The TREM2-APOE Pathway Drives the Transcriptional Phenotype of Dysfunctional Microglia in Neurodegenerative Diseases
Krasemann, Susanne, Madore, Charlotte, Cialic, Ron, Baufeld, Caroline, Calcagno, Narghes, El Fatimy, Rachid, Beckers, Lien, O’Loughlin, Elaine, Xu, Yang, Fanek, Zain, Greco, David J., Smith, Scott T., Tweet, George, Humulock, Zachary, Zrzavy, Tobias, Conde-Sanroman, Patricia, Gacias, Mar, Weng, Zhiping, Chen, Hao, Tjon, Emily, Mazaheri, Fargol, Hartmann, Kristin, Madi, Asaf, Ulrich, Jason D., Glatzel, Markus, Worthmann, Anna, Heeren, Joerg, Budnik, Bogdan, Lemere, Cynthia, Ikezu, Tsuneya, Heppner, Frank L., Litvak, Vladimir, Holtzman, David M., Lassmann, Hans, Weiner, Howard L., Ochando, Jordi, Haass, Christian, Butovsky, Oleg
Published in Immunity (Cambridge, Mass.) (19.09.2017)
Published in Immunity (Cambridge, Mass.) (19.09.2017)
Get full text
Journal Article
Microglial Phenotypes and Functions in Multiple Sclerosis
O'Loughlin, Elaine, Madore, Charlotte, Lassmann, Hans, Butovsky, Oleg
Published in Cold Spring Harbor perspectives in medicine (01.02.2018)
Published in Cold Spring Harbor perspectives in medicine (01.02.2018)
Get full text
Journal Article
Acute in utero exposure to lipopolysaccharide induces inflammation in the pre- and postnatal brain and alters the glial cytoarchitecture in the developing amygdala
O'Loughlin, Elaine, Pakan, Janelle M P, Yilmazer-Hanke, Deniz, McDermott, Kieran W
Published in Journal of neuroinflammation (02.11.2017)
Published in Journal of neuroinflammation (02.11.2017)
Get full text
Journal Article
Interdependent and independent roles of type I interferons and IL-6 in innate immune, neuroinflammatory and sickness behaviour responses to systemic poly I:C
Murray, Carol, Griffin, Éadaoin W, O’Loughlin, Elaine, Lyons, Aoife, Sherwin, Eoin, Ahmed, Suaad, Stevenson, Nigel J, Harkin, Andrew, Cunningham, Colm
Published in Brain, behavior, and immunity (01.08.2015)
Published in Brain, behavior, and immunity (01.08.2015)
Get full text
Journal Article
Human Alzheimer's disease gene expression signatures and immune profile in APP mouse models: a discrete transcriptomic view of Aβ plaque pathology
Rothman, Sarah M, Tanis, Keith Q, Gandhi, Pallavi, Malkov, Vladislav, Marcus, Jacob, Pearson, Michelle, Stevens, Richard, Gilliland, Jason, Ware, Christopher, Mahadomrongkul, Veeravan, O'Loughlin, Elaine, Zeballos, Gonzalo, Smith, Roger, Howell, Bonnie J, Klappenbach, Joel, Kennedy, Matthew, Mirescu, Christian
Published in Journal of neuroinflammation (06.09.2018)
Published in Journal of neuroinflammation (06.09.2018)
Get full text
Journal Article
Expression of neuropeptide Y1 receptors in the amygdala and hippocampus and anxiety-like behavior associated with Ammon's horn sclerosis following intrahippocampal kainate injection in C57BL/6J mice
O'Loughlin, Elaine K, Pakan, Janelle M.P, McDermott, Kieran W, Yilmazer-Hanke, Deniz
Published in Epilepsy & behavior (01.08.2014)
Published in Epilepsy & behavior (01.08.2014)
Get full text
Journal Article
Differential contribution of microglia and monocytes in neurodegenerative diseases
Baufeld, Caroline, O’Loughlin, Elaine, Calcagno, Narghes, Madore, Charlotte, Butovsky, Oleg
Published in Journal of Neural Transmission (01.05.2018)
Published in Journal of Neural Transmission (01.05.2018)
Get full text
Journal Article
Human Alzheimer's disease gene expression signatures and immune profile in APP mouse models: a discrete transcriptomic view of A[beta] plaque pathology
Rothman, Sarah M, Tanis, Keith Q, Gandhi, Pallavi, Malkov, Vladislav, Marcus, Jacob, Pearson, Michelle, Stevens, Richard, Gilliland, Jason, Ware, Christopher, Mahadomrongkul, Veeravan, O'Loughlin, Elaine, Zeballos, Gonzalo, Smith, Roger, Howell, Bonnie J, Klappenbach, Joel, Kennedy, Matthew, Mirescu, Christian
Published in Journal of neuroinflammation (06.09.2018)
Published in Journal of neuroinflammation (06.09.2018)
Get full text
Journal Article
C57BL6 mouse substrains demonstrate differences in susceptibility to the demyelinating effects of Cuprizone toxin
Elaine O’loughlin, Jacob, Binod, Zeballos, Gonzalo, Manfre, Philip, Mccullough, Anjali, Gatto, Nicholas Thomas, Tsuchiya, Takayuki, Anna-Mari Karkkainen, Lehtimäki, Kimmo, Kuosmanen, Juha, Rosahl, Thomas W, Varty, Geoffrey B, Kennedy, Matthew E, Mirescu, Christian, Bardehle, Sophia
Published in bioRxiv (18.12.2020)
Published in bioRxiv (18.12.2020)
Get full text
Paper