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Published in Nature chemical biology (01.08.2015)
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Published in iScience (26.10.2018)
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Donated chemical probes for open science
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Components of the Rb Pathway Are Critical Targets of UV Mutagenesis in a Murine Melanoma Model
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Published in Proceedings of the National Academy of Sciences - PNAS (04.02.2003)
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Published in iScience (31.05.2019)
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Published in Nature communications (17.12.2019)
Published in Nature communications (17.12.2019)
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XTX101, a tumor-activated, Fc-enhanced anti-CTLA-4 monoclonal antibody, demonstrates tumor-growth inhibition and tumor-selective pharmacodynamics in mouse models of cancer
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HER2/Neu and the Ets transcription activator PEA3 are coordinately upregulated in human breast cancer
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Published in Oncogene (25.09.1997)
Published in Oncogene (25.09.1997)
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Treatment with the PARP inhibitor, niraparib, sensitizes colorectal cancer cell lines to irinotecan regardless of MSI/MSS status
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Published in Cancer cell international (04.02.2015)
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Analysis of C-MYC Function in Normal Cells via Conditional Gene-Targeted Mutation
de Alboran, Ignacio Moreno, O'Hagan, Rónán C, Gärtner, Frank, Malynn, Barbara, Davidson, Laurie, Rickert, Robert, Rajewsky, Klaus, DePinho, Ronald A, Alt, Frederick W
Published in Immunity (Cambridge, Mass.) (2001)
Published in Immunity (Cambridge, Mass.) (2001)
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Genetic Analysis of Pten and Ink4a/Arf Interactions in the Suppression of Tumorigenesis in Mice
You, Mingjian James, Castrillon, Diego H., Bastian, Boris C., O'Hagan, Rónán C., Bosenberg, Marcus W., Parsons, Ramon, Chin, Lynda, DePinho, Ronald A.
Published in Proceedings of the National Academy of Sciences - PNAS (05.02.2002)
Published in Proceedings of the National Academy of Sciences - PNAS (05.02.2002)
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Tumor-selective activity of XTX202, a protein-engineered IL-2, in mice without peripheral toxicities in nonhuman primates
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Published in Journal of clinical oncology (20.05.2021)
Published in Journal of clinical oncology (20.05.2021)
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587 Tumor-activated Fc-engineered anti-CTLA-4 monoclonal antibody, XTX101, demonstrates tumor-selective PD and efficacy in preclinical models
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Published in Journal for immunotherapy of cancer (01.11.2020)
Published in Journal for immunotherapy of cancer (01.11.2020)
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568 XTX201, a protein-engineered IL-2, exhibits tumor-selective activity in mice without peripheral toxicities in non-human primates
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Published in Journal for immunotherapy of cancer (01.11.2020)
Published in Journal for immunotherapy of cancer (01.11.2020)
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Telomerase reverse transcriptase gene is a direct target of c-Myc but is not functionally equivalent in cellular transformation
GREENBERG, R. A, O'HAGAN, R. C, HONGYU DENG, QIURONG XIAO, HANN, S. R, ADAMS, R. R, LICHTSTEINER, S, CHIN, L, MORIN, G. B, DEPINHO, R. A
Published in Oncogene (04.02.1999)
Published in Oncogene (04.02.1999)
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Gene-target recognition among members of the Myc superfamily and implications for oncogenesis
DePinho, Ronald A, O'Hagan, Rónán C, Schreiber-Agus, Nicole, Chen, Ken, David, Gregory, Engelman, Jeffrey A, Schwab, Richard, Alland, Leila, Thomson, Cole, Ronning, Donald R, Sacchettini, James C, Meltzer, Paul
Published in Nature genetics (01.02.2000)
Published in Nature genetics (01.02.2000)
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