MYBPC3 truncation mutations enhance actomyosin contractile mechanics in human hypertrophic cardiomyopathy
O'Leary, Thomas S., Snyder, Julia, Sadayappan, Sakthivel, Day, Sharlene M., Previs, Michael J.
Published in Journal of molecular and cellular cardiology (01.02.2019)
Published in Journal of molecular and cellular cardiology (01.02.2019)
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Journal Article
Physiologic biomechanics enhance reproducible contractile development in a stem cell derived cardiac muscle platform
Tsan, Yao-Chang, DePalma, Samuel J., Zhao, Yan-Ting, Capilnasiu, Adela, Wu, Yu-Wei, Elder, Brynn, Panse, Isabella, Ufford, Kathryn, Matera, Daniel L., Friedline, Sabrina, O’Leary, Thomas S., Wubshet, Nadab, Ho, Kenneth K. Y., Previs, Michael J., Nordsletten, David, Isom, Lori L., Baker, Brendon M., Liu, Allen P., Helms, Adam S.
Published in Nature communications (25.10.2021)
Published in Nature communications (25.10.2021)
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Journal Article
The N terminus of myosin-binding protein C extends toward actin filaments in intact cardiac muscle
Rahmanseresht, Sheema, Lee, Kyoung H, O'Leary, Thomas S, McNamara, James W, Sadayappan, Sakthivel, Robbins, Jeffrey, Warshaw, David M, Craig, Roger, Previs, Michael J
Published in The Journal of general physiology (01.03.2021)
Published in The Journal of general physiology (01.03.2021)
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Journal Article
Myosin-binding protein H-like regulates myosin-binding protein distribution and function in atrial cardiomyocytes
Barefield, David Y, Tonino, Paola, Woulfe, Kathleen C, Rahmanseresht, Sheema, O'Leary, Thomas S, Burnham, Hope V, Wasserstrom, J Andrew, Kirk, Jonathan A, Previs, Michael J, Granzier, Henk L, McNally, Elizabeth M
Published in Proceedings of the National Academy of Sciences - PNAS (19.12.2023)
Published in Proceedings of the National Academy of Sciences - PNAS (19.12.2023)
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Journal Article
Defects in the Proteome and Metabolome in Human Hypertrophic Cardiomyopathy
Previs, Michael J., O’Leary, Thomas S., Morley, Michael P., Palmer, Bradley M., LeWinter, Martin, Yob, Jaime M., Pagani, Francis D., Petucci, Christopher, Kim, Min-Soo, Margulies, Kenneth B., Arany, Zoltan, Kelly, Daniel P., Day, Sharlene M.
Published in Circulation. Heart failure (01.06.2022)
Published in Circulation. Heart failure (01.06.2022)
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Journal Article
Skeletal MyBP-C isoforms tune the molecular contractility of divergent skeletal muscle systems
Li, Amy, Nelson, Shane R., Rahmanseresht, Sheema, Braet, Filip, Cornachione, Anabelle S., Previs, Samantha Beck, O’Leary, Thomas S., McNamara, James W., Rassier, Dilson E., Sadayappan, Sakthivel, Previs, Michael J., Warshaw, David M.
Published in Proceedings of the National Academy of Sciences - PNAS (22.10.2019)
Published in Proceedings of the National Academy of Sciences - PNAS (22.10.2019)
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Journal Article
Effects of MYBPC3 loss-of-function mutations preceding hypertrophic cardiomyopathy
Helms, Adam S, Tang, Vi T, O'Leary, Thomas S, Friedline, Sabrina, Wauchope, Mick, Arora, Akul, Wasserman, Aaron H, Smith, Eric D, Lee, Lap Man, Wen, Xiaoquan W, Shavit, Jordan A, Liu, Allen P, Previs, Michael J, Day, Sharlene M
Published in JCI insight (30.01.2020)
Published in JCI insight (30.01.2020)
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Journal Article
Integrating GWAS and Transcriptomics to Identify the Molecular Underpinnings of Thermal Stress Responses in Drosophila melanogaster
Lecheta, Melise C, Awde, David N, O'Leary, Thomas S, Unfried, Laura N, Jacobs, Nicholas A, Whitlock, Miles H, McCabe, Eleanor, Powers, Beck, Bora, Katie, Waters, James S, Axen, Heather J, Frietze, Seth, Lockwood, Brent L, Teets, Nicholas M, Cahan, Sara H
Published in Frontiers in genetics (23.06.2020)
Published in Frontiers in genetics (23.06.2020)
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Journal Article
Cardiac Myosin Filaments are Maintained by Stochastic Protein Replacement
Wood, Neil B., Kelly, Colleen M., O’Leary, Thomas S., Martin, Jody L., Previs, Michael J.
Published in Molecular & cellular proteomics (01.10.2022)
Published in Molecular & cellular proteomics (01.10.2022)
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Journal Article
Replacement of Myosin Molecules within Cardiac Thick Filaments in Intact Mouse Hearts
Previs, Michael J., Martin, Jody L., Spees, Jeffrey L., O'Leary, Thomas S.
Published in Biophysical journal (07.02.2020)
Published in Biophysical journal (07.02.2020)
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Journal Article
Defects in the Proteome and Metabolome in Human Hypertrophic Cardiomyopathy
Previs, Michael J., O’Leary, Thomas S., Morley, Michael P., Palmer, Bradley M., LeWinter, Martin, Yob, Jaime M., Pagani, Francis D., Petucci, Christopher, Kim, Min-Soo, Margulies, Kenneth B., Arany, Zoltan, Kelly, Daniel P., Day, Sharlene M.
Published in Circulation. Heart failure (11.05.2022)
Published in Circulation. Heart failure (11.05.2022)
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Journal Article
SKELETAL MyBP-C ISOFORMS TUNE THE MOLECULAR CONTRACTILITY OF DIVERGENT SKELETAL MUSCLE SYSTEMS
Li, Amy, Nelson, Shane, Rahmanseresht, Sheema, Braet, Filip, Cornachione, Anabelle S, Samantha Beck Previs, O'leary, Thomas S, Mcnamara, James W, Rassier, Dilson E, Sakthivel Sadayappan, Previs, Michael J, Warshaw, David M
Published in bioRxiv (21.06.2019)
Published in bioRxiv (21.06.2019)
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