Staphylococcus aureus membrane vesicles contain immunostimulatory DNA, RNA and peptidoglycan that activate innate immune receptors and induce autophagy
Bitto, Natalie J., Cheng, Lesley, Johnston, Ella L., Pathirana, Rishi, Phan, Thanh Kha, Poon, Ivan K. H., O'Brien‐Simpson, Neil M., Hill, Andrew F., Stinear, Timothy P., Kaparakis‐Liaskos, Maria
Published in Journal of extracellular vesicles (01.04.2021)
Published in Journal of extracellular vesicles (01.04.2021)
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Recent Applications of Aggregation Induced Emission Probes for Antimicrobial Peptide Studies
Luu, Tracey, Li, Wenyi, O'Brien‐Simpson, Neil M., Hong, Yuning
Published in Chemistry, an Asian journal (03.05.2021)
Published in Chemistry, an Asian journal (03.05.2021)
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Enhanced Antibacterial Activity of Se Nanoparticles Upon Coating with Recombinant Spider Silk Protein eADF4(κ16)
Huang, Tao, Kumari, Sushma, Herold, Heike, Bargel, Hendrik, Aigner, Tamara B, Heath, Daniel E, O'Brien-Simpson, Neil M, O'Connor, Andrea J, Scheibel, Thomas
Published in International journal of nanomedicine (01.01.2020)
Published in International journal of nanomedicine (01.01.2020)
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Effect of a protease‐activated receptor‐2 antagonist (GB88) on inflammation‐related loss of alveolar bone in periodontal disease
Francis, Nidhish, Sanaei, Reza, Ayodele, Babatunde A., O'Brien‐Simpson, Neil M., Fairlie, David P., Wijeyewickrema, Lakshmi C., Pike, Robert N., Mackie, Eleanor Jean, Pagel, Charles Neil
Published in Journal of periodontal research (01.06.2023)
Published in Journal of periodontal research (01.06.2023)
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Chemically modified and conjugated antimicrobial peptides against superbugs
Li, Wenyi, Separovic, Frances, O'Brien-Simpson, Neil M, Wade, John D
Published in Chemical Society reviews (26.04.2021)
Published in Chemical Society reviews (26.04.2021)
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Architectural Effects of Star-Shaped "Structurally Nanoengineered Antimicrobial Peptide Polymers" (SNAPPs) on Their Biological Activity
Shirbin, Steven J, Insua, Ignacio, Holden, James A, Lenzo, Jason C, Reynolds, Eric C, O'Brien-Simpson, Neil M, Qiao, Greg G
Published in Advanced healthcare materials (01.11.2018)
Published in Advanced healthcare materials (01.11.2018)
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Keratinocyte‐specific ablation of protease‐activated receptor 2 prevents gingival inflammation and bone loss in a mouse model of periodontal disease
Francis, Nidhish, Ayodele, Babatunde A., O'Brien‐Simpson, Neil M., Birchmeier, Walter, Pike, Robert N., Pagel, Charles N., Mackie, Eleanor J.
Published in Cellular microbiology (01.11.2018)
Published in Cellular microbiology (01.11.2018)
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The overview of antimicrobial peptide‐coated implants against oral bacterial infections
Sun, Zhe, Ma, Li, Sun, Xiaodong, Sloan, Alastair J., O'Brien‐Simpson, Neil M., Li, Wenyi
Published in Aggregate (Hoboken) (01.06.2023)
Published in Aggregate (Hoboken) (01.06.2023)
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Celogentin mimetics as inhibitors of tubulin polymerization
Thombare, Varsha J., Holden, James A., Reynolds, Eric C., O'Brien‐Simpson, Neil M., Hutton, Craig A.
Published in Journal of peptide science (01.03.2020)
Published in Journal of peptide science (01.03.2020)
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Adolescent temperament dimensions as stable prospective risk and protective factors for salivary C‐reactive protein
Nelson, Benjamin W., Byrne, Michelle L., Simmons, Julian G., Whittle, Sarah, Schwartz, Orli S., O'Brien‐Simpson, Neil M., Walsh, Katrina A., Reynolds, Eric C., Allen, Nicholas B.
Published in British journal of health psychology (01.02.2018)
Published in British journal of health psychology (01.02.2018)
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Engineering highly effective antimicrobial selenium nanoparticles through control of particle size
Huang, Tao, Holden, James A, Heath, Daniel E, O'Brien-Simpson, Neil M, O'Connor, Andrea J
Published in Nanoscale (08.08.2019)
Published in Nanoscale (08.08.2019)
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GM‐CSF and uPA are required for Porphyromonas gingivalis‐induced alveolar bone loss in a mouse periodontitis model
Lam, Roselind S, O'Brien‐Simpson, Neil M, Hamilton, John A, Lenzo, Jason C, Holden, James A, Brammar, Gail C, Orth, Rebecca K, Tan, Yan, Walsh, Katrina A, Fleetwood, Andrew J, Reynolds, Eric C
Published in Immunology and cell biology (01.09.2015)
Published in Immunology and cell biology (01.09.2015)
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Chronic oral application of a periodontal pathogen results in brain inflammation, neurodegeneration and amyloid beta production in wild type mice
Ilievski, Vladimir, Zuchowska, Paulina K, Green, Stefan J, Toth, Peter T, Ragozzino, Michael E, Le, Khuong, Aljewari, Haider W, O'Brien-Simpson, Neil M, Reynolds, Eric C, Watanabe, Keiko
Published in PloS one (03.10.2018)
Published in PloS one (03.10.2018)
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Systematic comparison of activity and mechanism of antimicrobial peptides against nosocomial pathogens
Lin, Bruce, Hung, Andrew, Li, Rong, Barlow, Anders, Singleton, William, Matthyssen, Tamara, Sani, Marc-Antoine, Hossain, Mohammed Akhter, Wade, John D., O'Brien-Simpson, Neil M., Li, Wenyi
Published in European journal of medicinal chemistry (05.03.2022)
Published in European journal of medicinal chemistry (05.03.2022)
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Ring opening polymerization of α-amino acids: advances in synthesis, architecture and applications of polypeptides and their hybrids
Rasines Mazo, Alicia, Allison-Logan, Stephanie, Karimi, Fatemeh, Chan, Nicholas Jun-An, Qiu, Wenlian, Duan, Wei, O'Brien-Simpson, Neil M, Qiao, Greg G
Published in Chemical Society reviews (21.07.2020)
Published in Chemical Society reviews (21.07.2020)
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A therapeutic Porphyromonas gingivalis gingipain vaccine induces neutralising IgG1 antibodies that protect against experimental periodontitis
O'Brien-Simpson, Neil M, Holden, James A, Lenzo, Jason C, Tan, Yan, Brammar, Gail C, Walsh, Katrina A, Singleton, William, Orth, Rebecca K H, Slakeski, Nada, Cross, Keith J, Darby, Ivan B, Becher, Dorit, Rowe, Tony, Morelli, Adriana Baz, Hammet, Andrew, Nash, Andrew, Brown, Anna, Ma, Bing, Vingadassalom, Didier, McCluskey, Jacqueline, Kleanthous, Harold, Reynolds, Eric C
Published in npj vaccines (01.12.2016)
Published in npj vaccines (01.12.2016)
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Metabolic Remodeling, Inflammasome Activation, and Pyroptosis in Macrophages Stimulated by Porphyromonas gingivalis and Its Outer Membrane Vesicles
Fleetwood, Andrew J, Lee, Man K S, Singleton, William, Achuthan, Adrian, Lee, Ming-Chin, O'Brien-Simpson, Neil M, Cook, Andrew D, Murphy, Andrew J, Dashper, Stuart G, Reynolds, Eric C, Hamilton, John A
Published in Frontiers in cellular and infection microbiology (04.08.2017)
Published in Frontiers in cellular and infection microbiology (04.08.2017)
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Porphyromonas gingivalis lipopolysaccharide weakly activates M1 and M2 polarized mouse macrophages but induces inflammatory cytokines
Holden, James A, Attard, Troy J, Laughton, Katrina M, Mansell, Ashley, O'Brien-Simpson, Neil M, Reynolds, Eric C
Published in Infection and immunity (01.10.2014)
Published in Infection and immunity (01.10.2014)
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