Prophylactic administration of avotermin for improvement of skin scarring: three double-blind, placebo-controlled, phase I/II studies
Ferguson, Mark WJ, Prof, Duncan, Jonathan, MD, Bond, Jeremy, MB, Bush, James, MB, Durani, Piyush, MD, So, Karen, MB, Taylor, Lisa, MB, Chantrey, Jonquille, MB, Mason, Tracey, PhD, James, Gaynor, MSc, Laverty, Hugh, PhD, Occleston, Nick L, PhD, Sattar, Abdul, PhD, Ludlow, Anna, PhD, O'Kane, Sharon, PhD
Published in The Lancet (British edition) (11.04.2009)
Published in The Lancet (British edition) (11.04.2009)
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Interleukin-10 reduces scar formation in both animal and human cutaneous wounds: Results of two preclinical and phase II randomized control studies
Kieran, Ingrid, Knock, Amanda, Bush, James, So, Karen, Metcalfe, Anthony, Hobson, Rosalind, Mason, Tracey, O'Kane, Sharon, Ferguson, Mark
Published in Wound repair and regeneration (01.05.2013)
Published in Wound repair and regeneration (01.05.2013)
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Discovery and development of avotermin (recombinant human transforming growth factor beta 3): A new class of prophylactic therapeutic for the improvement of scarring
Occleston, Nick L., O'Kane, Sharon, Laverty, Hugh G., Cooper, Mark, Fairlamb, David, Mason, Tracey, Bush, Jim A., Ferguson, Mark W.J.
Published in Wound repair and regeneration (01.09.2011)
Published in Wound repair and regeneration (01.09.2011)
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Journal Article
Prevention and reduction of scarring in the skin by Transforming Growth Factor beta 3 (TGFβ3): from laboratory discovery to clinical pharmaceutical
Occleston, Nick L., Laverty, Hugh G., O'Kane, Sharon, Ferguson, Mark W. J.
Published in Journal of biomaterials science. Polymer ed. (01.01.2008)
Published in Journal of biomaterials science. Polymer ed. (01.01.2008)
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Avotermin for scar improvement following scar revision surgery: a randomized, double-blind, within-patient, placebo-controlled, phase II clinical trial
So, Karen, McGrouther, Duncan A, Bush, James A, Durani, Piyush, Taylor, Lisa, Skotny, Gaynor, Mason, Tracey, Metcalfe, Anthony, O'Kane, Sharon, Ferguson, Mark W J
Published in Plastic and reconstructive surgery (1963) (01.07.2011)
Published in Plastic and reconstructive surgery (1963) (01.07.2011)
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The microcirculation in acute murine cutaneous incisional wounds shows a spatial and temporal variation in the functionality of vessels
Bluff, Joanne E., O'Ceallaigh, Siobhan, O'Kane, Sharon, Ferguson, Mark W. J., Ireland, Grenham
Published in Wound repair and regeneration (01.07.2006)
Published in Wound repair and regeneration (01.07.2006)
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Therapeutic Improvement of Scarring: Mechanisms of Scarless and Scar-Forming Healing and Approaches to the Discovery of New Treatments
Occleston, Nick L., Metcalfe, Anthony D., Boanas, Adam, Burgoyne, Nicholas J., Nield, Kerry, O'Kane, Sharon, Ferguson, Mark W. J.
Published in Dermatology Research and Practice (01.01.2010)
Published in Dermatology Research and Practice (01.01.2010)
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Journal Article
Severely Impaired Wound Healing in the Collagenase-Resistant Mouse
Beare, Alice H.M., O'Kane, Sharon, Ferguson, Mark W.J., Krane, Stephen M.
Published in Journal of investigative dermatology (01.01.2003)
Published in Journal of investigative dermatology (01.01.2003)
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Journal Article
Transforming growth factor-β levels during second- intention healing are related to the different course of wound contraction in horses and ponies
Van Den Boom, Robin, Wilmink, Jacintha M., O'Kane, Sharon, Wood, Jason, Ferguson, Mark W. J.
Published in Wound repair and regeneration (01.05.2002)
Published in Wound repair and regeneration (01.05.2002)
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Journal Article
Therapies with Emerging Evidence of Efficacy: Avotermin for the Improvement of Scarring
Bush, Jim, So, Karen, Mason, Tracey, Occleston, Nick L., O′Kane, Sharon, Ferguson, Mark W. J.
Published in Dermatology Research and Practice (01.01.2010)
Published in Dermatology Research and Practice (01.01.2010)
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Maturation of the human scar: an observational study
Bond, Jeremy S, Duncan, Jonathan A L, Sattar, Abdul, Boanas, Adam, Mason, Tracey, O'Kane, Sharon, Ferguson, Mark W J
Published in Plastic and reconstructive surgery (1963) (01.05.2008)
Published in Plastic and reconstructive surgery (1963) (01.05.2008)
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New therapeutics for the prevention and reduction of scarring
Occleston, Nick L., O’Kane, Sharon, Goldspink, Nick, Ferguson, Mark W.J.
Published in Drug discovery today (01.11.2008)
Published in Drug discovery today (01.11.2008)
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Journal Article
Scar-improving efficacy of avotermin administered into the wound margins of skin incisions as evaluated by a randomized, double-blind, placebo-controlled, phase II clinical trial
Bush, James, Duncan, Jonathan A L, Bond, Jeremy S, Durani, Piyush, So, Karen, Mason, Tracey, O'Kane, Sharon, Ferguson, Mark W J
Published in Plastic and reconstructive surgery (1963) (01.11.2010)
Published in Plastic and reconstructive surgery (1963) (01.11.2010)
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A synthetic gene increases TGFβ3 accumulation by 75-fold in tobacco chloroplasts enabling rapid purification and folding into a biologically active molecule
Gisby, Martin F., Mellors, Philip, Madesis, Panagiotis, Ellin, Marianne, Laverty, Hugh, O'Kane, Sharon, Ferguson, Mark W. J., Day, Anil
Published in Plant biotechnology journal (01.06.2011)
Published in Plant biotechnology journal (01.06.2011)
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Journal Article
Scarring impedes regeneration at sites of peripheral nerve repair
Atkins, Simon, Smith, Keith G, Loescher, Alison R, Boissonade, Fiona M, O'Kane, Sharon, Ferguson, Mark W J, Robinson, Peter P
Published in Neuroreport (21.08.2006)
Published in Neuroreport (21.08.2006)
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Journal Article
Interleukin-10 reduces scarring and enhances regeneration at a site of sciatic nerve repair
Atkins, Simon, Loescher, Alison R., Boissonade, Fiona M., Smith, Keith G., Occleston, Nick, O'Kane, Sharon, Ferguson, Mark W. J., Robinson, Peter P.
Published in Journal of the peripheral nervous system (01.12.2007)
Published in Journal of the peripheral nervous system (01.12.2007)
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Journal Article
Scar redness in humans: how long does it persist after incisional and excisional wounding?
Bond, Jeremy S, Duncan, Jonathan A L, Mason, Tracey, Sattar, Abdul, Boanas, Adam, O'Kane, Sharon, Ferguson, Mark W J
Published in Plastic and reconstructive surgery (1963) (01.02.2008)
Published in Plastic and reconstructive surgery (1963) (01.02.2008)
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