Brain and blood metabolite signatures of pathology and progression in Alzheimer disease: A targeted metabolomics study
Varma, Vijay R, Oommen, Anup M, Varma, Sudhir, Casanova, Ramon, An, Yang, Andrews, Ryan M, O'Brien, Richard, Pletnikova, Olga, Troncoso, Juan C, Toledo, Jon, Baillie, Rebecca, Arnold, Matthias, Kastenmueller, Gabi, Nho, Kwangsik, Doraiswamy, P Murali, Saykin, Andrew J, Kaddurah-Daouk, Rima, Legido-Quigley, Cristina, Thambisetty, Madhav
Published in PLoS medicine (25.01.2018)
Published in PLoS medicine (25.01.2018)
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Dysregulation of multiple metabolic networks related to brain transmethylation and polyamine pathways in Alzheimer disease: A targeted metabolomic and transcriptomic study
Mahajan, Uma V, Varma, Vijay R, Griswold, Michael E, Blackshear, Chad T, An, Yang, Oommen, Anup M, Varma, Sudhir, Troncoso, Juan C, Pletnikova, Olga, O'Brien, Richard, Hohman, Timothy J, Legido-Quigley, Cristina, Thambisetty, Madhav
Published in PLoS medicine (01.01.2020)
Published in PLoS medicine (01.01.2020)
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Long-term cortisol measures predict Alzheimer disease risk
Ennis, Gilda E, An, Yang, Resnick, Susan M, Ferrucci, Luigi, O'Brien, Richard J, Moffat, Scott D
Published in Neurology (24.01.2017)
Published in Neurology (24.01.2017)
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Personality and risk of Alzheimer's disease: New data and meta-analysis
Terracciano, Antonio, Sutin, Angelina R, An, Yang, O'Brien, Richard J, Ferrucci, Luigi, Zonderman, Alan B, Resnick, Susan M
Published in Alzheimer's & dementia (01.03.2014)
Published in Alzheimer's & dementia (01.03.2014)
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Evidence for brain glucose dysregulation in Alzheimer's disease
An, Yang, Varma, Vijay R., Varma, Sudhir, Casanova, Ramon, Dammer, Eric, Pletnikova, Olga, Chia, Chee W., Egan, Josephine M., Ferrucci, Luigi, Troncoso, Juan, Levey, Allan I., Lah, James, Seyfried, Nicholas T., Legido-Quigley, Cristina, O'Brien, Richard, Thambisetty, Madhav
Published in Alzheimer's & dementia (01.03.2018)
Published in Alzheimer's & dementia (01.03.2018)
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Magnetic resonance imaging of mouse brain networks plasticity following motor learning
Badea, Alexandra, Ng, Kwan L, Anderson, Robert J, Zhang, Jiangyang, Miller, Michael I, O'Brien, Richard J
Published in PloS one (08.05.2019)
Published in PloS one (08.05.2019)
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Chronic Glucocorticoid Exposure Induced an S1PR2-RORγ Axis to Enhance Hepatic Gluconeogenesis in Male Mice
Lee, Rebecca A, Chang, Maggie, Tsay, Ariel, Lee, Yeong Rim, Li, Danielle, Yiv, Nicholas, Tian, Sharon, Zhao, Michelle, O'Brien, Richard M, Wang, Jen-Chywan
Published in Diabetes (New York, N.Y.) (01.11.2023)
Published in Diabetes (New York, N.Y.) (01.11.2023)
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Changes in brain function occur years before the onset of cognitive impairment
Beason-Held, Lori L, Goh, Joshua O, An, Yang, Kraut, Michael A, O'Brien, Richard J, Ferrucci, Luigi, Resnick, Susan M
Published in The Journal of neuroscience (13.11.2013)
Published in The Journal of neuroscience (13.11.2013)
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Exploratory Assessment of Proteomic Network Changes in Cerebrospinal Fluid of Mild Cognitive Impairment Patients: A Pilot Study
Kamalian, Aida, Ho, Sara G, Patel, Megha, Lewis, Alexandria, Bakker, Arnold, Albert, Marilyn, O'Brien, Richard J, Moghekar, Abhay, Lutz, Michael W
Published in Biomolecules (Basel, Switzerland) (01.07.2023)
Published in Biomolecules (Basel, Switzerland) (01.07.2023)
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G6PC1 and G6PC2 influence G6P flux but not HSD11B1 activity
Hawes, Emily M, Boortz, Kayla A, Oeser, James K, O'Rourke, Margaret L, O'Brien, Richard M
Published in Journal of molecular endocrinology (01.11.2023)
Published in Journal of molecular endocrinology (01.11.2023)
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Identifying vulnerable brain networks associated with Alzheimer’s disease risk
Mahzarnia, Ali, Stout, Jacques A, Anderson, Robert J, Moon, Hae Sol, Yar Han, Zay, Beck, Kate, Browndyke, Jeffrey N, Dunson, David B, Johnson, Kim G, O’Brien, Richard J, Badea, Alexandra
Published in Cerebral cortex (New York, N.Y. 1991) (25.04.2023)
Published in Cerebral cortex (New York, N.Y. 1991) (25.04.2023)
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Bile acid synthesis, modulation, and dementia: A metabolomic, transcriptomic, and pharmacoepidemiologic study
Varma, Vijay R, Wang, Youjin, An, Yang, Varma, Sudhir, Bilgel, Murat, Doshi, Jimit, Legido-Quigley, Cristina, Delgado, João C, Oommen, Anup M, Roberts, Jackson A, Wong, Dean F, Davatzikos, Christos, Resnick, Susan M, Troncoso, Juan C, Pletnikova, Olga, O'Brien, Richard, Hak, Eelko, Baak, Brenda N, Pfeiffer, Ruth, Baloni, Priyanka, Mohmoudiandehkordi, Siamak, Nho, Kwangsik, Kaddurah-Daouk, Rima, Bennett, David A, Gadalla, Shahinaz M, Thambisetty, Madhav
Published in PLoS medicine (27.05.2021)
Published in PLoS medicine (27.05.2021)
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Nonsynonymous single-nucleotide polymorphisms in the G6PC2 gene affect protein expression, enzyme activity, and fasting blood glucose
Overway, Emily M., Bosma, Karin J., Claxton, Derek P., Oeser, James K., Singh, Kritika, Breidenbach, Lindsay B., Mchaourab, Hassane S., Davis, Lea K., O'Brien, Richard M.
Published in The Journal of biological chemistry (01.02.2022)
Published in The Journal of biological chemistry (01.02.2022)
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