A Comparison of Methods for Modeling Quantitative Structure−Activity Relationships
Sutherland, Jeffrey J, O'Brien, Lee A, Weaver, Donald F
Published in Journal of medicinal chemistry (21.10.2004)
Published in Journal of medicinal chemistry (21.10.2004)
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Journal Article
Treatment of Sepsis-Induced Acquired Protein C Deficiency Reverses Angiotensin-Converting Enzyme-2 Inhibition and Decreases Pulmonary Inflammatory Response
Richardson, Mark A, Gupta, Akanksha, O'Brien, Lee A, Berg, David T, Gerlitz, Bruce, Syed, Samreen, Sharma, Ganesh R, Cramer, Martin S, Heuer, Josef G, Galbreath, Elizabeth J, Grinnell, Brian W
Published in The Journal of pharmacology and experimental therapeutics (01.04.2008)
Published in The Journal of pharmacology and experimental therapeutics (01.04.2008)
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Journal Article
Activated protein C and sepsis
O'Brien, Lee A, Gupta, Akanksha, Grinnell, Brian W
Published in Frontiers in bioscience (01.01.2006)
Published in Frontiers in bioscience (01.01.2006)
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Journal Article
Negative Regulation of Inducible Nitric-oxide Synthase Expression Mediated through Transforming Growth Factor-β-dependent Modulation of Transcription Factor TCF11
Berg, David T., Gupta, Akanksha, Richardson, Mark A., O'Brien, Lee A., Calnek, David, Grinnell, Brian W.
Published in The Journal of biological chemistry (21.12.2007)
Published in The Journal of biological chemistry (21.12.2007)
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Journal Article
Activated Protein C Decreases Tumor Necrosis Factor–Related Apoptosis-Inducing Ligand by an EPCR- Independent Mechanism Involving Egr-1/Erk-1/2 Activation
O’Brien, Lee A, Richardson, Mark A, Mehrbod, Sean F, Berg, David T, Gerlitz, Bruce, Gupta, Akanksha, Grinnell, Brian W
Published in Arteriosclerosis, thrombosis, and vascular biology (01.12.2007)
Published in Arteriosclerosis, thrombosis, and vascular biology (01.12.2007)
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Journal Article
The role of the FcGRIIIa polymorphism in modifying the association between treatment and outcome in patients with rheumatoid arthritis treated with rituximab versus TNF-α antagonist therapies
Sarsour, Khaled, Greenberg, Jeffrey, Johnston, Joseph A, Nelson, David R, O'Brien, Lee A, Oddoux, Carole, Ostrer, Harry, Pearlman, Alex, Reed, George
Published in Clinical and experimental rheumatology (01.03.2013)
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Published in Clinical and experimental rheumatology (01.03.2013)
Journal Article
Circulating endothelial and endothelial progenitor cells in patients with severe sepsis
Schlichting, Douglas E., Waxman, Aaron B., O'Brien, Lee A., Wang, Tiffany, Naum, Chris C., Rubeiz, George J., Um, Suzane L., Williams, Mark, Betty Yan, Sau-Chi
Published in Microvascular research (01.03.2011)
Published in Microvascular research (01.03.2011)
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Journal Article
ADAMTS13 cleavage efficiency is altered by mutagenic and, to a lesser extent, polymorphic sequence changes in the A1 and A2 domains of von Willebrand factor
Pruss, Cynthia M., Notley, Colleen R. P., Hegadorn, Carol A., O’Brien, Lee A., Lillicrap, David
Published in British journal of haematology (01.11.2008)
Published in British journal of haematology (01.11.2008)
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Journal Article
Founder von Willebrand factor haplotype associated with type 1 von Willebrand disease
O'Brien, Lee A., James, Paula D., Othman, Maha, Berber, Ergul, Cameron, Cherie, Notley, ColleenR.P., Hegadorn, Carol A., Sutherland, Jeffrey J., Hough, Christine, Rivard, Georges E., O'Shaunessey, Denise, Lillicrap, David
Published in Blood (15.07.2003)
Published in Blood (15.07.2003)
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Journal Article
The Puzzling Role of TRAIL in Endothelial Cell Biology
OʼBrien, Lee A, Richardson, Mark A, Berg, David T, Gerlitz, Bruce, Gupta, Akanksha, Grinnell, Brian W
Published in Arteriosclerosis, thrombosis, and vascular biology (01.02.2008)
Published in Arteriosclerosis, thrombosis, and vascular biology (01.02.2008)
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Journal Article
A novel type 2A von Willebrand factor mutation located at the last nucleotide of exon 26 (3538G>A) causes skipping of 2 nonadjacent exons
James, Paula D., O'Brien, Lee A., Hegadorn, Carol A., Notley, Colleen R.P., Sinclair, Gary D., Hough, Christine, Poon, Man-Chiu, Lillicrap, David
Published in Blood (01.11.2004)
Published in Blood (01.11.2004)
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Journal Article
Pruned Receptor Surface Models and Pharmacophores for Three-Dimensional Database Searching
Sutherland, Jeffrey J, O'Brien, Lee A, Weaver, Donald F
Published in Journal of medicinal chemistry (15.07.2004)
Published in Journal of medicinal chemistry (15.07.2004)
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Journal Article
Glycosaminoglycans Bind Factor Xa in a Ca2+-Dependent Fashion and Modulate Its Catalytic Activity
O'Brien, Lee A, Stafford, Alan R, Fredenburgh, James C, Weitz, Jeffrey I
Published in Biochemistry (Easton) (11.11.2003)
Published in Biochemistry (Easton) (11.11.2003)
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Journal Article
Abstract 1738: Assay development for detecting cMET expression in circulating tumor cells (CTC), a potential patient tailoring marker for evaluation of cMET inhibitors
Yan, S Betty, Um, Suzane L., Peek, Victoria L., Yan, Lei, Zeng, Wei, Liu, Ling L., Brandt, John T., Kadam, Sunil, O'Brien, Lee A., Walgren, Richard A.
Published in Cancer research (Chicago, Ill.) (15.04.2012)
Published in Cancer research (Chicago, Ill.) (15.04.2012)
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Journal Article
Negative Regulation of Inducible Nitric-oxide Synthase Expression Mediated through Transforming Growth Factor-β-dependent Modulation of Transcription Factor TCF11
David T. Berg, Akanksha Gupta, Mark A. Richardson, Lee A. O'Brien, David Calnek, Brian W. Grinnell
Published in The Journal of biological chemistry (21.12.2007)
Published in The Journal of biological chemistry (21.12.2007)
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Journal Article