Discovery of New Broad-Spectrum Anti-Infectives for Eukaryotic Pathogens Using Bioorganometallic Chemistry
Lin, Yan, Jung, Hyeim, Bulman, Christina A., Ng, James, Vinck, Robin, O’Beirne, Cillian, Zhong, Shuai, Moser, Matthew S., Tricoche, Nancy, Peguero, Ricardo, Li, Robert W., Urban, Joseph F., Le Pape, Patrice, Pagniez, Fabrice, Moretto, Marco, Weil, Tobias, Lustigman, Sara, Cariou, Kevin, Mitreva, Makedonka, Sakanari, Judy A., Gasser, Gilles
Published in Journal of medicinal chemistry (14.12.2023)
Published in Journal of medicinal chemistry (14.12.2023)
Get full text
Journal Article
In-vitro and in-vivo investigations into the carbene-gold anticancer drug candidates NHC-Au-SCSNMe2 and NHC-Au-S-GLUC against advanced prostate cancer PC3
Walther, Wolfgang, Althagafi, Dhiyaa, Curran, Danielle, O'Beirne, Cillian, Mc Carthy, Cian, Ott, Ingo, Basu, Uttara, Büttner, Britta, Sterner-Kock, Anja, Müller-Bunz, Helge, Sánchez-Sanz, Goar, Zhu, Xiangming, Tacke, Matthias
Published in Anti-cancer drugs (01.08.2020)
Published in Anti-cancer drugs (01.08.2020)
Get more information
Journal Article
The Antibacterial Drug Candidate SBC3 is a Potent Inhibitor of Bacterial Thioredoxin Reductase
O'Loughlin, Jennie, Napolitano, Silvia, Alkhathami, Fahad, O'Beirne, Cillian, Marhöfer, Daniel, O'Shaughnessy, Megan, Howe, Orla, Tacke, Matthias, Rubini, Marina
Published in Chembiochem : a European journal of chemical biology (16.03.2021)
Published in Chembiochem : a European journal of chemical biology (16.03.2021)
Get full text
Journal Article
Silver N-heterocyclic carbene complexes are potent uncompetitive inhibitors of the papain-like protease with antiviral activity against SARS-CoV-2
Gil-Moles, Maria, O'Beirne, Cillian, Esarev, Igor V, Lippmann, Petra, Tacke, Matthias, Cinatl, Jindrich, Bojkova, Denisa, Ott, Ingo
Published in MedChemComm (20.07.2023)
Published in MedChemComm (20.07.2023)
Get full text
Journal Article
Synthesis, structures and antimicrobial activity of novel NHC∗- and Ph3P-Ag(I)-Benzoate derivatives
O'Beirne, Cillian, Alhamad, Nada F., Ma, Qinxi, Müller-Bunz, Helge, Kavanagh, Kevin, Butler, Geraldine, Zhu, Xiangming, Tacke, Matthias
Published in Inorganica Chimica Acta (24.02.2019)
Published in Inorganica Chimica Acta (24.02.2019)
Get full text
Journal Article
Novel derivatives of the antibiotic NHC-Ag(I) drug candidate SBC3: Synthesis, biological evaluation and Ag-109 NMR studies
O'Beirne, Cillian, Althani, Hessah T., Dada, Oyinlola, Cassidy, Jennifer, Kavanagh, Kevin, Muller-Bunz, Helge, Ortin, Yannick, Zhu, Xiangming, Tacke, Matthias
Published in Polyhedron (15.07.2018)
Published in Polyhedron (15.07.2018)
Get full text
Journal Article
Continuous flow synthesis and antimicrobial evaluation of NHC silver carboxylate derivatives of SBC3 in vitro and in vivo
O'Beirne, Cillian, Piatek, Magdalena E, Fossen, Jen, Müller-Bunz, Helge, Andes, David R, Kavanagh, Kevin, Patil, Siddappa A, Baumann, Marcus, Tacke, Matthias
Published in Metallomics (17.02.2021)
Published in Metallomics (17.02.2021)
Get more information
Journal Article
Novel derivatives of the antibiotic NHC–Ag(I) drug candidate SBC3: Synthesis, biological evaluation and 109Ag NMR studies
O'Beirne, Cillian, Althani, Hessah T., Dada, Oyinlola, Cassidy, Jennifer, Kavanagh, Kevin, Müller-Bunz, Helge, Ortin, Yannick, Zhu, Xiangming, Tacke, Matthias
Published in Polyhedron (15.07.2018)
Published in Polyhedron (15.07.2018)
Get full text
Journal Article
The non-isomorphous crystal structures of NHC-Au-Cl and NHC-Au-Br (NHC is 1,3-dibenzyl-4,5-diphenylimidazol-2-ylidene)
Tacke, Matthias, Dada, Oyinlola, O'Beirne, Cillian, Zhu, Xiangming, Müller-Bunz, Helge
Published in Acta crystallographica. Section C, Crystal structure communications (01.11.2016)
Published in Acta crystallographica. Section C, Crystal structure communications (01.11.2016)
Get full text
Journal Article
Discovery of New Broad-Spectrum Anti-Infectives for Eukaryotic Pathogens Using Bioorganometallic Chemistry
Lin, Yan, Jung, Hyeim, Bulman, Christina A, Ng, James, Vinck, Robin, O'Beirne, Cillian, Moser, Matthew S, Tricoche, Nancy, Peguero, Ricardo, Li, Robert W, Urban, Joseph F, Pape, Patrice Le, Pagniez, Fabrice, Moretto, Marco, Weil, Tobias, Lustigman, Sara, Cariou, Kevin, Mitreva, Makedonka, Sakanari, Judy A, Gasser, Gilles
Published in bioRxiv : the preprint server for biology (30.06.2023)
Get more information
Published in bioRxiv : the preprint server for biology (30.06.2023)
Journal Article