar, Norret, Marck, Iyer, K Swaminathan
Published in Chemical science (Cambridge) (01.04.2017)
Published in Chemical science (Cambridge) (01.04.2017)
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Journal Article
Imperfect coordination chemistry facilitates metal ion release in the Psa permease
Couñago, Rafael M, Ween, Miranda P, Begg, Stephanie L, Bajaj, Megha, Zuegg, Johannes, O'Mara, Megan L, Cooper, Matthew A, McEwan, Alastair G, Paton, James C, Kobe, Bostjan, McDevitt, Christopher A
Published in Nature chemical biology (01.01.2014)
Published in Nature chemical biology (01.01.2014)
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Journal Article
AdcA and AdcAII employ distinct zinc acquisition mechanisms and contribute additively to zinc homeostasis in Streptococcus pneumoniae
Plumptre, Charles D., Eijkelkamp, Bart A., Morey, Jacqueline R., Behr, Felix, Couñago, Rafael M., Ogunniyi, Abiodun D., Kobe, Bostjan, O'Mara, Megan L., Paton, James C., McDevitt, Christopher A.
Published in Molecular microbiology (01.02.2014)
Published in Molecular microbiology (01.02.2014)
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Journal Article
Location of contact residues in pharmacologically distinct drug binding sites on P-glycoprotein
Mittra, Rituparna, Pavy, Megan, Subramanian, Nanditha, George, Anthony M., O'Mara, Megan L., Kerr, Ian D., Callaghan, Richard
Published in Biochemical pharmacology (01.01.2017)
Published in Biochemical pharmacology (01.01.2017)
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Hydrogen bond‐Driven Self–Assembly between Amidinium Cations and Carboxylate Anions: A Combined Molecular Dynamics, NMR Spectroscopy, and Single Crystal X‐ray Diffraction Study
Thomas, Michael, Anglim Lagones, Thomas, Judd, Martyna, Morshedi, Mahbod, O'Mara, Megan L., White, Nicholas G.
Published in Chemistry, an Asian journal (04.07.2017)
Published in Chemistry, an Asian journal (04.07.2017)
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Journal Article
Hydrophobic Shielding Drives Catalysis of Hydride Transfer in a Family of F420H2‑Dependent Enzymes
Mohamed, A. Elaaf, Condic-Jurkic, Karmen, Ahmed, F. Hafna, Yuan, Peng, O’Mara, Megan L, Jackson, Colin J, Coote, Michelle L
Published in Biochemistry (Easton) (13.12.2016)
Published in Biochemistry (Easton) (13.12.2016)
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Journal Article
Conserved FimH mutations in the global Escherichia coli ST131 multi-drug resistant lineage weaken interdomain interactions and alter adhesin function
Qin, Jilong, Wilson, Katie A., Sarkar, Sohinee, Heras, Begoña, O'Mara, Megan L., Totsika, Makrina
Published in Computational and structural biotechnology journal (01.01.2022)
Published in Computational and structural biotechnology journal (01.01.2022)
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Investigating the lipid fingerprint of SLC6 neurotransmitter transporters: a comparison of dDAT, hDAT, hSERT, and GlyT2
Wilson, Katie A., Wang, Lily, Lin, Yie Chang, O'Mara, Megan L.
Published in BBA advances (01.01.2021)
Published in BBA advances (01.01.2021)
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Journal Article
Structural arrangement of the transmission interface in the antigen ABC transport complex TAP
Oancea, Giani, O'Mara, Megan L, Bennett, W.F. Drew, Tieleman, D. Peter, Abele, Rupert, Tampé, Robert
Published in Proceedings of the National Academy of Sciences - PNAS (07.04.2009)
Published in Proceedings of the National Academy of Sciences - PNAS (07.04.2009)
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