The anti-obesity effect of FGF19 does not require UCP1-dependent thermogenesis
Antonellis, Patrick J., Droz, Brian A., Cosgrove, Richard, O'Farrell, Libbey S., Coskun, Tamer, Perfield, James W., Bauer, Steven, Wade, Mark, Chouinard, Tara E., Brozinick, Joseph T., Adams, Andrew C., Samms, Ricardo J.
Published in Molecular metabolism (Germany) (01.12.2019)
Published in Molecular metabolism (Germany) (01.12.2019)
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Journal Article
LY3437943, a novel triple glucagon, GIP, and GLP-1 receptor agonist for glycemic control and weight loss: From discovery to clinical proof of concept
Coskun, Tamer, Urva, Shweta, Roell, William C., Qu, Hongchang, Loghin, Corina, Moyers, Julie S., O’Farrell, Libbey S., Briere, Daniel A., Sloop, Kyle W., Thomas, Melissa K., Pirro, Valentina, Wainscott, David B., Willard, Francis S., Abernathy, Matthew, Morford, LaRonda, Du, Yu, Benson, Charles, Gimeno, Ruth E., Haupt, Axel, Milicevic, Zvonko
Published in Cell metabolism (06.09.2022)
Published in Cell metabolism (06.09.2022)
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Journal Article
Secretin-Activated Brown Fat Mediates Prandial Thermogenesis to Induce Satiation
Li, Yongguo, Schnabl, Katharina, Gabler, Sarah-Madeleine, Willershäuser, Monja, Reber, Josefine, Karlas, Angelos, Laurila, Sanna, Lahesmaa, Minna, u Din, Mueez, Bast-Habersbrunner, Andrea, Virtanen, Kirsi A., Fromme, Tobias, Bolze, Florian, O’Farrell, Libbey S., Alsina-Fernandez, Jorge, Coskun, Tamer, Ntziachristos, Vasilis, Nuutila, Pirjo, Klingenspor, Martin
Published in Cell (29.11.2018)
Published in Cell (29.11.2018)
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Journal Article
GIPR Agonism Enhances TZD-Induced Insulin Sensitivity in Obese IR Mice
Furber, Ellen C, Hyatt, Karissa, Collins, Kyla, Yu, Xinxin, Droz, Brian A, Holland, Adrienne, Friedrich, Jessica L, Wojnicki, Samantha, Konkol, Debra L, O'Farrell, Libbey S, Baker, Hana E, Coskun, Tamer, Scherer, Philipp E, Kusminski, Christine M, Christe, Michael E, Sloop, Kyle W, Samms, Ricardo J
Published in Diabetes (New York, N.Y.) (01.02.2024)
Published in Diabetes (New York, N.Y.) (01.02.2024)
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Journal Article
Tirzepatide modulates the regulation of adipocyte nutrient metabolism through long-acting activation of the GIP receptor
Regmi, Ajit, Aihara, Eitaro, Christe, Michael E., Varga, Gabor, Beyer, Thomas P., Ruan, Xiaoping, Beebe, Emily, O’Farrell, Libbey S., Bellinger, Melissa A., Austin, Aaron K., Lin, Yanzhu, Hu, Haitao, Konkol, Debra L., Wojnicki, Samantha, Holland, Adrienne K., Friedrich, Jessica L., Brown, Robert A., Estelle, Amanda S., Badger, Hannah S., Gaidosh, Gabriel S., Kooijman, Sander, Rensen, Patrick C.N., Coskun, Tamer, Thomas, Melissa K., Roell, William
Published in Cell metabolism (02.07.2024)
Published in Cell metabolism (02.07.2024)
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Journal Article
Tirzepatide modulates the regulation of adipocyte nutrient metabolism through long-acting activation of the GIP receptor
Regmi, Ajit, Aihara, Eitaro, Christe, Michael E., Varga, Gabor, Beyer, Thomas P., Ruan, Xiaoping, Beebe, Emily, O’Farrell, Libbey S., Bellinger, Melissa A., Austin, Aaron K., Lin, Yanzhu, Hu, Haitao, Konkol, Debra L., Wojnicki, Samantha, Holland, Adrienne K., Friedrich, Jessica L., Brown, Robert A., Estelle, Amanda S., Badger, Hannah S., Gaidosh, Gabriel S., Kooijman, Sander, Rensen, Patrick C.N., Coskun, Tamer, Thomas, Melissa K., Roell, William
Published in Cell metabolism (06.08.2024)
Published in Cell metabolism (06.08.2024)
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Journal Article
GIPR agonism mediates weight-independent insulin sensitization by tirzepatide in obese mice
Samms, Ricardo J, Christe, Michael E, Collins, Kyla A, Pirro, Valentina, Droz, Brian A, Holland, Adrienne K, Friedrich, Jessica L, Wojnicki, Samantha, Konkol, Debra L, Cosgrove, Richard, Conceição Furber, Ellen Ps, Ruan, Xiaoping, O'Farrell, Libbey S, Long, Annie M, Dogra, Mridula, Willency, Jill A, Lin, Yanzhu, Ding, Liyun, Cheng, Christine C, Cabrera, Over, Briere, Daniel A, Alsina-Fernandez, Jorge, Gimeno, Ruth E, Moyers, Julie S, Coskun, Tamer, Coghlan, Matthew P, Sloop, Kyle W, Roell, William C
Published in The Journal of clinical investigation (15.06.2021)
Published in The Journal of clinical investigation (15.06.2021)
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Journal Article
Activation of Prostaglandin E Receptor 4 Triggers Secretion of Gut Hormone Peptides GLP-1, GLP-2, and PYY
Coskun, Tamer, O'Farrell, Libbey S, Syed, Samreen K, Briere, Daniel A, Beavers, Lisa S, DuBois, Susan L, Michael, Mervyn D, Franciskovich, Jeffry B, Barrett, David G, Efanov, Alexander M
Published in Endocrinology (Philadelphia) (01.01.2013)
Published in Endocrinology (Philadelphia) (01.01.2013)
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Combination of a Beta Adrenoceptor Modulator and a Norepinephrine-Serotonin Uptake Inhibitor for the Treatment of Obesity
Jesudason, Cynthia D., Baker, James E., Bryant, Robert D., Fisher, Jack W., O’Farrell, Libbey S., Gaich, Gregory A., He, Minxia M., Kahl, Steven D., Kriauciunas, Aidas V., Heiman, Mark L., Peters, Mary A., Rito, Christopher J., Satterwhite, Julie H., Tinsley, Frank C., Trankle, William G., Shuker, Anthony J.
Published in ACS medicinal chemistry letters (11.08.2011)
Published in ACS medicinal chemistry letters (11.08.2011)
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Journal Article
Fibroblast growth factor 21 is not required for the antidiabetic actions of the thiazoladinediones
Adams, Andrew C., PhD, Coskun, Tamer, MD, Cheng, Christine C, O′Farrell, Libbey S, DuBois, Susan L, Kharitonenkov, Alexei, PhD
Published in Molecular metabolism (Germany) (01.08.2013)
Published in Molecular metabolism (Germany) (01.08.2013)
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